Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ADRM1 | ADRM1 | Q16186 | Proteasomal ubiquitin receptor ADRM1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 296 | 40 | 40 | 0 |
AES_ENST00000327141 | TLE5 | Q08117 | TLE family member 5 | chr19 | Not Cancer Driver | No | 1 | intact | 16 | 77 | 7 | 7 | 0 |
AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | Census, Compendium | Yes | 1 | hippie | 108 | 158 | 24 | 24 | 4 |
AMFR | AMFR | Q9UKV5 | E3 ubiquitin-protein ligase AMFR | chr16 | Not Cancer Driver | No | 1 | hippie | 73 | 229 | 30 | 30 | 0 |
APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
AR | AR | P10275 | Androgen receptor | chrX | Census, Compendium | Yes | 1 | hippie | 196 | 443 | 88 | 88 | 169 |
ATXN1 | ATXN1 | P54253 | Ataxin-1 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 193 | 604 | 168 | 168 | 0 |
ATXN3 | ATXN3 | P54252 | Ataxin-3 | chr14 | Not Cancer Driver | No | 1 | hippie | 46 | 181 | 24 | 24 | 0 |
BAG3 | BAG3 | O95817 | BAG family molecular chaperone regulator 3 | chr10 | Not Cancer Driver | No | 1 | hippie | 57 | 571 | 57 | 57 | 7 |
BCL6_ENST00000232014 | BCL6 | P41182 | B-cell lymphoma 6 protein | chr3 | Census, Compendium | Yes | 1 | hippie | 134 | 328 | 67 | 67 | 0 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
C1orf109 | C1orf109 | Q9NX04 | Uncharacterized protein C1orf109 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 17 | 0 | 0 | 0 | 0 |
CCDC57_ENST00000392347 | CCDC57 | Q2TAC2 | Coiled-coil domain-containing protein 57 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 107 | 595 | 65 | 65 | 0 |
CCDC74A | CCDC74A | Q96AQ1 | Coiled-coil domain-containing protein 74A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 351 | 84 | 84 | 0 |
CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 221 | 23 | 23 | 3 |
CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 1 | hippie | 287 | 145 | 18 | 18 | 151 |
CLIC4 | CLIC4 | Q9Y696 | Chloride intracellular channel protein 4 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 49 | 4 | 4 | 0 |
CNOT2 | CNOT2 | Q9NZN8 | CCR4-NOT transcription complex subunit 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 84 | 354 | 66 | 66 | 0 |
CPSF2 | CPSF2 | Q9P2I0 | Cleavage and polyadenylation specificity factor subunit 2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 231 | 22 | 22 | 0 |
CRBN | CRBN | Q96SW2 | Protein cereblon | chr3 | Not Cancer Driver | No | 1 | hippie | 52 | 76 | 10 | 10 | 1 |
CUL1_ENST00000602748 | CUL1 | Q13616 | Cullin-1 | chr7 | Not Cancer Driver | No | 2 | intact, hippie | 151 | 65 | 9 | 9 | 0 |
CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | Not Cancer Driver | No | 1 | hippie | 188 | 372 | 41 | 41 | 3 |
DAG1_ENST00000515359 | DAG1 | Q14118 | Dystroglycan 1 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 102 | 485 | 61 | 61 | 4 |
DDB2 | DDB2 | Q92466 | DNA damage-binding protein 2 | chr11 | Census, Compendium | Yes | 1 | hippie | 45 | 70 | 5 | 5 | 2 |
DDX58 | DDX58 | O95786 | Antiviral innate immune response receptor RIG-I | chr9 | Not Cancer Driver | No | 1 | hippie | 118 | 61 | 10 | 10 | 2 |
DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 132 | 514 | 82 | 82 | 0 |
DTX2 | DTX2 | Q86UW9 | Probable E3 ubiquitin-protein ligase DTX2 | chr7 | Not Cancer Driver | No | 1 | hippie | 84 | 292 | 42 | 42 | 0 |
DUSP4 | DUSP4 | Q13115 | Dual specificity protein phosphatase 4 | chr8 | Not Cancer Driver | No | 1 | hippie | 43 | 63 | 9 | 9 | 0 |
EEF1A1 | EEF1A1 | P68104 | Elongation factor 1-alpha 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 109 | 100 | 14 | 14 | 0 |
EPB41L1 | EPB41L1 | Q9H4G0 | Band 4.1-like protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 151 | 577 | 109 | 109 | 1 |
EPHA7 | EPHA7 | Q15375 | Ephrin type-A receptor 7 | chr6 | Census, Compendium | Yes | 1 | intact | 280 | 71 | 15 | 15 | 0 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
FBXO38_ENST00000340253 | FBXO38 | Q6PIJ6 | F-box only protein 38 | chr5 | Not Cancer Driver | No | 1 | hippie | 133 | 440 | 48 | 48 | 1 |
FBXO7 | FBXO7 | Q9Y3I1 | F-box only protein 7 | chr22 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 75 | 243 | 38 | 38 | 1 |
FEV | FEV | Q99581 | Protein FEV | chr2 | Census | Yes | 1 | hippie | 15 | 55 | 0 | 0 | 0 |
FOXJ3 | FOXJ3 | Q9UPW0 | Forkhead box protein J3 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 77 | 459 | 54 | 54 | 0 |
FOXP3 | FOXP3 | Q9BZS1 | Forkhead box protein P3 | chrX | Not Cancer Driver | No | 1 | hippie | 38 | 186 | 16 | 16 | 10 |
FSCN1 | FSCN1 | Q16658 | Fascin | chr7 | Not Cancer Driver | No | 1 | hippie | 58 | 81 | 5 | 5 | 0 |
FSD2 | FSD2 | A1L4K1 | Fibronectin type III and SPRY domain-containing protein 2 | chr15 | Not Cancer Driver | No | 1 | hippie | 116 | 300 | 60 | 60 | 0 |
FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
GABARAPL1_ENST00000545887 | GABARAPL1 | Q9H0R8 | Gamma-aminobutyric acid receptor-associated protein-like 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 19 | 10 | 1 | 1 | 0 |
GCA | GCA | P28676 | Grancalcin | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 29 | 1 | 1 | 0 |
H2AFX | H2AX | P16104 | Histone H2AX | chr11 | Not Cancer Driver | No | 1 | intact | 20 | 68 | 10 | 10 | 0 |
HEMK1_ENST00000455834 | HEMK1 | Q9Y5R4 | MTRF1L release factor glutamine methyltransferase | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 14 | 0 | 0 | 0 |
HERC2 | HERC2 | O95714 | E3 ubiquitin-protein ligase HERC2 | chr15 | Compendium | Yes | 1 | hippie | 718 | 971 | 150 | 150 | 1 |
HGS | HGS | O14964 | Hepatocyte growth factor-regulated tyrosine kinase substrate | chr17 | Not Cancer Driver | No | 1 | hippie | 109 | 528 | 74 | 74 | 0 |
HLA-B | HLA-B | P01889 | HLA class I histocompatibility antigen, B alpha chain | chr6 | Compendium | Yes | 1 | hippie | 78 | 169 | 34 | 34 | 0 |
HLA-C | HLA-C | P10321 | HLA class I histocompatibility antigen, C alpha chain | chr6 | Not Cancer Driver | No | 1 | hippie | 104 | 175 | 58 | 58 | 0 |
HNRNPA1 | HNRNPA1 | P09651 | Heterogeneous nuclear ribonucleoprotein A1 | chr12 | Not Cancer Driver | No | 1 | hippie | 70 | 290 | 58 | 58 | 4 |
HNRNPA2B1 | HNRNPA2B1 | P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 | chr7 | Census, Compendium | Yes | 1 | hippie | 68 | 255 | 41 | 41 | 0 |
HTRA4 | HTRA4 | P83105 | Serine protease HTRA4 | chr8 | Not Cancer Driver | No | 1 | hippie | 57 | 15 | 0 | 0 | 0 |
IKBKE | IKBKE | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 108 | 76 | 13 | 13 | 0 |
IQCB1 | IQCB1 | Q15051 | IQ calmodulin-binding motif-containing protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 72 | 88 | 8 | 8 | 0 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
KANK2_ENST00000586659 | KANK2 | Q63ZY3 | KN motif and ankyrin repeat domain-containing protein 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 107 | 531 | 71 | 71 | 3 |
KIF5B | KIF5B | P33176 | Kinesin-1 heavy chain | chr10 | Census, Compendium | Yes | 1 | hippie | 122 | 586 | 67 | 67 | 0 |
KLF15 | KLF15 | Q9UIH9 | Krueppel-like factor 15 | chr3 | Not Cancer Driver | No | 1 | hippie | 66 | 273 | 48 | 48 | 0 |
KLF16 | KLF16 | Q9BXK1 | Krueppel-like factor 16 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 13 | 204 | 8 | 8 | 0 |
KLF8 | KLF8 | O95600 | Krueppel-like factor 8 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 71 | 270 | 53 | 53 | 0 |
KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 1 | hippie | 788 | 7 | 2 | 2 | 27 |
KRTAP19-5 | KRTAP19-5 | Q3LI72 | Keratin-associated protein 19-5 | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 35 | 0 | 0 | 0 | 0 |
L3MBTL1 | L3MBTL1 | Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 116 | 447 | 40 | 40 | 0 |
LARP7_ENST00000344442 | LARP7 | Q4G0J3 | La-related protein 7 | chr4 | Not Cancer Driver | No | 1 | hippie | 58 | 350 | 44 | 44 | 0 |
LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
MAPK6 | MAPK6 | Q16659 | Mitogen-activated protein kinase 6 | chr15 | Not Cancer Driver | No | 1 | hippie | 79 | 165 | 20 | 20 | 0 |
MBL2 | MBL2 | P11226 | Mannose-binding protein C | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 122 | 32 | 32 | 0 |
MFN2_ENST00000444836 | MFN2 | O95140 | Mitofusin-2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 81 | 9 | 9 | 20 |
MID1 | MID1 | O15344 | E3 ubiquitin-protein ligase Midline-1 | chrX | Not Cancer Driver | No | 1 | hippie | 86 | 86 | 16 | 16 | 4 |
MTMR10 | MTMR10 | Q9NXD2 | Myotubularin-related protein 10 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 79 | 98 | 7 | 7 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
MYOZ3_ENST00000517768 | MYOZ3 | Q8TDC0 | Myozenin-3 | chr5 | Not Cancer Driver | No | 1 | hippie | 40 | 211 | 27 | 27 | 0 |
NELFE | NELFE | P18615 | Negative elongation factor E | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 352 | 45 | 45 | 0 |
NHLRC2 | NHLRC2 | Q8NBF2 | NHL repeat-containing protein 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 74 | 103 | 12 | 12 | 0 |
NME2 | NME2 | P22392 | Nucleoside diphosphate kinase B | chr17 | Not Cancer Driver | No | 1 | hippie | 13 | 11 | 1 | 1 | 0 |
NRBP2 | NRBP2 | Q9NSY0 | Nuclear receptor-binding protein 2 | chr8 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 30 | 110 | 5 | 5 | 0 |
NUB1_ENST00000470229 | NUB1 | Q9Y5A7 | NEDD8 ultimate buster 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 52 | 180 | 15 | 15 | 0 |
OAZ1 | OAZ1 | P54368 | Ornithine decarboxylase antizyme 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 109 | 12 | 12 | 0 |
OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 233 | 553 | 60 | 60 | 0 |
OPTN_ENST00000263036 | OPTN | Q96CV9 | Optineurin | chr10 | Not Cancer Driver | No | 1 | hippie | 58 | 470 | 51 | 51 | 6 |
P2RY6_ENST00000540342 | P2RY6 | Q15077 | P2Y purinoceptor 6 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 10 | 5 | 5 | 0 |
P4HA3_ENST00000331597 | P4HA3 | Q7Z4N8 | Prolyl 4-hydroxylase subunit alpha-3 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 70 | 17 | 2 | 2 | 0 |
PCK1 | PCK1 | P35558 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | chr20 | Not Cancer Driver | No | 1 | hippie | 142 | 110 | 28 | 28 | 1 |
PDIA5 | PDIA5 | Q14554 | Protein disulfide-isomerase A5 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 79 | 9 | 9 | 0 |
PEX19 | PEX19 | P40855 | Peroxisomal biogenesis factor 19 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 266 | 38 | 38 | 0 |
PFDN5 | PFDN5 | Q99471 | Prefoldin subunit 5 | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 3 | 0 | 0 | 0 |
PITX2_ENST00000354925 | PITX2 | Q99697 | Pituitary homeobox 2 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 74 | 185 | 43 | 43 | 13 |
PKN1_ENST00000242783 | PKN1 | Q16512 | Serine/threonine-protein kinase N1 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 120 | 459 | 54 | 54 | 0 |
PLK1 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | Not Cancer Driver | No | 1 | hippie | 87 | 119 | 13 | 13 | 0 |
POMP | POMP | Q9Y244 | Proteasome maturation protein | chr13 | Not Cancer Driver | No | 4 | hippie, biogrid | 16 | 41 | 7 | 7 | 0 |
PPL | PPL | O60437 | Periplakin | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 219 | 1133 | 133 | 133 | 0 |
PRKCA | PRKCA | P17252 | Protein kinase C alpha type | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 94 | 154 | 22 | 22 | 0 |
PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
PROP1 | PROP1 | O75360 | Homeobox protein prophet of Pit-1 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 35 | 194 | 32 | 32 | 7 |
PRPF19 | PRPF19 | Q9UMS4 | Pre-mRNA-processing factor 19 | chr11 | Not Cancer Driver | No | 1 | hippie | 71 | 109 | 16 | 16 | 0 |
PSMA1_ENST00000396394 | PSMA1 | P25786 | Proteasome subunit alpha type-1 | chr11 | Not Cancer Driver | No | 10 | intact, hippie, biogrid | 48 | 51 | 9 | 9 | 0 |
PSMA2 | PSMA2 | P25787 | Proteasome subunit alpha type-2 | chr7 | Not Cancer Driver | No | 7 | intact, hippie, biogrid | 20 | 0 | 0 | 0 | 0 |
PSMA3 | PSMA3 | P25788 | Proteasome subunit alpha type-3 | chr14 | Not Cancer Driver | No | 7 | intact, hippie, biogrid | 27 | 30 | 5 | 5 | 0 |
PSMA4_ENST00000559082 | PSMA4 | P25789 | Proteasome subunit alpha type-4 | chr15 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 29 | 28 | 9 | 9 | 0 |
PSMA5 | PSMA5 | P28066 | Proteasome subunit alpha type-5 | chr1 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 24 | 23 | 1 | 1 | 0 |
PSMA6 | PSMA6 | P60900 | Proteasome subunit alpha type-6 | chr14 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 37 | 2 | 1 | 1 | 0 |
PSMA7 | PSMA7 | O14818 | Proteasome subunit alpha type-7 | chr20 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 24 | 23 | 1 | 1 | 0 |
PSMA8 | PSMA8 | Q8TAA3 | Proteasome subunit alpha-type 8 | chr18 | Not Cancer Driver | No | 5 | hippie, biogrid | 42 | 15 | 5 | 5 | 0 |
PSMB1 | PSMB1 | P20618 | Proteasome subunit beta type-1 | chr6 | Not Cancer Driver | No | 7 | intact, hippie, biogrid | 25 | 14 | 2 | 2 | 0 |
PSMB10 | PSMB10 | P40306 | Proteasome subunit beta type-10 | chr16 | Not Cancer Driver | No | 4 | hippie, biogrid | 22 | 36 | 5 | 5 | 0 |
PSMB2 | PSMB2 | P49721 | Proteasome subunit beta type-2 | chr1 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
PSMB5 | PSMB5 | P28074 | Proteasome subunit beta type-5 | chr14 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 39 | 9 | 0 | 0 | 0 |
PSMB6 | PSMB6 | P28072 | Proteasome subunit beta type-6 | chr17 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 19 | 22 | 1 | 1 | 0 |
PSMB7 | PSMB7 | Q99436 | Proteasome subunit beta type-7 | chr9 | Not Cancer Driver | No | 7 | intact, hippie, biogrid | 25 | 26 | 3 | 3 | 0 |
PSMB8 | PSMB8 | P28062 | Proteasome subunit beta type-8 | chr6 | Not Cancer Driver | No | 4 | hippie, biogrid | 43 | 62 | 7 | 7 | 3 |
PSMB9 | PSMB9 | P28065 | Proteasome subunit beta type-9 | chr6 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 21 | 17 | 1 | 1 | 1 |
PSMC1 | PSMC1 | P62191 | 26S proteasome regulatory subunit 4 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 165 | 10 | 10 | 0 |
PSMC2_ENST00000292644 | PSMC2 | P35998 | 26S proteasome regulatory subunit 7 | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 63 | 120 | 13 | 13 | 0 |
PSMC3_ENST00000298852 | PSMC3 | P17980 | 26S proteasome regulatory subunit 6A | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 55 | 131 | 10 | 10 | 0 |
PSMC4 | PSMC4 | P43686 | 26S proteasome regulatory subunit 6B | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 21 | 3 | 3 | 0 |
PSMC5 | PSMC5 | P62195 | 26S proteasome regulatory subunit 8 | chr17 | Not Cancer Driver | No | 3 | hippie, biogrid | 52 | 64 | 6 | 6 | 0 |
PSMC6_ENST00000606149 | PSMC6 | P62333 | 26S proteasome regulatory subunit 10B | chr14 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 49 | 69 | 8 | 8 | 0 |
PSMD1 | PSMD1 | Q99460 | 26S proteasome non-ATPase regulatory subunit 1 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 110 | 201 | 19 | 19 | 0 |
PSMD11_ENST00000457654 | PSMD11 | O00231 | 26S proteasome non-ATPase regulatory subunit 11 | chr17 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 51 | 0 | 0 | 0 | 0 |
PSMD12 | PSMD12 | O00232 | 26S proteasome non-ATPase regulatory subunit 12 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 24 | 3 | 3 | 0 |
PSMD13_ENST00000532097 | PSMD13 | Q9UNM6 | 26S proteasome non-ATPase regulatory subunit 13 | chr11 | Not Cancer Driver | No | 3 | hippie, biogrid | 30 | 13 | 3 | 3 | 0 |
PSMD14 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 23 | 67 | 6 | 6 | 0 |
PSMD2 | PSMD2 | Q13200 | 26S proteasome non-ATPase regulatory subunit 2 | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 100 | 135 | 14 | 14 | 0 |
PSMD3 | PSMD3 | O43242 | 26S proteasome non-ATPase regulatory subunit 3 | chr17 | Not Cancer Driver | No | 3 | hippie, biogrid | 69 | 152 | 19 | 19 | 0 |
PSMD4_ENST00000368884 | PSMD4 | P55036 | 26S proteasome non-ATPase regulatory subunit 4 | chr1 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 43 | 243 | 25 | 25 | 0 |
PSMD5 | PSMD5 | Q16401 | 26S proteasome non-ATPase regulatory subunit 5 | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 43 | 2 | 1 | 1 | 0 |
PSMD6_ENST00000295901 | PSMD6 | Q15008 | 26S proteasome non-ATPase regulatory subunit 6 | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 33 | 40 | 3 | 3 | 0 |
PSMD7 | PSMD7 | P51665 | 26S proteasome non-ATPase regulatory subunit 7 | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 39 | 70 | 4 | 4 | 0 |
PSMD8 | PSMD8 | P48556 | 26S proteasome non-ATPase regulatory subunit 8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 78 | 2 | 2 | 0 |
PSMD9 | PSMD9 | O00233 | 26S proteasome non-ATPase regulatory subunit 9 | chr12 | Not Cancer Driver | No | 1 | hippie | 22 | 173 | 16 | 16 | 0 |
PSME1_ENST00000206451 | PSME1 | Q06323 | Proteasome activator complex subunit 1 | chr14 | Not Cancer Driver | No | 3 | hippie, biogrid | 20 | 80 | 8 | 8 | 0 |
PSME2 | PSME2 | Q9UL46 | Proteasome activator complex subunit 2 | chr14 | Not Cancer Driver | No | 3 | hippie, biogrid | 32 | 39 | 3 | 3 | 0 |
PSME3_ENST00000590720 | PSME3 | P61289 | Proteasome activator complex subunit 3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 25 | 5 | 5 | 0 |
PSME4 | PSME4 | Q14997 | Proteasome activator complex subunit 4 | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 214 | 134 | 12 | 12 | 0 |
PSMF1_ENST00000333082 | PSMF1 | Q92530 | Proteasome inhibitor PI31 subunit | chr20 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 45 | 140 | 26 | 26 | 0 |
PSMG1 | PSMG1 | O95456 | Proteasome assembly chaperone 1 | chr21 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 31 | 25 | 1 | 1 | 0 |
PSMG2 | PSMG2 | Q969U7 | Proteasome assembly chaperone 2 | chr18 | Not Cancer Driver | No | 4 | hippie, biogrid | 19 | 3 | 0 | 0 | 0 |
PSMG3_ENST00000252329 | PSMG3 | Q9BT73 | Proteasome assembly chaperone 3 | chr7 | Not Cancer Driver | No | 1 | hippie | 18 | 1 | 0 | 0 | 0 |
PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | Census, Compendium | Yes | 1 | hippie | 129 | 260 | 38 | 38 | 60 |
PTPN2 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | Not Cancer Driver | No | 1 | hippie | 57 | 120 | 14 | 14 | 0 |
RAB11A | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | Not Cancer Driver | No | 1 | hippie | 31 | 43 | 4 | 4 | 0 |
RAD23A | RAD23A | P54725 | UV excision repair protein RAD23 homolog A | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 283 | 41 | 41 | 0 |
RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
RIPK1_ENST00000380409 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | Compendium | Yes | 1 | intact, hippie, biogrid | 82 | 277 | 39 | 39 | 4 |
RNF11 | RNF11 | Q9Y3C5 | RING finger protein 11 | chr1 | Not Cancer Driver | No | 1 | hippie | 17 | 76 | 7 | 7 | 0 |
RPP38_ENST00000378202 | RPP38 | P78345 | Ribonuclease P protein subunit p38 | chr10 | Not Cancer Driver | No | 1 | hippie | 36 | 118 | 19 | 19 | 0 |
SEM1_ENST00000356686 | SEM1 | Q6ZVN7 | Putative protein SEM1, isoform 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 2 | 52 | 1 | 1 | 0 |
SHLD3 | SHLD3 | Q6ZNX1 | Shieldin complex subunit 3 | chr5 | Not Cancer Driver | No | 1 | intact | 3 | 81 | 1 | 1 | 0 |
SKP1_ENST00000517625 | SKP1 | P63208 | S-phase kinase-associated protein 1 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 19 | 95 | 17 | 17 | 0 |
SLC16A11 | SLC16A11 | Q8NCK7 | Monocarboxylate transporter 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 33 | 72 | 5 | 5 | 0 |
SLX4 | SLX4 | Q8IY92 | Structure-specific endonuclease subunit SLX4 | chr16 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 271 | 1573 | 232 | 232 | 0 |
SMAD1 | SMAD1 | Q15797 | Mothers against decapentaplegic homolog 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 54 | 161 | 22 | 22 | 0 |
SMG7_ENST00000347615 | SMG7 | Q92540 | Nonsense-mediated mRNA decay factor SMG7 | chr1 | Not Cancer Driver | No | 1 | hippie | 134 | 664 | 82 | 82 | 0 |
SOHLH1_ENST00000298466 | SOHLH1 | Q5JUK2 | Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 48 | 252 | 39 | 39 | 0 |
SPG21_ENST00000433215 | SPG21 | Q9NZD8 | Maspardin | chr15 | Not Cancer Driver | No | 1 | hippie | 31 | 13 | 1 | 1 | 0 |
SQSTM1 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | Not Cancer Driver | No | 1 | hippie | 54 | 267 | 32 | 32 | 30 |
STK24 | STK24 | Q9Y6E0 | Serine/threonine-protein kinase 24 | chr13 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 67 | 118 | 16 | 16 | 0 |
STK32C | STK32C | Q86UX6 | Serine/threonine-protein kinase 32C | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 172 | 10 | 10 | 0 |
SYAP1 | SYAP1 | Q96A49 | Synapse-associated protein 1 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 221 | 22 | 22 | 0 |
SYNPO2L | SYNPO2L | Q9H987 | Synaptopodin 2-like protein | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 103 | 950 | 99 | 99 | 0 |
SYVN1 | SYVN1 | Q86TM6 | E3 ubiquitin-protein ligase synoviolin | chr11 | Not Cancer Driver | No | 1 | hippie | 63 | 284 | 32 | 32 | 0 |
TARDBP | TARDBP | Q13148 | TAR DNA-binding protein 43 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 51 | 202 | 15 | 15 | 27 |
TEKT5 | TEKT5 | Q96M29 | Tektin-5 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 100 | 70 | 16 | 16 | 0 |
TFAP2D | TFAP2D | Q7Z6R9 | Transcription factor AP-2-delta | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 164 | 161 | 54 | 54 | 0 |
TNIP2 | TNIP2 | Q8NFZ5 | TNFAIP3-interacting protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 43 | 316 | 36 | 36 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | intact, hippie | 2891 | 282 | 1466 | 1466 | 83 |
TPTE2 | TPTE2 | Q6XPS3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 | chr13 | Not Cancer Driver | No | 1 | hippie | 210 | 33 | 13 | 13 | 0 |
TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 67 | 62 | 7 | 7 | 0 |
U2AF2 | U2AF2 | P26368 | Splicing factor U2AF 65 kDa subunit | chr19 | Compendium | Yes | 1 | hippie, biogrid | 78 | 191 | 28 | 28 | 0 |
UBA2 | UBA2 | Q9UBT2 | SUMO-activating enzyme subunit 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 219 | 33 | 33 | 0 |
UBD | UBD | O15205 | Ubiquitin D | chr6 | Not Cancer Driver | No | 1 | hippie | 31 | 8 | 1 | 1 | 0 |
UBE2M | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 32 | 6 | 6 | 0 |
UBE3A | UBE3A | Q05086 | Ubiquitin-protein ligase E3A | chr15 | Not Cancer Driver | No | 1 | hippie | 141 | 136 | 22 | 22 | 0 |
UCHL5 | UCHL5 | Q9Y5K5 | Ubiquitin carboxyl-terminal hydrolase isozyme L5 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 33 | 41 | 7 | 7 | 0 |
UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 141 | 24 | 24 | 0 |
USP14 | USP14 | P54578 | Ubiquitin carboxyl-terminal hydrolase 14 | chr18 | Not Cancer Driver | No | 1 | hippie | 59 | 86 | 6 | 6 | 0 |
USP15 | USP15 | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | chr12 | Not Cancer Driver | No | 1 | hippie | 136 | 259 | 39 | 39 | 0 |
USP7 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | Not Cancer Driver | No | 1 | hippie | 170 | 215 | 45 | 45 | 0 |
USP9X_ENST00000378308 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | Census, Compendium | Yes | 1 | hippie, biogrid | 339 | 405 | 51 | 51 | 1 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | Not Cancer Driver | No | 1 | hippie | 51 | 489 | 49 | 49 | 0 |
YBX1 | YBX1 | P67809 | Y-box-binding protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 312 | 41 | 41 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|