Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AAR2_ENST00000320849 | AAR2 | Q9Y312 | Protein AAR2 homolog | chr20 | Not Cancer Driver | No | 1 | hippie | 56 | 28 | 6 | 6 | 0 |
ABCE1 | ABCE1 | P61221 | ATP-binding cassette sub-family E member 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 74 | 36 | 6 | 6 | 0 |
ADRM1 | ADRM1 | Q16186 | Proteasomal ubiquitin receptor ADRM1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 296 | 40 | 40 | 0 |
AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
AKIRIN1 | AKIRIN1 | Q9H9L7 | Akirin-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 125 | 9 | 9 | 0 |
AKIRIN2 | AKIRIN2 | Q53H80 | Akirin-2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 119 | 11 | 11 | 0 |
AMBRA1_ENST00000458649 | AMBRA1 | Q9C0C7 | Activating molecule in BECN1-regulated autophagy protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 173 | 788 | 103 | 103 | 0 |
AMFR | AMFR | Q9UKV5 | E3 ubiquitin-protein ligase AMFR | chr16 | Not Cancer Driver | No | 1 | hippie | 73 | 229 | 30 | 30 | 0 |
ANLN | ANLN | Q9NQW6 | Anillin | chr7 | Not Cancer Driver | No | 1 | hippie | 144 | 767 | 104 | 104 | 2 |
APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
ATXN3 | ATXN3 | P54252 | Ataxin-3 | chr14 | Not Cancer Driver | No | 1 | hippie | 46 | 181 | 24 | 24 | 0 |
AURKA_ENST00000395915 | AURKA | O14965 | Aurora kinase A | chr20 | Not Cancer Driver | No | 1 | hippie | 36 | 178 | 21 | 21 | 0 |
AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 63 | 8 | 8 | 0 |
BAG1 | BAG1 | Q99933 | BAG family molecular chaperone regulator 1 | chr9 | Not Cancer Driver | No | 1 | biogrid | 29 | 195 | 9 | 9 | 0 |
BAG3 | BAG3 | O95817 | BAG family molecular chaperone regulator 3 | chr10 | Not Cancer Driver | No | 1 | hippie | 57 | 571 | 57 | 57 | 7 |
BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
CAMK1 | CAMK1 | Q14012 | Calcium/calmodulin-dependent protein kinase type 1 | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 40 | 31 | 1 | 1 | 0 |
CAND1 | CAND1 | Q86VP6 | Cullin-associated NEDD8-dissociated protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 161 | 88 | 7 | 7 | 0 |
CAST_ENST00000395813 | CAST | P20810 | Calpastatin | chr5 | Not Cancer Driver | No | 1 | hippie | 73 | 708 | 73 | 73 | 0 |
CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 221 | 23 | 23 | 3 |
CCR5 | CCR5 | P51681 | C-C chemokine receptor type 5 | chr3 | Not Cancer Driver | No | 1 | hippie | 107 | 0 | 0 | 0 | 0 |
CCT3 | CCT3 | P49368 | T-complex protein 1 subunit gamma | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 95 | 12 | 12 | 0 |
CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 0 |
CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 1 | hippie | 287 | 145 | 18 | 18 | 151 |
CLIC1_ENST00000375779 | CLIC1 | O00299 | Chloride intracellular channel protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 27 | 5 | 5 | 0 |
CLIC4 | CLIC4 | Q9Y696 | Chloride intracellular channel protein 4 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 49 | 4 | 4 | 0 |
CLNS1A_ENST00000528364 | CLNS1A | P54105 | Methylosome subunit pICln | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 170 | 13 | 13 | 0 |
CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | Census, Compendium | Yes | 1 | hippie | 415 | 288 | 301 | 301 | 14 |
CUL1_ENST00000602748 | CUL1 | Q13616 | Cullin-1 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 151 | 65 | 9 | 9 | 0 |
CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | Census, Compendium | Yes | 1 | intact, hippie | 123 | 167 | 23 | 23 | 3 |
CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | Not Cancer Driver | No | 1 | hippie | 188 | 372 | 41 | 41 | 3 |
DCTN2_ENST00000548249 | DCTN2 | Q13561 | Dynactin subunit 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 253 | 32 | 32 | 0 |
DDB2 | DDB2 | Q92466 | DNA damage-binding protein 2 | chr11 | Census, Compendium | Yes | 1 | hippie | 45 | 70 | 5 | 5 | 2 |
DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 34 | 181 | 23 | 23 | 0 |
DDX23 | DDX23 | Q9BUQ8 | Probable ATP-dependent RNA helicase DDX23 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 121 | 426 | 71 | 71 | 0 |
DESI1 | DESI1 | Q6ICB0 | Desumoylating isopeptidase 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 23 | 34 | 6 | 6 | 0 |
DYNC1I2_ENST00000409773 | DYNC1I2 | Q13409 | Cytoplasmic dynein 1 intermediate chain 2 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 300 | 42 | 42 | 1 |
ECPAS_ENST00000338205 | ECPAS | Q5VYK3 | Proteasome adapter and scaffold protein ECM29 | chr9 | Not Cancer Driver | No | 1 | hippie | 176 | 240 | 22 | 22 | 0 |
ECT2L | ECT2L | Q008S8 | Epithelial cell-transforming sequence 2 oncogene-like | chr6 | Census | Yes | 1 | hippie, biogrid | 131 | 31 | 7 | 7 | 0 |
EFTUD2 | EFTUD2 | Q15029 | 116 kDa U5 small nuclear ribonucleoprotein component | chr17 | Compendium | Yes | 1 | hippie | 132 | 179 | 30 | 30 | 3 |
EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
EPB41L1 | EPB41L1 | Q9H4G0 | Band 4.1-like protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 151 | 577 | 109 | 109 | 1 |
ERBB3 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | Census, Compendium | Yes | 1 | hippie | 298 | 396 | 70 | 70 | 3 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
EXOSC4 | EXOSC4 | Q9NPD3 | Exosome complex component RRP41 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 23 | 0 | 0 | 0 |
EXOSC5 | EXOSC5 | Q9NQT4 | Exosome complex component RRP46 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 31 | 3 | 3 | 0 |
EXOSC6 | EXOSC6 | Q5RKV6 | Exosome complex component MTR3 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 3 | 102 | 0 | 0 | 0 |
EXOSC9_ENST00000243498 | EXOSC9 | Q06265 | Exosome complex component RRP45 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 154 | 18 | 18 | 1 |
FANCA | FANCA | O15360 | Fanconi anemia group A protein | chr16 | Census, Compendium | Yes | 1 | hippie | 160 | 154 | 15 | 15 | 27 |
FBXO7 | FBXO7 | Q9Y3I1 | F-box only protein 7 | chr22 | Not Cancer Driver | No | 2 | hippie, biogrid | 75 | 243 | 38 | 38 | 1 |
FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | Census, Compendium | Yes | 1 | hippie | 322 | 230 | 38 | 38 | 0 |
FGF11 | FGF11 | Q92914 | Fibroblast growth factor 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 20 | 68 | 5 | 5 | 0 |
FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie | 71 | 160 | 25 | 25 | 0 |
FN1 | FN1 | P02751 | Fibronectin | chr2 | Compendium | Yes | 1 | intact, hippie | 394 | 1243 | 185 | 185 | 8 |
FOXP3 | FOXP3 | Q9BZS1 | Forkhead box protein P3 | chrX | Not Cancer Driver | No | 1 | hippie | 38 | 186 | 16 | 16 | 10 |
FOXR2 | FOXR2 | Q6PJQ5 | Forkhead box protein R2 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 79 | 128 | 41 | 41 | 0 |
FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
GAK | GAK | O14976 | Cyclin-G-associated kinase | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 146 | 589 | 79 | 79 | 0 |
HDAC5_ENST00000586802 | HDAC5 | Q9UQL6 | Histone deacetylase 5 | chr17 | Not Cancer Driver | No | 1 | hippie | 118 | 718 | 73 | 73 | 0 |
HEATR1 | HEATR1 | Q9H583 | HEAT repeat-containing protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 291 | 43 | 5 | 5 | 0 |
HNRNPA2B1 | HNRNPA2B1 | P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 | chr7 | Census, Compendium | Yes | 1 | hippie | 68 | 255 | 41 | 41 | 0 |
HTT | HTT | P42858 | Huntingtin | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 336 | 666 | 69 | 69 | 2 |
HUWE1_ENST00000262854 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | Not Cancer Driver | No | 1 | hippie | 669 | 2091 | 329 | 329 | 21 |
IFITM3 | IFITM3 | Q01628 | Interferon-induced transmembrane protein 3 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 69 | 18 | 5 | 5 | 0 |
IQCB1 | IQCB1 | Q15051 | IQ calmodulin-binding motif-containing protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 72 | 88 | 8 | 8 | 0 |
IRF3_ENST00000597198 | IRF3 | Q14653 | Interferon regulatory factor 3 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 204 | 21 | 21 | 1 |
KIF5B | KIF5B | P33176 | Kinesin-1 heavy chain | chr10 | Census, Compendium | Yes | 1 | hippie | 122 | 586 | 67 | 67 | 0 |
KLF15 | KLF15 | Q9UIH9 | Krueppel-like factor 15 | chr3 | Not Cancer Driver | No | 1 | hippie | 66 | 273 | 48 | 48 | 0 |
KLF16 | KLF16 | Q9BXK1 | Krueppel-like factor 16 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 13 | 204 | 8 | 8 | 0 |
KLF8 | KLF8 | O95600 | Krueppel-like factor 8 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 71 | 270 | 53 | 53 | 0 |
L3MBTL1 | L3MBTL1 | Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 116 | 447 | 40 | 40 | 0 |
L3MBTL4 | L3MBTL4 | Q8NA19 | Lethal(3)malignant brain tumor-like protein 4 | chr18 | Not Cancer Driver | No | 1 | intact, hippie | 125 | 161 | 32 | 32 | 0 |
MAF_ENST00000393350 | MAF | O75444 | Transcription factor Maf | chr16 | Census, Compendium | Yes | 1 | hippie | 39 | 331 | 37 | 37 | 11 |
MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
MEPCE | MEPCE | Q7L2J0 | 7SK snRNA methylphosphate capping enzyme | chr7 | Not Cancer Driver | No | 1 | hippie | 76 | 446 | 42 | 42 | 0 |
MESD_ENST00000561312 | MESD | Q14696 | LRP chaperone MESD | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 21 | 150 | 14 | 14 | 0 |
MFN2_ENST00000444836 | MFN2 | O95140 | Mitofusin-2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 81 | 9 | 9 | 20 |
MRPS16 | MRPS16 | Q9Y3D3 | 28S ribosomal protein S16, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 29 | 2 | 2 | 0 |
MRPS7 | MRPS7 | Q9Y2R9 | 28S ribosomal protein S7, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 26 | 0 | 0 | 1 |
MRPS9 | MRPS9 | P82933 | 28S ribosomal protein S9, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 75 | 9 | 9 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
NEDD8 | NEDD8 | Q15843 | NEDD8 | chr14 | Not Cancer Driver | No | 1 | hippie | 10 | 36 | 5 | 5 | 0 |
NELFE | NELFE | P18615 | Negative elongation factor E | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 352 | 45 | 45 | 0 |
NEURL4 | NEURL4 | Q96JN8 | Neuralized-like protein 4 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 217 | 751 | 119 | 119 | 0 |
NFKBIE | NFKBIE | O00221 | NF-kappa-B inhibitor epsilon | chr6 | Census, Compendium | Yes | 1 | hippie | 41 | 284 | 16 | 16 | 0 |
NFX1 | NFX1 | Q12986 | Transcriptional repressor NF-X1 | chr9 | Not Cancer Driver | No | 1 | hippie | 121 | 491 | 46 | 46 | 0 |
NHLRC2 | NHLRC2 | Q8NBF2 | NHL repeat-containing protein 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 74 | 103 | 12 | 12 | 0 |
NOS2 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | Not Cancer Driver | No | 1 | hippie | 207 | 201 | 33 | 33 | 0 |
NPC1 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 155 | 24 | 0 | 0 | 150 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NUP98_ENST00000359171 | NUP98 | P52948 | Nuclear pore complex protein Nup98-Nup96 | chr11 | Census | Yes | 1 | hippie | 227 | 1008 | 107 | 107 | 0 |
OXSR1 | OXSR1 | O95747 | Serine/threonine-protein kinase OSR1 | chr3 | Not Cancer Driver | No | 1 | hippie | 69 | 208 | 29 | 29 | 0 |
PCBP3 | PCBP3 | P57721 | Poly(rC)-binding protein 3 | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 230 | 48 | 48 | 0 |
PCK1 | PCK1 | P35558 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | chr20 | Not Cancer Driver | No | 1 | hippie | 142 | 110 | 28 | 28 | 1 |
PCLAF | PCLAF | Q15004 | PCNA-associated factor | chr15 | Not Cancer Driver | No | 1 | hippie | 20 | 111 | 20 | 20 | 0 |
PEX19 | PEX19 | P40855 | Peroxisomal biogenesis factor 19 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 266 | 38 | 38 | 0 |
PHKG2 | PHKG2 | P15735 | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | chr16 | Not Cancer Driver | No | 1 | hippie | 48 | 50 | 6 | 6 | 4 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PLK1 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | Not Cancer Driver | No | 1 | hippie | 87 | 119 | 13 | 13 | 0 |
POLR2A | POLR2A | P24928-2 | Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 | chr17 | Census | Yes | 1 | hippie, biogrid | 56 | 230 | 20 | 20 | 0 |
POMP | POMP | Q9Y244 | Proteasome maturation protein | chr13 | Not Cancer Driver | No | 3 | hippie, biogrid | 16 | 41 | 7 | 7 | 0 |
PPL | PPL | O60437 | Periplakin | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 219 | 1133 | 133 | 133 | 0 |
PPP6C_ENST00000373547 | PPP6C | O00743 | Serine/threonine-protein phosphatase 6 catalytic subunit | chr9 | Census, Compendium | Yes | 1 | hippie | 63 | 0 | 0 | 0 | 0 |
PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 2 | intact, hippie | 110 | 78 | 15 | 15 | 31 |
PRNP | PRNP | P04156 | Major prion protein | chr20 | Not Cancer Driver | No | 1 | hippie | 36 | 115 | 7 | 7 | 18 |
PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | Not Cancer Driver | No | 2 | intact, hippie | 61 | 134 | 21 | 21 | 96 |
PSMA1_ENST00000396394 | PSMA1 | P25786 | Proteasome subunit alpha type-1 | chr11 | Not Cancer Driver | No | 10 | intact, hippie, biogrid | 48 | 51 | 9 | 9 | 0 |
PSMA2 | PSMA2 | P25787 | Proteasome subunit alpha type-2 | chr7 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 20 | 0 | 0 | 0 | 0 |
PSMA3 | PSMA3 | P25788 | Proteasome subunit alpha type-3 | chr14 | Not Cancer Driver | No | 4 | hippie, biogrid | 27 | 30 | 5 | 5 | 0 |
PSMA4_ENST00000559082 | PSMA4 | P25789 | Proteasome subunit alpha type-4 | chr15 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 29 | 28 | 9 | 9 | 0 |
PSMA5 | PSMA5 | P28066 | Proteasome subunit alpha type-5 | chr1 | Not Cancer Driver | No | 1 | hippie | 24 | 23 | 1 | 1 | 0 |
PSMA6 | PSMA6 | P60900 | Proteasome subunit alpha type-6 | chr14 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 37 | 2 | 1 | 1 | 0 |
PSMA7 | PSMA7 | O14818 | Proteasome subunit alpha type-7 | chr20 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 24 | 23 | 1 | 1 | 0 |
PSMA8 | PSMA8 | Q8TAA3 | Proteasome subunit alpha-type 8 | chr18 | Not Cancer Driver | No | 3 | hippie, biogrid | 42 | 15 | 5 | 5 | 0 |
PSMB1 | PSMB1 | P20618 | Proteasome subunit beta type-1 | chr6 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 25 | 14 | 2 | 2 | 0 |
PSMB10 | PSMB10 | P40306 | Proteasome subunit beta type-10 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 36 | 5 | 5 | 0 |
PSMB2 | PSMB2 | P49721 | Proteasome subunit beta type-2 | chr1 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
PSMB4 | PSMB4 | P28070 | Proteasome subunit beta type-4 | chr1 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 23 | 18 | 2 | 2 | 0 |
PSMB5 | PSMB5 | P28074 | Proteasome subunit beta type-5 | chr14 | Not Cancer Driver | No | 4 | hippie, biogrid | 39 | 9 | 0 | 0 | 0 |
PSMB6 | PSMB6 | P28072 | Proteasome subunit beta type-6 | chr17 | Not Cancer Driver | No | 4 | hippie, biogrid | 19 | 22 | 1 | 1 | 0 |
PSMB7 | PSMB7 | Q99436 | Proteasome subunit beta type-7 | chr9 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 25 | 26 | 3 | 3 | 0 |
PSMB8 | PSMB8 | P28062 | Proteasome subunit beta type-8 | chr6 | Not Cancer Driver | No | 3 | hippie, biogrid | 43 | 62 | 7 | 7 | 3 |
PSMB9 | PSMB9 | P28065 | Proteasome subunit beta type-9 | chr6 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 21 | 17 | 1 | 1 | 1 |
PSMC1 | PSMC1 | P62191 | 26S proteasome regulatory subunit 4 | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 36 | 165 | 10 | 10 | 0 |
PSMC2_ENST00000292644 | PSMC2 | P35998 | 26S proteasome regulatory subunit 7 | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 63 | 120 | 13 | 13 | 0 |
PSMC3_ENST00000298852 | PSMC3 | P17980 | 26S proteasome regulatory subunit 6A | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 55 | 131 | 10 | 10 | 0 |
PSMC4 | PSMC4 | P43686 | 26S proteasome regulatory subunit 6B | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 51 | 21 | 3 | 3 | 0 |
PSMC5 | PSMC5 | P62195 | 26S proteasome regulatory subunit 8 | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 52 | 64 | 6 | 6 | 0 |
PSMC6_ENST00000606149 | PSMC6 | P62333 | 26S proteasome regulatory subunit 10B | chr14 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 49 | 69 | 8 | 8 | 0 |
PSMD1 | PSMD1 | Q99460 | 26S proteasome non-ATPase regulatory subunit 1 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 110 | 201 | 19 | 19 | 0 |
PSMD11_ENST00000457654 | PSMD11 | O00231 | 26S proteasome non-ATPase regulatory subunit 11 | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 51 | 0 | 0 | 0 | 0 |
PSMD12 | PSMD12 | O00232 | 26S proteasome non-ATPase regulatory subunit 12 | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 48 | 24 | 3 | 3 | 0 |
PSMD13_ENST00000532097 | PSMD13 | Q9UNM6 | 26S proteasome non-ATPase regulatory subunit 13 | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 30 | 13 | 3 | 3 | 0 |
PSMD14 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 23 | 67 | 6 | 6 | 0 |
PSMD2 | PSMD2 | Q13200 | 26S proteasome non-ATPase regulatory subunit 2 | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 100 | 135 | 14 | 14 | 0 |
PSMD3 | PSMD3 | O43242 | 26S proteasome non-ATPase regulatory subunit 3 | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 69 | 152 | 19 | 19 | 0 |
PSMD4_ENST00000368884 | PSMD4 | P55036 | 26S proteasome non-ATPase regulatory subunit 4 | chr1 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 43 | 243 | 25 | 25 | 0 |
PSMD5 | PSMD5 | Q16401 | 26S proteasome non-ATPase regulatory subunit 5 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 2 | 1 | 1 | 0 |
PSMD6_ENST00000295901 | PSMD6 | Q15008 | 26S proteasome non-ATPase regulatory subunit 6 | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 33 | 40 | 3 | 3 | 0 |
PSMD7 | PSMD7 | P51665 | 26S proteasome non-ATPase regulatory subunit 7 | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 39 | 70 | 4 | 4 | 0 |
PSMD8 | PSMD8 | P48556 | 26S proteasome non-ATPase regulatory subunit 8 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 20 | 78 | 2 | 2 | 0 |
PSME1_ENST00000206451 | PSME1 | Q06323 | Proteasome activator complex subunit 1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 80 | 8 | 8 | 0 |
PSME2 | PSME2 | Q9UL46 | Proteasome activator complex subunit 2 | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 32 | 39 | 3 | 3 | 0 |
PSME3_ENST00000590720 | PSME3 | P61289 | Proteasome activator complex subunit 3 | chr17 | Not Cancer Driver | No | 3 | hippie, biogrid | 20 | 25 | 5 | 5 | 0 |
PSME4 | PSME4 | Q14997 | Proteasome activator complex subunit 4 | chr2 | Not Cancer Driver | No | 3 | hippie, biogrid | 214 | 134 | 12 | 12 | 0 |
PSMF1_ENST00000333082 | PSMF1 | Q92530 | Proteasome inhibitor PI31 subunit | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 140 | 26 | 26 | 0 |
PSMG1 | PSMG1 | O95456 | Proteasome assembly chaperone 1 | chr21 | Not Cancer Driver | No | 2 | hippie, biogrid | 31 | 25 | 1 | 1 | 0 |
PSMG2 | PSMG2 | Q969U7 | Proteasome assembly chaperone 2 | chr18 | Not Cancer Driver | No | 3 | hippie, biogrid | 19 | 3 | 0 | 0 | 0 |
PSMG3_ENST00000252329 | PSMG3 | Q9BT73 | Proteasome assembly chaperone 3 | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 18 | 1 | 0 | 0 | 0 |
PSMG4_ENST00000438998 | PSMG4 | Q5JS54 | Proteasome assembly chaperone 4 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 4 | 9 | 4 | 4 | 0 |
PTPN2 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | Not Cancer Driver | No | 1 | hippie | 57 | 120 | 14 | 14 | 0 |
RAD23A | RAD23A | P54725 | UV excision repair protein RAD23 homolog A | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 283 | 41 | 41 | 0 |
RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 202 | 578 | 75 | 75 | 0 |
RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
RIPK1_ENST00000380409 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | Compendium | Yes | 1 | intact, hippie, biogrid | 82 | 277 | 39 | 39 | 4 |
RNF185 | RNF185 | Q96GF1 | E3 ubiquitin-protein ligase RNF185 | chr22 | Not Cancer Driver | No | 1 | hippie | 25 | 82 | 15 | 15 | 0 |
RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
RPP38_ENST00000378202 | RPP38 | P78345 | Ribonuclease P protein subunit p38 | chr10 | Not Cancer Driver | No | 1 | hippie | 36 | 118 | 19 | 19 | 0 |
RRP1B | RRP1B | Q14684 | Ribosomal RNA processing protein 1 homolog B | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 74 | 513 | 48 | 48 | 0 |
S100A9 | S100A9 | P06702 | Protein S100-A9 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 76 | 7 | 7 | 0 |
SART3 | SART3 | Q15020 | Squamous cell carcinoma antigen recognized by T-cells 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 101 | 404 | 45 | 45 | 0 |
SEC24C | SEC24C | P53992 | Protein transport protein Sec24C | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 121 | 402 | 38 | 38 | 0 |
SF3A1 | SF3A1 | Q15459 | Splicing factor 3A subunit 1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 631 | 67 | 67 | 0 |
SH3BGRL | SH3BGRL | O75368 | SH3 domain-binding glutamic acid-rich-like protein | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 51 | 8 | 8 | 0 |
SKP1_ENST00000517625 | SKP1 | P63208 | S-phase kinase-associated protein 1 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 19 | 95 | 17 | 17 | 0 |
SLC16A11 | SLC16A11 | Q8NCK7 | Monocarboxylate transporter 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 33 | 72 | 5 | 5 | 0 |
SLX1A_ENST00000345535 | SLX1A | Q9BQ83-2 | Isoform 2 of Structure-specific endonuclease subunit SLX1 | chr16 | Not Cancer Driver | No | 1 | hippie | 5 | 27 | 0 | 0 | 0 |
SLX1B | SLX1B | Q9BQ83 | Structure-specific endonuclease subunit SLX1 | chr16 | Not Cancer Driver | No | 1 | biogrid | 3 | 80 | 1 | 1 | 0 |
SMURF1 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | Not Cancer Driver | No | 1 | biogrid | 89 | 256 | 31 | 31 | 0 |
SNRPA1 | SNRPA1 | P09661 | U2 small nuclear ribonucleoprotein A' | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 93 | 14 | 14 | 0 |
SPRTN | SPRTN | Q9H040 | DNA-dependent metalloprotease SPRTN | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 252 | 38 | 38 | 1 |
SRSF2 | SRSF2 | Q01130 | Serine/arginine-rich splicing factor 2 | chr17 | Census, Compendium | Yes | 1 | hippie, biogrid | 38 | 219 | 38 | 38 | 0 |
SRXN1 | SRXN1 | Q9BYN0 | Sulfiredoxin-1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 48 | 2 | 2 | 0 |
STK24 | STK24 | Q9Y6E0 | Serine/threonine-protein kinase 24 | chr13 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 67 | 118 | 16 | 16 | 0 |
STK25 | STK25 | O00506 | Serine/threonine-protein kinase 25 | chr2 | Not Cancer Driver | No | 1 | hippie | 42 | 170 | 15 | 15 | 0 |
STK3_ENST00000419617 | STK3 | Q13188 | Serine/threonine-protein kinase 3 | chr8 | Not Cancer Driver | No | 1 | hippie | 70 | 241 | 32 | 32 | 0 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
SYAP1 | SYAP1 | Q96A49 | Synapse-associated protein 1 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 221 | 22 | 22 | 0 |
SYVN1 | SYVN1 | Q86TM6 | E3 ubiquitin-protein ligase synoviolin | chr11 | Not Cancer Driver | No | 1 | hippie | 63 | 284 | 32 | 32 | 0 |
TEX101_ENST00000598265 | TEX101 | Q9BY14 | Testis-expressed protein 101 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 45 | 2 | 0 | 0 | 0 |
TJP1_ENST00000346128 | TJP1 | Q07157 | Tight junction protein ZO-1 | chr15 | Not Cancer Driver | No | 1 | hippie | 198 | 1350 | 151 | 151 | 0 |
TLX2 | TLX2 | O43763 | T-cell leukemia homeobox protein 2 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 220 | 15 | 15 | 0 |
TNIP2 | TNIP2 | Q8NFZ5 | TNFAIP3-interacting protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 43 | 316 | 36 | 36 | 0 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TXNIP | TXNIP | Q9H3M7 | Thioredoxin-interacting protein | chr1 | Not Cancer Driver | No | 1 | hippie | 61 | 77 | 14 | 14 | 0 |
TYMS | TYMS | P04818 | Thymidylate synthase | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 41 | 0 | 0 | 0 |
U2AF2 | U2AF2 | P26368 | Splicing factor U2AF 65 kDa subunit | chr19 | Compendium | Yes | 1 | hippie, biogrid | 78 | 191 | 28 | 28 | 0 |
UBA2 | UBA2 | Q9UBT2 | SUMO-activating enzyme subunit 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 219 | 33 | 33 | 0 |
UBE2C | UBE2C | O00762 | Ubiquitin-conjugating enzyme E2 C | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 40 | 0 | 0 | 0 |
UBE2L3_ENST00000342192 | UBE2L3 | P68036 | Ubiquitin-conjugating enzyme E2 L3 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 32 | 4 | 4 | 0 |
UBE2M | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 32 | 6 | 6 | 0 |
UBE3A | UBE3A | Q05086 | Ubiquitin-protein ligase E3A | chr15 | Not Cancer Driver | No | 1 | hippie | 141 | 136 | 22 | 22 | 0 |
UBQLN1 | UBQLN1 | Q9UMX0 | Ubiquilin-1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 543 | 58 | 58 | 0 |
UBQLN2 | UBQLN2 | Q9UHD9 | Ubiquilin-2 | chrX | Not Cancer Driver | No | 1 | hippie | 82 | 581 | 79 | 79 | 8 |
UBQLN4 | UBQLN4 | Q9NRR5 | Ubiquilin-4 | chr1 | Not Cancer Driver | No | 1 | hippie | 70 | 561 | 67 | 67 | 1 |
UCHL5 | UCHL5 | Q9Y5K5 | Ubiquitin carboxyl-terminal hydrolase isozyme L5 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 33 | 41 | 7 | 7 | 0 |
UNKL_ENST00000389221 | UNKL | Q9H9P5 | Putative E3 ubiquitin-protein ligase UNKL | chr16 | Not Cancer Driver | No | 1 | hippie | 59 | 415 | 28 | 28 | 0 |
USP14 | USP14 | P54578 | Ubiquitin carboxyl-terminal hydrolase 14 | chr18 | Not Cancer Driver | No | 1 | hippie | 59 | 86 | 6 | 6 | 0 |
USP7 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | Not Cancer Driver | No | 1 | hippie | 170 | 215 | 45 | 45 | 0 |
VASP | VASP | P50552 | Vasodilator-stimulated phosphoprotein | chr19 | Not Cancer Driver | No | 1 | hippie | 39 | 335 | 34 | 34 | 0 |
VCAM1 | VCAM1 | P19320 | Vascular cell adhesion protein 1 | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 188 | 110 | 28 | 28 | 0 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
WFS1_ENST00000503569 | WFS1 | O76024 | Wolframin | chr4 | Not Cancer Driver | No | 1 | hippie | 105 | 203 | 10 | 10 | 39 |
XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 19 | 169 | 9 | 9 | 0 |
YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | Not Cancer Driver | No | 1 | hippie | 51 | 489 | 49 | 49 | 0 |
YWHAZ_ENST00000395956 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | hippie | 30 | 81 | 10 | 10 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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