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PROX1 ,PROX1 ,Q92786
  • Uniprot Accession= Q92786
  • Ensembl Transcript= ENST00000366958.8
  • Uniprot Name= PROX1
  • Name= Prospero homeobox protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 12
  • Number of Interaction partner in biogrid: 6
  • Number of Interaction partner in hippie: 39
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
BRD3 BRD3 Q15059 Bromodomain-containing protein 3 chr9 Census Yes 1 hippie 87 566 68 68 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRPF3 BRPF3 Q9ULD4 Bromodomain and PHD finger-containing protein 3 chr6 Not Cancer Driver No 1 hippie 143 633 74 74 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
CCL26_ENST00000005180 CCL26 Q9Y258 C-C motif chemokine 26 chr7 Not Cancer Driver No 1 intact 9 0 0 0 0
CEBPZ CEBPZ Q03701 CCAAT/enhancer-binding protein zeta chr2 Not Cancer Driver No 1 hippie 95 488 44 44 0
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 hippie 419 974 177 177 6
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 42 123 9 9 1
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 1 intact, hippie 48 94 4 4 0
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 Not Cancer Driver No 1 intact 109 48 8 8 0
CYTH4 CYTH4 Q9UIA0 Cytohesin-4 chr22 Not Cancer Driver No 1 hippie, biogrid 70 52 10 10 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ESRRA_ENST00000000442 ESRRA P11474 Steroid hormone receptor ERR1 chr11 Compendium Yes 1 hippie 37 101 9 9 0
ESRRG_ENST00000408911 ESRRG P62508 Estrogen-related receptor gamma chr1 Not Cancer Driver No 2 hippie, biogrid 135 76 29 29 0
FGF11 FGF11 Q92914 Fibroblast growth factor 11 chr17 Not Cancer Driver No 1 hippie 20 68 5 5 0
GIT2 GIT2 Q14161 ARF GTPase-activating protein GIT2 chr12 Not Cancer Driver No 1 hippie 83 492 47 47 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 intact, hippie 46 145 14 14 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 1 intact, hippie 65 61 8 8 0
HNF1A_ENST00000257555 HNF1A P20823 Hepatocyte nuclear factor 1-alpha chr12 Census, Compendium Yes 1 hippie 96 569 80 80 42
HNF4A HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 Not Cancer Driver No 1 hippie 135 127 48 48 5
IL18 IL18 Q14116 Interleukin-18 chr11 Not Cancer Driver No 1 intact 19 16 3 3 0
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 Census, Compendium Yes 1 hippie 99 155 45 45 0
LBH LBH Q53QV2 Protein LBH chr2 Not Cancer Driver No 1 intact, hippie 15 72 10 10 0
MBD3L2 MBD3L2 Q8NHZ7 Methyl-CpG-binding domain protein 3-like 2 chr19 Not Cancer Driver No 1 hippie, biogrid 7 188 7 7 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 45 145 16 16 0
NR3C2_ENST00000344721 NR3C2 P08235 Mineralocorticoid receptor chr4 Not Cancer Driver No 1 hippie 168 484 88 88 14
NR5A1 NR5A1 Q13285 Steroidogenic factor 1 chr9 Not Cancer Driver No 1 hippie 60 133 29 29 24
NR5A2 NR5A2 O00482 Nuclear receptor subfamily 5 group A member 2 chr1 Not Cancer Driver No 1 hippie 126 154 35 35 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 Not Cancer Driver No 1 hippie 72 337 56 56 38
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 Not Cancer Driver No 1 hippie 72 69 7 7 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 72 44 4 4 3
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 Not Cancer Driver No 1 hippie 182 537 141 141 0
RBBP4 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 Not Cancer Driver No 1 hippie, biogrid 53 169 23 23 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 Not Cancer Driver No 1 hippie 57 182 17 17 4
S100A2_ENST00000368709 S100A2 P29034 Protein S100-A2 chr1 Not Cancer Driver No 1 hippie, biogrid 16 6 2 2 0
S100P S100P P25815 Protein S100-P chr4 Not Cancer Driver No 1 hippie, biogrid 7 3 1 1 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 intact, hippie 97 111 19 19 5
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 intact, hippie 10 76 7 7 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 Not Cancer Driver No 1 intact 28 1 0 0 0
TRIM66_ENST00000299550 TRIM66 O15016 Tripartite motif-containing protein 66 chr11 Not Cancer Driver No 1 hippie 58 723 32 32 0
ZBTB3 ZBTB3 Q9H5J0 Zinc finger and BTB domain-containing protein 3 chr11 Not Cancer Driver No 1 intact, hippie 68 352 35 35 0