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PRMT6 ,PRMT6 ,Q96LA8
  • Uniprot Accession= Q96LA8
  • Ensembl Transcript= ENST00000370078.1
  • Uniprot Name= PRMT6
  • Name= Protein arginine N-methyltransferase 6
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 44
  • Number of Interaction partner in hippie: 138
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AK8 AK8 Q96MA6 Adenylate kinase 8 chr9 Not Cancer Driver No 1 hippie 74 53 8 8 0
AKT3_ENST00000366539 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 Census, Compendium Yes 2 hippie, biogrid 92 131 24 24 3
AP1G2_ENST00000397120 AP1G2 O75843 AP-1 complex subunit gamma-like 2 chr14 Not Cancer Driver No 1 hippie 108 110 10 10 0
ARFGEF2 ARFGEF2 Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 chr20 Not Cancer Driver No 1 hippie, biogrid 254 358 63 63 0
ASB3 ASB3 Q9Y575 Ankyrin repeat and SOCS box protein 3 chr2 Not Cancer Driver No 1 hippie 71 0 0 0 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie, biogrid 200 115 29 29 31
AUNIP_ENST00000374298 AUNIP Q9H7T9 Aurora kinase A and ninein-interacting protein chr1 Not Cancer Driver No 1 hippie 23 341 21 21 0
BCAT1_ENST00000261192 BCAT1 P54687 Branched-chain-amino-acid aminotransferase, cytosolic chr12 Not Cancer Driver No 1 hippie 67 8 2 2 0
BEX1 BEX1 Q9HBH7 Protein BEX1 chrX Not Cancer Driver No 1 hippie, biogrid 26 113 24 24 0
BEX2_ENST00000372677 BEX2 Q9BXY8 Protein BEX2 chrX Not Cancer Driver No 1 hippie, biogrid 23 105 13 13 0
BLZF1 BLZF1 Q9H2G9 Golgin-45 chr1 Not Cancer Driver No 1 hippie 51 218 24 24 0
BMP3 BMP3 P12645 Bone morphogenetic protein 3 chr4 Not Cancer Driver No 1 hippie 120 147 48 48 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
C8orf74 C8orf74 Q6P047 Uncharacterized protein C8orf74 chr8 Not Cancer Driver No 1 hippie 48 53 14 14 0
CDCA4 CDCA4 Q9BXL8 Cell division cycle-associated protein 4 chr14 Not Cancer Driver No 1 hippie 36 138 18 18 0
CETN2 CETN2 P41208 Centrin-2 chrX Not Cancer Driver No 1 hippie 33 97 11 11 0
CIRBP_ENST00000586472 CIRBP Q14011 Cold-inducible RNA-binding protein chr19 Not Cancer Driver No 2 hippie, biogrid 19 129 13 13 0
CMTM8 CMTM8 Q8IZV2 CKLF-like MARVEL transmembrane domain-containing protein 8 chr3 Not Cancer Driver No 1 hippie, biogrid 23 9 1 1 0
DCAF16 DCAF16 Q9NXF7 DDB1- and CUL4-associated factor 16 chr4 Not Cancer Driver No 1 hippie 30 67 9 9 0
DDX23 DDX23 Q9BUQ8 Probable ATP-dependent RNA helicase DDX23 chr12 Not Cancer Driver No 3 hippie, biogrid 121 426 71 71 0
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 hippie 50 152 21 21 0
DNAJC12 DNAJC12 Q9UKB3 DnaJ homolog subfamily C member 12 chr10 Not Cancer Driver No 3 hippie, biogrid 29 124 17 17 1
DNALI1 DNALI1 A0A499FIY3 Axonemal dynein light intermediate polypeptide 1 chr1 Not Cancer Driver No 1 hippie 28 192 16 16 0
DXO_ENST00000375356 DXO O77932 Decapping and exoribonuclease protein chr6 Not Cancer Driver No 1 hippie 46 143 17 17 0
DYNC2LI1_ENST00000260605 DYNC2LI1 Q8TCX1 Cytoplasmic dynein 2 light intermediate chain 1 chr2 Not Cancer Driver No 1 hippie, biogrid 53 93 8 8 2
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ENAH ENAH Q8N8S7 Protein enabled homolog chr1 Not Cancer Driver No 3 hippie, biogrid 65 514 61 61 0
FAM19A3_ENST00000361886 TAFA3 Q7Z5A8 Chemokine-like protein TAFA-3 chr1 Not Cancer Driver No 1 hippie 17 6 0 0 0
FBL FBL P22087 rRNA 2'-O-methyltransferase fibrillarin chr19 Not Cancer Driver No 1 hippie 46 145 22 22 0
FBXO24_ENST00000241071 FBXO24 O75426 F-box only protein 24 chr7 Not Cancer Driver No 1 hippie 119 55 10 10 0
FIP1L1 FIP1L1 Q6UN15 Pre-mRNA 3'-end-processing factor FIP1 chr4 Census Yes 1 hippie 88 572 85 85 0
FKBP7 FKBP7 Q9Y680 Peptidyl-prolyl cis-trans isomerase FKBP7 chr2 Not Cancer Driver No 1 hippie 28 52 9 9 0
FOSL2 FOSL2 P15408 Fos-related antigen 2 chr2 Not Cancer Driver No 1 hippie, biogrid 54 323 54 54 0
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 Census, Compendium Yes 1 hippie 100 295 53 53 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 Not Cancer Driver No 1 hippie, biogrid 33 411 24 24 32
FYCO1 FYCO1 Q9BQS8 FYVE and coiled-coil domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 181 892 106 106 1
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GBE1 GBE1 Q04446 1,4-alpha-glucan-branching enzyme chr3 Not Cancer Driver No 1 hippie 101 8 0 0 9
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 Not Cancer Driver No 1 hippie 29 319 26 26 0
GRHL3 GRHL3 Q8TE85 Grainyhead-like protein 3 homolog chr1 Not Cancer Driver No 1 hippie 83 291 38 38 3
GSTCD_ENST00000394728 GSTCD Q8NEC7 Glutathione S-transferase C-terminal domain-containing protein chr4 Not Cancer Driver No 1 hippie 70 105 9 9 0
GTPBP2 GTPBP2 Q9BX10 GTP-binding protein 2 chr6 Not Cancer Driver No 1 hippie 53 89 5 5 0
HESX1 HESX1 Q9UBX0 Homeobox expressed in ES cells 1 chr3 Not Cancer Driver No 1 hippie 32 59 9 9 6
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HMGA1 HMGA1 P17096 High mobility group protein HMG-I/HMG-Y chr6 Census Yes 1 hippie 6 107 6 6 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 Census Yes 1 hippie 12 109 12 12 0
HNRNPH2 HNRNPH2 P55795 Heterogeneous nuclear ribonucleoprotein H2 chrX Not Cancer Driver No 1 hippie 73 168 34 34 3
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 Not Cancer Driver No 1 hippie 90 262 68 68 0
HOXA5 HOXA5 P20719 Homeobox protein Hox-A5 chr7 Not Cancer Driver No 1 hippie 43 209 37 37 0
HOXC4 HOXC4 P09017 Homeobox protein Hox-C4 chr12 Not Cancer Driver No 1 hippie 40 227 33 33 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 93 286 38 38 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 Not Cancer Driver No 1 hippie 14 52 7 7 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 Not Cancer Driver No 1 hippie, biogrid 39 44 12 12 0
ILF2 ILF2 Q12905 Interleukin enhancer-binding factor 2 chr1 Not Cancer Driver No 3 hippie, biogrid 36 92 9 9 0
ILF3_ENST00000590261 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 Not Cancer Driver No 1 hippie, biogrid 103 674 82 82 0
IQSEC1_ENST00000273221 IQSEC1 Q6DN90 IQ motif and SEC7 domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 141 610 97 97 2
KIAA0408 KIAA0408 Q6ZU52 Uncharacterized protein KIAA0408 chr6 Not Cancer Driver No 1 hippie 112 607 94 94 0
KIF9_ENST00000452770 KIF9 Q9HAQ2 Kinesin-like protein KIF9 chr3 Not Cancer Driver No 1 hippie 94 213 42 42 0
KIRREL1 KIRREL1 Q96J84 Kin of IRRE-like protein 1 chr1 Not Cancer Driver No 1 hippie 141 273 57 57 1
KLHL20 KLHL20 Q9Y2M5 Kelch-like protein 20 chr1 Not Cancer Driver No 1 hippie 83 143 17 17 0
LDHAL6B LDHAL6B Q9BYZ2 L-lactate dehydrogenase A-like 6B chr15 Not Cancer Driver No 1 hippie 54 17 2 2 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 Census Yes 3 hippie, biogrid 64 370 57 57 0
LENG8 LENG8 Q96PV6 Leukocyte receptor cluster member 8 chr19 Not Cancer Driver No 1 hippie 137 515 97 97 0
LOXL4 LOXL4 Q96JB6 Lysyl oxidase homolog 4 chr10 Not Cancer Driver No 1 hippie 95 122 11 11 0
LRRC40 LRRC40 Q9H9A6 Leucine-rich repeat-containing protein 40 chr1 Not Cancer Driver No 1 hippie, biogrid 76 35 3 3 0
LYPD4 LYPD4 Q6UWN0 Ly6/PLAUR domain-containing protein 4 chr19 Not Cancer Driver No 2 hippie, biogrid 44 0 0 0 0
MADD MADD Q8WXG6 MAP kinase-activating death domain protein chr11 Not Cancer Driver No 2 hippie, biogrid 207 723 81 81 4
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 Census, Compendium Yes 1 hippie 75 139 12 12 1
MED28 MED28 Q9H204 Mediator of RNA polymerase II transcription subunit 28 chr4 Not Cancer Driver No 1 hippie 24 101 18 18 0
METTL27 METTL27 Q8N6F8 Methyltransferase-like protein 27 chr7 Not Cancer Driver No 1 hippie 36 47 8 8 0
MLC1 MLC1 Q15049 Membrane protein MLC1 chr22 Not Cancer Driver No 1 hippie 53 35 7 7 15
MLF1_ENST00000355893 MLF1 P58340 Myeloid leukemia factor 1 chr3 Census Yes 1 hippie, biogrid 40 243 37 37 0
MNDA MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 Not Cancer Driver No 1 hippie 180 172 76 76 0
MROH1 MROH1 Q8NDA8 Maestro heat-like repeat-containing protein family member 1 chr8 Not Cancer Driver No 1 hippie, biogrid 52 67 0 0 0
MRPL38 MRPL38 Q96DV4 39S ribosomal protein L38, mitochondrial chr17 Not Cancer Driver No 3 hippie, biogrid 41 88 13 13 0
MTF2 MTF2 Q9Y483 Metal-response element-binding transcription factor 2 chr1 Not Cancer Driver No 1 hippie 70 225 28 28 0
MTPAP MTPAP Q9NVV4 Poly(A) RNA polymerase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 73 136 22 22 1
N4BP2L2_ENST00000267068 N4BP2L2 Q92802 NEDD4-binding protein 2-like 2 chr13 Not Cancer Driver No 3 hippie, biogrid 81 373 55 55 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 Not Cancer Driver No 1 hippie 92 285 39 39 12
NOSTRIN_ENST00000317647 NOSTRIN Q8IVI9 Nostrin chr2 Not Cancer Driver No 1 hippie 55 190 18 18 0
NR1D2 NR1D2 Q14995 Nuclear receptor subfamily 1 group D member 2 chr3 Not Cancer Driver No 1 hippie 76 223 25 25 0
NRM NRM Q8IXM6 Nurim chr6 Not Cancer Driver No 1 hippie, biogrid 19 1 0 0 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 Not Cancer Driver No 1 hippie 67 71 12 12 0
OPA3_ENST00000263275 OPA3 Q9H6K4 Optic atrophy 3 protein chr19 Not Cancer Driver No 1 hippie 18 44 7 7 2
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 hippie 100 317 55 55 0
PCGF5 PCGF5 Q86SE9 Polycomb group RING finger protein 5 chr10 Not Cancer Driver No 1 hippie 31 52 5 5 0
PELO PELO Q9BRX2 Protein pelota homolog chr5 Not Cancer Driver No 1 hippie 38 67 10 10 0
PEX7 PEX7 O00628 Peroxisomal targeting signal 2 receptor chr6 Not Cancer Driver No 1 hippie 32 0 0 0 2
PGRMC2_ENST00000296425 PGRMC2 O15173 Membrane-associated progesterone receptor component 2 chr4 Not Cancer Driver No 1 hippie, biogrid 16 83 4 4 0
PIAS1_ENST00000249636 PIAS1 O75925 E3 SUMO-protein ligase PIAS1 chr15 Not Cancer Driver No 1 hippie 80 241 43 43 0
PPP1R1A PPP1R1A Q13522 Protein phosphatase 1 regulatory subunit 1A chr12 Not Cancer Driver No 3 hippie, biogrid 24 171 24 24 0
PRMT6 PRMT6 Q96LA8 Protein arginine N-methyltransferase 6 chr1 Not Cancer Driver No 1 hippie 43 71 7 7 0
PSMD11_ENST00000457654 PSMD11 O00231 26S proteasome non-ATPase regulatory subunit 11 chr17 Not Cancer Driver No 1 hippie 51 0 0 0 0
PYCR3_ENST00000495276 PYCR3 Q53H96 Pyrroline-5-carboxylate reductase 3 chr8 Not Cancer Driver No 1 hippie 21 11 0 0 0
PYGO1 PYGO1 Q9Y3Y4 Pygopus homolog 1 chr15 Not Cancer Driver No 1 hippie 71 362 60 60 0
RAB29 RAB29 O14966 Ras-related protein Rab-7L1 chr1 Not Cancer Driver No 1 hippie, biogrid 28 18 3 3 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAD17 RAD17 O75943 Cell cycle checkpoint protein RAD17 chr5 Census Yes 1 hippie 78 207 19 19 0
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 Not Cancer Driver No 1 hippie 90 126 44 44 0
RBM3_ENST00000376755 RBM3 P98179 RNA-binding protein 3 chrX Not Cancer Driver No 1 hippie, biogrid 22 134 18 18 0
SEC23IP SEC23IP Q9Y6Y8 SEC23-interacting protein chr10 Not Cancer Driver No 3 hippie, biogrid 112 371 40 40 0
SERGEF SERGEF Q9UGK8 Secretion-regulating guanine nucleotide exchange factor chr11 Not Cancer Driver No 1 hippie 49 91 7 7 0
SLU7 SLU7 O95391 Pre-mRNA-splicing factor SLU7 chr5 Not Cancer Driver No 1 hippie 75 436 63 63 0
SMAD9 SMAD9 O15198 Mothers against decapentaplegic homolog 9 chr13 Not Cancer Driver No 1 hippie 79 132 14 14 1
SMARCD1 SMARCD1 Q96GM5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 chr12 Census, Compendium Yes 1 hippie 48 216 18 18 2
SMG7_ENST00000347615 SMG7 Q92540 Nonsense-mediated mRNA decay factor SMG7 chr1 Not Cancer Driver No 2 hippie, biogrid 134 664 82 82 0
SNF8 SNF8 Q96H20 Vacuolar-sorting protein SNF8 chr17 Not Cancer Driver No 1 hippie 30 10 2 2 0
SOST SOST Q9BQB4 Sclerostin chr17 Not Cancer Driver No 2 hippie, biogrid 30 90 12 12 3
SPATA22_ENST00000397168 SPATA22 Q8NHS9 Spermatogenesis-associated protein 22 chr17 Not Cancer Driver No 1 hippie 71 220 40 40 0
SPIN1 SPIN1 Q9Y657 Spindlin-1 chr9 Not Cancer Driver No 1 hippie 31 132 18 18 0
SPIN4 SPIN4 Q56A73 Spindlin-4 chrX Not Cancer Driver No 1 hippie, biogrid 35 63 9 9 0
SPSB1_ENST00000377399 SPSB1 Q96BD6 SPRY domain-containing SOCS box protein 1 chr1 Not Cancer Driver No 1 hippie 35 26 3 3 0
SRGAP3 SRGAP3 O43295 SLIT-ROBO Rho GTPase-activating protein 3 chr3 Census, Compendium Yes 1 hippie 195 549 97 97 0
SSX2IP SSX2IP Q9Y2D8 Afadin- and alpha-actinin-binding protein chr1 Not Cancer Driver No 1 hippie 82 265 31 31 0
STARD10_ENST00000543304 STARD10 Q9Y365 START domain-containing protein 10 chr11 Not Cancer Driver No 1 hippie 39 75 6 6 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX Not Cancer Driver No 1 hippie 59 15 1 1 0
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 Census, Compendium Yes 2 hippie, biogrid 122 516 93 93 0
TDO2 TDO2 P48775 Tryptophan 2,3-dioxygenase chr4 Not Cancer Driver No 1 hippie 64 31 9 9 1
TEX35 TEX35 Q5T0J7 Testis-expressed protein 35 chr1 Not Cancer Driver No 1 hippie 60 182 39 39 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 3 hippie, biogrid 68 169 23 23 0
THEMIS_ENST00000368250 THEMIS Q8N1K5 Protein THEMIS chr6 Not Cancer Driver No 1 hippie 208 111 34 34 0
TMED5 TMED5 Q9Y3A6 Transmembrane emp24 domain-containing protein 5 chr1 Not Cancer Driver No 1 hippie 23 1 0 0 0
TP73 TP73 O15350 Tumor protein p73 chr1 Not Cancer Driver No 2 hippie, biogrid 82 443 55 55 0
TRIB2 TRIB2 Q92519 Tribbles homolog 2 chr2 Not Cancer Driver No 1 hippie 64 43 5 5 0
TSC1 TSC1 Q92574 Hamartin chr9 Census, Compendium Yes 1 hippie 135 732 78 78 11
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 hippie, biogrid 59 52 11 11 8
TUBB8 TUBB8 Q3ZCM7 Tubulin beta-8 chain chr10 Not Cancer Driver No 1 hippie, biogrid 103 53 18 18 13
UBP1 UBP1 Q9NZI7 Upstream-binding protein 1 chr3 Not Cancer Driver No 3 hippie, biogrid 58 233 29 29 0
UBR4 UBR4 Q5T4S7 E3 ubiquitin-protein ligase UBR4 chr1 Not Cancer Driver No 1 hippie, biogrid 565 1066 119 119 0
UBR7 UBR7 Q8N806 Putative E3 ubiquitin-protein ligase UBR7 chr14 Not Cancer Driver No 1 hippie 41 103 13 13 0
UBXN10 UBXN10 Q96LJ8 UBX domain-containing protein 10 chr1 Not Cancer Driver No 1 hippie 51 254 48 48 0
WDFY3 WDFY3 Q8IZQ1 WD repeat and FYVE domain-containing protein 3 chr4 Not Cancer Driver No 1 hippie 455 605 73 73 1
ZFC3H1 ZFC3H1 O60293 Zinc finger C3H1 domain-containing protein chr12 Not Cancer Driver No 2 hippie, biogrid 210 1025 115 115 0
ZNF436_ENST00000374608 ZNF436 Q9C0F3 Zinc finger protein 436 chr1 Not Cancer Driver No 1 hippie 62 195 28 28 0
ZNF557_ENST00000414706 ZNF557 Q8N988 Zinc finger protein 557 chr19 Not Cancer Driver No 1 hippie 81 115 25 25 0
ZNF57 ZNF57 Q68EA5 Zinc finger protein 57 chr19 Not Cancer Driver No 1 hippie 79 112 16 16 0
ZSCAN9_ENST00000531979 ZSCAN9 O15535 Zinc finger and SCAN domain-containing protein 9 chr6 Not Cancer Driver No 1 hippie 40 149 10 10 0