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PRKCG ,PRKCG ,P05129
  • Uniprot Accession= P05129
  • Ensembl Transcript= ENST00000263431.3
  • Uniprot Name= PRKCG
  • Name= Protein kinase C gamma type
  • Chromosome= chr19
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 25
  • Number of Interaction partner in biogrid: 4
  • Number of Interaction partner in hippie: 105
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AFAP1_ENST00000358461 AFAP1 Q8N556 Actin filament-associated protein 1 chr4 Not Cancer Driver No 1 hippie 104 487 60 60 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 intact, hippie 88 166 22 22 11
ANXA7 ANXA7 P20073 Annexin A7 chr10 Not Cancer Driver No 1 hippie 68 215 37 37 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARHGEF25_ENST00000286494 ARHGEF25 Q86VW2 Rho guanine nucleotide exchange factor 25 chr12 Not Cancer Driver No 1 hippie 80 241 35 35 0
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 Not Cancer Driver No 1 hippie 106 301 39 39 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 intact, hippie 17 112 9 9 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 Not Cancer Driver No 1 hippie 304 189 60 60 108
CCHCR1_ENST00000376266 CCHCR1 Q8TD31 Coiled-coil alpha-helical rod protein 1 chr6 Not Cancer Driver No 1 hippie 116 565 88 88 0
CD5 CD5 P06127 T-cell surface glycoprotein CD5 chr11 Not Cancer Driver No 1 hippie 67 146 19 19 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 intact, hippie 52 214 31 31 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CHAT CHAT P28329 Choline O-acetyltransferase chr10 Not Cancer Driver No 1 hippie 155 193 24 24 10
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CYTH2_ENST00000641098 CYTH2 Q99418 Cytohesin-2 chr19 Not Cancer Driver No 1 hippie 55 93 12 12 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 Not Cancer Driver No 1 hippie 144 680 125 125 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie, biogrid 44 37 2 2 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 intact, hippie 37 153 16 16 0
DNAJC10 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 110 36 3 3 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 1 hippie 23 46 6 6 1
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 Not Cancer Driver No 1 hippie 96 514 64 64 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 Not Cancer Driver No 1 hippie 26 54 6 6 0
EPHB1 EPHB1 P54762 Ephrin type-B receptor 1 chr3 Not Cancer Driver No 1 hippie 316 67 17 17 0
EXOC5 EXOC5 O00471 Exocyst complex component 5 chr14 Not Cancer Driver No 1 hippie 59 57 4 4 0
FAM167A FAM167A Q96KS9 Protein FAM167A chr8 Not Cancer Driver No 1 intact, hippie 33 116 17 17 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie 75 243 38 38 1
G6PD_ENST00000621232 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX Not Cancer Driver No 1 intact, hippie 86 28 3 3 58
GABRA1_ENST00000638112 GABRA1 P14867 Gamma-aminobutyric acid receptor subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 175 58 31 31 6
GABRA4 GABRA4 P48169 Gamma-aminobutyric acid receptor subunit alpha-4 chr4 Not Cancer Driver No 1 hippie 191 179 82 82 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 1 hippie 65 288 42 42 62
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie 86 110 26 26 50
GJA3 GJA3 Q9Y6H8 Gap junction alpha-3 protein chr13 Not Cancer Driver No 1 hippie 37 211 13 13 20
GRIA4_ENST00000530497 GRIA4 P48058 Glutamate receptor 4 chr11 Not Cancer Driver No 1 hippie 227 63 25 25 4
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 Not Cancer Driver No 1 hippie 88 190 15 15 13
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 Not Cancer Driver No 1 hippie 413 426 147 147 11
GRIN2D GRIN2D O15399 Glutamate receptor ionotropic, NMDA 2D chr19 Not Cancer Driver No 1 hippie 125 467 15 15 1
GRK2 GRK2 P25098 Beta-adrenergic receptor kinase 1 chr11 Not Cancer Driver No 1 hippie 77 87 8 8 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 Not Cancer Driver No 1 hippie 312 323 51 51 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 Not Cancer Driver No 1 hippie 55 180 8 8 0
HABP4 HABP4 Q5JVS0 Intracellular hyaluronan-binding protein 4 chr9 Not Cancer Driver No 1 hippie 32 413 32 32 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 2 intact, hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 2 intact, hippie 100 254 43 43 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 24 200 13 13 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie 80 351 24 24 0
HSPA6 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 Not Cancer Driver No 1 intact, hippie 112 235 27 27 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 149 251 52 52 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 intact, hippie 10 118 8 8 20
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 61 82 6 6 2
IBTK IBTK Q9P2D0 Inhibitor of Bruton tyrosine kinase chr6 Not Cancer Driver No 1 hippie 146 364 39 39 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 Not Cancer Driver No 1 hippie 161 1072 133 133 2
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 Not Cancer Driver No 1 hippie 147 59 9 9 15
IVNS1ABP IVNS1ABP Q9Y6Y0 Influenza virus NS1A-binding protein chr1 Not Cancer Driver No 1 hippie 85 90 12 12 0
KRT19 KRT19 P08727 Keratin, type I cytoskeletal 19 chr17 Not Cancer Driver No 1 hippie 57 165 19 19 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 Not Cancer Driver No 1 hippie 99 175 15 15 10
LTBP1 LTBP1 Q14766 Latent-transforming growth factor beta-binding protein 1 chr2 Not Cancer Driver No 1 intact, hippie 300 518 78 78 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MARK4 MARK4 Q96L34 MAP/microtubule affinity-regulating kinase 4 chr19 Not Cancer Driver No 1 hippie 94 403 46 46 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 Census, Compendium Yes 1 hippie 228 402 62 62 4
NOXA1 NOXA1 Q86UR1 NADPH oxidase activator 1 chr9 Not Cancer Driver No 1 hippie 27 215 14 14 0
NRGN NRGN Q92686 Neurogranin chr11 Not Cancer Driver No 1 hippie 5 76 5 5 0
NUMB_ENST00000355058 NUMB P49757 Protein numb homolog chr14 Not Cancer Driver No 1 hippie 70 490 58 58 0
OCLN OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 hippie 54 244 21 21 1
PA2G4 PA2G4 Q9UQ80 Proliferation-associated protein 2G4 chr12 Not Cancer Driver No 1 hippie 45 128 18 18 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie 200 1144 170 170 2
PARD6A PARD6A Q9NPB6 Partitioning defective 6 homolog alpha chr16 Not Cancer Driver No 1 hippie 25 177 13 13 0
PARD6B PARD6B Q9BYG5 Partitioning defective 6 homolog beta chr20 Not Cancer Driver No 1 hippie 50 166 23 23 0
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 Not Cancer Driver No 1 intact, hippie 91 139 13 13 0
PDLIM5_ENST00000317968 PDLIM5 Q96HC4 PDZ and LIM domain protein 5 chr4 Not Cancer Driver No 1 hippie 89 372 57 57 0
PEBP1 PEBP1 P30086 Phosphatidylethanolamine-binding protein 1 chr12 Not Cancer Driver No 1 hippie 23 76 13 13 0
PIAS1_ENST00000249636 PIAS1 O75925 E3 SUMO-protein ligase PIAS1 chr15 Not Cancer Driver No 1 hippie 80 241 43 43 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 Not Cancer Driver No 1 intact, hippie 50 49 3 3 0
PNMA1 PNMA1 Q8ND90 Paraneoplastic antigen Ma1 chr14 Not Cancer Driver No 1 hippie 48 56 9 9 0
PPP1R14A PPP1R14A Q96A00 Protein phosphatase 1 regulatory subunit 14A chr19 Not Cancer Driver No 1 hippie 14 113 10 10 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 4 intact, hippie, biogrid 94 154 22 22 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 Census, Compendium Yes 1 hippie, biogrid 205 148 40 40 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 Not Cancer Driver No 1 hippie 172 151 43 43 5
PRPS1 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX Not Cancer Driver No 1 hippie 50 0 0 0 14
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX Not Cancer Driver No 1 hippie 56 4 1 1 0
PRPSAP1 PRPSAP1 Q14558-2 Isoform 2 of Phosphoribosyl pyrophosphate synthase-associated protein 1 chr17 Not Cancer Driver No 1 hippie 52 50 5 5 0
PRPSAP2 PRPSAP2 O60256 Phosphoribosyl pyrophosphate synthase-associated protein 2 chr17 Not Cancer Driver No 1 hippie 54 19 3 3 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 intact, hippie 49 140 25 25 0
RANBP10 RANBP10 Q6VN20 Ran-binding protein 10 chr16 Not Cancer Driver No 1 hippie 91 297 50 50 0
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 Not Cancer Driver No 1 hippie 73 413 30 30 0
RCN2_ENST00000394885 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 intact, hippie 35 125 11 11 0
RGS2 RGS2 P41220 Regulator of G-protein signaling 2 chr1 Not Cancer Driver No 1 hippie 30 50 4 4 0
SAMD3_ENST00000368134 SAMD3 Q8N6K7 Sterile alpha motif domain-containing protein 3 chr6 Not Cancer Driver No 1 intact, hippie 134 51 11 11 0
SCN3A_ENST00000360093 SCN3A Q9NY46 Sodium channel protein type 3 subunit alpha chr2 Not Cancer Driver No 1 hippie 415 432 83 83 6
SDC2 SDC2 P34741 Syndecan-2 chr8 Not Cancer Driver No 1 hippie 41 127 24 24 0
SLC25A3 SLC25A3 Q00325 Phosphate carrier protein, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie 49 32 4 4 1
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 Not Cancer Driver No 1 hippie 89 256 31 31 0
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie 74 270 39 39 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 Not Cancer Driver No 1 hippie 97 111 23 23 18
TCF25 TCF25 Q9BQ70 Transcription factor 25 chr16 Not Cancer Driver No 1 hippie 82 280 35 35 0
TCP10L TCP10L Q8TDR4 T-complex protein 10A homolog 1 chr21 Not Cancer Driver No 1 intact, hippie 32 213 32 32 0
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 Not Cancer Driver No 1 hippie 370 810 194 194 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 Compendium Yes 1 hippie 150 508 59 59 0
TRIM5 TRIM5 Q9C035 Tripartite motif-containing protein 5 chr11 Not Cancer Driver No 1 hippie 71 77 11 11 0
TUBB4B TUBB4B P68371 Tubulin beta-4B chain chr9 Not Cancer Driver No 1 intact, hippie 52 65 11 11 2
UBE2T UBE2T Q9NPD8 Ubiquitin-conjugating enzyme E2 T chr1 Not Cancer Driver No 1 hippie 12 97 9 9 1
VTN VTN P04004 Vitronectin chr17 Not Cancer Driver No 1 hippie 76 168 29 29 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 hippie 22 109 4 4 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 intact, hippie 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 hippie 26 77 9 9 2