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PRKAA2 ,PRKAA2 ,P54646
  • Uniprot Accession= P54646
  • Ensembl Transcript= ENST00000371244.8
  • Uniprot Name= PRKAA2
  • Name= 5'-AMP-activated protein kinase catalytic subunit alpha-2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 114
  • Number of Interaction partner in biogrid: 42
  • Number of Interaction partner in hippie: 213
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 Census, Compendium Yes 1 intact, hippie 55 360 39 39 0
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 2 intact, hippie 56 361 38 38 0
ACACB_ENST00000377848 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 Not Cancer Driver No 1 hippie 388 342 62 62 0
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 Census, Compendium Yes 1 intact, hippie, biogrid 98 56 6 6 0
AES_ENST00000327141 TLE5 Q08117 TLE family member 5 chr19 Not Cancer Driver No 2 intact 16 77 7 7 0
AGL_ENST00000361915 AGL P35573 Glycogen debranching enzyme chr1 Not Cancer Driver No 1 intact, hippie 182 143 23 23 1
AIMP2 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 Not Cancer Driver No 1 hippie 46 61 8 8 0
AKAP8L AKAP8L Q9ULX6 A-kinase anchor protein 8-like chr19 Not Cancer Driver No 1 intact, hippie 76 510 61 61 0
AMOT AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 2 intact, hippie 161 909 128 128 0
AMOTL2_ENST00000422605 AMOTL2 Q9Y2J4 Angiomotin-like protein 2 chr3 Not Cancer Driver No 1 hippie 94 741 93 93 0
ANAPC11_ENST00000579978 ANAPC11 Q9NYG5 Anaphase-promoting complex subunit 11 chr17 Not Cancer Driver No 1 intact, hippie 7 0 0 0 0
APOD APOD P05090 Apolipoprotein D chr3 Not Cancer Driver No 1 intact, hippie, biogrid 34 13 2 2 0
APPBP2 APPBP2 Q92624 Amyloid protein-binding protein 2 chr17 Not Cancer Driver No 1 hippie 61 10 0 0 0
ARRDC3 ARRDC3 Q96B67 Arrestin domain-containing protein 3 chr5 Not Cancer Driver No 1 hippie 52 95 12 12 0
AVPI1 AVPI1 Q5T686 Arginine vasopressin-induced protein 1 chr10 Not Cancer Driver No 1 intact, hippie 21 115 14 14 0
BAIAP2L1 BAIAP2L1 Q9UHR4 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 chr7 Not Cancer Driver No 1 intact, hippie 76 293 42 42 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie, biogrid 27 192 24 24 0
C19orf47 C19orf47 Q8N9M1 Uncharacterized protein C19orf47 chr19 Not Cancer Driver No 1 hippie 41 301 30 30 0
CALCOCO1 CALCOCO1 Q9P1Z2 Calcium-binding and coiled-coil domain-containing protein 1 chr12 Not Cancer Driver No 1 intact, hippie 88 486 59 59 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 intact, hippie 42 212 19 19 0
CAMKK2 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 65 281 35 35 0
CBWD2 CBWD2 Q8IUF1 COBW domain-containing protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 20 54 6 6 0
CCDC172 CCDC172 P0C7W6 Coiled-coil domain-containing protein 172 chr10 Not Cancer Driver No 1 intact, hippie 64 72 14 14 0
CCDC33_ENST00000558821 CCDC33 Q8N5R6-4 Isoform 4 of Coiled-coil domain-containing protein 33 chr15 Not Cancer Driver No 1 hippie 60 288 51 51 0
CCNB1IP1 CCNB1IP1 Q9NPC3 E3 ubiquitin-protein ligase CCNB1IP1 chr14 Census Yes 1 hippie 43 68 13 13 0
CDC42EP1 CDC42EP1 Q00587 Cdc42 effector protein 1 chr22 Not Cancer Driver No 1 intact, hippie 52 371 47 47 0
CDR2 CDR2 Q01850 Cerebellar degeneration-related protein 2 chr16 Not Cancer Driver No 1 hippie 50 287 26 26 0
CDX4 CDX4 O14627 Homeobox protein CDX-4 chrX Not Cancer Driver No 1 intact, hippie 86 188 54 54 0
CEP170B_ENST00000556508 CEP170B Q9Y4F5 Centrosomal protein of 170 kDa protein B chr14 Not Cancer Driver No 1 intact, hippie 126 1438 117 117 0
CERS2_ENST00000368954 CERS2 Q96G23 Ceramide synthase 2 chr1 Not Cancer Driver No 1 hippie, biogrid 38 36 4 4 0
CLPB CLPB Q9H078 Caseinolytic peptidase B protein homolog chr11 Not Cancer Driver No 1 intact, hippie, biogrid 69 224 25 25 11
CPSF7_ENST00000394888 CPSF7 Q8N684 Cleavage and polyadenylation specificity factor subunit 7 chr11 Not Cancer Driver No 1 hippie 55 398 52 52 0
CTAG2 CTAG2 O75638 Cancer/testis antigen 2 chrX Not Cancer Driver No 1 intact, hippie 54 198 52 52 0
CTNNA3 CTNNA3 Q9UI47 Catenin alpha-3 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 269 186 50 50 1
CYSRT1 CYSRT1 B8A4K4 Cysteine-rich tail protein 1 chr9 Not Cancer Driver No 1 intact, hippie 9 142 5 5 0
DCAF7 DCAF7 P61962 DDB1- and CUL4-associated factor 7 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 48 0 0 0 0
DCLRE1C DCLRE1C Q96SD1 Protein artemis chr10 Not Cancer Driver No 3 intact, hippie, biogrid 76 277 26 26 3
DCT_ENST00000377028 DCT P40126 L-dopachrome tautomerase chr13 Not Cancer Driver No 1 hippie 113 19 4 4 2
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 Not Cancer Driver No 1 hippie 47 113 18 18 0
DNAJA4_ENST00000394852 DNAJA4 Q8WW22 DnaJ homolog subfamily A member 4 chr15 Not Cancer Driver No 1 hippie 43 110 6 6 0
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 1 hippie 35 196 26 26 0
DNAJC21_ENST00000342382 DNAJC21 Q5F1R6 DnaJ homolog subfamily C member 21 chr5 Not Cancer Driver No 1 hippie, biogrid 82 342 51 51 1
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 intact, hippie 138 270 43 43 22
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie 203 702 78 78 4
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 Not Cancer Driver No 1 intact, hippie 97 437 58 58 0
E2F6 E2F6 O75461 Transcription factor E2F6 chr2 Not Cancer Driver No 1 hippie 20 105 10 10 0
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 Not Cancer Driver No 1 hippie 104 311 39 39 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 Not Cancer Driver No 1 intact, hippie 125 669 69 69 0
ENTR1 ENTR1 Q96C92 Endosome-associated-trafficking regulator 1 chr9 Not Cancer Driver No 1 hippie 64 267 38 38 0
EPM2A EPM2A O95278 Laforin chr6 Not Cancer Driver No 1 hippie 29 46 1 1 19
EPN2 EPN2 O95208 Epsin-2 chr17 Not Cancer Driver No 1 intact, hippie 73 543 61 61 0
ESYT1_ENST00000394048 ESYT1 Q9BSJ8 Extended synaptotagmin-1 chr12 Not Cancer Driver No 1 hippie, biogrid 126 278 32 32 0
FLCN FLCN Q8NFG4 Folliculin chr17 Census, Compendium Yes 1 intact, hippie 59 157 19 19 5
FNDC3B_ENST00000416957 FNDC3B Q53EP0 Fibronectin type III domain-containing protein 3B chr3 Not Cancer Driver No 1 intact, hippie 164 433 53 53 0
FNIP1 FNIP1 Q8TF40 Folliculin-interacting protein 1 chr5 Not Cancer Driver No 1 intact, hippie 143 384 44 44 0
FOS FOS P01100 Protein c-Fos chr14 Not Cancer Driver No 1 intact, hippie 45 245 33 33 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GFPT1 GFPT1 Q06210 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 chr2 Not Cancer Driver No 1 hippie 81 75 8 8 13
GIGYF1_ENST00000646601 GIGYF1 O75420 GRB10-interacting GYF protein 1 chr7 Not Cancer Driver No 1 hippie 138 857 115 115 0
GLG1_ENST00000422840 GLG1 Q92896 Golgi apparatus protein 1 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 134 103 7 7 0
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 Census, Compendium Yes 1 intact, hippie 206 1015 184 184 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 2 intact, hippie 115 854 96 96 0
GOLGA6A GOLGA6A Q9NYA3 Golgin subfamily A member 6A chr15 Not Cancer Driver No 1 intact, hippie 51 633 44 44 0
GPT_ENST00000528431 GPT P24298 Alanine aminotransferase 1 chr8 Not Cancer Driver No 1 hippie 52 51 9 9 0
GRAP2_ENST00000407075 GRAP2 O75791 GRB2-related adapter protein 2 chr22 Not Cancer Driver No 1 hippie 59 151 20 20 0
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 76 29 6 6 1
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 intact, hippie, biogrid 56 146 13 13 0
GYG1 GYG1 P46976 Glycogenin-1 chr3 Not Cancer Driver No 1 intact, hippie 38 21 3 3 3
GYS1 GYS1 P13807 Glycogen [starch] synthase, muscle chr19 Not Cancer Driver No 1 intact, hippie 98 127 18 18 0
HAT1 HAT1 O14929 Histone acetyltransferase type B catalytic subunit chr2 Not Cancer Driver No 1 hippie 51 14 2 2 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 55 319 41 41 0
HNF4A HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 Not Cancer Driver No 1 hippie 135 127 48 48 5
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HOMEZ HOMEZ Q8IX15 Homeobox and leucine zipper protein Homez chr14 Not Cancer Driver No 1 intact, hippie 83 401 70 70 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 intact, hippie 36 25 6 6 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 intact, hippie 100 254 43 43 0
IKZF1 IKZF1 Q13422 DNA-binding protein Ikaros chr7 Census, Compendium Yes 1 intact, hippie 143 326 92 92 5
IKZF3 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 Census, Compendium Yes 1 hippie 106 284 60 60 1
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 intact, hippie 190 280 57 57 64
IPO7 IPO7 O95373 Importin-7 chr11 Not Cancer Driver No 1 hippie, biogrid 138 202 30 30 0
KCTD1 KCTD1 Q719H9 BTB/POZ domain-containing protein KCTD1 chr18 Not Cancer Driver No 1 intact, hippie 45 36 5 5 8
KCTD9 KCTD9 Q7L273 BTB/POZ domain-containing protein KCTD9 chr8 Not Cancer Driver No 1 intact, hippie 48 27 3 3 0
KIAA1328 KIAA1328 Q86T90 Protein hinderin chr18 Not Cancer Driver No 1 intact, hippie 77 442 66 66 0
KIF16B_ENST00000354981 KIF16B Q96L93 Kinesin-like protein KIF16B chr20 Not Cancer Driver No 1 hippie 248 436 74 74 0
KIF24 KIF24 Q5T7B8 Kinesin-like protein KIF24 chr9 Not Cancer Driver No 1 intact, hippie 126 898 90 90 0
KIFC3_ENST00000379655 KIFC3 Q9BVG8 Kinesin-like protein KIFC3 chr16 Not Cancer Driver No 2 intact, hippie 84 487 42 42 0
KRT16 KRT16 P08779 Keratin, type I cytoskeletal 16 chr17 Not Cancer Driver No 1 intact, hippie 83 152 28 28 16
KRT31 KRT31 Q15323 Keratin, type I cuticular Ha1 chr17 Not Cancer Driver No 1 hippie 116 64 16 16 0
KRTAP1-3 KRTAP1-3 Q8IUG1 Keratin-associated protein 1-3 chr17 Not Cancer Driver No 1 intact, hippie 31 0 0 0 0
KRTAP10-3 KRTAP10-3 P60369 Keratin-associated protein 10-3 chr21 Not Cancer Driver No 1 hippie 30 0 0 0 0
KRTAP10-9 KRTAP10-9 P60411 Keratin-associated protein 10-9 chr21 Not Cancer Driver No 1 intact, hippie 49 1 0 0 0
L3MBTL3_ENST00000368136 L3MBTL3 Q96JM7 Lethal(3)malignant brain tumor-like protein 3 chr6 Not Cancer Driver No 2 intact, hippie 117 351 59 59 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 2 hippie, biogrid 13 96 7 7 0
LCN2_ENST00000277480 LCN2 P80188 Neutrophil gelatinase-associated lipocalin chr9 Not Cancer Driver No 1 hippie 29 4 3 3 0
LEP LEP P41159 Leptin chr7 Not Cancer Driver No 1 hippie 29 0 0 0 2
LRRTM3 LRRTM3 Q86VH5 Leucine-rich repeat transmembrane neuronal protein 3 chr10 Not Cancer Driver No 1 hippie 142 136 31 31 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie 78 508 66 66 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 Not Cancer Driver No 1 hippie, biogrid 26 12 1 1 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 Not Cancer Driver No 1 hippie 197 242 29 29 0
MAP3K6 MAP3K6 O95382 Mitogen-activated protein kinase kinase kinase 6 chr1 Not Cancer Driver No 1 intact, hippie 108 390 31 31 0
MAST3 MAST3 O60307 Microtubule-associated serine/threonine-protein kinase 3 chr19 Not Cancer Driver No 1 intact, hippie 169 783 100 100 0
MDP1 MDP1 Q86V88 Magnesium-dependent phosphatase 1 chr14 Not Cancer Driver No 1 hippie 25 35 8 8 0
MGA MGA Q8IWI9 MAX gene-associated protein chr15 Compendium Yes 1 intact, hippie, biogrid 341 2317 259 259 0
MID1IP1_ENST00000336949 MID1IP1 Q9NPA3 Mid1-interacting protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 23 83 6 6 0
MKRN3 MKRN3 Q13064 Probable E3 ubiquitin-protein ligase makorin-3 chr15 Not Cancer Driver No 1 intact, hippie 197 201 99 99 4
MLF2_ENST00000542154 MLF2 Q15773 Myeloid leukemia factor 2 chr12 Not Cancer Driver No 1 hippie 37 187 32 32 0
MORC4 MORC4 Q8TE76 MORC family CW-type zinc finger protein 4 chrX Not Cancer Driver No 1 hippie, biogrid 139 377 48 48 0
MORN3 MORN3 Q6PF18 MORN repeat-containing protein 3 chr12 Not Cancer Driver No 1 intact, hippie 42 63 9 9 0
MRFAP1 MRFAP1 Q9Y605 MORF4 family-associated protein 1 chr4 Not Cancer Driver No 1 hippie 17 71 10 10 0
MTUS2 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 2 intact, hippie 370 1208 329 329 0
MXRA5 MXRA5 Q9NR99 Matrix-remodeling-associated protein 5 chrX Not Cancer Driver No 1 hippie 753 1392 397 397 1
MYCL_ENST00000372816 MYCL P12524 Protein L-Myc chr1 Census Yes 1 intact, hippie 47 275 43 43 0
MYOZ1 MYOZ1 Q9NP98 Myozenin-1 chr10 Not Cancer Driver No 1 hippie 49 223 39 39 0
NAB2 NAB2 Q15742 NGFI-A-binding protein 2 chr12 Census Yes 1 intact, hippie 67 395 51 51 0
NACA_ENST00000356769 NACA Q13765 Nascent polypeptide-associated complex subunit alpha chr12 Census Yes 1 hippie, biogrid 37 143 26 26 0
NECAB2 NECAB2 Q7Z6G3 N-terminal EF-hand calcium-binding protein 2 chr16 Not Cancer Driver No 1 hippie 46 122 9 9 0
NIPSNAP1 NIPSNAP1 Q9BPW8 Protein NipSnap homolog 1 chr22 Not Cancer Driver No 1 intact, hippie 31 9 0 0 0
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX Census, Compendium Yes 1 hippie 101 349 64 64 0
NOTCH2NLA NOTCH2NLA Q7Z3S9 Notch homolog 2 N-terminal-like protein A chr1 Not Cancer Driver No 1 intact, hippie 68 17 2 2 0
NRAP_ENST00000359988 NRAP Q86VF7 Nebulin-related-anchoring protein chr10 Not Cancer Driver No 1 hippie 302 706 139 139 0
NRBF2 NRBF2 Q96F24 Nuclear receptor-binding factor 2 chr10 Not Cancer Driver No 1 intact, hippie 34 224 25 25 0
NUBP2 NUBP2 Q9Y5Y2 Cytosolic Fe-S cluster assembly factor NUBP2 chr16 Not Cancer Driver No 1 hippie, biogrid 38 14 0 0 0
NUTM1_ENST00000614490 NUTM1 Q86Y26 NUT family member 1 chr15 Census Yes 1 intact, hippie 202 967 175 175 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 intact, hippie, biogrid 200 1144 170 170 2
PARS2 PARS2 Q7L3T8 Probable proline--tRNA ligase, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 50 8 2 2 0
PBXIP1 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 100 605 86 86 0
PEX14 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 Not Cancer Driver No 1 hippie, biogrid 38 266 28 28 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 Not Cancer Driver No 1 hippie 68 97 18 18 0
PIGR PIGR P01833 Polymeric immunoglobulin receptor chr1 Not Cancer Driver No 1 hippie 126 177 37 37 0
PIH1D3_ENST00000372453 DNAAF6 Q9NQM4 Dynein axonemal assembly factor 6 chrX Not Cancer Driver No 1 intact 23 114 12 12 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 Not Cancer Driver No 1 intact, hippie 318 121 39 39 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLEKHN1 PLEKHN1 Q494U1 Pleckstrin homology domain-containing family N member 1 chr1 Not Cancer Driver No 1 intact, hippie 59 369 37 37 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 72 44 4 4 3
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 Not Cancer Driver No 1 hippie 181 609 148 148 0
PPM1E PPM1E Q8WY54 Protein phosphatase 1E chr17 Not Cancer Driver No 1 hippie 114 384 53 53 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 Not Cancer Driver No 1 hippie 53 242 24 24 0
PPP1R32 PPP1R32 Q7Z5V6 Protein phosphatase 1 regulatory subunit 32 chr11 Not Cancer Driver No 1 intact, hippie 70 379 55 55 0
PPP1R3C PPP1R3C Q9UQK1 Protein phosphatase 1 regulatory subunit 3C chr10 Not Cancer Driver No 1 hippie 37 16 0 0 0
PPP6C_ENST00000373547 PPP6C O00743 Serine/threonine-protein phosphatase 6 catalytic subunit chr9 Census, Compendium Yes 1 intact, hippie, biogrid 63 0 0 0 0
PPP6R3_ENST00000393800 PPP6R3 Q5H9R7 Serine/threonine-protein phosphatase 6 regulatory subunit 3 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 108 389 52 52 0
PRDM6 PRDM6 Q9NQX0 Putative histone-lysine N-methyltransferase PRDM6 chr5 Not Cancer Driver No 1 intact, hippie 29 241 7 7 2
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 2 intact, hippie 72 124 17 17 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 Not Cancer Driver No 1 intact, hippie 128 98 26 26 0
PRKAB1 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 Not Cancer Driver No 7 intact, hippie, biogrid 39 124 13 13 0
PRKAB2 PRKAB2 O43741 5'-AMP-activated protein kinase subunit beta-2 chr1 Not Cancer Driver No 7 intact, hippie, biogrid 31 110 12 12 0
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 Not Cancer Driver No 10 intact, hippie, biogrid 35 25 2 2 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 Not Cancer Driver No 5 intact, hippie, biogrid 76 240 45 45 7
PRKAG3_ENST00000529249 PRKAG3 Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 74 144 25 25 0
PRKAR1B_ENST00000403562 PRKAR1B P31321 cAMP-dependent protein kinase type I-beta regulatory subunit chr7 Not Cancer Driver No 1 intact, hippie 53 71 13 13 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 intact, hippie, biogrid 538 421 61 61 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRPH PRPH P41219 Peripherin chr12 Not Cancer Driver No 1 intact, hippie 37 239 20 20 0
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX Not Cancer Driver No 1 hippie, biogrid 56 4 1 1 0
PSMD11_ENST00000457654 PSMD11 O00231 26S proteasome non-ATPase regulatory subunit 11 chr17 Not Cancer Driver No 1 hippie 51 0 0 0 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 11 52 3 3 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 27 11 0 0 4
RASAL3 RASAL3 Q86YV0 RAS protein activator like-3 chr19 Not Cancer Driver No 1 intact, hippie 114 536 68 68 0
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 intact, hippie 202 578 75 75 0
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX Not Cancer Driver No 1 hippie 67 138 19 19 0
RBPMS_ENST00000320203 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 Not Cancer Driver No 1 intact, hippie 23 87 11 11 0
REL REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 2 intact, hippie 68 363 43 43 0
RFX6 RFX6 Q8HWS3 DNA-binding protein RFX6 chr6 Not Cancer Driver No 1 intact, hippie 239 422 94 94 3
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 Not Cancer Driver No 1 hippie 131 421 76 76 0
RNF11 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie 17 76 7 7 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 176 241 21 21 0
SERTAD3_ENST00000392028 SERTAD3 Q9UJW9 SERTA domain-containing protein 3 chr19 Not Cancer Driver No 1 hippie 28 124 17 17 0
SH3PXD2A_ENST00000369774 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 Not Cancer Driver No 1 hippie 141 797 101 101 0
SKIV2L SKIV2L Q15477 Helicase SKI2W chr6 Not Cancer Driver No 1 intact, hippie 140 390 54 54 1
SLA2 SLA2 Q9H6Q3 Src-like-adapter 2 chr20 Not Cancer Driver No 1 intact, hippie 32 43 9 9 0
SMC1A SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX Census, Compendium Yes 1 intact, hippie 200 717 114 114 21
SMN1_ENST00000503079 SMN1 Q16637-2 Isoform SMN-delta5 of Survival motor neuron protein chr5 Not Cancer Driver No 1 hippie 2 181 2 2 0
SMYD2 SMYD2 Q9NRG4 N-lysine methyltransferase SMYD2 chr1 Not Cancer Driver No 1 hippie, biogrid 42 12 0 0 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 62 488 56 56 0
SOHLH1_ENST00000298466 SOHLH1 Q5JUK2 Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 chr9 Not Cancer Driver No 1 intact, hippie 48 252 39 39 0
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 Not Cancer Driver No 1 intact, hippie 46 168 26 26 0
SRSF2 SRSF2 Q01130 Serine/arginine-rich splicing factor 2 chr17 Census, Compendium Yes 1 hippie, biogrid 38 219 38 38 0
STAC2 STAC2 Q6ZMT1 SH3 and cysteine-rich domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie 56 228 36 36 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 intact, hippie 70 387 45 45 13
STIM2_ENST00000467087 STIM2 Q9P246 Stromal interaction molecule 2 chr4 Not Cancer Driver No 3 intact, hippie, biogrid 82 387 45 45 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 Census, Compendium Yes 3 intact, hippie 75 135 14 14 9
SUCLG1 SUCLG1 P53597 Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 48 57 8 8 3
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 141 662 136 136 13
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 Not Cancer Driver No 1 hippie 77 275 44 44 4
TIFA_ENST00000500655 TIFA Q96CG3 TRAF-interacting protein with FHA domain-containing protein A chr4 Not Cancer Driver No 1 hippie 17 32 5 5 0
TMOD1_ENST00000395211 TMOD1 P28289 Tropomodulin-1 chr9 Not Cancer Driver No 1 hippie 41 195 29 29 0
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRIP13 TRIP13 Q15645 Pachytene checkpoint protein 2 homolog chr5 Not Cancer Driver No 1 intact, hippie 62 30 6 6 1
TRIP6 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 Not Cancer Driver No 2 intact, hippie 62 268 19 19 0
TSC22D4 TSC22D4 Q9Y3Q8 TSC22 domain family protein 4 chr7 Not Cancer Driver No 1 intact, hippie 33 363 29 29 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
UBE2O UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 Not Cancer Driver No 1 intact, hippie, biogrid 129 716 68 68 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 109 141 24 24 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 Not Cancer Driver No 2 intact, hippie 142 588 77 77 0
ULK2_ENST00000361658 ULK2 Q8IYT8 Serine/threonine-protein kinase ULK2 chr17 Not Cancer Driver No 1 hippie 132 519 84 84 0
USH1C_ENST00000318024 USH1C Q9Y6N9 Harmonin chr11 Not Cancer Driver No 1 intact, hippie 118 153 45 45 0
USH1G USH1G Q495M9 Usher syndrome type-1G protein chr17 Not Cancer Driver No 1 intact, hippie 82 256 44 44 2
USHBP1 USHBP1 Q8N6Y0 Usher syndrome type-1C protein-binding protein 1 chr19 Not Cancer Driver No 1 intact, hippie 118 583 95 95 0
USP10_ENST00000219473 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 Not Cancer Driver No 1 hippie 92 425 49 49 0
VPS28_ENST00000292510 VPS28 Q9UK41 Vacuolar protein sorting-associated protein 28 homolog chr8 Not Cancer Driver No 1 intact, hippie 28 31 5 5 0
VPS37B VPS37B Q9H9H4 Vacuolar protein sorting-associated protein 37B chr12 Not Cancer Driver No 1 intact, hippie 37 165 23 23 0
VPS52 VPS52 Q8N1B4 Vacuolar protein sorting-associated protein 52 homolog chr6 Not Cancer Driver No 1 hippie 89 36 5 5 0
WASHC1 WASHC1 A8K0Z3 WASH complex subunit 1 chr9 Not Cancer Driver No 1 hippie 6 336 6 6 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 intact, hippie 105 203 10 10 39
WWP1 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 Not Cancer Driver No 1 hippie 139 431 75 75 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
YPEL3_ENST00000566595 YPEL3 P61236 Protein yippee-like 3 chr16 Not Cancer Driver No 1 hippie 13 0 0 0 0
ZBTB8A ZBTB8A Q96BR9 Zinc finger and BTB domain-containing protein 8A chr1 Not Cancer Driver No 1 intact, hippie 47 205 24 24 0
ZMYND12 ZMYND12 Q9H0C1 Zinc finger MYND domain-containing protein 12 chr1 Not Cancer Driver No 1 intact, hippie 56 0 0 0 0
ZNF212 ZNF212 Q9UDV6 Zinc finger protein 212 chr7 Not Cancer Driver No 1 intact, hippie 68 289 34 34 0
ZNF397 ZNF397 Q8NF99 Zinc finger protein 397 chr18 Not Cancer Driver No 1 intact, hippie 49 164 21 21 0
ZSCAN23 ZSCAN23 Q3MJ62 Zinc finger and SCAN domain-containing protein 23 chr6 Not Cancer Driver No 1 hippie 42 164 15 15 0
ZXDC ZXDC Q2QGD7 Zinc finger protein ZXDC chr3 Not Cancer Driver No 1 hippie, biogrid 81 551 49 49 0