Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AAR2_ENST00000320849 | AAR2 | Q9Y312 | Protein AAR2 homolog | chr20 | Not Cancer Driver | No | 1 | hippie | 56 | 28 | 6 | 6 | 0 |
| ABHD11 | ABHD11 | Q8NFV4 | Protein ABHD11 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 73 | 6 | 6 | 0 |
| ACE2 | ACE2 | Q9BYF1 | Angiotensin-converting enzyme 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 104 | 68 | 5 | 5 | 0 |
| ACO2 | ACO2 | Q99798 | Aconitate hydratase, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 94 | 172 | 19 | 19 | 5 |
| ACTC1 | ACTC1 | P68032 | Actin, alpha cardiac muscle 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 114 | 48 | 19 | 19 | 11 |
| AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
| AHSA1 | AHSA1 | O95433 | Activator of 90 kDa heat shock protein ATPase homolog 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 46 | 146 | 17 | 17 | 0 |
| AKR1B1 | AKR1B1 | P15121 | Aldo-keto reductase family 1 member B1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 19 | 1 | 1 | 0 |
| ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 61 | 12 | 12 | 0 |
| APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | Not Cancer Driver | No | 1 | hippie | 34 | 103 | 14 | 14 | 0 |
| ARCN1 | ARCN1 | P48444 | Coatomer subunit delta | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 194 | 24 | 24 | 0 |
| ARFGAP3 | ARFGAP3 | Q9NP61 | ADP-ribosylation factor GTPase-activating protein 3 | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 53 | 321 | 38 | 38 | 0 |
| ASB12 | ASB12 | Q8WXK4 | Ankyrin repeat and SOCS box protein 12 | chrX | Not Cancer Driver | No | 1 | hippie | 77 | 21 | 3 | 3 | 0 |
| ASB3 | ASB3 | Q9Y575 | Ankyrin repeat and SOCS box protein 3 | chr2 | Not Cancer Driver | No | 1 | hippie | 71 | 0 | 0 | 0 | 0 |
| ASS1_ENST00000352480 | ASS1 | P00966 | Argininosuccinate synthase | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 63 | 8 | 8 | 86 |
| ATP6V1A | ATP6V1A | P38606 | V-type proton ATPase catalytic subunit A | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 31 | 2 | 2 | 4 |
| BAG1 | BAG1 | Q99933 | BAG family molecular chaperone regulator 1 | chr9 | Not Cancer Driver | No | 1 | biogrid | 29 | 195 | 9 | 9 | 0 |
| BCAR1_ENST00000162330 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 108 | 677 | 75 | 75 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
| BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
| C11orf54_ENST00000354421 | C11orf54 | Q9H0W9 | Ester hydrolase C11orf54 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 23 | 0 | 0 | 0 |
| CAPG_ENST00000409724 | CAPG | P40121 | Macrophage-capping protein | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 95 | 7 | 7 | 0 |
| CASP10_ENST00000272879 | CASP10 | Q92851 | Caspase-10 | chr2 | Not Cancer Driver | No | 1 | hippie | 57 | 126 | 17 | 17 | 3 |
| CASP8_ENST00000432109 | CASP8 | Q14790 | Caspase-8 | chr2 | Census, Compendium | Yes | 1 | hippie | 142 | 106 | 12 | 12 | 1 |
| CD2AP | CD2AP | Q9Y5K6 | CD2-associated protein | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 456 | 60 | 60 | 0 |
| CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | Census, Compendium | Yes | 1 | hippie | 150 | 400 | 82 | 82 | 5 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 0 |
| CDKL3 | CDKL3 | Q8IVW4 | Cyclin-dependent kinase-like 3 | chr5 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 68 | 278 | 40 | 40 | 0 |
| CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 3 | intact, hippie | 287 | 145 | 18 | 18 | 151 |
| CHMP4C | CHMP4C | Q96CF2 | Charged multivesicular body protein 4c | chr8 | Not Cancer Driver | No | 1 | hippie | 33 | 224 | 31 | 31 | 0 |
| CIC | CIC | Q96RK0 | Protein capicua homolog | chr19 | Census, Compendium | Yes | 1 | hippie | 276 | 1550 | 266 | 266 | 0 |
| CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
| CLIC1_ENST00000375779 | CLIC1 | O00299 | Chloride intracellular channel protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 27 | 5 | 5 | 0 |
| CLIC4 | CLIC4 | Q9Y696 | Chloride intracellular channel protein 4 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 49 | 4 | 4 | 0 |
| COA7 | COA7 | Q96BR5 | Cytochrome c oxidase assembly factor 7 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 39 | 7 | 7 | 2 |
| COX15 | COX15 | Q7KZN9 | Cytochrome c oxidase assembly protein COX15 homolog | chr10 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 48 | 0 | 0 | 0 | 2 |
| COX4I1 | COX4I1 | P13073 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 5 | 1 | 1 | 1 |
| CRYZ_ENST00000340866 | CRYZ | Q08257 | Quinone oxidoreductase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 0 | 0 | 0 | 0 |
| CTBP1 | CTBP1 | Q13363 | C-terminal-binding protein 1 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 42 | 123 | 9 | 9 | 1 |
| CTBP2_ENST00000494626 | CTBP2 | P56545 | C-terminal-binding protein 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 48 | 94 | 4 | 4 | 0 |
| CUL1_ENST00000602748 | CUL1 | Q13616 | Cullin-1 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 151 | 65 | 9 | 9 | 0 |
| CUL4A | CUL4A | Q13619 | Cullin-4A | chr13 | Not Cancer Driver | No | 1 | intact, hippie | 64 | 102 | 2 | 2 | 0 |
| CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | Not Cancer Driver | No | 1 | hippie | 188 | 372 | 41 | 41 | 3 |
| DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 34 | 181 | 23 | 23 | 0 |
| DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 67 | 17 | 0 | 0 | 10 |
| DNM1L_ENST00000549701 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 212 | 23 | 23 | 7 |
| DUSP13_ENST00000472493 | DUSP13 | Q9UII6 | Dual specificity protein phosphatase 13 isoform B | chr10 | Not Cancer Driver | No | 1 | hippie | 45 | 16 | 1 | 1 | 0 |
| DUSP4 | DUSP4 | Q13115 | Dual specificity protein phosphatase 4 | chr8 | Not Cancer Driver | No | 1 | hippie | 43 | 63 | 9 | 9 | 0 |
| DYRK2 | DYRK2 | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 77 | 294 | 39 | 39 | 0 |
| ECI1 | ECI1 | P42126 | Enoyl-CoA delta isomerase 1, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 14 | 0 | 0 | 0 |
| EFTUD2 | EFTUD2 | Q15029 | 116 kDa U5 small nuclear ribonucleoprotein component | chr17 | Compendium | Yes | 1 | hippie | 132 | 179 | 30 | 30 | 3 |
| EMC1 | EMC1 | Q8N766 | ER membrane protein complex subunit 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 107 | 59 | 6 | 6 | 2 |
| EMC4 | EMC4 | Q5J8M3 | ER membrane protein complex subunit 4 | chr15 | Not Cancer Driver | No | 1 | hippie | 15 | 17 | 2 | 2 | 0 |
| ENO1 | ENO1 | P06733 | Alpha-enolase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 21 | 2 | 2 | 0 |
| ENOPH1 | ENOPH1 | Q9UHY7 | Enolase-phosphatase E1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 14 | 2 | 2 | 0 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
| ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
| FBP1_ENST00000375326 | FBP1 | P09467 | Fructose-1,6-bisphosphatase 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 33 | 19 | 0 | 0 | 4 |
| FDX1 | FDX1 | P10109 | Adrenodoxin, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 61 | 2 | 2 | 0 |
| FDX2 | FDX2 | Q6P4F2 | Ferredoxin-2, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 26 | 102 | 14 | 14 | 1 |
| FN1 | FN1 | P02751 | Fibronectin | chr2 | Compendium | Yes | 1 | intact, hippie | 394 | 1243 | 185 | 185 | 8 |
| FURIN_ENST00000610579 | FURIN | P09958 | Furin | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 93 | 283 | 35 | 35 | 0 |
| FXN | FXN | Q16595 | Frataxin, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 73 | 0 | 0 | 8 |
| G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 85 | 352 | 65 | 65 | 0 |
| GABARAPL1_ENST00000545887 | GABARAPL1 | Q9H0R8 | Gamma-aminobutyric acid receptor-associated protein-like 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 19 | 10 | 1 | 1 | 0 |
| GABARAPL2 | GABARAPL2 | P60520 | Gamma-aminobutyric acid receptor-associated protein-like 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 11 | 2 | 1 | 1 | 0 |
| GCSH | GCSH | P23434 | Glycine cleavage system H protein, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 25 | 0 | 0 | 0 |
| GLO1 | GLO1 | Q04760 | Lactoylglutathione lyase | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 46 | 7 | 7 | 0 |
| GLRX5 | GLRX5 | Q86SX6 | Glutaredoxin-related protein 5, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 23 | 0 | 0 | 2 |
| GPI_ENST00000644934 | GPI | P06744 | Glucose-6-phosphate isomerase | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 77 | 73 | 11 | 11 | 24 |
| GPX4_ENST00000616066 | GPX4 | P36969 | Phospholipid hydroperoxide glutathione peroxidase | chr19 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 14 | 0 | 0 | 0 | 0 |
| GRHPR | GRHPR | Q9UBQ7 | Glyoxylate reductase/hydroxypyruvate reductase | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 31 | 36 | 4 | 4 | 0 |
| GSTO1 | GSTO1 | P78417 | Glutathione S-transferase omega-1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 18 | 1 | 1 | 0 |
| GSTP1_ENST00000642444 | GSTP1 | P09211 | Glutathione S-transferase P | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 32 | 0 | 0 | 0 | 0 |
| GSTZ1 | GSTZ1 | O43708 | Maleylacetoacetate isomerase | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 19 | 2 | 2 | 2 |
| GUK1_ENST00000366718 | GUK1 | Q16774 | Guanylate kinase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 71 | 9 | 9 | 0 |
| H2AFX | H2AX | P16104 | Histone H2AX | chr11 | Not Cancer Driver | No | 1 | intact | 20 | 68 | 10 | 10 | 0 |
| HDAC5_ENST00000586802 | HDAC5 | Q9UQL6 | Histone deacetylase 5 | chr17 | Not Cancer Driver | No | 1 | hippie | 118 | 718 | 73 | 73 | 0 |
| HINT1 | HINT1 | P49773 | Adenosine 5'-monophosphoramidase HINT1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 6 | 0 | 0 | 6 |
| HINT2 | HINT2 | Q9BX68 | Adenosine 5'-monophosphoramidase HINT2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 29 | 2 | 2 | 0 |
| HNF4G_ENST00000354370 | HNF4G | Q14541 | Hepatocyte nuclear factor 4-gamma | chr8 | Not Cancer Driver | No | 1 | hippie | 122 | 96 | 29 | 29 | 0 |
| HNRNPL | HNRNPL | P14866 | Heterogeneous nuclear ribonucleoprotein L | chr19 | Not Cancer Driver | No | 1 | hippie | 89 | 283 | 29 | 29 | 0 |
| HSD17B10 | HSD17B10 | Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | chrX | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 27 | 15 | 3 | 3 | 11 |
| HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie | 149 | 251 | 52 | 52 | 0 |
| HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 118 | 8 | 8 | 20 |
| HUWE1_ENST00000262854 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | Not Cancer Driver | No | 1 | hippie | 669 | 2091 | 329 | 329 | 21 |
| IDH2 | IDH2 | P48735 | Isocitrate dehydrogenase [NADP], mitochondrial | chr15 | Census, Compendium | Yes | 1 | hippie, biogrid | 74 | 59 | 1 | 1 | 7 |
| INS | INS | P01308 | Insulin | chr11 | Not Cancer Driver | No | 1 | hippie | 15 | 5 | 1 | 1 | 22 |
| ISG15 | ISG15 | P05161 | Ubiquitin-like protein ISG15 | chr1 | Not Cancer Driver | No | 1 | hippie | 12 | 24 | 2 | 2 | 0 |
| ITGA4 | ITGA4 | P13612 | Integrin alpha-4 | chr2 | Not Cancer Driver | No | 1 | hippie | 254 | 97 | 27 | 27 | 0 |
| JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
| KCNMA1 | KCNMA1 | Q12791 | Calcium-activated potassium channel subunit alpha-1 | chr10 | Not Cancer Driver | No | 1 | intact | 222 | 225 | 39 | 39 | 5 |
| KIAA0556 | KATNIP | O60303 | Katanin-interacting protein | chr16 | Not Cancer Driver | No | 1 | intact | 240 | 982 | 137 | 137 | 0 |
| KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
| KIF23 | KIF23 | Q02241 | Kinesin-like protein KIF23 | chr15 | Not Cancer Driver | No | 1 | hippie | 102 | 559 | 62 | 62 | 0 |
| LACTB2 | LACTB2 | Q53H82 | Endoribonuclease LACTB2 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 21 | 1 | 1 | 0 |
| LAP3 | LAP3 | P28838 | Cytosol aminopeptidase | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 99 | 14 | 14 | 0 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | Not Cancer Driver | No | 1 | hippie | 54 | 65 | 16 | 16 | 0 |
| LYPLA1 | LYPLA1 | O75608 | Acyl-protein thioesterase 1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 12 | 2 | 2 | 0 |
| MAP1LC3A_ENST00000397709 | MAP1LC3A | Q9H492 | Microtubule-associated proteins 1A/1B light chain 3A | chr20 | Not Cancer Driver | No | 1 | hippie | 22 | 24 | 1 | 1 | 0 |
| MAP2K1 | MAP2K1 | Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | chr15 | Census, Compendium | Yes | 1 | hippie | 94 | 96 | 24 | 24 | 6 |
| MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 104 | 333 | 66 | 66 | 6 |
| MAPK13 | MAPK13 | O15264 | Mitogen-activated protein kinase 13 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 51 | 50 | 15 | 15 | 0 |
| MAPK1_ENST00000398822 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | Census, Compendium | Yes | 1 | hippie | 62 | 2 | 0 | 0 | 7 |
| MDH1_ENST00000233114 | MDH1 | P40925 | Malate dehydrogenase, cytoplasmic | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 18 | 2 | 2 | 1 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
| MTPN | MTPN | P58546 | Myotrophin | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 11 | 3 | 3 | 0 |
| MYLK | MYLK | Q15746 | Myosin light chain kinase, smooth muscle | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 343 | 957 | 184 | 184 | 3 |
| MYLK4 | MYLK4 | Q86YV6 | Myosin light chain kinase family member 4 | chr6 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 67 | 77 | 14 | 14 | 0 |
| NAA40 | NAA40 | Q86UY6 | N-alpha-acetyltransferase 40 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 30 | 3 | 3 | 0 |
| NCF2 | NCF2 | P19878 | Neutrophil cytosol factor 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 97 | 183 | 34 | 34 | 14 |
| NDUFAB1_ENST00000007516 | NDUFAB1 | O14561 | Acyl carrier protein, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 0 | 0 | 0 | 0 |
| NEDD8 | NEDD8 | Q15843 | NEDD8 | chr14 | Not Cancer Driver | No | 1 | hippie | 10 | 36 | 5 | 5 | 0 |
| NEK7 | NEK7 | Q8TDX7 | Serine/threonine-protein kinase Nek7 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 35 | 23 | 0 | 0 | 0 |
| NENF | NENF | Q9UMX5 | Neudesin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 98 | 7 | 7 | 0 |
| NHLRC2 | NHLRC2 | Q8NBF2 | NHL repeat-containing protein 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 74 | 103 | 12 | 12 | 0 |
| NIT2 | NIT2 | Q9NQR4 | Omega-amidase NIT2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 0 | 0 | 0 | 0 |
| NME1_ENST00000393196 | NME1 | P15531 | Nucleoside diphosphate kinase A | chr17 | Not Cancer Driver | No | 1 | hippie | 11 | 10 | 0 | 0 | 0 |
| NPM1 | NPM1 | P06748 | Nucleophosmin | chr5 | Census, Compendium | Yes | 1 | hippie | 29 | 249 | 22 | 22 | 0 |
| NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
| NR4A1_ENST00000394825 | NR4A1 | P22736 | Nuclear receptor subfamily 4 group A member 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 62 | 252 | 24 | 24 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
| NUDCD2 | NUDCD2 | Q8WVJ2 | NudC domain-containing protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 12 | 39 | 6 | 6 | 0 |
| ORM2 | ORM2 | P19652 | Alpha-1-acid glycoprotein 2 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 38 | 22 | 2 | 2 | 0 |
| OTUB1_ENST00000428192 | OTUB1 | Q96FW1 | Ubiquitin thioesterase OTUB1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 33 | 2 | 2 | 0 |
| OXCT1 | OXCT1 | P55809 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 39 | 5 | 5 | 11 |
| PAGE4_ENST00000376141 | PAGE4 | O60829 | P antigen family member 4 | chrX | Not Cancer Driver | No | 1 | hippie | 20 | 102 | 20 | 20 | 0 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 11 | 30 | 0 | 0 | 5 |
| PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 120 | 461 | 39 | 39 | 0 |
| PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | Not Cancer Driver | No | 2 | intact, hippie | 30 | 22 | 3 | 3 | 1 |
| PDP1_ENST00000297598 | PDP1 | Q9P0J1 | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 96 | 9 | 9 | 0 |
| PFAS | PFAS | O15067 | Phosphoribosylformylglycinamidine synthase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 380 | 36 | 36 | 0 |
| PGLS | PGLS | O95336 | 6-phosphogluconolactonase | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 36 | 4 | 4 | 0 |
| PGM1_ENST00000371084 | PGM1 | P36871 | Phosphoglucomutase-1 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 62 | 31 | 3 | 3 | 13 |
| PHOSPHO1_ENST00000310544 | PHOSPHO1 | Q8TCT1 | Phosphoethanolamine/phosphocholine phosphatase | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 14 | 18 | 0 | 0 | 0 |
| PIH1D1 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 157 | 13 | 13 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 57 | 99 | 13 | 13 | 23 |
| PITRM1_ENST00000224949 | PITRM1 | Q5JRX3 | Presequence protease, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 122 | 220 | 26 | 26 | 2 |
| PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | Not Cancer Driver | No | 1 | intact | 113 | 375 | 35 | 35 | 10 |
| PKM_ENST00000335181 | PKM | P14618 | Pyruvate kinase PKM | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 58 | 13 | 13 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PMAIP1 | PMAIP1 | Q13794 | Phorbol-12-myristate-13-acetate-induced protein 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 2 | 23 | 1 | 1 | 0 |
| PMPCA | PMPCA | Q10713 | Mitochondrial-processing peptidase subunit alpha | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 23 | 3 | 3 | 4 |
| PPARD_ENST00000360694 | PPARD | Q03181 | Peroxisome proliferator-activated receptor delta | chr6 | Not Cancer Driver | No | 1 | hippie | 72 | 69 | 7 | 7 | 0 |
| PPTC7 | PPTC7 | Q8NI37 | Protein phosphatase PTC7 homolog | chr12 | Not Cancer Driver | No | 1 | hippie | 32 | 36 | 2 | 2 | 0 |
| PRDX1_ENST00000319248 | PRDX1 | Q06830 | Peroxiredoxin-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 40 | 5 | 5 | 0 |
| PRDX2 | PRDX2 | P32119 | Peroxiredoxin-2 | chr19 | Not Cancer Driver | No | 3 | hippie, biogrid | 24 | 30 | 4 | 4 | 0 |
| PRDX5 | PRDX5 | P30044 | Peroxiredoxin-5, mitochondrial | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 22 | 0 | 0 | 0 | 0 |
| PRDX6 | PRDX6 | P30041 | Peroxiredoxin-6 | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 46 | 13 | 4 | 4 | 0 |
| PRKCZ | PRKCZ | Q05513 | Protein kinase C zeta type | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 70 | 116 | 11 | 11 | 0 |
| PRKD2_ENST00000291281 | PRKD2 | Q9BZL6 | Serine/threonine-protein kinase D2 | chr19 | Compendium | Yes | 1 | hippie, biogrid | 118 | 246 | 34 | 34 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
| PRPF8 | PRPF8 | Q6P2Q9 | Pre-mRNA-processing-splicing factor 8 | chr17 | Not Cancer Driver | No | 1 | hippie | 255 | 225 | 26 | 26 | 8 |
| PSMD8 | PSMD8 | P48556 | 26S proteasome non-ATPase regulatory subunit 8 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 20 | 78 | 2 | 2 | 0 |
| PTGR1_ENST00000309195 | PTGR1 | Q14914 | Prostaglandin reductase 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 12 | 1 | 1 | 0 |
| PTRHD1 | PTRHD1 | Q6GMV3 | Putative peptidyl-tRNA hydrolase PTRHD1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 22 | 2 | 2 | 0 |
| RAD52 | RAD52 | P43351 | DNA repair protein RAD52 homolog | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 41 | 251 | 30 | 30 | 0 |
| RANGAP1_ENST00000356244 | RANGAP1 | P46060 | Ran GTPase-activating protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 159 | 17 | 17 | 0 |
| RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | Census, Compendium | Yes | 1 | hippie | 70 | 167 | 14 | 14 | 0 |
| RCAN3_ENST00000538532 | RCAN3 | Q9UKA8 | Calcipressin-3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 121 | 18 | 18 | 0 |
| RDX_ENST00000343115 | RDX | P35241 | Radixin | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 297 | 37 | 37 | 1 |
| RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie, biogrid | 99 | 46 | 13 | 13 | 2 |
| RIN3 | RIN3 | Q8TB24 | Ras and Rab interactor 3 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 137 | 417 | 61 | 61 | 0 |
| RIPK4_ENST00000352483 | RIPK4 | P57078 | Receptor-interacting serine/threonine-protein kinase 4 | chr21 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 119 | 232 | 34 | 34 | 3 |
| RYBP | RYBP | Q8N488 | RING1 and YY1-binding protein | chr3 | Not Cancer Driver | No | 1 | hippie | 37 | 214 | 37 | 37 | 0 |
| S100A9 | S100A9 | P06702 | Protein S100-A9 | chr1 | Not Cancer Driver | No | 1 | hippie | 18 | 76 | 7 | 7 | 0 |
| SCPEP1 | SCPEP1 | Q9HB40 | Retinoid-inducible serine carboxypeptidase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 1 | 0 | 0 | 0 |
| SDHB | SDHB | P21912 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | chr1 | Census | Yes | 1 | hippie, biogrid | 37 | 17 | 3 | 3 | 23 |
| SERPINA5_ENST00000554276 | SERPINA5 | P05154 | Plasma serine protease inhibitor | chr14 | Not Cancer Driver | No | 1 | hippie | 103 | 24 | 17 | 17 | 0 |
| SERPINB5 | SERPINB5 | P36952 | Serpin B5 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 50 | 7 | 7 | 0 |
| SFTPA1_ENST00000398636 | SFTPA1 | Q8IWL2 | Pulmonary surfactant-associated protein A1 | chr10 | Not Cancer Driver | No | 1 | hippie | 41 | 171 | 33 | 33 | 3 |
| SGK3_ENST00000521198 | SGK3 | Q96BR1 | Serine/threonine-protein kinase Sgk3 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 70 | 10 | 10 | 0 |
| SNAI1 | SNAI1 | O95863 | Zinc finger protein SNAI1 | chr20 | Not Cancer Driver | No | 1 | hippie | 52 | 97 | 11 | 11 | 0 |
| SOAT1 | SOAT1 | P35610 | Sterol O-acyltransferase 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 73 | 49 | 4 | 4 | 0 |
| SOD1 | SOD1 | P00441 | Superoxide dismutase [Cu-Zn] | chr21 | Not Cancer Driver | No | 2 | hippie, biogrid | 16 | 93 | 9 | 9 | 79 |
| SPR | SPR | P35270 | Sepiapterin reductase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 19 | 4 | 4 | 2 |
| SSU72 | SSU72 | Q9NP77 | RNA polymerase II subunit A C-terminal domain phosphatase SSU72 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 65 | 3 | 3 | 0 |
| STAU1 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 77 | 456 | 63 | 63 | 0 |
| STH | STH | Q8IWL8 | Saitohin | chr17 | Not Cancer Driver | No | 1 | hippie | 13 | 55 | 5 | 5 | 0 |
| SUCLG2_ENST00000307227 | SUCLG2 | Q96I99 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 12 | 2 | 2 | 0 |
| SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
| SUMO4 | SUMO4 | Q6EEV6 | Small ubiquitin-related modifier 4 | chr6 | Not Cancer Driver | No | 1 | hippie | 7 | 69 | 4 | 4 | 0 |
| TBCA_ENST00000380377 | TBCA | O75347 | Tubulin-specific chaperone A | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 8 | 30 | 1 | 1 | 0 |
| TERF1 | TERF1 | P54274 | Telomeric repeat-binding factor 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 63 | 220 | 34 | 34 | 0 |
| TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 28 | 310 | 16 | 16 | 0 |
| TFCP2 | TFCP2 | Q12800 | Alpha-globin transcription factor CP2 | chr12 | Not Cancer Driver | No | 1 | hippie | 68 | 169 | 23 | 23 | 0 |
| TIFAB | TIFAB | Q6ZNK6 | TRAF-interacting protein with FHA domain-containing protein B | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 32 | 26 | 7 | 7 | 0 |
| TIMM9_ENST00000555593 | TIMM9 | Q9Y5J7 | Mitochondrial import inner membrane translocase subunit Tim9 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 9 | 8 | 1 | 1 | 0 |
| TMED10 | TMED10 | P49755 | Transmembrane emp24 domain-containing protein 10 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 15 | 3 | 3 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
| TPI1_ENST00000396705 | TPI1 | P60174 | Triosephosphate isomerase | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 40 | 15 | 2 | 2 | 7 |
| TRIM14 | TRIM14 | Q14142 | Tripartite motif-containing protein 14 | chr9 | Not Cancer Driver | No | 1 | hippie | 36 | 93 | 7 | 7 | 0 |
| TXNL1_ENST00000590954 | TXNL1 | O43396 | Thioredoxin-like protein 1 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 89 | 4 | 4 | 0 |
| UBE2M | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 32 | 6 | 6 | 0 |
| UCHL1 | UCHL1 | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 34 | 7 | 7 | 4 |
| UCHL5 | UCHL5 | Q9Y5K5 | Ubiquitin carboxyl-terminal hydrolase isozyme L5 | chr1 | Not Cancer Driver | No | 1 | hippie | 33 | 41 | 7 | 7 | 0 |
| UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 141 | 24 | 24 | 0 |
| VCAM1 | VCAM1 | P19320 | Vascular cell adhesion protein 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 188 | 110 | 28 | 28 | 0 |
| VDAC1_ENST00000395047 | VDAC1 | P21796 | Voltage-dependent anion-selective channel protein 1 | chr5 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 38 | 36 | 4 | 4 | 0 |
| VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
| WDR1 | WDR1 | O75083 | WD repeat-containing protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 30 | 7 | 7 | 2 |
| WDR5 | WDR5 | P61964 | WD repeat-containing protein 5 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 35 | 3 | 3 | 0 |
| YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | Not Cancer Driver | No | 1 | hippie | 51 | 489 | 49 | 49 | 0 |
| YWHAE | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | Census | Yes | 1 | intact, hippie | 32 | 41 | 3 | 3 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|