Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACLY_ENST00000590151 | ACLY | P53396 | ATP-citrate synthase | chr17 | Not Cancer Driver | No | 1 | hippie | 120 | 114 | 12 | 12 | 0 |
ACRV1 | ACRV1 | P26436 | Acrosomal protein SP-10 | chr11 | Not Cancer Driver | No | 1 | hippie | 32 | 169 | 20 | 20 | 0 |
ACTA2 | ACTA2 | P62736 | Actin, aortic smooth muscle | chr10 | Not Cancer Driver | No | 1 | hippie | 50 | 39 | 4 | 4 | 17 |
ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 112 | 43 | 5 | 5 | 5 |
ACTN1_ENST00000193403 | ACTN1 | P12814 | Alpha-actinin-1 | chr14 | Not Cancer Driver | No | 1 | hippie | 108 | 195 | 30 | 30 | 6 |
ACTR1A | ACTR1A | P61163 | Alpha-centractin | chr10 | Not Cancer Driver | No | 1 | hippie | 47 | 14 | 0 | 0 | 0 |
AGO2 | AGO2 | Q9UKV8 | Protein argonaute-2 | chr8 | Not Cancer Driver | No | 1 | hippie | 126 | 141 | 15 | 15 | 11 |
AHNAK | AHNAK | Q09666 | Neuroblast differentiation-associated protein AHNAK | chr11 | Not Cancer Driver | No | 1 | hippie | 805 | 5777 | 794 | 794 | 0 |
ANXA2_ENST00000396024 | ANXA2 | P07355 | Annexin A2 | chr15 | Not Cancer Driver | No | 1 | hippie | 49 | 20 | 4 | 4 | 0 |
APAF1 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 127 | 17 | 1 | 1 | 0 |
ARID3B | ARID3B | Q8IVW6 | AT-rich interactive domain-containing protein 3B | chr15 | Not Cancer Driver | No | 1 | hippie | 72 | 394 | 57 | 57 | 0 |
ARMC8_ENST00000469044 | ARMC8 | Q8IUR7 | Armadillo repeat-containing protein 8 | chr3 | Not Cancer Driver | No | 1 | hippie | 71 | 7 | 0 | 0 | 0 |
ASB3 | ASB3 | Q9Y575 | Ankyrin repeat and SOCS box protein 3 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 71 | 0 | 0 | 0 | 0 |
ATL1 | ATL1 | Q8WXF7 | Atlastin-1 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 72 | 55 | 12 | 12 | 19 |
ATP1A1_ENST00000295598 | ATP1A1 | P05023 | Sodium/potassium-transporting ATPase subunit alpha-1 | chr1 | Census | Yes | 1 | hippie | 115 | 115 | 16 | 16 | 6 |
ATP2A2 | ATP2A2 | P16615 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 136 | 78 | 14 | 14 | 41 |
ATP5F1A_ENST00000282050 | ATP5F1A | P25705 | ATP synthase subunit alpha, mitochondrial | chr18 | Not Cancer Driver | No | 1 | hippie | 66 | 23 | 5 | 5 | 2 |
ATP5F1B | ATP5F1B | P06576 | ATP synthase subunit beta, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 60 | 85 | 8 | 8 | 0 |
ATP5PO | ATP5PO | P48047 | ATP synthase subunit O, mitochondrial | chr21 | Not Cancer Driver | No | 1 | hippie | 19 | 9 | 2 | 2 | 0 |
BAG6 | BAG6 | P46379 | Large proline-rich protein BAG6 | chr6 | Not Cancer Driver | No | 1 | hippie | 98 | 861 | 79 | 79 | 0 |
BCKDHB | BCKDHB | P21953 | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie | 47 | 23 | 3 | 3 | 5 |
BSG | BSG | P35613 | Basigin | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 123 | 17 | 17 | 0 |
CAND1 | CAND1 | Q86VP6 | Cullin-associated NEDD8-dissociated protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 161 | 88 | 7 | 7 | 0 |
CANX_ENST00000504734 | CANX | P27824 | Calnexin | chr5 | Not Cancer Driver | No | 1 | hippie | 65 | 334 | 38 | 38 | 0 |
CAPZB_ENST00000375142 | CAPZB | P47756 | F-actin-capping protein subunit beta | chr1 | Not Cancer Driver | No | 1 | hippie | 33 | 66 | 3 | 3 | 0 |
CARM1 | CARM1 | Q86X55 | Histone-arginine methyltransferase CARM1 | chr19 | Not Cancer Driver | No | 1 | hippie | 62 | 102 | 10 | 10 | 0 |
CCAR2 | CCAR2 | Q8N163 | Cell cycle and apoptosis regulator protein 2 | chr8 | Not Cancer Driver | No | 1 | hippie | 102 | 528 | 62 | 62 | 0 |
CCT2 | CCT2 | P78371 | T-complex protein 1 subunit beta | chr12 | Not Cancer Driver | No | 1 | hippie | 63 | 46 | 3 | 3 | 0 |
CCT3 | CCT3 | P49368 | T-complex protein 1 subunit gamma | chr1 | Not Cancer Driver | No | 1 | hippie | 71 | 95 | 12 | 12 | 0 |
CCT4 | CCT4 | P50991 | T-complex protein 1 subunit delta | chr2 | Not Cancer Driver | No | 1 | hippie | 51 | 92 | 2 | 2 | 0 |
CCT5 | CCT5 | P48643 | T-complex protein 1 subunit epsilon | chr5 | Not Cancer Driver | No | 1 | hippie | 83 | 72 | 10 | 10 | 1 |
CCT6A | CCT6A | P40227 | T-complex protein 1 subunit zeta | chr7 | Not Cancer Driver | No | 1 | hippie | 66 | 5 | 1 | 1 | 0 |
CCT7 | CCT7 | Q99832 | T-complex protein 1 subunit eta | chr2 | Not Cancer Driver | No | 1 | hippie | 59 | 36 | 6 | 6 | 0 |
CCT8 | CCT8 | P50990 | T-complex protein 1 subunit theta | chr21 | Not Cancer Driver | No | 1 | hippie | 41 | 36 | 2 | 2 | 0 |
CHGB | CHGB | P05060 | Secretogranin-1 | chr20 | Not Cancer Driver | No | 1 | hippie | 174 | 575 | 153 | 153 | 0 |
CHP1 | CHP1 | Q99653 | Calcineurin B homologous protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 27 | 70 | 12 | 12 | 0 |
CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
CLGN_ENST00000414773 | CLGN | O14967 | Calmegin | chr4 | Not Cancer Driver | No | 1 | hippie | 86 | 255 | 36 | 36 | 0 |
CLTC_ENST00000269122 | CLTC | Q00610 | Clathrin heavy chain 1 | chr17 | Census, Compendium | Yes | 1 | hippie | 190 | 71 | 6 | 6 | 1 |
CPT1A_ENST00000539743 | CPT1A | P50416 | Carnitine O-palmitoyltransferase 1, liver isoform | chr11 | Not Cancer Driver | No | 1 | hippie | 144 | 62 | 10 | 10 | 15 |
CRIP2_ENST00000329146 | CRIP2 | P52943 | Cysteine-rich protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie | 15 | 68 | 3 | 3 | 0 |
CRMP1_ENST00000397890 | CRMP1 | Q14194 | Dihydropyrimidinase-related protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 122 | 96 | 15 | 15 | 0 |
CTNND1 | CTNND1 | O60716 | Catenin delta-1 | chr11 | Census | Yes | 1 | hippie | 154 | 570 | 83 | 83 | 0 |
CTSD | CTSD | P07339 | Cathepsin D | chr11 | Not Cancer Driver | No | 1 | hippie | 57 | 6 | 1 | 1 | 2 |
DBH | DBH | P09172 | Dopamine beta-hydroxylase | chr9 | Not Cancer Driver | No | 1 | hippie | 125 | 71 | 17 | 17 | 3 |
DBN1_ENST00000309007 | DBN1 | Q16643 | Drebrin | chr5 | Not Cancer Driver | No | 1 | hippie | 84 | 510 | 73 | 73 | 0 |
DBT | DBT | P11182 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 64 | 81 | 11 | 11 | 3 |
DDOST_ENST00000375048 | DDOST | P39656 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 13 | 3 | 3 | 1 |
DDX1 | DDX1 | Q92499 | ATP-dependent RNA helicase DDX1 | chr2 | Not Cancer Driver | No | 1 | hippie | 82 | 91 | 15 | 15 | 0 |
DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | Census, Compendium | Yes | 1 | hippie | 133 | 301 | 47 | 47 | 18 |
DHX9 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | Compendium | Yes | 1 | hippie | 182 | 331 | 42 | 42 | 0 |
DLAT | DLAT | P10515 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 63 | 294 | 42 | 42 | 0 |
DNAJA1 | DNAJA1 | P31689 | DnaJ homolog subfamily A member 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 37 | 153 | 16 | 16 | 0 |
DNAJB1 | DNAJB1 | P25685 | DnaJ homolog subfamily B member 1 | chr19 | Census, Compendium | Yes | 1 | hippie | 35 | 196 | 26 | 26 | 0 |
DNAJB11_ENST00000265028 | DNAJB11 | Q9UBS4 | DnaJ homolog subfamily B member 11 | chr3 | Not Cancer Driver | No | 1 | hippie | 52 | 141 | 21 | 21 | 2 |
DNAJC10 | DNAJC10 | Q8IXB1 | DnaJ homolog subfamily C member 10 | chr2 | Not Cancer Driver | No | 1 | hippie | 110 | 36 | 3 | 3 | 0 |
DNM1L_ENST00000549701 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | Not Cancer Driver | No | 1 | hippie | 67 | 212 | 23 | 23 | 7 |
DOCK7_ENST00000635253 | DOCK7 | Q96N67 | Dedicator of cytokinesis protein 7 | chr1 | Not Cancer Driver | No | 1 | hippie | 262 | 454 | 53 | 53 | 0 |
DYNC1H1 | DYNC1H1 | Q14204 | Cytoplasmic dynein 1 heavy chain 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 505 | 495 | 62 | 62 | 21 |
DYNLL1_ENST00000242577 | DYNLL1 | P63167 | Dynein light chain 1, cytoplasmic | chr12 | Not Cancer Driver | No | 1 | hippie | 9 | 0 | 0 | 0 | 0 |
EEF1A2 | EEF1A2 | Q05639 | Elongation factor 1-alpha 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 74 | 121 | 17 | 17 | 3 |
EEF1G | EEF1G | P26641 | Elongation factor 1-gamma | chr11 | Not Cancer Driver | No | 1 | hippie | 44 | 66 | 5 | 5 | 0 |
EEF2 | EEF2 | P13639 | Elongation factor 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 111 | 78 | 14 | 14 | 1 |
EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
ELAVL4_ENST00000371821 | ELAVL4 | P26378 | ELAV-like protein 4 | chr1 | Not Cancer Driver | No | 1 | hippie | 118 | 117 | 34 | 34 | 0 |
ENO1 | ENO1 | P06733 | Alpha-enolase | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 21 | 2 | 2 | 0 |
ENO2 | ENO2 | P09104 | Gamma-enolase | chr12 | Not Cancer Driver | No | 1 | hippie | 48 | 12 | 2 | 2 | 0 |
ERLEC1 | ERLEC1 | Q96DZ1 | Endoplasmic reticulum lectin 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 134 | 17 | 17 | 0 |
FASN | FASN | P49327 | Fatty acid synthase | chr17 | Not Cancer Driver | No | 1 | hippie | 291 | 309 | 42 | 42 | 0 |
FBXO6 | FBXO6 | Q9NRD1 | F-box only protein 6 | chr1 | Not Cancer Driver | No | 1 | hippie | 31 | 27 | 3 | 3 | 0 |
FTH1_ENST00000620041 | FTH1 | P02794 | Ferritin heavy chain | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 57 | 7 | 7 | 0 |
FUS | FUS | P35637 | RNA-binding protein FUS | chr16 | Census | Yes | 1 | hippie | 51 | 524 | 51 | 51 | 20 |
G3BP2_ENST00000395719 | G3BP2 | Q9UN86 | Ras GTPase-activating protein-binding protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 64 | 384 | 53 | 53 | 0 |
GAPDH | GAPDH | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | chr12 | Not Cancer Driver | No | 1 | hippie | 39 | 24 | 3 | 3 | 0 |
GCN1 | GCN1 | Q92616 | eIF-2-alpha kinase activator GCN1 | chr12 | Not Cancer Driver | No | 1 | hippie | 327 | 117 | 16 | 16 | 0 |
GDI2 | GDI2 | P50395 | Rab GDP dissociation inhibitor beta | chr10 | Not Cancer Driver | No | 1 | hippie | 49 | 23 | 2 | 2 | 0 |
GIT1_ENST00000225394 | GIT1 | Q9Y2X7 | ARF GTPase-activating protein GIT1 | chr17 | Not Cancer Driver | No | 1 | hippie | 67 | 434 | 42 | 42 | 0 |
GNAQ | GNAQ | P50148 | Guanine nucleotide-binding protein G(q) subunit alpha | chr9 | Census, Compendium | Yes | 1 | intact, hippie | 57 | 14 | 1 | 1 | 1 |
GSTP1_ENST00000642444 | GSTP1 | P09211 | Glutathione S-transferase P | chr11 | Not Cancer Driver | No | 1 | hippie | 32 | 0 | 0 | 0 | 0 |
GTF2I | GTF2I | P78347 | General transcription factor II-I | chr7 | Compendium | Yes | 1 | hippie | 74 | 365 | 27 | 27 | 0 |
HK1_ENST00000359426 | HK1 | P19367 | Hexokinase-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 127 | 75 | 16 | 16 | 6 |
HNRNPA1 | HNRNPA1 | P09651 | Heterogeneous nuclear ribonucleoprotein A1 | chr12 | Not Cancer Driver | No | 1 | hippie | 70 | 290 | 58 | 58 | 4 |
HNRNPA1L2 | HNRNPA1L2 | Q32P51 | Heterogeneous nuclear ribonucleoprotein A1-like 2 | chr13 | Not Cancer Driver | No | 1 | hippie | 29 | 235 | 23 | 23 | 0 |
HNRNPA2B1 | HNRNPA2B1 | P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 | chr7 | Census, Compendium | Yes | 1 | hippie | 68 | 255 | 41 | 41 | 0 |
HNRNPAB | HNRNPAB | Q99729 | Heterogeneous nuclear ribonucleoprotein A/B | chr5 | Not Cancer Driver | No | 1 | hippie | 31 | 202 | 11 | 11 | 0 |
HNRNPF_ENST00000356053 | HNRNPF | P52597 | Heterogeneous nuclear ribonucleoprotein F | chr10 | Not Cancer Driver | No | 1 | hippie | 65 | 105 | 18 | 18 | 0 |
HNRNPH1 | HNRNPH1 | P31943 | Heterogeneous nuclear ribonucleoprotein H | chr5 | Not Cancer Driver | No | 1 | hippie | 51 | 169 | 29 | 29 | 0 |
HNRNPH2 | HNRNPH2 | P55795 | Heterogeneous nuclear ribonucleoprotein H2 | chrX | Not Cancer Driver | No | 1 | hippie | 73 | 168 | 34 | 34 | 3 |
HNRNPH3 | HNRNPH3 | P31942 | Heterogeneous nuclear ribonucleoprotein H3 | chr10 | Not Cancer Driver | No | 1 | hippie | 42 | 188 | 18 | 18 | 0 |
HNRNPK_ENST00000351839 | HNRNPK | P61978 | Heterogeneous nuclear ribonucleoprotein K | chr9 | Not Cancer Driver | No | 1 | hippie | 75 | 302 | 59 | 59 | 0 |
HNRNPM | HNRNPM | P52272 | Heterogeneous nuclear ribonucleoprotein M | chr19 | Not Cancer Driver | No | 1 | hippie | 108 | 463 | 67 | 67 | 0 |
HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | Not Cancer Driver | No | 1 | hippie | 77 | 504 | 45 | 45 | 0 |
HSCB | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 25 | 6 | 6 | 0 |
HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | Census, Compendium | Yes | 1 | hippie | 106 | 257 | 37 | 37 | 0 |
HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | Census, Compendium | Yes | 1 | hippie | 100 | 254 | 43 | 43 | 0 |
HSP90B1 | HSP90B1 | P14625 | Endoplasmin | chr12 | Not Cancer Driver | No | 1 | hippie | 94 | 268 | 35 | 35 | 0 |
HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | Not Cancer Driver | No | 1 | hippie | 24 | 200 | 13 | 13 | 0 |
HSPA2_ENST00000247207 | HSPA2 | P54652 | Heat shock-related 70 kDa protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie | 93 | 286 | 38 | 38 | 0 |
HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | Not Cancer Driver | No | 1 | hippie | 73 | 282 | 35 | 35 | 0 |
HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie | 149 | 251 | 52 | 52 | 0 |
HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 10 | 118 | 8 | 8 | 20 |
HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 61 | 82 | 6 | 6 | 2 |
HSPH1_ENST00000320027 | HSPH1 | Q92598 | Heat shock protein 105 kDa | chr13 | Not Cancer Driver | No | 1 | hippie | 103 | 323 | 42 | 42 | 0 |
HUWE1_ENST00000262854 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | Not Cancer Driver | No | 1 | hippie | 669 | 2091 | 329 | 329 | 21 |
ISYNA1 | ISYNA1 | Q9NPH2 | Inositol-3-phosphate synthase 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 40 | 83 | 2 | 2 | 0 |
KIF5C | KIF5C | O60282 | Kinesin heavy chain isoform 5C | chr2 | Not Cancer Driver | No | 1 | hippie | 155 | 578 | 93 | 93 | 2 |
KLC2_ENST00000394067 | KLC2 | Q9H0B6 | Kinesin light chain 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 75 | 344 | 49 | 49 | 0 |
KPNB1 | KPNB1 | Q14974 | Importin subunit beta-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 92 | 94 | 11 | 11 | 0 |
KRT17 | KRT17 | Q04695 | Keratin, type I cytoskeletal 17 | chr17 | Not Cancer Driver | No | 1 | hippie | 86 | 160 | 31 | 31 | 18 |
KRT71 | KRT71 | Q3SY84 | Keratin, type II cytoskeletal 71 | chr12 | Not Cancer Driver | No | 1 | hippie | 105 | 103 | 25 | 25 | 1 |
LANCL1_ENST00000450366 | LANCL1 | O43813 | Glutathione S-transferase LANCL1 | chr2 | Not Cancer Driver | No | 1 | hippie | 45 | 10 | 0 | 0 | 0 |
LDHA_ENST00000422447 | LDHA | P00338 | L-lactate dehydrogenase A chain | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 9 | 0 | 0 | 0 |
LDHB_ENST00000350669 | LDHB | P07195 | L-lactate dehydrogenase B chain | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 15 | 2 | 2 | 11 |
LGALS3BP | LGALS3BP | Q08380 | Galectin-3-binding protein | chr17 | Not Cancer Driver | No | 1 | hippie | 62 | 9 | 0 | 0 | 0 |
LRPPRC | LRPPRC | P42704 | Leucine-rich PPR motif-containing protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 131 | 18 | 2 | 2 | 1 |
MAP1B | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | Not Cancer Driver | No | 1 | hippie | 332 | 1947 | 278 | 278 | 0 |
MAPK6 | MAPK6 | Q16659 | Mitogen-activated protein kinase 6 | chr15 | Not Cancer Driver | No | 1 | hippie | 79 | 165 | 20 | 20 | 0 |
MDH2 | MDH2 | P40926 | Malate dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie | 39 | 8 | 1 | 1 | 3 |
MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
MICB | MICB | Q29980 | MHC class I polypeptide-related sequence B | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 175 | 22 | 22 | 0 |
MKRN2 | MKRN2 | Q9H000 | E3 ubiquitin-protein ligase makorin-2 | chr3 | Not Cancer Driver | No | 1 | hippie | 45 | 145 | 16 | 16 | 0 |
MTCH2 | MTCH2 | Q9Y6C9 | Mitochondrial carrier homolog 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 45 | 11 | 0 | 0 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
MYL6_ENST00000548293 | MYL6 | P60660 | Myosin light polypeptide 6 | chr12 | Not Cancer Driver | No | 1 | hippie | 13 | 17 | 1 | 1 | 0 |
NAP1L1 | NAP1L1 | P55209 | Nucleosome assembly protein 1-like 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 47 | 207 | 31 | 31 | 0 |
NDUFS2 | NDUFS2 | O75306 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 58 | 49 | 5 | 5 | 4 |
NDUFS3 | NDUFS3 | O75489 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 34 | 26 | 3 | 3 | 2 |
NIPBL | NIPBL | Q6KC79 | Nipped-B-like protein | chr5 | Compendium | Yes | 1 | hippie, biogrid | 353 | 1528 | 184 | 184 | 37 |
NIT2 | NIT2 | Q9NQR4 | Omega-amidase NIT2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 0 | 0 | 0 | 0 |
NME1_ENST00000393196 | NME1 | P15531 | Nucleoside diphosphate kinase A | chr17 | Not Cancer Driver | No | 1 | hippie | 11 | 10 | 0 | 0 | 0 |
NME2 | NME2 | P22392 | Nucleoside diphosphate kinase B | chr17 | Not Cancer Driver | No | 1 | hippie | 13 | 11 | 1 | 1 | 0 |
NR3C1_ENST00000343796 | NR3C1 | P04150 | Glucocorticoid receptor | chr5 | Not Cancer Driver | No | 1 | hippie | 92 | 362 | 37 | 37 | 12 |
OGDH | OGDH | Q02218 | 2-oxoglutarate dehydrogenase complex component E1 | chr7 | Not Cancer Driver | No | 1 | hippie | 150 | 106 | 19 | 19 | 0 |
P4HB | P4HB | P07237 | Protein disulfide-isomerase | chr17 | Not Cancer Driver | No | 1 | hippie | 61 | 79 | 15 | 15 | 1 |
PABPC1 | PABPC1 | P11940 | Polyadenylate-binding protein 1 | chr8 | Census, Compendium | Yes | 1 | hippie | 100 | 317 | 55 | 55 | 0 |
PABPC4_ENST00000372857 | PABPC4 | Q13310 | Polyadenylate-binding protein 4 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 89 | 253 | 49 | 49 | 0 |
PACS1 | PACS1 | Q6VY07 | Phosphofurin acidic cluster sorting protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 121 | 511 | 65 | 65 | 1 |
PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 119 | 320 | 34 | 34 | 0 |
PCBP1 | PCBP1 | Q15365 | Poly(rC)-binding protein 1 | chr2 | Census, Compendium | Yes | 1 | hippie | 65 | 166 | 24 | 24 | 0 |
PCBP2_ENST00000439930 | PCBP2 | Q15366 | Poly(rC)-binding protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 40 | 200 | 24 | 24 | 0 |
PCMT1_ENST00000464889 | PCMT1 | A0A0A0MRJ6 | Protein-L-isoaspartate O-methyltransferase | chr6 | Not Cancer Driver | No | 1 | hippie | 34 | 38 | 4 | 4 | 0 |
PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie | 70 | 43 | 6 | 6 | 20 |
PDHB | PDHB | P11177 | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 32 | 4 | 0 | 0 | 2 |
PDIA3 | PDIA3 | P30101 | Protein disulfide-isomerase A3 | chr15 | Not Cancer Driver | No | 1 | hippie | 57 | 98 | 11 | 11 | 0 |
PGK1 | PGK1 | P00558 | Phosphoglycerate kinase 1 | chrX | Not Cancer Driver | No | 1 | hippie | 61 | 40 | 5 | 5 | 9 |
PIAS1_ENST00000249636 | PIAS1 | O75925 | E3 SUMO-protein ligase PIAS1 | chr15 | Not Cancer Driver | No | 1 | hippie | 80 | 241 | 43 | 43 | 0 |
PLB1 | PLB1 | Q6P1J6 | Phospholipase B1, membrane-associated | chr2 | Not Cancer Driver | No | 1 | intact | 223 | 399 | 57 | 57 | 0 |
PLBD2 | PLBD2 | Q8NHP8 | Putative phospholipase B-like 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 29 | 6 | 6 | 0 |
PLD3_ENST00000409735 | PLD3 | Q8IV08 | 5'-3' exonuclease PLD3 | chr19 | Not Cancer Driver | No | 1 | biogrid | 70 | 62 | 7 | 7 | 0 |
PLEC | PLEC | Q15149 | Plectin | chr8 | Not Cancer Driver | No | 1 | hippie | 677 | 2130 | 272 | 272 | 2 |
PPIA | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | Not Cancer Driver | No | 1 | hippie | 11 | 24 | 3 | 3 | 0 |
PPP1CA_ENST00000376745 | PPP1CA | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | chr11 | Not Cancer Driver | No | 1 | hippie | 38 | 27 | 6 | 6 | 0 |
PPP2R1A | PPP2R1A | P30153 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | chr19 | Census, Compendium | Yes | 1 | hippie | 179 | 0 | 0 | 0 | 4 |
PPP3CC_ENST00000240139 | PPP3CC | P48454 | Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform | chr8 | Not Cancer Driver | No | 1 | hippie | 47 | 91 | 7 | 7 | 0 |
PRDX1_ENST00000319248 | PRDX1 | Q06830 | Peroxiredoxin-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 22 | 40 | 5 | 5 | 0 |
PRDX2 | PRDX2 | P32119 | Peroxiredoxin-2 | chr19 | Not Cancer Driver | No | 1 | hippie | 24 | 30 | 4 | 4 | 0 |
PRDX4 | PRDX4 | Q13162 | Peroxiredoxin-4 | chrX | Not Cancer Driver | No | 1 | hippie | 36 | 29 | 2 | 2 | 0 |
PRDX5 | PRDX5 | P30044 | Peroxiredoxin-5, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 0 | 0 | 0 | 0 |
PRRC2C | PRRC2C | Q9Y520-4 | Isoform 4 of Protein PRRC2C | chr1 | Not Cancer Driver | No | 1 | hippie | 296 | 2713 | 287 | 287 | 0 |
PSMA6 | PSMA6 | P60900 | Proteasome subunit alpha type-6 | chr14 | Not Cancer Driver | No | 1 | hippie | 37 | 2 | 1 | 1 | 0 |
RBBP4 | RBBP4 | Q09028 | Histone-binding protein RBBP4 | chr1 | Not Cancer Driver | No | 1 | hippie | 53 | 169 | 23 | 23 | 0 |
RBM14-RBM4 | RBM14-RBM4 | Q96PK6-5 | Isoform 5 of RNA-binding protein 14 | chr11 | Not Cancer Driver | No | 1 | biogrid | 41 | 93 | 8 | 8 | 0 |
RBP1_ENST00000619087 | RBP1 | P09455 | Retinol-binding protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 0 |
RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 287 | 1355 | 164 | 164 | 0 |
RPA2_ENST00000373912 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | Not Cancer Driver | No | 1 | hippie | 28 | 114 | 16 | 16 | 0 |
RPL10A | RPL10A | P62906 | 60S ribosomal protein L10a | chr6 | Not Cancer Driver | No | 1 | hippie | 22 | 16 | 0 | 0 | 0 |
RPL12 | RPL12 | P30050 | 60S ribosomal protein L12 | chr9 | Not Cancer Driver | No | 1 | hippie | 13 | 75 | 6 | 6 | 0 |
RPL22 | RPL22 | P35268 | 60S ribosomal protein L22 | chr1 | Census, Compendium | Yes | 1 | hippie | 26 | 15 | 1 | 1 | 0 |
RPL23A | RPL23A | P62750 | 60S ribosomal protein L23a | chr17 | Not Cancer Driver | No | 1 | hippie | 21 | 70 | 13 | 13 | 0 |
RPL6 | RPL6 | Q02878 | 60S ribosomal protein L6 | chr12 | Not Cancer Driver | No | 1 | hippie | 41 | 159 | 24 | 24 | 0 |
RPL7 | RPL7 | P18124 | 60S ribosomal protein L7 | chr8 | Not Cancer Driver | No | 1 | hippie | 24 | 40 | 4 | 4 | 0 |
RPL7A | RPL7A | P62424 | 60S ribosomal protein L7a | chr9 | Not Cancer Driver | No | 1 | hippie | 27 | 100 | 5 | 5 | 0 |
RPL9 | RPL9 | Q53Z07 | 60S ribosomal protein L9 | chr4 | Not Cancer Driver | No | 1 | hippie | 30 | 3 | 0 | 0 | 0 |
RPLP0_ENST00000228306 | RPLP0 | P05388 | 60S acidic ribosomal protein P0 | chr12 | Not Cancer Driver | No | 1 | hippie | 44 | 36 | 4 | 4 | 0 |
RPLP2_ENST00000530797 | RPLP2 | P05387 | 60S acidic ribosomal protein P2 | chr11 | Not Cancer Driver | No | 1 | hippie | 12 | 59 | 5 | 5 | 0 |
RPN1 | RPN1 | P04843 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | chr3 | Census | Yes | 1 | hippie | 50 | 69 | 3 | 3 | 0 |
RPS12 | RPS12 | P25398 | 40S ribosomal protein S12 | chr6 | Not Cancer Driver | No | 1 | hippie | 17 | 0 | 0 | 0 | 0 |
RPS13 | RPS13 | P62277 | 40S ribosomal protein S13 | chr11 | Not Cancer Driver | No | 1 | hippie | 19 | 18 | 5 | 5 | 0 |
RPS19_ENST00000600467 | RPS19 | P39019 | 40S ribosomal protein S19 | chr19 | Not Cancer Driver | No | 1 | hippie | 15 | 61 | 3 | 3 | 23 |
RPS2 | RPS2 | P15880 | 40S ribosomal protein S2 | chr16 | Not Cancer Driver | No | 1 | hippie | 34 | 85 | 14 | 14 | 0 |
RPS20_ENST00000521262 | RPS20 | P60866 | 40S ribosomal protein S20 | chr8 | Not Cancer Driver | No | 1 | hippie | 18 | 53 | 8 | 8 | 0 |
RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 48 | 4 | 4 | 0 |
RTCB | RTCB | Q9Y3I0 | RNA-splicing ligase RtcB homolog | chr22 | Not Cancer Driver | No | 1 | hippie | 57 | 74 | 7 | 7 | 0 |
RTL1 | RTL1 | A6NKG5 | Retrotransposon-like protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 197 | 354 | 85 | 85 | 0 |
RTRAF | RTRAF | Q9Y224 | RNA transcription, translation and transport factor protein | chr14 | Not Cancer Driver | No | 1 | hippie | 24 | 35 | 1 | 1 | 0 |
RUVBL1 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 54 | 67 | 7 | 7 | 0 |
SARM1 | SARM1 | Q6SZW1 | NAD(+) hydrolase SARM1 | chr17 | Not Cancer Driver | No | 1 | hippie | 36 | 80 | 4 | 4 | 0 |
SCG2 | SCG2 | P13521 | Secretogranin-2 | chr2 | Not Cancer Driver | No | 1 | hippie | 116 | 531 | 103 | 103 | 0 |
SGSH | SGSH | P51688 | N-sulphoglucosamine sulphohydrolase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 44 | 2 | 2 | 56 |
SLC25A1 | SLC25A1 | P53007 | Tricarboxylate transport protein, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie | 22 | 34 | 2 | 2 | 17 |
SLC25A13_ENST00000265631 | SLC25A13 | Q9UJS0 | Calcium-binding mitochondrial carrier protein Aralar2 | chr7 | Not Cancer Driver | No | 1 | hippie | 111 | 23 | 2 | 2 | 1 |
SLC25A4 | SLC25A4 | P12235 | ADP/ATP translocase 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 9 |
SLC25A5 | SLC25A5 | P05141 | ADP/ATP translocase 2 | chrX | Not Cancer Driver | No | 1 | hippie | 41 | 0 | 0 | 0 | 0 |
SLC25A6 | SLC25A6 | P12236 | ADP/ATP translocase 3 | chrX | Not Cancer Driver | No | 1 | hippie | 41 | 0 | 0 | 0 | 0 |
SLC9A3R2 | SLC9A3R2 | Q15599 | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 328 | 26 | 26 | 0 |
SNRPD3 | SNRPD3 | P62318 | Small nuclear ribonucleoprotein Sm D3 | chr22 | Not Cancer Driver | No | 1 | hippie | 20 | 43 | 13 | 13 | 0 |
SPAG8_ENST00000396638 | SPAG8 | Q99932 | Sperm-associated antigen 8 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 46 | 399 | 36 | 36 | 0 |
SPRTN | SPRTN | Q9H040 | DNA-dependent metalloprotease SPRTN | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 252 | 38 | 38 | 1 |
SPTAN1_ENST00000372731 | SPTAN1 | Q13813 | Spectrin alpha chain, non-erythrocytic 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 315 | 980 | 114 | 114 | 0 |
SPTBN1 | SPTBN1 | Q01082 | Spectrin beta chain, non-erythrocytic 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 311 | 869 | 123 | 123 | 0 |
SSB | SSB | P05455 | Lupus La protein | chr2 | Not Cancer Driver | No | 1 | hippie | 39 | 181 | 18 | 18 | 0 |
STIL_ENST00000360380 | STIL | Q15468 | SCL-interrupting locus protein | chr1 | Census, Compendium | Yes | 1 | hippie | 147 | 735 | 85 | 85 | 1 |
STIP1_ENST00000305218 | STIP1 | P31948 | Stress-induced-phosphoprotein 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 74 | 270 | 39 | 39 | 0 |
STRAP | STRAP | Q9Y3F4 | Serine-threonine kinase receptor-associated protein | chr12 | Not Cancer Driver | No | 1 | hippie | 44 | 40 | 5 | 5 | 0 |
TANK | TANK | Q92844 | TRAF family member-associated NF-kappa-B activator | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 42 | 302 | 26 | 26 | 0 |
TCOF1 | TCOF1 | Q13428 | Treacle protein | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 142 | 1454 | 141 | 141 | 1 |
TCP1 | TCP1 | P17987 | T-complex protein 1 subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie | 54 | 55 | 10 | 10 | 0 |
TFG | TFG | Q92734 | Protein TFG | chr3 | Census, Compendium | Yes | 1 | hippie | 45 | 290 | 34 | 34 | 3 |
TIMM13 | TIMM13 | Q9Y5L4 | Mitochondrial import inner membrane translocase subunit Tim13 | chr19 | Not Cancer Driver | No | 1 | hippie | 7 | 20 | 1 | 1 | 0 |
TMEM192 | TMEM192 | Q8IY95 | Transmembrane protein 192 | chr4 | Not Cancer Driver | No | 1 | hippie | 31 | 5 | 1 | 1 | 0 |
TMEM9_ENST00000485839 | TMEM9 | Q9P0T7 | Proton-transporting V-type ATPase complex assembly regulator TMEM9 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 23 | 3 | 3 | 0 |
TPI1_ENST00000396705 | TPI1 | P60174 | Triosephosphate isomerase | chr12 | Not Cancer Driver | No | 1 | hippie | 40 | 15 | 2 | 2 | 7 |
TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
TUBB2A | TUBB2A | Q13885 | Tubulin beta-2A chain | chr6 | Not Cancer Driver | No | 1 | hippie | 44 | 70 | 13 | 13 | 2 |
TUBB3 | TUBB3 | Q13509 | Tubulin beta-3 chain | chr16 | Not Cancer Driver | No | 1 | hippie | 67 | 53 | 10 | 10 | 12 |
UBAP2L | UBAP2L | Q14157 | Ubiquitin-associated protein 2-like | chr1 | Not Cancer Driver | No | 1 | hippie | 129 | 1039 | 128 | 128 | 0 |
UBE2N | UBE2N | P61088 | Ubiquitin-conjugating enzyme E2 N | chr12 | Not Cancer Driver | No | 1 | hippie | 25 | 24 | 3 | 3 | 0 |
UGGT1 | UGGT1 | Q9NYU2 | UDP-glucose:glycoprotein glucosyltransferase 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 169 | 161 | 20 | 20 | 0 |
VAPB | VAPB | O95292 | Vesicle-associated membrane protein-associated protein B/C | chr20 | Not Cancer Driver | No | 1 | hippie | 16 | 138 | 8 | 8 | 3 |
VCAM1 | VCAM1 | P19320 | Vascular cell adhesion protein 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 188 | 110 | 28 | 28 | 0 |
VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 186 | 16 | 16 | 16 |
VDAC1_ENST00000395047 | VDAC1 | P21796 | Voltage-dependent anion-selective channel protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 38 | 36 | 4 | 4 | 0 |
VDAC2_ENST00000543351 | VDAC2 | P45880 | Voltage-dependent anion-selective channel protein 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 35 | 9 | 1 | 1 | 0 |
VGF | VGF | O15240 | Neurosecretory protein VGF | chr7 | Not Cancer Driver | No | 1 | hippie | 48 | 593 | 47 | 47 | 0 |
VIM_ENST00000224237 | VIM | P08670 | Vimentin | chr10 | Not Cancer Driver | No | 1 | hippie | 84 | 316 | 57 | 57 | 1 |
WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 0 | 0 | 0 | 2 |
XRCC1 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 426 | 53 | 53 | 1 |
YWHAB_ENST00000353703 | YWHAB | P31946 | 14-3-3 protein beta/alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 22 | 109 | 4 | 4 | 0 |
YWHAE | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | Census | Yes | 1 | hippie | 32 | 41 | 3 | 3 | 0 |
YWHAG | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | Not Cancer Driver | No | 1 | hippie | 26 | 77 | 9 | 9 | 2 |
YWHAQ | YWHAQ | P27348 | 14-3-3 protein theta | chr2 | Not Cancer Driver | No | 1 | hippie | 29 | 41 | 6 | 6 | 0 |
YWHAZ_ENST00000395956 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | hippie | 30 | 81 | 10 | 10 | 0 |
ZFYVE26 | ZFYVE26 | Q68DK2 | Zinc finger FYVE domain-containing protein 26 | chr14 | Not Cancer Driver | No | 1 | hippie | 307 | 561 | 71 | 71 | 0 |
ZNF829_ENST00000391711 | ZNF829 | Q3KNS6 | Zinc finger protein 829 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 83 | 57 | 19 | 19 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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