Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| APC | APC | P25054 | Adenomatous polyposis coli protein | chr5 | Census, Compendium | Yes | 1 | hippie | 412 | 2406 | 345 | 345 | 22 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
| ARHGEF2 | ARHGEF2 | Q92974 | Rho guanine nucleotide exchange factor 2 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 146 | 450 | 70 | 70 | 0 |
| AXIN1 | AXIN1 | O15169 | Axin-1 | chr16 | Census, Compendium | Yes | 2 | hippie, biogrid | 120 | 619 | 88 | 88 | 4 |
| AXIN2 | AXIN2 | Q9Y2T1 | Axin-2 | chr17 | Census, Compendium | Yes | 1 | hippie | 114 | 547 | 77 | 77 | 0 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | Census, Compendium | Yes | 1 | hippie | 24 | 72 | 5 | 5 | 0 |
| BEST1_ENST00000378043 | BEST1 | O76090 | Bestrophin-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 47 | 229 | 18 | 18 | 108 |
| BRD1_ENST00000216267 | BRD1 | O95696 | Bromodomain-containing protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 171 | 425 | 68 | 68 | 0 |
| BUB1B | BUB1B | O60566 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta | chr15 | Census | Yes | 1 | hippie | 96 | 480 | 35 | 35 | 7 |
| C1orf21 | C1orf21 | Q9H246 | Uncharacterized protein C1orf21 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 16 | 121 | 16 | 16 | 0 |
| CBX5 | CBX5 | P45973 | Chromobox protein homolog 5 | chr12 | Not Cancer Driver | No | 1 | hippie | 21 | 116 | 12 | 12 | 0 |
| CDC20 | CDC20 | Q12834 | Cell division cycle protein 20 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 44 | 198 | 15 | 15 | 0 |
| CDC27_ENST00000066544 | CDC27 | P30260 | Cell division cycle protein 27 homolog | chr17 | Not Cancer Driver | No | 1 | hippie | 179 | 289 | 75 | 75 | 0 |
| CDK17 | CDK17 | Q00537 | Cyclin-dependent kinase 17 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 198 | 26 | 26 | 0 |
| CHEK2_ENST00000405598 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | Census, Compendium | Yes | 1 | hippie | 335 | 157 | 130 | 130 | 13 |
| CRYBG1 | CRYBG1 | Q9Y4K1 | Beta/gamma crystallin domain-containing protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 211 | 1006 | 124 | 124 | 0 |
| CSNK1A1_ENST00000377843 | CSNK1A1 | P48729 | Casein kinase I isoform alpha | chr5 | Not Cancer Driver | No | 1 | hippie | 44 | 46 | 3 | 3 | 0 |
| CTLA4 | CTLA4 | P16410 | Cytotoxic T-lymphocyte protein 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 37 | 3 | 0 | 0 | 1 |
| DAPK1_ENST00000622514 | DAPK1 | P53355 | Death-associated protein kinase 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 193 | 114 | 11 | 11 | 0 |
| DZIP1_ENST00000376829 | DZIP1 | Q86YF9 | Cilium assembly protein DZIP1 | chr13 | Not Cancer Driver | No | 1 | hippie | 143 | 523 | 92 | 92 | 2 |
| EIF2AK2_ENST00000395127 | EIF2AK2 | P19525 | Interferon-induced, double-stranded RNA-activated protein kinase | chr2 | Not Cancer Driver | No | 1 | hippie | 59 | 188 | 22 | 22 | 0 |
| EPHA1 | EPHA1 | P21709 | Ephrin type-A receptor 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 147 | 211 | 38 | 38 | 0 |
| ERGIC2 | ERGIC2 | Q96RQ1 | Endoplasmic reticulum-Golgi intermediate compartment protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 25 | 2 | 2 | 0 |
| ERGIC3_ENST00000348547 | ERGIC3 | Q9Y282 | Endoplasmic reticulum-Golgi intermediate compartment protein 3 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 23 | 3 | 3 | 0 |
| ERICH4 | ERICH4 | A6NGS2 | Glutamate-rich protein 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 1 | 92 | 1 | 1 | 0 |
| ESPL1 | ESPL1 | Q14674 | Separin | chr12 | Not Cancer Driver | No | 1 | hippie | 211 | 380 | 39 | 39 | 0 |
| FAAP20_ENST00000378546 | FAAP20 | Q6NZ36 | Fanconi anemia core complex-associated protein 20 | chr1 | Not Cancer Driver | No | 1 | hippie | 23 | 137 | 19 | 19 | 0 |
| FAM13A | FAM13A | O94988 | Protein FAM13A | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 139 | 630 | 81 | 81 | 0 |
| FAM43A | FAM43A | Q8N2R8 | Protein FAM43A | chr3 | Not Cancer Driver | No | 3 | hippie, biogrid | 29 | 222 | 14 | 14 | 0 |
| FMR1 | FMR1 | Q06787 | Synaptic functional regulator FMR1 | chrX | Not Cancer Driver | No | 1 | hippie | 124 | 327 | 70 | 70 | 3 |
| GNL3 | GNL3 | Q9BVP2 | Guanine nucleotide-binding protein-like 3 | chr3 | Not Cancer Driver | No | 1 | hippie | 56 | 257 | 21 | 21 | 0 |
| ITGB7 | ITGB7 | P26010 | Integrin beta-7 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 125 | 3 | 3 | 0 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | Census, Compendium | Yes | 1 | hippie | 136 | 59 | 5 | 5 | 5 |
| KLHL14 | KLHL14 | Q9P2G3 | Kelch-like protein 14 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 117 | 81 | 10 | 10 | 0 |
| KNDC1 | KNDC1 | Q76NI1 | Kinase non-catalytic C-lobe domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 276 | 805 | 124 | 124 | 0 |
| KSR1_ENST00000644974 | KSR1 | Q8IVT5 | Kinase suppressor of Ras 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 114 | 404 | 58 | 58 | 0 |
| MAP3K3_ENST00000361733 | MAP3K3 | Q99759 | Mitogen-activated protein kinase kinase kinase 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 74 | 355 | 44 | 44 | 0 |
| MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | Not Cancer Driver | No | 1 | hippie | 128 | 750 | 126 | 126 | 18 |
| MOS | MOS | P00540 | Proto-oncogene serine/threonine-protein kinase mos | chr8 | Not Cancer Driver | No | 3 | hippie, biogrid | 94 | 16 | 4 | 4 | 0 |
| MTCL1_ENST00000306329 | MTCL1 | Q9Y4B5 | Microtubule cross-linking factor 1 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 267 | 1681 | 232 | 232 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
| NEK1_ENST00000439128 | NEK1 | Q96PY6 | Serine/threonine-protein kinase Nek1 | chr4 | Not Cancer Driver | No | 1 | hippie | 131 | 879 | 98 | 98 | 3 |
| NHSL1 | NHSL1 | Q5SYE7 | NHS-like protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 1535 | 58 | 58 | 0 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | Not Cancer Driver | No | 1 | hippie | 168 | 347 | 38 | 38 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PLEKHA5_ENST00000299275 | PLEKHA5 | Q9HAU0 | Pleckstrin homology domain-containing family A member 5 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 144 | 869 | 114 | 114 | 0 |
| PPFIA1 | PPFIA1 | Q13136 | Liprin-alpha-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 164 | 865 | 126 | 126 | 0 |
| PPME1_ENST00000328257 | PPME1 | Q9Y570 | Protein phosphatase methylesterase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 146 | 9 | 9 | 0 |
| PPP2CA | PPP2CA | P67775 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | chr5 | Not Cancer Driver | No | 3 | hippie, biogrid | 41 | 12 | 1 | 1 | 8 |
| PPP2CB | PPP2CB | P62714 | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | chr8 | Not Cancer Driver | No | 3 | hippie, biogrid | 37 | 12 | 0 | 0 | 0 |
| PPP2R1A | PPP2R1A | P30153 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | chr19 | Census, Compendium | Yes | 3 | hippie, biogrid | 179 | 0 | 0 | 0 | 4 |
| PPP2R1B_ENST00000527614 | PPP2R1B | P30154 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 72 | 17 | 1 | 1 | 0 |
| PPP2R2D | PPP2R2D | Q66LE6 | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform | chr10 | Not Cancer Driver | No | 1 | hippie | 50 | 65 | 9 | 9 | 0 |
| PPP2R5C_ENST00000334743 | PPP2R5C | Q13362 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | chr14 | Not Cancer Driver | No | 1 | hippie | 65 | 89 | 16 | 16 | 0 |
| PPP2R5D | PPP2R5D | Q14738 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 64 | 178 | 13 | 13 | 4 |
| PPP2R5E | PPP2R5E | Q16537 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 86 | 20 | 20 | 0 |
| PRR14_ENST00000300835 | PRR14 | Q9BWN1 | Proline-rich protein 14 | chr16 | Compendium | Yes | 2 | hippie, biogrid | 81 | 571 | 78 | 78 | 0 |
| PTTG1_ENST00000520452 | PTTG1 | O95997 | Securin | chr5 | Not Cancer Driver | No | 1 | hippie | 17 | 141 | 6 | 6 | 0 |
| PYGM | PYGM | P11217 | Glycogen phosphorylase, muscle form | chr11 | Not Cancer Driver | No | 1 | hippie | 153 | 39 | 4 | 4 | 17 |
| RANGAP1_ENST00000356244 | RANGAP1 | P46060 | Ran GTPase-activating protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 65 | 159 | 17 | 17 | 0 |
| RNF41_ENST00000615206 | RNF41 | Q9H4P4 | E3 ubiquitin-protein ligase NRDP1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 33 | 2 | 2 | 0 |
| SET | SET | Q01105 | Protein SET | chr9 | Census, Compendium | Yes | 1 | hippie | 35 | 221 | 26 | 26 | 2 |
| SGO1 | SGO1 | Q5FBB7 | Shugoshin 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 57 | 360 | 39 | 39 | 1 |
| SGO2 | SGO2 | Q562F6 | Shugoshin 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 164 | 1025 | 134 | 134 | 0 |
| SHC1_ENST00000368445 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 84 | 397 | 58 | 58 | 0 |
| SLFN11_ENST00000308377 | SLFN11 | Q7Z7L1 | Schlafen family member 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 177 | 34 | 8 | 8 | 0 |
| SOGA1 | SOGA1 | O94964-2 | Isoform 2 of Protein SOGA1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 188 | 1118 | 100 | 100 | 0 |
| SOGA3 | SOGA3 | Q5TF21 | Protein SOGA3 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 180 | 792 | 137 | 137 | 0 |
| SP110_ENST00000358662 | SP110 | Q9HB58 | Sp110 nuclear body protein | chr2 | Not Cancer Driver | No | 1 | hippie | 92 | 368 | 54 | 54 | 0 |
| SPRED1 | SPRED1 | Q7Z699 | Sprouty-related, EVH1 domain-containing protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 71 | 194 | 35 | 35 | 2 |
| TLX1 | TLX1 | P31314 | T-cell leukemia homeobox protein 1 | chr10 | Census | Yes | 1 | hippie | 28 | 223 | 17 | 17 | 0 |
| TNNT2 | TNNT2 | P45379 | Troponin T, cardiac muscle | chr1 | Not Cancer Driver | No | 1 | hippie | 59 | 272 | 53 | 53 | 21 |
| TP63 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | Census, Compendium | Yes | 1 | hippie | 229 | 398 | 143 | 143 | 28 |
| TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
| UBE2S | UBE2S | Q16763 | Ubiquitin-conjugating enzyme E2 S | chr19 | Not Cancer Driver | No | 1 | hippie | 25 | 102 | 12 | 12 | 0 |
| USHBP1 | USHBP1 | Q8N6Y0 | Usher syndrome type-1C protein-binding protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 118 | 583 | 95 | 95 | 0 |
| USP15 | USP15 | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 136 | 259 | 39 | 39 | 0 |
| WNT3A | WNT3A | P56704 | Protein Wnt-3a | chr1 | Not Cancer Driver | No | 3 | hippie, biogrid | 77 | 37 | 5 | 5 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|