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PPP2R5A ,PPP2R5A ,Q15172
  • Uniprot Accession= Q15172
  • Ensembl Transcript= ENST00000261461.6
  • Uniprot Name= PPP2R5A
  • Name= Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 28
  • Number of Interaction partner in hippie: 78
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
APC APC P25054 Adenomatous polyposis coli protein chr5 Census, Compendium Yes 1 hippie 412 2406 345 345 22
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 Not Cancer Driver No 2 hippie, biogrid 146 450 70 70 0
AXIN1 AXIN1 O15169 Axin-1 chr16 Census, Compendium Yes 2 hippie, biogrid 120 619 88 88 4
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 Census, Compendium Yes 1 hippie 114 547 77 77 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 Census, Compendium Yes 1 hippie 24 72 5 5 0
BEST1_ENST00000378043 BEST1 O76090 Bestrophin-1 chr11 Not Cancer Driver No 1 hippie 47 229 18 18 108
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 Census Yes 1 hippie 96 480 35 35 7
C1orf21 C1orf21 Q9H246 Uncharacterized protein C1orf21 chr1 Not Cancer Driver No 2 hippie, biogrid 16 121 16 16 0
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 Not Cancer Driver No 1 hippie 21 116 12 12 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 Not Cancer Driver No 1 hippie 44 198 15 15 0
CDC27_ENST00000066544 CDC27 P30260 Cell division cycle protein 27 homolog chr17 Not Cancer Driver No 1 hippie 179 289 75 75 0
CDK17 CDK17 Q00537 Cyclin-dependent kinase 17 chr12 Not Cancer Driver No 1 hippie, biogrid 76 198 26 26 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 1 hippie 335 157 130 130 13
CRYBG1 CRYBG1 Q9Y4K1 Beta/gamma crystallin domain-containing protein 1 chr6 Not Cancer Driver No 1 hippie 211 1006 124 124 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 hippie 44 46 3 3 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 Not Cancer Driver No 1 hippie 37 3 0 0 1
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 Not Cancer Driver No 1 hippie 193 114 11 11 0
DZIP1_ENST00000376829 DZIP1 Q86YF9 Cilium assembly protein DZIP1 chr13 Not Cancer Driver No 1 hippie 143 523 92 92 2
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 Not Cancer Driver No 1 hippie 59 188 22 22 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 1 hippie 147 211 38 38 0
ERGIC2 ERGIC2 Q96RQ1 Endoplasmic reticulum-Golgi intermediate compartment protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 37 25 2 2 0
ERGIC3_ENST00000348547 ERGIC3 Q9Y282 Endoplasmic reticulum-Golgi intermediate compartment protein 3 chr20 Not Cancer Driver No 1 hippie, biogrid 53 23 3 3 0
ERICH4 ERICH4 A6NGS2 Glutamate-rich protein 4 chr19 Not Cancer Driver No 1 hippie 1 92 1 1 0
ESPL1 ESPL1 Q14674 Separin chr12 Not Cancer Driver No 1 hippie 211 380 39 39 0
FAAP20_ENST00000378546 FAAP20 Q6NZ36 Fanconi anemia core complex-associated protein 20 chr1 Not Cancer Driver No 1 hippie 23 137 19 19 0
FAM13A FAM13A O94988 Protein FAM13A chr4 Not Cancer Driver No 1 hippie, biogrid 139 630 81 81 0
FAM43A FAM43A Q8N2R8 Protein FAM43A chr3 Not Cancer Driver No 3 hippie, biogrid 29 222 14 14 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX Not Cancer Driver No 1 hippie 124 327 70 70 3
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 Not Cancer Driver No 1 hippie 56 257 21 21 0
ITGB7 ITGB7 P26010 Integrin beta-7 chr12 Not Cancer Driver No 1 hippie, biogrid 80 125 3 3 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 1 hippie 136 59 5 5 5
KLHL14 KLHL14 Q9P2G3 Kelch-like protein 14 chr18 Not Cancer Driver No 1 hippie, biogrid 117 81 10 10 0
KNDC1 KNDC1 Q76NI1 Kinase non-catalytic C-lobe domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 276 805 124 124 0
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 hippie 114 404 58 58 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 hippie 74 355 44 44 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MOS MOS P00540 Proto-oncogene serine/threonine-protein kinase mos chr8 Not Cancer Driver No 3 hippie, biogrid 94 16 4 4 0
MTCL1_ENST00000306329 MTCL1 Q9Y4B5 Microtubule cross-linking factor 1 chr18 Not Cancer Driver No 1 hippie, biogrid 267 1681 232 232 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NEK1_ENST00000439128 NEK1 Q96PY6 Serine/threonine-protein kinase Nek1 chr4 Not Cancer Driver No 1 hippie 131 879 98 98 3
NHSL1 NHSL1 Q5SYE7 NHS-like protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 60 1535 58 58 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 Not Cancer Driver No 1 hippie 168 347 38 38 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA5_ENST00000299275 PLEKHA5 Q9HAU0 Pleckstrin homology domain-containing family A member 5 chr12 Not Cancer Driver No 1 hippie, biogrid 144 869 114 114 0
PPFIA1 PPFIA1 Q13136 Liprin-alpha-1 chr11 Not Cancer Driver No 1 hippie 164 865 126 126 0
PPME1_ENST00000328257 PPME1 Q9Y570 Protein phosphatase methylesterase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 35 146 9 9 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 3 hippie, biogrid 41 12 1 1 8
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 Not Cancer Driver No 3 hippie, biogrid 37 12 0 0 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 3 hippie, biogrid 179 0 0 0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 Not Cancer Driver No 2 hippie, biogrid 72 17 1 1 0
PPP2R2D PPP2R2D Q66LE6 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform chr10 Not Cancer Driver No 1 hippie 50 65 9 9 0
PPP2R5C_ENST00000334743 PPP2R5C Q13362 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform chr14 Not Cancer Driver No 1 hippie 65 89 16 16 0
PPP2R5D PPP2R5D Q14738 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform chr6 Not Cancer Driver No 2 hippie, biogrid 64 178 13 13 4
PPP2R5E PPP2R5E Q16537 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform chr14 Not Cancer Driver No 1 hippie, biogrid 68 86 20 20 0
PRR14_ENST00000300835 PRR14 Q9BWN1 Proline-rich protein 14 chr16 Compendium Yes 2 hippie, biogrid 81 571 78 78 0
PTTG1_ENST00000520452 PTTG1 O95997 Securin chr5 Not Cancer Driver No 1 hippie 17 141 6 6 0
PYGM PYGM P11217 Glycogen phosphorylase, muscle form chr11 Not Cancer Driver No 1 hippie 153 39 4 4 17
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 Not Cancer Driver No 1 hippie 65 159 17 17 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 Not Cancer Driver No 1 hippie, biogrid 44 33 2 2 0
SET SET Q01105 Protein SET chr9 Census, Compendium Yes 1 hippie 35 221 26 26 2
SGO1 SGO1 Q5FBB7 Shugoshin 1 chr3 Not Cancer Driver No 1 hippie 57 360 39 39 1
SGO2 SGO2 Q562F6 Shugoshin 2 chr2 Not Cancer Driver No 1 hippie 164 1025 134 134 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 84 397 58 58 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 177 34 8 8 0
SOGA1 SOGA1 O94964-2 Isoform 2 of Protein SOGA1 chr20 Not Cancer Driver No 1 hippie, biogrid 188 1118 100 100 0
SOGA3 SOGA3 Q5TF21 Protein SOGA3 chr6 Not Cancer Driver No 1 hippie, biogrid 180 792 137 137 0
SP110_ENST00000358662 SP110 Q9HB58 Sp110 nuclear body protein chr2 Not Cancer Driver No 1 hippie 92 368 54 54 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 hippie 71 194 35 35 2
TLX1 TLX1 P31314 T-cell leukemia homeobox protein 1 chr10 Census Yes 1 hippie 28 223 17 17 0
TNNT2 TNNT2 P45379 Troponin T, cardiac muscle chr1 Not Cancer Driver No 1 hippie 59 272 53 53 21
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 Census, Compendium Yes 1 hippie 229 398 143 143 28
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 Not Cancer Driver No 1 hippie 25 102 12 12 0
USHBP1 USHBP1 Q8N6Y0 Usher syndrome type-1C protein-binding protein 1 chr19 Not Cancer Driver No 1 hippie 118 583 95 95 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 Not Cancer Driver No 1 hippie, biogrid 136 259 39 39 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 Not Cancer Driver No 3 hippie, biogrid 77 37 5 5 0