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PPP1R8 ,PPP1R8 ,Q12972
  • Uniprot Accession= Q12972
  • Ensembl Transcript= ENST00000311772.9
  • Uniprot Name= PPP1R8
  • Name= Nuclear inhibitor of protein phosphatase 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 7
  • Number of Interaction partner in biogrid: 31
  • Number of Interaction partner in hippie: 71
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
APPBP2 APPBP2 Q92624 Amyloid protein-binding protein 2 chr17 Not Cancer Driver No 1 hippie 61 10 0 0 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 hippie 100 618 77 77 0
CNKSR1 CNKSR1 Q969H4 Connector enhancer of kinase suppressor of ras 1 chr1 Not Cancer Driver No 1 hippie 118 405 68 68 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
CRMP1_ENST00000397890 CRMP1 Q14194 Dihydropyrimidinase-related protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 122 96 15 15 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 hippie 71 75 8 8 4
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 Not Cancer Driver No 1 hippie 43 13 1 1 0
CTNNBL1 CTNNBL1 Q8WYA6 Beta-catenin-like protein 1 chr20 Not Cancer Driver No 1 hippie 72 158 24 24 0
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 81 17 2 2 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 Not Cancer Driver No 1 hippie, biogrid 82 91 15 15 0
DNAJB6 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 Not Cancer Driver No 1 hippie, biogrid 33 198 17 17 3
EED_ENST00000263360 EED O75530 Polycomb protein EED chr11 Census Yes 1 hippie 64 79 11 11 6
ERG28 ERG28 Q9UKR5 Ergosterol biosynthetic protein 28 homolog chr14 Not Cancer Driver No 1 hippie 19 3 0 0 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
FAM98B FAM98B Q52LJ0 Protein FAM98B chr15 Not Cancer Driver No 1 hippie, biogrid 34 244 9 9 0
FBXO25 FBXO25 Q8TCJ0 F-box only protein 25 chr8 Not Cancer Driver No 1 hippie 33 20 0 0 0
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 Not Cancer Driver No 1 hippie 54 0 0 0 0
GBP2 GBP2 P32456 Guanylate-binding protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 75 134 15 15 0
GBP7 GBP7 Q8N8V2 Guanylate-binding protein 7 chr1 Not Cancer Driver No 1 hippie 88 93 8 8 0
GTF2E2 GTF2E2 P29084 Transcription initiation factor IIE subunit beta chr8 Not Cancer Driver No 2 intact, hippie, biogrid 34 130 16 16 2
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HDDC3_ENST00000646620 HDDC3 Q8N4P3 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 chr15 Not Cancer Driver No 1 hippie, biogrid 13 76 9 9 0
HMGA1 HMGA1 P17096 High mobility group protein HMG-I/HMG-Y chr6 Census Yes 1 hippie 6 107 6 6 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HOXC5 HOXC5 Q00444 Homeobox protein Hox-C5 chr12 Not Cancer Driver No 1 hippie, biogrid 35 141 20 20 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 2 intact, hippie, biogrid 149 251 52 52 0
INS INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 15 5 1 1 22
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
LSM2 LSM2 Q9Y333 U6 snRNA-associated Sm-like protein LSm2 chr6 Not Cancer Driver No 1 hippie 10 3 0 0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 95 84 12 12 0
MELK MELK Q14680 Maternal embryonic leucine zipper kinase chr9 Not Cancer Driver No 1 hippie 76 162 24 24 0
MRPL42 MRPL42 Q9Y6G3 39S ribosomal protein L42, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 18 52 5 5 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie, biogrid 69 252 26 26 16
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 Not Cancer Driver No 1 hippie 13 11 1 1 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
PPIL1 PPIL1 Q9Y3C6 Peptidyl-prolyl cis-trans isomerase-like 1 chr6 Not Cancer Driver No 1 hippie 25 42 11 11 3
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 7 intact, hippie, biogrid 38 27 6 6 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 2 hippie, biogrid 47 25 5 5 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 7 intact, hippie, biogrid 26 23 4 4 0
PPP1R3A PPP1R3A Q16821 Protein phosphatase 1 regulatory subunit 3A chr7 Not Cancer Driver No 1 hippie 430 807 334 334 1
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 1 hippie 71 109 16 16 0
RAD51D_ENST00000394589 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 Not Cancer Driver No 1 hippie, biogrid 34 49 10 10 0
RBBP4 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 Not Cancer Driver No 1 hippie 53 169 23 23 0
RBM48 RBM48 Q5RL73 RNA-binding protein 48 chr7 Not Cancer Driver No 1 hippie, biogrid 65 176 39 39 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 Not Cancer Driver No 1 hippie, biogrid 63 143 20 20 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RPL35A RPL35A P18077 60S ribosomal protein L35a chr3 Not Cancer Driver No 1 hippie, biogrid 9 25 0 0 1
RTCB RTCB Q9Y3I0 RNA-splicing ligase RtcB homolog chr22 Not Cancer Driver No 1 hippie, biogrid 57 74 7 7 0
RTN4IP1 RTN4IP1 Q8WWV3 Reticulon-4-interacting protein 1, mitochondrial chr6 Not Cancer Driver No 1 hippie 60 15 2 2 1
SETDB1 SETDB1 Q15047 Histone-lysine N-methyltransferase SETDB1 chr1 Census, Compendium Yes 1 hippie, biogrid 184 597 77 77 0
SF3A2 SF3A2 Q15428 Splicing factor 3A subunit 2 chr19 Not Cancer Driver No 1 hippie 30 382 21 21 0
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 Census, Compendium Yes 1 hippie 244 477 80 80 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 84 397 58 58 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 57 58 5 5 1
SNRNP27 SNRNP27 Q8WVK2 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein chr2 Not Cancer Driver No 2 intact, hippie, biogrid 20 155 20 20 0
SNUPN_ENST00000564675 SNUPN O95149 Snurportin-1 chr15 Not Cancer Driver No 1 hippie, biogrid 45 137 17 17 0
STC2 STC2 O76061 Stanniocalcin-2 chr5 Not Cancer Driver No 1 hippie, biogrid 71 112 29 29 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 97 111 23 23 18
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 83 483 46 46 3
TGM1 TGM1 P22735 Protein-glutamine gamma-glutamyltransferase K chr14 Not Cancer Driver No 1 hippie, biogrid 118 230 37 37 65
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 hippie 227 1632 190 190 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 137 425 39 39 0
VPS4B VPS4B O75351 Vacuolar protein sorting-associated protein 4B chr18 Not Cancer Driver No 1 hippie, biogrid 52 195 22 22 0
WASHC3 WASHC3 Q9Y3C0 WASH complex subunit 3 chr12 Not Cancer Driver No 1 hippie 29 100 8 8 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 Not Cancer Driver No 1 hippie 30 41 2 2 0
WIF1 WIF1 Q9Y5W5 Wnt inhibitory factor 1 chr12 Census Yes 1 hippie, biogrid 74 30 3 3 0