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PPP1R15B ,PPP1R15B ,Q5SWA1
  • Number of Interaction partner in intact: 14
  • Number of Interaction partner in biogrid: 54
  • Number of Interaction partner in hippie: 64
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCB5 ABCB5 Q2M3G0 ATP-binding cassette sub-family B member 5 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 370 106 35 35 0
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
ANO4 ANO4 Q32M45 Anoctamin-4 chr12 Not Cancer Driver No 1 hippie, biogrid 320 133 35 35 0
ASB14_ENST00000389601 ASB14 A6NK59 Ankyrin repeat and SOCS box protein 14 chr3 Not Cancer Driver No 1 hippie, biogrid 42 36 0 0 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 80 45 4 4 0
C2CD4B C2CD4B A6NLJ0 C2 calcium-dependent domain-containing protein 4B chr15 Not Cancer Driver No 1 hippie, biogrid 5 191 0 0 0
CHRM4 CHRM4 P08173 Muscarinic acetylcholine receptor M4 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 75 143 27 27 0
CHRM5 CHRM5 P08912 Muscarinic acetylcholine receptor M5 chr15 Not Cancer Driver No 1 hippie, biogrid 74 155 20 20 0
CHRNA9 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 Not Cancer Driver No 3 intact, hippie, biogrid 76 23 6 6 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 Not Cancer Driver No 1 hippie, biogrid 96 338 67 67 1
CYP19A1_ENST00000396404 CYP19A1 P11511 Aromatase chr15 Not Cancer Driver No 1 hippie, biogrid 91 2 1 1 5
DCST1 DCST1 Q5T197 E3 ubiquitin-protein ligase DCST1 chr1 Not Cancer Driver No 1 hippie, biogrid 108 51 9 9 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 28 11 1 1 0
DNAJC1 DNAJC1 Q96KC8 DnaJ homolog subfamily C member 1 chr10 Not Cancer Driver No 1 hippie, biogrid 60 315 44 44 0
DNAJC14_ENST00000317287 DNAJC14 Q6Y2X3 DnaJ homolog subfamily C member 14 chr12 Not Cancer Driver No 1 hippie, biogrid 90 372 53 53 0
DNAJC25 DNAJC25 Q9H1X3 DnaJ homolog subfamily C member 25 chr9 Not Cancer Driver No 1 hippie, biogrid 37 39 3 3 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 Not Cancer Driver No 1 intact 197 121 17 17 0
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 58 176 15 15 0
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 75 20 3 3 7
FGF14_ENST00000376143 FGF14 Q92915 Fibroblast growth factor 14 chr13 Not Cancer Driver No 1 hippie, biogrid 72 93 30 30 1
FGFRL1_ENST00000264748 FGFRL1 Q8N441 Fibroblast growth factor receptor-like 1 chr4 Not Cancer Driver No 1 hippie, biogrid 74 278 34 34 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 71 160 25 25 0
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 Not Cancer Driver No 1 hippie, biogrid 226 28 11 11 16
HPSE2 HPSE2 Q8WWQ2 Inactive heparanase-2 chr10 Not Cancer Driver No 1 hippie, biogrid 123 42 20 20 0
HSD17B11 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 28 3 0 0 0
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 Not Cancer Driver No 1 hippie, biogrid 96 82 16 16 5
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 0
KCNG4 KCNG4 Q8TDN1 Potassium voltage-gated channel subfamily G member 4 chr16 Not Cancer Driver No 1 hippie, biogrid 117 47 10 10 0
LRCH1_ENST00000389798 LRCH1 Q9Y2L9 Leucine-rich repeat and calponin homology domain-containing protein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 95 380 41 41 0
LRP3 LRP3 O75074 Low-density lipoprotein receptor-related protein 3 chr19 Not Cancer Driver No 1 hippie, biogrid 88 214 20 20 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 45 11 0 0 0
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 Not Cancer Driver No 1 hippie 78 47 8 8 0
OR10H1_ENST00000334920 OR10H1 Q9Y4A9 Olfactory receptor 10H1 chr19 Not Cancer Driver No 1 hippie, biogrid 88 0 0 0 0
OTULINL OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 59 21 0 0 0
PCDH10 PCDH10 Q9P2E7 Protocadherin-10 chr4 Not Cancer Driver No 1 hippie, biogrid 395 510 182 182 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 Not Cancer Driver No 1 hippie, biogrid 274 527 114 114 6
PIGH PIGH Q14442 Phosphatidylinositol N-acetylglucosaminyltransferase subunit H chr14 Not Cancer Driver No 1 hippie, biogrid 12 1 0 0 1
PLCD3 PLCD3 Q8N3E9 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 chr17 Not Cancer Driver No 1 hippie, biogrid 61 229 22 22 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 intact, hippie 38 27 6 6 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 intact, hippie 47 25 5 5 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 6 intact, hippie, biogrid 26 23 4 4 0
PTCHD3_ENST00000622555 PTCHD3 Q3KNS1-2 Isoform 2 of Patched domain-containing protein 3 chr10 Not Cancer Driver No 1 hippie, biogrid 133 130 38 38 0
PTGER3_ENST00000370931 PTGER3 P43115 Prostaglandin E2 receptor EP3 subtype chr1 Not Cancer Driver No 3 intact, hippie, biogrid 79 17 2 2 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 27 11 0 0 4
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 1 hippie 115 421 74 74 3
RXFP1_ENST00000307765 RXFP1 Q9HBX9 Relaxin receptor 1 chr4 Not Cancer Driver No 1 hippie, biogrid 152 0 0 0 0
SEC61B SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 11 60 7 7 0
SEC62 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 41 211 23 23 0
SIGLECL1 SIGLECL1 Q8N7X8 SIGLEC family-like protein 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 56 35 14 14 0
SLC17A2_ENST00000265425 SLC17A2 O00624 Sodium-dependent phosphate transport protein 3 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 81 12 5 5 0
SLC27A2 SLC27A2 O14975 Very long-chain acyl-CoA synthetase chr15 Not Cancer Driver No 1 hippie, biogrid 95 4 0 0 0
SULF2_ENST00000484875 SULF2 Q8IWU5 Extracellular sulfatase Sulf-2 chr20 Not Cancer Driver No 1 hippie, biogrid 145 142 18 18 0
TACR3 TACR3 P29371 Neuromedin-K receptor chr4 Not Cancer Driver No 1 hippie, biogrid 137 31 17 17 5
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 Compendium Yes 1 hippie, biogrid 68 102 6 6 5
TMEM9B TMEM9B Q9NQ34 Transmembrane protein 9B chr11 Not Cancer Driver No 1 hippie, biogrid 12 0 0 0 0
TMPRSS3_ENST00000433957 TMPRSS3 P57727 Transmembrane protease serine 3 chr21 Not Cancer Driver No 2 intact, hippie, biogrid 78 8 3 3 8
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 Not Cancer Driver No 1 hippie, biogrid 55 174 17 17 0
TRIM23 TRIM23 P36406 E3 ubiquitin-protein ligase TRIM23 chr5 Not Cancer Driver No 1 intact, hippie 91 39 2 2 0
TULP3_ENST00000448120 TULP3 O75386 Tubby-related protein 3 chr12 Not Cancer Driver No 1 hippie 66 218 29 29 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 Not Cancer Driver No 1 hippie 26 100 7 7 0
UNK UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 79 511 46 46 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VTI1B VTI1B Q9UEU0 Vesicle transport through interaction with t-SNAREs homolog 1B chr14 Not Cancer Driver No 2 hippie, biogrid 25 192 20 20 0
ZDHHC12 ZDHHC12 Q96GR4 Palmitoyltransferase ZDHHC12 chr9 Not Cancer Driver No 1 hippie, biogrid 23 13 1 1 0
ZNRF4 ZNRF4 Q8WWF5 E3 ubiquitin-protein ligase ZNRF4 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 115 99 26 26 0