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PPP1R12B_ENST00000608999 ,PPP1R12B ,O60237
  • Uniprot Accession= O60237
  • Ensembl Transcript= ENST00000608999.5
  • Uniprot Name= PPP1R12B
  • Name= Protein phosphatase 1 regulatory subunit 12B
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 15
  • Number of Interaction partner in biogrid: 32
  • Number of Interaction partner in hippie: 60
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ANK1_ENST00000347528 ANK1 P16157 Ankyrin-1 chr8 Census Yes 1 hippie, biogrid 405 810 171 171 3
ANK2 ANK2 Q01484 Ankyrin-2 chr4 Not Cancer Driver No 1 hippie, biogrid 770 2844 566 566 4
ANK3 ANK3 Q12955 Ankyrin-3 chr10 Not Cancer Driver No 1 hippie, biogrid 860 3054 579 579 0
ANKFY1_ENST00000341657 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 Not Cancer Driver No 1 hippie, biogrid 109 185 29 29 0
ANKHD1 ANKHD1 Q8IWZ3 Ankyrin repeat and KH domain-containing protein 1 chr5 Not Cancer Driver No 1 biogrid 293 1703 193 193 0
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 Q8IWZ3-6 Isoform 6 of Ankyrin repeat and KH domain-containing protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 297 1801 201 201 0
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 Not Cancer Driver No 1 hippie, biogrid 312 1790 221 221 9
ANKRD28 ANKRD28 O15084 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A chr3 Not Cancer Driver No 1 hippie, biogrid 121 115 15 15 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 intact, hippie 144 767 104 104 2
ASB1 ASB1 Q9Y576 Ankyrin repeat and SOCS box protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 49 37 2 2 0
ASB3 ASB3 Q9Y575 Ankyrin repeat and SOCS box protein 3 chr2 Not Cancer Driver No 1 hippie, biogrid 71 0 0 0 0
BBS1 BBS1 Q8NFJ9 Bardet-Biedl syndrome 1 protein chr11 Not Cancer Driver No 1 hippie, biogrid 69 99 14 14 12
CD14 CD14 P08571 Monocyte differentiation antigen CD14 chr5 Not Cancer Driver No 1 intact, hippie 42 60 5 5 0
COPS6 COPS6 Q7L5N1 COP9 signalosome complex subunit 6 chr7 Not Cancer Driver No 1 intact, hippie 38 30 6 6 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
DNPEP_ENST00000273075 DNPEP Q9ULA0 Aspartyl aminopeptidase chr2 Not Cancer Driver No 1 hippie, biogrid 55 90 8 8 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 intact, hippie 505 495 62 62 21
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact, hippie 173 241 26 26 37
FKBP6 FKBP6 O75344 Inactive peptidyl-prolyl cis-trans isomerase FKBP6 chr7 Not Cancer Driver No 3 hippie, biogrid 75 17 1 1 0
GMDS GMDS O60547 GDP-mannose 4,6 dehydratase chr6 Not Cancer Driver No 1 hippie, biogrid 51 53 6 6 0
GRIN2C GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 Not Cancer Driver No 1 intact, hippie 111 276 6 6 0
GSN GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 intact, hippie 76 316 28 28 2
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie, biogrid 37 77 9 9 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
IL16 IL16 Q14005 Pro-interleukin-16 chr15 Not Cancer Driver No 1 hippie 216 959 151 151 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 Not Cancer Driver No 1 hippie, biogrid 49 84 12 12 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 intact, hippie 183 351 35 35 0
ISCU ISCU Q9H1K1 Iron-sulfur cluster assembly enzyme ISCU, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 14 24 3 3 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
LRRC1 LRRC1 Q9BTT6 Leucine-rich repeat-containing protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 76 88 17 17 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 310 1120 160 160 17
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 268 1237 176 176 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie, biogrid 363 686 87 87 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 Census, Compendium Yes 1 hippie, biogrid 282 630 77 77 1
NOTCH3 NOTCH3 Q9UM47 Neurogenic locus notch homolog protein 3 chr19 Not Cancer Driver No 1 hippie, biogrid 306 557 81 81 110
NUAK1 NUAK1 O60285 NUAK family SNF1-like kinase 1 chr12 Not Cancer Driver No 2 hippie, biogrid 142 357 77 77 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 intact, hippie 30 22 3 3 1
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 Not Cancer Driver No 1 hippie 51 149 20 20 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie, biogrid 38 27 6 6 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 6 intact, hippie, biogrid 47 25 5 5 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie, biogrid 26 23 4 4 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 Not Cancer Driver No 1 intact, hippie 107 821 89 89 0
PPP1R13L_ENST00000360957 PPP1R13L Q8WUF5 RelA-associated inhibitor chr19 Not Cancer Driver No 1 hippie, biogrid 117 657 90 90 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 hippie 179 0 0 0 4
PPP6R2_ENST00000216061 PPP6R2 O75170 Serine/threonine-protein phosphatase 6 regulatory subunit 2 chr22 Not Cancer Driver No 1 hippie, biogrid 103 491 63 63 0
PRKG1_ENST00000401604 PRKG1 Q13976 cGMP-dependent protein kinase 1 chr10 Not Cancer Driver No 1 hippie 167 93 22 22 1
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
SIK2 SIK2 Q9H0K1 Serine/threonine-protein kinase SIK2 chr11 Not Cancer Driver No 1 hippie 94 525 56 56 0
SKP1_ENST00000517625 SKP1 P63208 S-phase kinase-associated protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 19 95 17 17 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 103 918 102 102 0
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 Not Cancer Driver No 1 hippie 16 30 5 5 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 Not Cancer Driver No 1 hippie, biogrid 163 480 59 59 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 Not Cancer Driver No 1 hippie, biogrid 117 255 24 24 0
TPP2_ENST00000376065 TPP2 P29144 Tripeptidyl-peptidase 2 chr13 Not Cancer Driver No 1 hippie, biogrid 147 218 40 40 1
TPR TPR P12270 Nucleoprotein TPR chr1 Census Yes 1 hippie 311 1990 266 266 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 Not Cancer Driver No 1 hippie, biogrid 137 425 39 39 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 78 236 25 25 0