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PPOX ,PPOX ,P50336
  • Uniprot Accession= P50336
  • Ensembl Transcript= ENST00000367999.8
  • Uniprot Name= PPOX
  • Name= Protoporphyrinogen oxidase
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 9
  • Number of Interaction partner in biogrid: 52
  • Number of Interaction partner in hippie: 69
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 42 51 2 2 0
ACSM5 ACSM5 Q6NUN0 Acyl-coenzyme A synthetase ACSM5, mitochondrial chr16 Not Cancer Driver No 2 intact, hippie, biogrid 152 84 27 27 0
ADAM7 ADAM7 Q9H2U9 Disintegrin and metalloproteinase domain-containing protein 7 chr8 Not Cancer Driver No 1 hippie, biogrid 241 55 22 22 0
AK4 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 26 24 3 3 0
AMACR_ENST00000335606 AMACR Q9UHK6 Alpha-methylacyl-CoA racemase chr5 Not Cancer Driver No 1 hippie, biogrid 56 38 8 8 3
ANTXR1 ANTXR1 Q9H6X2 Anthrax toxin receptor 1 chr2 Not Cancer Driver No 1 hippie, biogrid 105 183 44 44 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
ARSA ARSA P15289 Arylsulfatase A chr22 Not Cancer Driver No 1 hippie, biogrid 46 61 7 7 97
BPNT1_ENST00000322067 BPNT1 O95861 3'(2'),5'-bisphosphate nucleotidase 1 chr1 Not Cancer Driver No 2 hippie, biogrid 44 9 0 0 0
CA6_ENST00000377443 CA6 P23280 Carbonic anhydrase 6 chr1 Not Cancer Driver No 1 hippie, biogrid 50 56 5 5 0
CBWD1_ENST00000356521 CBWD1 Q9BRT8 COBW domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 27 62 8 8 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 Not Cancer Driver No 1 hippie, biogrid 56 5 2 2 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 43 111 13 13 0
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 15 23 6 6 2
CRYBA4 CRYBA4 P53673 Beta-crystallin A4 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 55 3 3 3 3
DHDH DHDH Q9UQ10 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase chr19 Not Cancer Driver No 1 hippie, biogrid 54 18 2 2 0
DNASE1L1 DNASE1L1 P49184 Deoxyribonuclease-1-like 1 chrX Not Cancer Driver No 1 hippie, biogrid 30 0 0 0 0
ENG ENG P17813 Endoglin chr9 Not Cancer Driver No 1 intact, hippie 60 114 15 15 32
ETFBKMT_ENST00000412352 ETFBKMT Q8IXQ9 Electron transfer flavoprotein beta subunit lysine methyltransferase chr12 Not Cancer Driver No 1 hippie 25 0 0 0 0
FAM83F FAM83F Q8NEG4 Protein FAM83F chr22 Not Cancer Driver No 1 hippie, biogrid 65 255 27 27 0
FCGR3B_ENST00000367964 FCGR3B O75015 Low affinity immunoglobulin gamma Fc region receptor III-B chr1 Not Cancer Driver No 1 hippie, biogrid 58 0 0 0 0
FMOD FMOD Q06828 Fibromodulin chr1 Not Cancer Driver No 1 hippie, biogrid 84 48 10 10 0
GAA_ENST00000390015 GAA P10253 Lysosomal alpha-glucosidase chr17 Not Cancer Driver No 1 hippie, biogrid 101 147 18 18 131
GPR182 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 49 33 4 4 0
GPR45 GPR45 Q9Y5Y3 Probable G-protein coupled receptor 45 chr2 Not Cancer Driver No 1 hippie, biogrid 97 0 0 0 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 97 454 60 60 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie 39 206 19 19 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie 44 127 9 9 2
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 Not Cancer Driver No 1 hippie, biogrid 108 207 38 38 1
IMMP1L IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 20 3 0 0 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie, biogrid 97 400 50 50 0
ISLR ISLR O14498 Immunoglobulin superfamily containing leucine-rich repeat protein chr15 Not Cancer Driver No 1 hippie, biogrid 83 87 13 13 0
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 Not Cancer Driver No 1 hippie, biogrid 37 0 0 0 0
LDHAL6B LDHAL6B Q9BYZ2 L-lactate dehydrogenase A-like 6B chr15 Not Cancer Driver No 1 hippie, biogrid 54 17 2 2 0
LIMK2_ENST00000331728 LIMK2 P53671 LIM domain kinase 2 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 93 146 29 29 0
MAIP1 MAIP1 Q8WWC4 m-AAA protease-interacting protein 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 28 12 0 0 0
MRPS2 MRPS2 Q9Y399 28S ribosomal protein S2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 32 57 6 6 3
MRPS24 MRPS24 Q96EL2 28S ribosomal protein S24, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 20 1 0 0 0
MRPS30 MRPS30 Q9NP92 39S ribosomal protein S30, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 54 53 10 10 0
MTG2 MTG2 Q9H4K7 Mitochondrial ribosome-associated GTPase 2 chr20 Not Cancer Driver No 1 hippie, biogrid 57 47 9 9 0
NAA38_ENST00000575771 NAA38 Q9BRA0 N-alpha-acetyltransferase 38, NatC auxiliary subunit chr17 Not Cancer Driver No 1 hippie, biogrid 11 79 4 4 0
NAAA NAAA Q02083 N-acylethanolamine-hydrolyzing acid amidase chr4 Not Cancer Driver No 1 hippie, biogrid 42 43 3 3 0
NANOG NANOG Q9H9S0 Homeobox protein NANOG chr12 Not Cancer Driver No 1 hippie 46 169 35 35 0
NDUFA10 NDUFA10 O95299 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 48 19 0 0 1
NDUFS7 NDUFS7 O75251 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial chr19 Not Cancer Driver No 2 hippie, biogrid 36 30 3 3 1
NIPSNAP3A NIPSNAP3A Q9UFN0 Protein NipSnap homolog 3A chr9 Not Cancer Driver No 1 hippie, biogrid 26 15 4 4 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
PCDHA12 PCDHA12 Q9UN75 Protocadherin alpha-12 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 327 243 62 62 0
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 Not Cancer Driver No 1 hippie, biogrid 49 18 5 5 0
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 Census Yes 1 hippie 36 186 12 12 0
PPOX PPOX P50336 Protoporphyrinogen oxidase chr1 Not Cancer Driver No 1 hippie 48 34 6 6 56
QRSL1 QRSL1 Q9H0R6 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 63 63 4 4 2
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 intact, hippie 32 65 15 15 0
RAMP2 RAMP2 O60895 Receptor activity-modifying protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 18 34 6 6 0
SCGB2A2 SCGB2A2 Q13296 Mammaglobin-A chr11 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
SDF4 SDF4 Q9BRK5 45 kDa calcium-binding protein chr1 Not Cancer Driver No 1 hippie, biogrid 48 187 30 30 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 Not Cancer Driver No 1 hippie, biogrid 69 17 4 4 1
SNX21 SNX21 Q969T3 Sorting nexin-21 chr20 Not Cancer Driver No 1 hippie, biogrid 29 174 14 14 0
TCTN1_ENST00000551590 TCTN1 Q2MV58 Tectonic-1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 63 47 6 6 0
THBS3 THBS3 P49746 Thrombospondin-3 chr1 Not Cancer Driver No 1 hippie, biogrid 100 283 24 24 0
TRIM43 TRIM43 Q96BQ3 Tripartite motif-containing protein 43 chr2 Not Cancer Driver No 1 hippie, biogrid 48 28 7 7 0
TRMU TRMU O75648 Mitochondrial tRNA-specific 2-thiouridylase 1 chr22 Not Cancer Driver No 1 hippie, biogrid 40 28 5 5 2
UPP1_ENST00000395564 UPP1 Q16831 Uridine phosphorylase 1 chr7 Not Cancer Driver No 1 hippie, biogrid 47 13 3 3 0
UQCRFS1 UQCRFS1 P47985 Cytochrome b-c1 complex subunit Rieske, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 43 47 4 4 1
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
YARS2 YARS2 Q9Y2Z4 Tyrosine--tRNA ligase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 59 62 11 11 2