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PPIE_ENST00000324379 ,PPIE ,Q9UNP9
  • Uniprot Accession= Q9UNP9
  • Ensembl Transcript= ENST00000324379.9
  • Uniprot Name= PPIE
  • Name= Peptidyl-prolyl cis-trans isomerase E
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 31
  • Number of Interaction partner in biogrid: 81
  • Number of Interaction partner in hippie: 249
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACBD3 ACBD3 Q9H3P7 Golgi resident protein GCP60 chr1 Not Cancer Driver No 2 hippie, biogrid 59 350 40 40 0
ACIN1 ACIN1 Q9UKV3 Apoptotic chromatin condensation inducer in the nucleus chr14 Not Cancer Driver No 1 hippie 157 1294 155 155 0
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ADSL ADSL P30566 Adenylosuccinate lyase chr22 Not Cancer Driver No 1 hippie 68 36 9 9 27
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 Census Yes 1 hippie 474 2281 268 268 1
AP2A2_ENST00000448903 AP2A2 O94973 AP-2 complex subunit alpha-2 chr11 Not Cancer Driver No 1 hippie 100 145 12 12 0
AQR AQR O60306 RNA helicase aquarius chr15 Not Cancer Driver No 5 intact, hippie, biogrid 201 297 31 31 0
ARHGEF11_ENST00000361409 ARHGEF11 O15085 Rho guanine nucleotide exchange factor 11 chr1 Not Cancer Driver No 1 hippie, biogrid 213 1036 138 138 0
ARL2 ARL2 P36404 ADP-ribosylation factor-like protein 2 chr11 Not Cancer Driver No 1 biogrid 19 0 0 0 1
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
BCAS2 BCAS2 O75934 Pre-mRNA-splicing factor SPF27 chr1 Not Cancer Driver No 3 hippie, biogrid 30 55 5 5 0
BDH2 BDH2 Q9BUT1 3-hydroxybutyrate dehydrogenase type 2 chr4 Not Cancer Driver No 1 hippie, biogrid 24 22 1 1 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 hippie 50 150 30 30 0
BRAP BRAP Q7Z569 BRCA1-associated protein chr12 Not Cancer Driver No 1 hippie 70 192 24 24 0
BUD31 BUD31 P41223 Protein BUD31 homolog chr7 Not Cancer Driver No 3 intact, hippie, biogrid 20 32 4 4 0
CCDC12_ENST00000425441 CCDC12 Q8WUD4 Coiled-coil domain-containing protein 12 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 12 168 12 12 0
CDC40 CDC40 O60508 Pre-mRNA-processing factor 17 chr6 Not Cancer Driver No 1 hippie, biogrid 79 214 27 27 1
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 2 hippie, biogrid 100 618 77 77 0
CEBPZ CEBPZ Q03701 CCAAT/enhancer-binding protein zeta chr2 Not Cancer Driver No 1 hippie 95 488 44 44 0
CFDP1 CFDP1 Q9UEE9 Craniofacial development protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 21 273 18 18 0
CHD9_ENST00000398510 CHD9 Q3L8U1 Chromodomain-helicase-DNA-binding protein 9 chr16 Not Cancer Driver No 1 hippie 301 1653 162 162 0
CHTF8_ENST00000398235 CHTF8 P0CG13 Chromosome transmission fidelity protein 8 homolog chr16 Not Cancer Driver No 3 intact, hippie, biogrid 13 7 0 0 0
CPSF4 CPSF4 O95639 Cleavage and polyadenylation specificity factor subunit 4 chr7 Not Cancer Driver No 1 hippie 36 89 11 11 0
CRNKL1 CRNKL1 Q9BZJ0 Crooked neck-like protein 1 chr20 Census, Compendium Yes 4 intact, hippie, biogrid 123 241 38 38 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 hippie 44 46 3 3 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CTNNBL1 CTNNBL1 Q8WYA6 Beta-catenin-like protein 1 chr20 Not Cancer Driver No 1 biogrid 72 158 24 24 0
CWC15 CWC15 Q9P013 Spliceosome-associated protein CWC15 homolog chr11 Not Cancer Driver No 1 hippie, biogrid 23 204 21 21 0
CWF19L1 CWF19L1 Q69YN2 CWF19-like protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 59 69 9 9 0
CWF19L2 CWF19L2 Q2TBE0 CWF19-like protein 2 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 119 615 83 83 0
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 Not Cancer Driver No 1 hippie 91 362 48 48 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 Not Cancer Driver No 1 hippie 72 342 30 30 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX Census, Compendium Yes 1 hippie 133 301 47 47 18
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 Census Yes 1 hippie 74 225 23 23 0
DDX54_ENST00000306014 DDX54 Q8TDD1 ATP-dependent RNA helicase DDX54 chr12 Not Cancer Driver No 1 hippie 113 458 52 52 0
DDX6 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 Census, Compendium Yes 1 hippie 44 129 7 7 5
DHX15 DHX15 O43143 ATP-dependent RNA helicase DHX15 chr4 Not Cancer Driver No 1 hippie 110 180 30 30 0
DHX35 DHX35 Q9H5Z1 Probable ATP-dependent RNA helicase DHX35 chr20 Not Cancer Driver No 2 hippie, biogrid 91 47 6 6 0
DHX8 DHX8 Q14562 ATP-dependent RNA helicase DHX8 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 138 490 72 72 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 Compendium Yes 1 hippie 182 331 42 42 0
DNAJC17 DNAJC17 Q9NVM6 DnaJ homolog subfamily C member 17 chr15 Not Cancer Driver No 1 hippie, biogrid 39 209 28 28 0
DNAJC9 DNAJC9 Q8WXX5 DnaJ homolog subfamily C member 9 chr10 Not Cancer Driver No 1 hippie, biogrid 28 126 15 15 0
DNASE1L2_ENST00000567494 DNASE1L2 Q92874 Deoxyribonuclease-1-like 2 chr16 Not Cancer Driver No 1 hippie, biogrid 23 15 1 1 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 97 437 58 58 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 hippie 505 495 62 62 21
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 hippie 109 100 14 14 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 2 hippie, biogrid 132 179 30 30 3
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 Not Cancer Driver No 1 hippie 50 57 6 6 1
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 Not Cancer Driver No 1 hippie 30 17 3 3 0
ELAVL2_ENST00000544538 ELAVL2 Q12926 ELAV-like protein 2 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 116 96 28 28 0
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 Census, Compendium Yes 1 hippie 92 208 22 22 2
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESS2 ESS2 Q96DF8 Splicing factor ESS-2 homolog chr22 Not Cancer Driver No 1 hippie 71 458 68 68 0
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie 94 646 93 93 0
EXOSC2 EXOSC2 Q13868 Exosome complex component RRP4 chr9 Not Cancer Driver No 1 hippie 21 47 6 6 2
FASTK FASTK Q14296 Fas-activated serine/threonine kinase chr7 Not Cancer Driver No 1 hippie 65 143 12 12 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 hippie 173 241 26 26 37
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 1 hippie 56 20 3 3 0
FUS FUS P35637 RNA-binding protein FUS chr16 Census Yes 1 hippie 51 524 51 51 20
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 1 hippie 68 388 42 42 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GCFC2 GCFC2 P16383 Intron Large complex component GCFC2 chr2 Not Cancer Driver No 1 hippie, biogrid 83 351 40 40 0
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 Not Cancer Driver No 1 hippie 45 24 2 2 16
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 hippie 115 854 96 96 0
GPATCH1 GPATCH1 Q9BRR8 G patch domain-containing protein 1 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 114 808 92 92 0
GSN GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 hippie 76 316 28 28 2
GTF2E1 GTF2E1 P29083 General transcription factor IIE subunit 1 chr3 Not Cancer Driver No 1 biogrid 71 264 48 48 0
GTSE1 GTSE1 Q9NYZ3 G2 and S phase-expressed protein 1 chr22 Not Cancer Driver No 1 hippie 91 660 85 85 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie 70 290 58 58 4
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 Census, Compendium Yes 1 hippie 68 255 41 41 0
HNRNPA3 HNRNPA3 P51991 Heterogeneous nuclear ribonucleoprotein A3 chr2 Not Cancer Driver No 1 hippie 46 285 37 37 0
HNRNPCL1 HNRNPCL1 O60812 Heterogeneous nuclear ribonucleoprotein C-like 1 chr1 Not Cancer Driver No 1 hippie, biogrid 142 203 87 87 0
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 Not Cancer Driver No 2 hippie, biogrid 42 227 35 35 0
HNRNPF_ENST00000356053 HNRNPF P52597 Heterogeneous nuclear ribonucleoprotein F chr10 Not Cancer Driver No 1 hippie 65 105 18 18 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 Not Cancer Driver No 1 hippie 75 302 59 59 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HNRNPM HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 hippie 108 463 67 67 0
HNRNPR_ENST00000374612 HNRNPR O43390 Heterogeneous nuclear ribonucleoprotein R chr1 Not Cancer Driver No 1 hippie 67 304 25 25 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 hippie 77 504 45 45 0
HNRNPUL1 HNRNPUL1 Q9BUJ2 Heterogeneous nuclear ribonucleoprotein U-like protein 1 chr19 Not Cancer Driver No 1 hippie 100 535 49 49 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 100 254 43 43 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie 73 282 35 35 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 61 82 6 6 2
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
IGF2BP3 IGF2BP3 O00425 Insulin-like growth factor 2 mRNA-binding protein 3 chr7 Not Cancer Driver No 1 hippie 79 264 40 40 0
IK IK Q13123 Protein Red chr5 Not Cancer Driver No 1 hippie 61 482 50 50 0
ILF2 ILF2 Q12905 Interleukin enhancer-binding factor 2 chr1 Not Cancer Driver No 1 hippie, biogrid 36 92 9 9 0
INKA2 INKA2 Q9NTI7 PAK4-inhibitor INKA2 chr1 Not Cancer Driver No 1 hippie 41 271 38 38 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 hippie 183 351 35 35 0
ISY1-RAB43 ISY1-RAB43 Q9ULR0-1 Isoform 2 of Pre-mRNA-splicing factor ISY1 homolog chr3 Not Cancer Driver No 1 biogrid 41 223 33 33 0
ISY1_ENST00000393295 ISY1 Q9ULR0 Pre-mRNA-splicing factor ISY1 homolog chr3 Not Cancer Driver No 5 intact, hippie, biogrid 29 171 18 18 0
KIAA1143 KIAA1143 Q96AT1 Uncharacterized protein KIAA1143 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 11 154 11 11 0
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 Census, Compendium Yes 1 hippie 446 3145 338 338 0
KPNA2_ENST00000330459 KPNA2 P52292 Importin subunit alpha-1 chr17 Not Cancer Driver No 1 hippie 74 129 18 18 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
KTN1 KTN1 Q86UP2 Kinectin chr14 Census Yes 1 hippie 138 964 102 102 0
LANCL2 LANCL2 Q9NS86 LanC-like protein 2 chr7 Not Cancer Driver No 1 hippie 71 44 5 5 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 131 18 2 2 1
LRRFIP2 LRRFIP2 Q9Y608 Leucine-rich repeat flightless-interacting protein 2 chr3 Not Cancer Driver No 1 hippie 75 584 62 62 0
LUC7L LUC7L Q9NQ29 Putative RNA-binding protein Luc7-like 1 chr16 Not Cancer Driver No 1 hippie 50 254 41 41 0
LUC7L2 LUC7L2 Q9Y383 Putative RNA-binding protein Luc7-like 2 chr7 Not Cancer Driver No 1 hippie 59 262 45 45 0
MAGOH MAGOH P61326 Protein mago nashi homolog chr1 Not Cancer Driver No 1 hippie 15 6 0 0 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 hippie 92 376 49 49 1
MATR3_ENST00000509990 MATR3 P43243 Matrin-3 chr5 Not Cancer Driver No 1 hippie 98 611 68 68 3
MAX MAX P61244 Protein max chr14 Census, Compendium Yes 1 biogrid 45 160 45 45 9
MCM6 MCM6 Q14566 DNA replication licensing factor MCM6 chr2 Not Cancer Driver No 1 hippie 101 122 13 13 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX Not Cancer Driver No 1 hippie, biogrid 75 483 74 74 46
MEX3C MEX3C Q5U5Q3 RNA-binding E3 ubiquitin-protein ligase MEX3C chr18 Not Cancer Driver No 1 hippie 54 475 32 32 0
MTMR4 MTMR4 Q9NYA4 Myotubularin-related protein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 147 474 59 59 0
MTREX MTREX P42285 Exosome RNA helicase MTR4 chr5 Not Cancer Driver No 1 hippie 117 160 15 15 0
NCL NCL P19338 Nucleolin chr2 Not Cancer Driver No 1 hippie 85 569 68 68 0
NCOA6 NCOA6 Q14686 Nuclear receptor coactivator 6 chr20 Not Cancer Driver No 1 hippie 242 1941 219 219 0
NKAPD1_ENST00000420986 NKAPD1 Q6ZUT1 Uncharacterized protein NKAPD1 chr11 Not Cancer Driver No 1 intact, hippie 35 261 31 31 0
OR2T1 OR2T1 O43869 Olfactory receptor 2T1 chr1 Not Cancer Driver No 1 hippie 130 0 0 0 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 hippie 100 317 55 55 0
PATL1 PATL1 Q86TB9 Protein PAT1 homolog 1 chr11 Not Cancer Driver No 1 hippie 79 499 49 49 0
PAXBP1 PAXBP1 Q9Y5B6 PAX3- and PAX7-binding protein 1 chr21 Not Cancer Driver No 1 hippie 96 532 55 55 0
PCBP1 PCBP1 Q15365 Poly(rC)-binding protein 1 chr2 Census, Compendium Yes 1 hippie 65 166 24 24 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 Not Cancer Driver No 1 hippie 46 13 5 5 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 Census Yes 1 hippie 152 1665 134 134 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 30 22 3 3 1
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 Not Cancer Driver No 1 hippie 57 98 11 11 0
PHF13 PHF13 Q86YI8 PHD finger protein 13 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 52 158 25 25 0
PHYHIP PHYHIP Q92561 Phytanoyl-CoA hydroxylase-interacting protein chr8 Not Cancer Driver No 1 hippie, biogrid 44 25 4 4 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLRG1 PLRG1 O43660 Pleiotropic regulator 1 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 75 204 25 25 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 Not Cancer Driver No 1 hippie 53 177 23 23 4
PNN PNN Q9H307 Pinin chr14 Not Cancer Driver No 2 hippie, biogrid 94 700 90 90 0
PNO1 PNO1 Q9NRX1 RNA-binding protein PNO1 chr2 Not Cancer Driver No 1 hippie 30 85 10 10 0
POLL_ENST00000370169 POLL Q9UGP5 DNA polymerase lambda chr10 Not Cancer Driver No 1 hippie, biogrid 69 215 16 16 0
PPIE_ENST00000324379 PPIE Q9UNP9 Peptidyl-prolyl cis-trans isomerase E chr1 Not Cancer Driver No 1 biogrid 51 102 17 17 0
PPIL1 PPIL1 Q9Y3C6 Peptidyl-prolyl cis-trans isomerase-like 1 chr6 Not Cancer Driver No 1 hippie, biogrid 25 42 11 11 3
PPIL2_ENST00000335025 PPIL2 Q13356 RING-type E3 ubiquitin-protein ligase PPIL2 chr22 Not Cancer Driver No 1 hippie 64 212 19 19 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 Not Cancer Driver No 1 hippie 24 30 4 4 0
PRKAR2A PRKAR2A P13861 cAMP-dependent protein kinase type II-alpha regulatory subunit chr3 Not Cancer Driver No 1 hippie 37 149 13 13 0
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 Not Cancer Driver No 1 hippie 41 104 12 12 1
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 hippie 83 72 6 6 0
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 71 109 16 16 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PRPF6 PRPF6 O94906 Pre-mRNA-processing factor 6 chr20 Not Cancer Driver No 1 hippie 140 379 62 62 1
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 biogrid 110 201 19 19 0
PTBP3_ENST00000374255 PTBP3 O95758 Polypyrimidine tract-binding protein 3 chr9 Not Cancer Driver No 1 hippie 61 114 9 9 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 Not Cancer Driver No 1 hippie 16 38 2 2 0
RALY RALY Q9UKM9 RNA-binding protein Raly chr20 Not Cancer Driver No 1 hippie 58 187 32 32 0
RALYL_ENST00000521268 RALYL Q86SE5 RNA-binding Raly-like protein chr8 Not Cancer Driver No 2 hippie, biogrid 111 181 75 75 0
RBM17 RBM17 Q96I25 Splicing factor 45 chr10 Not Cancer Driver No 1 hippie 49 293 38 38 0
RBM22 RBM22 Q9NW64 Pre-mRNA-splicing factor RBM22 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 51 214 29 29 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 Not Cancer Driver No 1 hippie, biogrid 60 244 26 26 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RIOX1 RIOX1 Q9H6W3 Ribosomal oxygenase 1 chr14 Not Cancer Driver No 1 hippie 52 215 15 15 0
RNF138 RNF138 Q8WVD3 E3 ubiquitin-protein ligase RNF138 chr18 Not Cancer Driver No 1 hippie 44 34 6 6 0
RNPS1_ENST00000301730 RNPS1 Q15287 RNA-binding protein with serine-rich domain 1 chr16 Not Cancer Driver No 1 hippie 30 305 30 30 0
RPL10_ENST00000369817 RPL10 P27635 60S ribosomal protein L10 chrX Census, Compendium Yes 1 hippie 46 9 3 3 4
RPL12 RPL12 P30050 60S ribosomal protein L12 chr9 Not Cancer Driver No 1 hippie 13 75 6 6 0
RPL15_ENST00000413699 RPL15 P61313 60S ribosomal protein L15 chr3 Not Cancer Driver No 1 hippie 18 84 9 9 0
RPL18 RPL18 Q07020 60S ribosomal protein L18 chr19 Not Cancer Driver No 1 hippie 16 98 6 6 0
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 Not Cancer Driver No 1 hippie 14 29 4 4 0
RPL27A RPL27A P46776 60S ribosomal protein L27a chr11 Not Cancer Driver No 1 hippie 7 56 2 2 0
RPL27_ENST00000253788 RPL27 P61353 60S ribosomal protein L27 chr17 Not Cancer Driver No 1 hippie 21 13 3 3 0
RPL28_ENST00000559463 RPL28 P46779 60S ribosomal protein L28 chr19 Not Cancer Driver No 1 hippie 29 115 24 24 0
RPL3 RPL3 P39023 60S ribosomal protein L3 chr22 Not Cancer Driver No 1 hippie 34 79 3 3 0
RPL30 RPL30 P62888 60S ribosomal protein L30 chr8 Not Cancer Driver No 1 hippie 4 11 0 0 0
RPL35A RPL35A P18077 60S ribosomal protein L35a chr3 Not Cancer Driver No 1 hippie 9 25 0 0 1
RPL4 RPL4 P36578 60S ribosomal protein L4 chr15 Not Cancer Driver No 1 hippie 49 222 31 31 0
RPL6 RPL6 Q02878 60S ribosomal protein L6 chr12 Not Cancer Driver No 1 hippie 41 159 24 24 0
RPL7 RPL7 P18124 60S ribosomal protein L7 chr8 Not Cancer Driver No 1 hippie 24 40 4 4 0
RPL8_ENST00000528957 RPL8 P62917 60S ribosomal protein L8 chr8 Not Cancer Driver No 1 hippie 32 115 17 17 0
RPL9 RPL9 Q53Z07 60S ribosomal protein L9 chr4 Not Cancer Driver No 1 hippie 30 3 0 0 0
RPLP0_ENST00000228306 RPLP0 P05388 60S acidic ribosomal protein P0 chr12 Not Cancer Driver No 1 hippie 44 36 4 4 0
RPS26_ENST00000646449 RPS26 P62854 40S ribosomal protein S26 chr12 Not Cancer Driver No 1 hippie 9 52 5 5 2
RPS3A RPS3A P61247 40S ribosomal protein S3a chr4 Compendium Yes 1 hippie 21 85 5 5 0
RPS4X RPS4X P62701 40S ribosomal protein S4, X isoform chrX Not Cancer Driver No 1 hippie 32 35 6 6 0
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 Not Cancer Driver No 1 hippie 38 150 25 25 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 Not Cancer Driver No 1 hippie 29 39 7 7 0
RPS8 RPS8 P62241 40S ribosomal protein S8 chr1 Not Cancer Driver No 1 hippie 23 81 7 7 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 Not Cancer Driver No 1 hippie 23 34 5 5 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 hippie 74 513 48 48 0
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 Not Cancer Driver No 1 hippie 71 685 63 63 0
SEC24B_ENST00000265175 SEC24B O95487 Protein transport protein Sec24B chr4 Not Cancer Driver No 1 hippie 135 526 55 55 0
SF1_ENST00000377390 SF1 Q15637 Splicing factor 1 chr11 Not Cancer Driver No 1 hippie 110 627 106 106 0
SF3A1 SF3A1 Q15459 Splicing factor 3A subunit 1 chr22 Not Cancer Driver No 1 hippie 82 631 67 67 0
SF3A2 SF3A2 Q15428 Splicing factor 3A subunit 2 chr19 Not Cancer Driver No 1 hippie, biogrid 30 382 21 21 0
SF3B2 SF3B2 Q13435 Splicing factor 3B subunit 2 chr11 Not Cancer Driver No 1 hippie 110 804 105 105 0
SFN SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 27 75 9 9 0
SLC10A2 SLC10A2 Q12908 Ileal sodium/bile acid cotransporter chr13 Not Cancer Driver No 1 hippie, biogrid 119 23 15 15 2
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SLC19A2 SLC19A2 O60779 Thiamine transporter 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 61 17 6 6 3
SLC25A21 SLC25A21 Q9BQT8 Mitochondrial 2-oxodicarboxylate carrier chr14 Not Cancer Driver No 3 intact, hippie, biogrid 44 0 0 0 1
SLU7 SLU7 O95391 Pre-mRNA-splicing factor SLU7 chr5 Not Cancer Driver No 1 hippie 75 436 63 63 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SMC1A SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX Census, Compendium Yes 1 hippie, biogrid 200 717 114 114 21
SMC3 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 Not Cancer Driver No 1 hippie, biogrid 149 605 70 70 0
SNIP1 SNIP1 Q8TAD8 Smad nuclear-interacting protein 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 58 285 40 40 1
SNRNP40 SNRNP40 Q96DI7 U5 small nuclear ribonucleoprotein 40 kDa protein chr1 Not Cancer Driver No 2 hippie, biogrid 41 50 10 10 0
SNRPA1 SNRPA1 P09661 U2 small nuclear ribonucleoprotein A' chr15 Not Cancer Driver No 2 intact, hippie, biogrid 33 93 14 14 0
SNRPB2_ENST00000377943 SNRPB2 P08579 U2 small nuclear ribonucleoprotein B'' chr20 Not Cancer Driver No 1 hippie, biogrid 18 100 7 7 0
SNRPD2_ENST00000588301 SNRPD2 P62316 Small nuclear ribonucleoprotein Sm D2 chr19 Not Cancer Driver No 1 hippie 19 67 12 12 0
SNRPD3 SNRPD3 P62318 Small nuclear ribonucleoprotein Sm D3 chr22 Not Cancer Driver No 1 hippie, biogrid 20 43 13 13 0
SNRPE SNRPE P62304 Small nuclear ribonucleoprotein E chr1 Not Cancer Driver No 2 intact, hippie, biogrid 16 0 0 0 1
SNRPF SNRPF P62306 Small nuclear ribonucleoprotein F chr12 Not Cancer Driver No 2 intact, hippie, biogrid 4 10 0 0 0
SNRPG_ENST00000272348 SNRPG P62308 Small nuclear ribonucleoprotein G chr2 Not Cancer Driver No 2 hippie, biogrid 8 9 3 3 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 3 hippie, biogrid 62 488 56 56 0
SPANXN2 SPANXN2 Q5MJ10 Sperm protein associated with the nucleus on the X chromosome N2 chrX Not Cancer Driver No 1 hippie, biogrid 106 180 106 106 0
SPATS2_ENST00000552918 SPATS2 Q86XZ4 Spermatogenesis-associated serine-rich protein 2 chr12 Not Cancer Driver No 1 hippie 62 392 52 52 0
SPECC1 SPECC1 Q5M775 Cytospin-B chr17 Census Yes 1 hippie 165 833 133 133 0
SRRM1 SRRM1 Q8IYB3 Serine/arginine repetitive matrix protein 1 chr1 Not Cancer Driver No 1 hippie 129 795 122 122 0
SRRM2 SRRM2 Q9UQ35 Serine/arginine repetitive matrix protein 2 chr16 Not Cancer Driver No 1 hippie 433 2748 431 431 0
SRSF11 SRSF11 Q05519 Serine/arginine-rich splicing factor 11 chr1 Not Cancer Driver No 1 hippie 63 362 55 55 0
SRSF2 SRSF2 Q01130 Serine/arginine-rich splicing factor 2 chr17 Census, Compendium Yes 1 hippie 38 219 38 38 0
SRSF3_ENST00000620941 SRSF3 P84103 Serine/arginine-rich splicing factor 3 chr6 Census Yes 1 hippie 31 125 27 27 0
SRSF4 SRSF4 Q08170 Serine/arginine-rich splicing factor 4 chr1 Not Cancer Driver No 1 hippie 67 409 55 55 0
SRSF5_ENST00000557154 SRSF5 Q13243 Serine/arginine-rich splicing factor 5 chr14 Not Cancer Driver No 1 hippie 50 189 40 40 0
SRSF6 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 Not Cancer Driver No 1 hippie 69 259 49 49 0
SRSF7 SRSF7 Q16629 Serine/arginine-rich splicing factor 7 chr2 Not Cancer Driver No 2 hippie, biogrid 40 175 26 26 0
SRSF9 SRSF9 Q13242 Serine/arginine-rich splicing factor 9 chr12 Not Cancer Driver No 1 hippie 20 111 8 8 0
SSB SSB P05455 Lupus La protein chr2 Not Cancer Driver No 1 hippie 39 181 18 18 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SYF2 SYF2 O95926 Pre-mRNA-splicing factor SYF2 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 26 173 17 17 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 Not Cancer Driver No 1 hippie 93 285 39 39 0
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 Not Cancer Driver No 1 hippie, biogrid 87 331 39 39 0
THOC2_ENST00000355725 THOC2 Q8NI27 THO complex subunit 2 chrX Not Cancer Driver No 1 hippie 287 549 103 103 4
THOC5_ENST00000397872 THOC5 Q13769 THO complex subunit 5 homolog chr22 Not Cancer Driver No 1 hippie 88 173 25 25 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 Not Cancer Driver No 1 hippie 198 1350 151 151 0
TRA2B TRA2B P62995 Transformer-2 protein homolog beta chr3 Not Cancer Driver No 1 hippie 59 244 54 54 0
TRIM55 TRIM55 Q9BYV6 Tripartite motif-containing protein 55 chr8 Not Cancer Driver No 1 hippie, biogrid 134 276 78 78 0
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 Not Cancer Driver No 1 hippie, biogrid 47 71 13 13 0
TRMT61B TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 3 intact, hippie, biogrid 48 123 10 10 0
TSSC4 TSSC4 Q9Y5U2 Protein TSSC4 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 35 326 35 35 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie 40 63 11 11 5
U2AF1L4_ENST00000412391 U2AF1L4 Q8WU68 Splicing factor U2AF 26 kDa subunit chr19 Not Cancer Driver No 1 hippie 28 49 6 6 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 hippie, biogrid 78 191 28 28 0
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 Not Cancer Driver No 1 hippie 146 329 36 36 0
USB1 USB1 Q9BQ65 U6 snRNA phosphodiesterase 1 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 28 76 5 5 0
WDR70 WDR70 Q9NW82 WD repeat-containing protein 70 chr5 Not Cancer Driver No 1 biogrid 97 363 57 57 0
WDR82 WDR82 Q6UXN9 WD repeat-containing protein 82 chr3 Not Cancer Driver No 1 hippie 35 0 0 0 0
WDR83 WDR83 Q9BRX9 WD repeat domain-containing protein 83 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 28 35 3 3 0
XAB2 XAB2 Q9HCS7 Pre-mRNA-splicing factor SYF1 chr19 Not Cancer Driver No 6 intact, hippie, biogrid 128 127 17 17 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 Not Cancer Driver No 1 hippie 87 118 11 11 0
YJU2 YJU2 Q9BW85 Splicing factor YJU2 chr19 Not Cancer Driver No 1 intact, hippie 29 233 13 13 0
YTHDC1_ENST00000344157 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie 137 597 117 117 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 hippie 22 109 4 4 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 hippie 26 77 9 9 2
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 30 81 10 10 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 2 hippie, biogrid 139 929 134 134 0
ZCCHC10 ZCCHC10 Q8TBK6 Zinc finger CCHC domain-containing protein 10 chr5 Not Cancer Driver No 1 hippie, biogrid 12 144 11 11 0
ZNF326 ZNF326 Q5BKZ1 DBIRD complex subunit ZNF326 chr1 Not Cancer Driver No 1 hippie 64 490 53 53 0
ZNF830 ZNF830 Q96NB3 Zinc finger protein 830 chr17 Not Cancer Driver No 5 intact, hippie, biogrid 39 312 37 37 0