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POU2F1_ENST00000541643 ,POU2F1 ,P14859
  • Uniprot Accession= P14859
  • Ensembl Transcript= ENST00000541643.7
  • Uniprot Name= POU2F1
  • Name= POU domain, class 2, transcription factor 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 52
  • Number of Interaction partner in hippie: 149
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ALOXE3_ENST00000448843 ALOXE3 Q9BYJ1 Hydroperoxide isomerase ALOXE3 chr17 Not Cancer Driver No 1 hippie, biogrid 108 69 13 13 6
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARPC3 ARPC3 O15145 Actin-related protein 2/3 complex subunit 3 chr12 Not Cancer Driver No 1 hippie 17 26 6 6 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 1 hippie 49 154 13 13 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 46 122 22 22 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 Not Cancer Driver No 1 hippie, biogrid 65 451 58 58 0
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie 200 115 29 29 31
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 60 85 8 8 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 hippie, biogrid 29 195 9 9 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 Not Cancer Driver No 1 hippie, biogrid 10 11 2 2 1
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 Census Yes 1 hippie 96 384 49 49 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 hippie 50 150 30 30 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 2 hippie, biogrid 224 1458 174 174 35
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
CDK11B CDK11B P21127 Cyclin-dependent kinase 11B chr1 Not Cancer Driver No 1 hippie 74 501 35 35 0
CEBPE CEBPE Q15744 CCAAT/enhancer-binding protein epsilon chr14 Not Cancer Driver No 1 hippie 56 257 53 53 0
CMTM8 CMTM8 Q8IZV2 CKLF-like MARVEL transmembrane domain-containing protein 8 chr3 Not Cancer Driver No 1 hippie, biogrid 23 9 1 1 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 Census Yes 1 hippie 25 277 23 23 0
CREM_ENST00000429130 CREM Q03060 cAMP-responsive element modulator chr10 Not Cancer Driver No 1 hippie 32 289 26 26 0
EAF2 EAF2 Q96CJ1 ELL-associated factor 2 chr3 Not Cancer Driver No 1 hippie, biogrid 31 199 22 22 0
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 hippie, biogrid 109 100 14 14 0
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 Not Cancer Driver No 1 hippie, biogrid 74 121 17 17 3
ELF2 ELF2 Q15723 ETS-related transcription factor Elf-2 chr4 Not Cancer Driver No 1 hippie 59 423 43 43 0
ELK3 ELK3 P41970 ETS domain-containing protein Elk-3 chr12 Not Cancer Driver No 1 hippie 58 163 16 16 0
EPCAM EPCAM P16422 Epithelial cell adhesion molecule chr2 Not Cancer Driver No 1 hippie, biogrid 40 25 2 2 1
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
FBXO25 FBXO25 Q8TCJ0 F-box only protein 25 chr8 Not Cancer Driver No 1 hippie 33 20 0 0 0
FDXR_ENST00000293195 FDXR P22570 NADPH:adrenodoxin oxidoreductase, mitochondrial chr17 Not Cancer Driver No 2 hippie, biogrid 68 102 14 14 4
FEV FEV Q99581 Protein FEV chr2 Census Yes 1 hippie 15 55 0 0 0
FGB FGB P02675 Fibrinogen beta chain chr4 Not Cancer Driver No 2 hippie, biogrid 89 143 29 29 7
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 Not Cancer Driver No 1 hippie 362 1183 170 170 19
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 Not Cancer Driver No 1 hippie 33 411 24 24 32
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 Not Cancer Driver No 1 hippie 63 369 33 33 1
FOXL1 FOXL1 Q12952 Forkhead box protein L1 chr16 Not Cancer Driver No 1 hippie 62 212 26 26 0
FOXS1 FOXS1 O43638 Forkhead box protein S1 chr20 Not Cancer Driver No 1 hippie 67 226 41 41 0
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie 39 24 3 3 0
GPC5 GPC5 P78333 Glypican-5 chr13 Census Yes 1 hippie, biogrid 239 117 56 56 0
HCFC1 HCFC1 P51610 Host cell factor 1 chrX Not Cancer Driver No 1 hippie 280 1345 181 181 1
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 47 135 10 10 0
HIVEP1 HIVEP1 P15822 Zinc finger protein 40 chr6 Not Cancer Driver No 1 hippie 344 2238 292 292 0
HMGA1 HMGA1 P17096 High mobility group protein HMG-I/HMG-Y chr6 Census Yes 1 hippie 6 107 6 6 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 Not Cancer Driver No 1 hippie 38 207 38 38 0
HNF1A_ENST00000257555 HNF1A P20823 Hepatocyte nuclear factor 1-alpha chr12 Census, Compendium Yes 1 hippie 96 569 80 80 42
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie, biogrid 51 169 29 29 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 Not Cancer Driver No 1 hippie, biogrid 75 302 59 59 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 hippie, biogrid 77 504 45 45 0
HOXB13 HOXB13 Q92826 Homeobox protein Hox-B13 chr17 Not Cancer Driver No 1 hippie 61 179 37 37 1
HOXC4 HOXC4 P09017 Homeobox protein Hox-C4 chr12 Not Cancer Driver No 1 hippie 40 227 33 33 0
HOXC9 HOXC9 P31274 Homeobox protein Hox-C9 chr12 Not Cancer Driver No 1 hippie 30 143 14 14 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 hippie, biogrid 27 15 3 3 11
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie, biogrid 106 257 37 37 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 93 286 38 38 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie, biogrid 80 351 24 24 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie, biogrid 73 282 35 35 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 2 hippie, biogrid 149 251 52 52 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 67 283 26 26 2
IRF9 IRF9 Q00978 Interferon regulatory factor 9 chr14 Not Cancer Driver No 1 hippie 48 204 15 15 0
KCTD17 KCTD17 Q8N5Z5 BTB/POZ domain-containing protein KCTD17 chr22 Not Cancer Driver No 1 hippie, biogrid 23 187 14 14 1
KLF16 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 hippie 13 204 8 8 0
KLF8 KLF8 O95600 Krueppel-like factor 8 chrX Not Cancer Driver No 1 hippie 71 270 53 53 0
KRT8_ENST00000546897 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie, biogrid 65 221 37 37 3
LIFR_ENST00000453190 LIFR P42702 Leukemia inhibitory factor receptor chr5 Census, Compendium Yes 1 hippie 247 259 56 56 1
LMNB1 LMNB1 P20700 Lamin-B1 chr5 Not Cancer Driver No 1 hippie 60 404 42 42 4
MAGEA10 MAGEA10 P43363 Melanoma-associated antigen 10 chrX Not Cancer Driver No 3 hippie, biogrid 114 169 57 57 0
MLLT10_ENST00000377059 MLLT10 P55197 Protein AF-10 chr10 Census Yes 1 hippie 133 835 94 94 0
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 Not Cancer Driver No 1 hippie 23 64 2 2 0
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 Not Cancer Driver No 1 hippie 39 197 16 16 7
NCOR2 NCOR2 Q9Y618 Nuclear receptor corepressor 2 chr12 Census, Compendium Yes 2 hippie, biogrid 373 2355 356 356 0
NFIC NFIC P08651 Nuclear factor 1 C-type chr19 Not Cancer Driver No 1 hippie 61 327 44 44 0
NFIX_ENST00000592199 NFIX Q14938 Nuclear factor 1 X-type chr19 Not Cancer Driver No 1 hippie 60 305 40 40 6
NFYA NFYA P23511 Nuclear transcription factor Y subunit alpha chr6 Not Cancer Driver No 1 hippie 43 187 29 29 0
NPAT NPAT Q14207 Protein NPAT chr11 Not Cancer Driver No 1 hippie 134 1149 113 113 0
NR2F1_ENST00000327111 NR2F1 P10589 COUP transcription factor 1 chr5 Not Cancer Driver No 1 hippie 67 110 6 6 4
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NT5C2_ENST00000404739 NT5C2 P49902 Cytosolic purine 5'-nucleotidase chr10 Census Yes 1 hippie, biogrid 57 85 8 8 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 hippie 119 320 34 34 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 Not Cancer Driver No 1 hippie 62 296 48 48 23
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 Not Cancer Driver No 1 hippie 72 337 56 56 38
PAX7_ENST00000420770 PAX7 P23759 Paired box protein Pax-7 chr1 Census Yes 1 hippie 97 401 77 77 1
PBX1 PBX1 P40424 Pre-B-cell leukemia transcription factor 1 chr1 Census Yes 1 hippie 82 290 57 57 0
PGAM5 PGAM5 Q96HS1 Serine/threonine-protein phosphatase PGAM5, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 32 102 12 12 0
PGR PGR P06401 Progesterone receptor chr11 Not Cancer Driver No 1 hippie 161 480 55 55 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie, biogrid 78 58 13 13 0
PKNOX1 PKNOX1 P55347 Homeobox protein PKNOX1 chr21 Not Cancer Driver No 1 hippie 60 279 36 36 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 Not Cancer Driver No 1 hippie 75 202 15 15 0
POGZ POGZ Q7Z3K3 Pogo transposable element with ZNF domain chr1 Not Cancer Driver No 1 hippie 157 746 78 78 0
POU2AF1 POU2AF1 Q16633 POU domain class 2-associating factor 1 chr11 Census Yes 1 hippie 59 181 45 45 0
POU2F1_ENST00000541643 POU2F1 P14859 POU domain, class 2, transcription factor 1 chr1 Not Cancer Driver No 1 hippie 95 433 50 50 0
POU6F2 POU6F2 P78424 POU domain, class 6, transcription factor 2 chr7 Not Cancer Driver No 1 hippie 165 571 144 144 1
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 Not Cancer Driver No 1 hippie, biogrid 11 24 3 3 0
PPIP5K2_ENST00000358359 PPIP5K2 O43314 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 chr5 Not Cancer Driver No 1 hippie 146 419 54 54 1
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie 538 421 61 61 2
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 hippie, biogrid 83 72 6 6 0
PRR13 PRR13 Q9NZ81 Proline-rich protein 13 chr12 Not Cancer Driver No 1 hippie, biogrid 6 148 6 6 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 Census, Compendium Yes 1 hippie 70 167 14 14 0
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RPL22L1 RPL22L1 Q6P5R6 60S ribosomal protein L22-like 1 chr3 Not Cancer Driver No 1 hippie, biogrid 16 22 4 4 0
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 hippie, biogrid 19 69 14 14 0
RPL37A RPL37A P61513 60S ribosomal protein L37a chr2 Not Cancer Driver No 1 hippie, biogrid 4 0 0 0 0
RPS14_ENST00000521466 RPS14 P62263 40S ribosomal protein S14 chr5 Not Cancer Driver No 1 hippie, biogrid 14 96 13 13 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 Not Cancer Driver No 1 hippie, biogrid 15 61 3 3 23
RPS24_ENST00000613865 RPS24 P62847 40S ribosomal protein S24 chr10 Not Cancer Driver No 1 hippie, biogrid 13 88 10 10 0
RPS4X RPS4X P62701 40S ribosomal protein S4, X isoform chrX Not Cancer Driver No 1 hippie, biogrid 32 35 6 6 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 Compendium Yes 1 hippie 90 184 26 26 0
S100A2_ENST00000368709 S100A2 P29034 Protein S100-A2 chr1 Not Cancer Driver No 1 hippie, biogrid 16 6 2 2 0
SCYL2_ENST00000360820 SCYL2 Q6P3W7 SCY1-like protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 103 328 29 29 0
SNAPC4 SNAPC4 Q5SXM2 snRNA-activating protein complex subunit 4 chr9 Not Cancer Driver No 1 hippie 143 1094 96 96 0
SNIP1 SNIP1 Q8TAD8 Smad nuclear-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 58 285 40 40 1
SNX24 SNX24 Q9Y343 Sorting nexin-24 chr5 Not Cancer Driver No 1 hippie 24 14 3 3 0
SOX15_ENST00000538513 SOX15 O60248 Protein SOX-15 chr17 Not Cancer Driver No 1 hippie 18 227 18 18 0
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 Compendium Yes 1 hippie 81 378 59 59 2
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SOX5 SOX5 P35711 Transcription factor SOX-5 chr12 Not Cancer Driver No 1 hippie 182 665 162 162 0
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 Not Cancer Driver No 1 hippie 130 744 118 118 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SP4 SP4 Q02446 Transcription factor Sp4 chr7 Not Cancer Driver No 1 hippie 95 532 71 71 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 hippie 63 332 44 44 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 Not Cancer Driver No 1 hippie, biogrid 311 869 123 123 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie, biogrid 110 152 15 15 19
STAT5A_ENST00000590949 STAT5A P42229 Signal transducer and activator of transcription 5A chr17 Not Cancer Driver No 1 hippie 89 125 14 14 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 Census, Compendium Yes 1 hippie 93 144 19 19 5
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie 74 270 39 39 0
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 Not Cancer Driver No 1 hippie 121 659 83 83 2
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TBP TBP P20226 TATA-box-binding protein chr6 Not Cancer Driver No 1 hippie 40 164 14 14 0
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 Not Cancer Driver No 1 hippie 52 157 24 24 1
TEAD2_ENST00000311227 TEAD2 Q15562 Transcriptional enhancer factor TEF-4 chr19 Not Cancer Driver No 1 hippie 66 220 31 31 0
TGM1 TGM1 P22735 Protein-glutamine gamma-glutamyltransferase K chr14 Not Cancer Driver No 1 hippie, biogrid 118 230 37 37 65
THRA THRA P10827 Thyroid hormone receptor alpha chr17 Not Cancer Driver No 1 hippie 69 207 30 30 2
TLE4_ENST00000376552 TLE4 Q04727 Transducin-like enhancer protein 4 chr9 Not Cancer Driver No 1 hippie 172 381 92 92 0
TLX2 TLX2 O43763 T-cell leukemia homeobox protein 2 chr2 Not Cancer Driver No 1 hippie 24 220 15 15 0
TLX3 TLX3 O43711 T-cell leukemia homeobox protein 3 chr5 Census Yes 1 hippie 40 179 24 24 0
TNF TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 2 hippie, biogrid 24 45 3 3 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 Not Cancer Driver No 1 hippie, biogrid 85 49 7 7 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TUBA1B TUBA1B P68363 Tubulin alpha-1B chain chr12 Not Cancer Driver No 1 hippie, biogrid 41 52 9 9 0
TXNRD1 TXNRD1 Q16881 Thioredoxin reductase 1, cytoplasmic chr12 Not Cancer Driver No 1 hippie 85 67 9 9 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 Not Cancer Driver No 1 hippie 64 102 16 16 14
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 Not Cancer Driver No 2 hippie, biogrid 87 118 11 11 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 2 hippie, biogrid 66 140 12 12 0
ZC3H10 ZC3H10 Q96K80 Zinc finger CCCH domain-containing protein 10 chr12 Not Cancer Driver No 1 hippie 41 336 31 31 0
ZFHX3_ENST00000268489 ZFHX3 Q15911 Zinc finger homeobox protein 3 chr16 Census, Compendium Yes 1 hippie 501 2555 337 337 0
ZMYM6 ZMYM6 O95789 Zinc finger MYM-type protein 6 chr1 Not Cancer Driver No 1 hippie 125 229 29 29 0
ZNF330 ZNF330 Q9Y3S2 Zinc finger protein 330 chr4 Not Cancer Driver No 1 hippie, biogrid 44 127 19 19 0