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PMVK ,PMVK ,Q15126
  • Uniprot Accession= Q15126
  • Ensembl Transcript= ENST00000368467.3
  • Uniprot Name= PMVK
  • Name= Phosphomevalonate kinase
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 20
  • Number of Interaction partner in biogrid: 46
  • Number of Interaction partner in hippie: 53
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ARL6IP6 ARL6IP6 Q8N6S5 ADP-ribosylation factor-like protein 6-interacting protein 6 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 28 77 7 7 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 Not Cancer Driver No 1 hippie, biogrid 69 14 5 5 0
CCT8L2 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 216 104 46 46 0
CENPH CENPH Q9H3R5 Centromere protein H chr5 Not Cancer Driver No 1 hippie, biogrid 28 85 7 7 0
CENPW_ENST00000368328 CENPW Q5EE01 Centromere protein W chr6 Not Cancer Driver No 1 hippie, biogrid 9 5 1 1 0
DDIT4L DDIT4L Q96D03 DNA damage-inducible transcript 4-like protein chr4 Not Cancer Driver No 1 hippie 48 5 3 3 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie, biogrid 44 37 2 2 0
EEF1AKMT3 EEF1AKMT3 Q96AZ1 EEF1A lysine methyltransferase 3 chr12 Not Cancer Driver No 1 hippie 23 33 1 1 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FDPS_ENST00000368356 FDPS P14324 Farnesyl pyrophosphate synthase chr1 Not Cancer Driver No 1 biogrid 66 0 0 0 1
FGB FGB P02675 Fibrinogen beta chain chr4 Not Cancer Driver No 2 intact, hippie, biogrid 89 143 29 29 7
FSD1 FSD1 Q9BTV5 Fibronectin type III and SPRY domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 66 90 17 17 0
FYTTD1 FYTTD1 Q96QD9 UAP56-interacting factor chr3 Not Cancer Driver No 1 hippie, biogrid 51 281 48 48 0
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 hippie, biogrid 56 35 5 5 0
GSX1 GSX1 Q9H4S2 GS homeobox 1 chr13 Not Cancer Driver No 1 hippie, biogrid 26 137 14 14 0
GTF2E2 GTF2E2 P29084 Transcription initiation factor IIE subunit beta chr8 Not Cancer Driver No 2 intact, hippie, biogrid 34 130 16 16 2
HNRNPCL2 HNRNPCL2 B2RXH8 Heterogeneous nuclear ribonucleoprotein C-like 2 chr1 Not Cancer Driver No 1 hippie, biogrid 51 199 41 41 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 intact, hippie 36 25 6 6 0
HSPB8 HSPB8 Q9UJY1 Heat shock protein beta-8 chr12 Not Cancer Driver No 1 hippie, biogrid 40 130 31 31 5
KCTD14 KCTD14 Q9BQ13 BTB/POZ domain-containing protein KCTD14 chr11 Not Cancer Driver No 1 hippie, biogrid 45 37 3 3 0
LGI1 LGI1 O95970 Leucine-rich glioma-inactivated protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 87 3 1 1 17
LRRC29 LRRC29 Q8WV35 Leucine-rich repeat-containing protein 29 chr16 Not Cancer Driver No 1 hippie, biogrid 20 47 2 2 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MBD5 MBD5 Q9P267 Methyl-CpG-binding domain protein 5 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 254 1289 219 219 0
MCPH1 MCPH1 Q8NEM0 Microcephalin chr8 Not Cancer Driver No 1 hippie 110 446 62 62 1
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 540 3169 529 529 0
MLF2_ENST00000542154 MLF2 Q15773 Myeloid leukemia factor 2 chr12 Not Cancer Driver No 1 hippie, biogrid 37 187 32 32 0
MPDU1 MPDU1 O75352 Mannose-P-dolichol utilization defect 1 protein chr17 Not Cancer Driver No 1 hippie, biogrid 16 4 2 2 3
NKD2 NKD2 Q969F2 Protein naked cuticle homolog 2 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 64 451 64 64 0
NPPA NPPA P01160 Natriuretic peptides A chr1 Not Cancer Driver No 2 intact, hippie, biogrid 32 71 14 14 1
ODAPH_ENST00000311623 ODAPH Q17RF5 Odontogenesis associated phosphoprotein chr4 Not Cancer Driver No 1 intact, hippie 28 48 14 14 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 57 99 13 13 23
PITPNA PITPNA Q00169 Phosphatidylinositol transfer protein alpha isoform chr17 Not Cancer Driver No 1 intact, hippie, biogrid 26 82 7 7 0
PLBD1 PLBD1 Q6P4A8 Phospholipase B-like 1 chr12 Not Cancer Driver No 1 hippie, biogrid 71 21 2 2 0
PMVK PMVK Q15126 Phosphomevalonate kinase chr1 Not Cancer Driver No 1 biogrid 38 3 0 0 0
PSG11 PSG11 Q9UQ72 Pregnancy-specific beta-1-glycoprotein 11 chr19 Not Cancer Driver No 1 hippie, biogrid 115 34 9 9 0
RASGRF2 RASGRF2 O14827 Ras-specific guanine nucleotide-releasing factor 2 chr5 Not Cancer Driver No 1 hippie, biogrid 216 274 55 55 0
RDH12_ENST00000267502 RDH12 Q96NR8 Retinol dehydrogenase 12 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 41 0 0 0 10
RGS20 RGS20 O76081 Regulator of G-protein signaling 20 chr8 Not Cancer Driver No 1 hippie, biogrid 59 194 36 36 0
SARAF SARAF Q96BY9 Store-operated calcium entry-associated regulatory factor chr8 Not Cancer Driver No 1 hippie, biogrid 32 73 8 8 0
SCNM1 SCNM1 Q9BWG6 Sodium channel modifier 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 31 172 23 23 0
SDHA SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 1 intact, hippie, biogrid 115 71 13 13 7
SETD3 SETD3 Q86TU7 Actin-histidine N-methyltransferase chr14 Not Cancer Driver No 1 intact, hippie, biogrid 73 140 24 24 0
SLC25A32 SLC25A32 Q9H2D1 Mitochondrial folate transporter/carrier chr8 Not Cancer Driver No 3 hippie, biogrid 45 4 0 0 1
SLC25A35 SLC25A35 Q3KQZ1 Solute carrier family 25 member 35 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 26 3 1 1 0
SLC37A4_ENST00000545985 SLC37A4 O43826 Glucose-6-phosphate exchanger SLC37A4 chr11 Not Cancer Driver No 1 hippie, biogrid 41 17 1 1 32
SNRNP27 SNRNP27 Q8WVK2 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein chr2 Not Cancer Driver No 2 intact, hippie, biogrid 20 155 20 20 0
SSB SSB P05455 Lupus La protein chr2 Not Cancer Driver No 1 intact, hippie, biogrid 39 181 18 18 0
TBPL1 TBPL1 P62380 TATA box-binding protein-like 1 chr6 Not Cancer Driver No 1 hippie, biogrid 27 6 0 0 0
UBXN6 UBXN6 Q9BZV1 UBX domain-containing protein 6 chr19 Not Cancer Driver No 1 hippie, biogrid 64 132 26 26 0
UPK1A_ENST00000222275 UPK1A O00322 Uroplakin-1a chr19 Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
ZC3HC1 ZC3HC1 Q86WB0 Zinc finger C3HC-type protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 70 250 34 34 0
ZNF177_ENST00000589262 ZNF177 Q13360 Zinc finger protein 177 chr19 Not Cancer Driver No 1 intact, hippie 58 119 19 19 0