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PMF1_ENST00000368277 ,PMF1 ,Q6P1K2
  • Uniprot Accession= Q6P1K2
  • Ensembl Transcript= ENST00000368277.3
  • Uniprot Name= PMF1
  • Name= Polyamine-modulated factor 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 39
  • Number of Interaction partner in biogrid: 91
  • Number of Interaction partner in hippie: 103
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 Not Cancer Driver No 1 hippie, biogrid 130 615 66 66 0
ADNP2 ADNP2 Q6IQ32 Activity-dependent neuroprotector homeobox protein 2 chr18 Not Cancer Driver No 1 hippie, biogrid 133 475 53 53 0
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 Not Cancer Driver No 2 intact, hippie, biogrid 129 16 2 2 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 79 239 25 25 1
ATL3 ATL3 Q6DD88 Atlastin-3 chr11 Not Cancer Driver No 1 intact, hippie 43 57 5 5 1
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 biogrid 36 178 21 21 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 1 intact, hippie 98 861 79 79 0
BDP1 BDP1 A6H8Y1 Transcription factor TFIIIB component B'' homolog chr5 Not Cancer Driver No 1 biogrid 293 2495 276 276 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 115 546 73 73 10
BUB1 BUB1 O43683 Mitotic checkpoint serine/threonine-protein kinase BUB1 chr2 Not Cancer Driver No 1 hippie 139 466 64 64 0
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 Census Yes 1 hippie 96 480 35 35 7
CACTIN CACTIN Q8WUQ7 Cactin chr19 Not Cancer Driver No 1 biogrid 94 503 54 54 0
CATSPER1 CATSPER1 Q8NEC5 Cation channel sperm-associated protein 1 chr11 Not Cancer Driver No 1 intact, hippie 138 417 87 87 0
CBX1_ENST00000225603 CBX1 P83916 Chromobox protein homolog 1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 31 154 25 25 0
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 23 119 18 18 0
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 Not Cancer Driver No 4 intact, hippie, biogrid 21 116 12 12 0
CENPC CENPC Q03188 Centromere protein C chr4 Not Cancer Driver No 2 intact, hippie, biogrid 96 790 84 84 0
CENPK_ENST00000514814 CENPK Q9BS16 Centromere protein K chr5 Not Cancer Driver No 1 biogrid 28 91 8 8 0
CENPM CENPM Q9NSP4 Centromere protein M chr22 Not Cancer Driver No 1 biogrid 12 1 0 0 0
CENPW_ENST00000368328 CENPW Q5EE01 Centromere protein W chr6 Not Cancer Driver No 1 biogrid 9 5 1 1 0
CEP126 CEP126 Q9P2H0 Centrosomal protein of 126 kDa chr11 Not Cancer Driver No 1 intact, hippie 197 840 151 151 0
CEP89 CEP89 Q96ST8 Centrosomal protein of 89 kDa chr19 Census Yes 2 hippie, biogrid 96 540 72 72 0
CHAF1A CHAF1A Q13111 Chromatin assembly factor 1 subunit A chr19 Not Cancer Driver No 1 hippie, biogrid 133 767 99 99 0
CHAF1B CHAF1B Q13112 Chromatin assembly factor 1 subunit B chr21 Not Cancer Driver No 1 hippie, biogrid 65 186 30 30 0
CHAMP1 CHAMP1 Q96JM3 Chromosome alignment-maintaining phosphoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 85 624 65 65 0
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 hippie, biogrid 419 974 177 177 6
CMTM6 CMTM6 Q9NX76 CKLF-like MARVEL transmembrane domain-containing protein 6 chr3 Not Cancer Driver No 1 hippie, biogrid 10 30 0 0 0
COPS6 COPS6 Q7L5N1 COP9 signalosome complex subunit 6 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 38 30 6 6 0
COPS7A_ENST00000534947 COPS7A Q9UBW8 COP9 signalosome complex subunit 7a chr12 Not Cancer Driver No 1 hippie 32 74 10 10 0
COPS7B_ENST00000410024 COPS7B Q9H9Q2 COP9 signalosome complex subunit 7b chr2 Not Cancer Driver No 1 hippie 22 74 6 6 0
CRMP1_ENST00000397890 CRMP1 Q14194 Dihydropyrimidinase-related protein 1 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 122 96 15 15 0
CTNNBL1 CTNNBL1 Q8WYA6 Beta-catenin-like protein 1 chr20 Not Cancer Driver No 1 biogrid 72 158 24 24 0
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 Not Cancer Driver No 1 hippie 20 87 9 9 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie, biogrid 44 37 2 2 0
DONSON DONSON Q9NYP3 Protein downstream neighbor of Son chr21 Not Cancer Driver No 1 biogrid 50 217 13 13 6
DSN1 DSN1 Q9H410 Kinetochore-associated protein DSN1 homolog chr20 Not Cancer Driver No 7 intact, hippie, biogrid 45 191 28 28 0
DTNB DTNB O60941 Dystrobrevin beta chr2 Not Cancer Driver No 1 hippie, biogrid 75 337 42 42 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 Compendium Yes 1 hippie, biogrid 70 273 34 34 0
EFHC1 EFHC1 Q5JVL4 EF-hand domain-containing protein 1 chr6 Not Cancer Driver No 1 intact, hippie 79 78 15 15 17
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EHMT1 EHMT1 Q9H9B1 Histone-lysine N-methyltransferase EHMT1 chr9 Not Cancer Driver No 1 hippie, biogrid 182 701 97 97 1
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 Not Cancer Driver No 1 hippie, biogrid 142 585 71 71 0
EIF3H EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 Not Cancer Driver No 1 biogrid 37 109 12 12 0
EIF4G2_ENST00000640650 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 Not Cancer Driver No 1 biogrid 104 382 43 43 0
ENG ENG P17813 Endoglin chr9 Not Cancer Driver No 1 intact, hippie 60 114 15 15 32
FBXO28 FBXO28 Q9NVF7 F-box only protein 28 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 49 230 30 30 0
FBXO38_ENST00000340253 FBXO38 Q6PIJ6 F-box only protein 38 chr5 Not Cancer Driver No 1 hippie 133 440 48 48 1
GCC2 GCC2 Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 178 999 113 113 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 72 53 15 15 0
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 Not Cancer Driver No 1 hippie, biogrid 10 97 4 4 1
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 67 434 42 42 0
GNPAT GNPAT O15228 Dihydroxyacetone phosphate acyltransferase chr1 Not Cancer Driver No 1 hippie, biogrid 86 6 3 3 3
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 336 666 69 69 2
ING5_ENST00000313552 ING5 Q8WYH8 Inhibitor of growth protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 25 119 9 9 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie 67 291 28 28 3
KIF21B KIF21B O75037 Kinesin-like protein KIF21B chr1 Not Cancer Driver No 2 intact, hippie, biogrid 308 775 159 159 0
KLF11 KLF11 O14901 Krueppel-like factor 11 chr2 Not Cancer Driver No 1 hippie 57 308 38 38 2
KNL1 KNL1 Q8NG31 Kinetochore scaffold 1 chr15 Census Yes 2 intact, hippie 272 1265 135 135 1
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 biogrid 74 611 69 69 0
LRIF1 LRIF1 Q5T3J3 Ligand-dependent nuclear receptor-interacting factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 116 520 74 74 0
MED31 MED31 Q9Y3C7 Mediator of RNA polymerase II transcription subunit 31 chr17 Not Cancer Driver No 1 hippie, biogrid 16 15 1 1 0
MESD_ENST00000561312 MESD Q14696 LRP chaperone MESD chr15 Not Cancer Driver No 1 intact, hippie 21 150 14 14 0
METAP2 METAP2 P50579 Methionine aminopeptidase 2 chr12 Not Cancer Driver No 1 biogrid 54 176 19 19 0
MIS12 MIS12 Q9H081 Protein MIS12 homolog chr17 Not Cancer Driver No 9 intact, hippie, biogrid 14 15 2 2 0
MLF1_ENST00000355893 MLF1 P58340 Myeloid leukemia factor 1 chr3 Census Yes 1 hippie, biogrid 40 243 37 37 0
MLLT10_ENST00000377059 MLLT10 P55197 Protein AF-10 chr10 Census Yes 1 intact, hippie, biogrid 133 835 94 94 0
MRPL19_ENST00000409374 MRPL19 P49406 39S ribosomal protein L19, mitochondrial chr2 Not Cancer Driver No 1 biogrid 22 63 4 4 0
MRPL43_ENST00000318325 MRPL43 Q8N983 39S ribosomal protein L43, mitochondrial chr10 Not Cancer Driver No 1 biogrid 17 66 6 6 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 Not Cancer Driver No 2 hippie, biogrid 80 313 45 45 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 Census, Compendium Yes 2 intact, hippie 228 402 62 62 4
NFYC NFYC Q13952 Nuclear transcription factor Y subunit gamma chr1 Not Cancer Driver No 1 biogrid 46 320 32 32 0
NRBF2 NRBF2 Q96F24 Nuclear receptor-binding factor 2 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 34 224 25 25 0
NSL1 NSL1 Q96IY1 Kinetochore-associated protein NSL1 homolog chr1 Not Cancer Driver No 4 hippie, biogrid 30 117 12 12 0
NSMCE1 NSMCE1 Q8WV22 Non-structural maintenance of chromosomes element 1 homolog chr16 Not Cancer Driver No 3 intact, hippie, biogrid 40 31 8 8 0
NUF2_ENST00000367900 NUF2 Q9BZD4 Kinetochore protein Nuf2 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 97 74 20 20 0
NUP58 NUP58 Q9BVL2 Nucleoporin p58/p45 chr13 Not Cancer Driver No 1 intact, hippie 76 377 49 49 0
PANK2 PANK2 Q9BZ23 Pantothenate kinase 2, mitochondrial chr20 Not Cancer Driver No 1 intact, hippie 46 206 14 14 30
PCGF6 PCGF6 Q9BYE7 Polycomb group RING finger protein 6 chr10 Not Cancer Driver No 1 hippie, biogrid 29 142 11 11 0
PGRMC2_ENST00000296425 PGRMC2 O15173 Membrane-associated progesterone receptor component 2 chr4 Not Cancer Driver No 1 hippie, biogrid 16 83 4 4 0
PMF1-BGLAP_ENST00000320139 PMF1-BGLAP Q6P1K2-3 Isoform 3 of Polyamine-modulated factor 1 chr1 Not Cancer Driver No 1 biogrid 12 70 0 0 0
PMF1_ENST00000368277 PMF1 Q6P1K2 Polyamine-modulated factor 1 chr1 Not Cancer Driver No 1 biogrid 20 76 6 6 0
POGZ POGZ Q7Z3K3 Pogo transposable element with ZNF domain chr1 Not Cancer Driver No 1 hippie, biogrid 157 746 78 78 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 3 hippie, biogrid 26 23 4 4 0
PPP1R21 PPP1R21 Q6ZMI0 Protein phosphatase 1 regulatory subunit 21 chr2 Not Cancer Driver No 1 hippie, biogrid 86 315 33 33 0
PTN PTN P21246 Pleiotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 43 51 11 11 0
RGPD8 RGPD8 O14715 RANBP2-like and GRIP domain-containing protein 8 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 129 621 71 71 0
RPS19BP1 RPS19BP1 Q86WX3 Active regulator of SIRT1 chr22 Not Cancer Driver No 1 hippie, biogrid 5 112 5 5 0
RUFY1 RUFY1 Q96T51 RUN and FYVE domain-containing protein 1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 79 356 40 40 0
RUFY2_ENST00000602465 RUFY2 Q8WXA3 RUN and FYVE domain-containing protein 2 chr10 Not Cancer Driver No 2 hippie, biogrid 72 182 24 24 0
S100P S100P P25815 Protein S100-P chr4 Not Cancer Driver No 1 hippie, biogrid 7 3 1 1 0
SCAI_ENST00000336505 SCAI Q8N9R8 Protein SCAI chr9 Not Cancer Driver No 1 hippie, biogrid 95 117 13 13 0
SEC63 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 98 266 37 37 0
SGO1 SGO1 Q5FBB7 Shugoshin 1 chr3 Not Cancer Driver No 1 hippie 57 360 39 39 1
SGTB SGTB Q96EQ0 Small glutamine-rich tetratricopeptide repeat-containing protein beta chr5 Not Cancer Driver No 1 hippie, biogrid 28 114 10 10 0
SHC3 SHC3 Q92529 SHC-transforming protein 3 chr9 Not Cancer Driver No 1 hippie 94 432 64 64 0
SNAPC1 SNAPC1 Q16533 snRNA-activating protein complex subunit 1 chr14 Not Cancer Driver No 1 biogrid 36 158 16 16 0
SPC24 SPC24 Q8NBT2 Kinetochore protein Spc24 chr19 Not Cancer Driver No 2 hippie, biogrid 9 88 5 5 0
SPC25 SPC25 Q9HBM1 Kinetochore protein Spc25 chr2 Not Cancer Driver No 3 hippie, biogrid 15 34 2 2 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 intact, hippie 71 194 35 35 2
STRN STRN O43815 Striatin chr2 Census, Compendium Yes 1 hippie, biogrid 97 348 43 43 0
STRN3 STRN3 Q13033 Striatin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 93 366 42 42 0
STXBP4 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 78 211 24 24 0
SUGT1 SUGT1 Q9Y2Z0 Protein SGT1 homolog chr13 Not Cancer Driver No 1 hippie 31 119 5 5 0
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 Not Cancer Driver No 1 biogrid 129 241 34 34 1
TALDO1 TALDO1 P37837 Transaldolase chr11 Not Cancer Driver No 2 intact, hippie, biogrid 51 31 4 4 0
TBC1D21 TBC1D21 Q8IYX1 TBC1 domain family member 21 chr15 Not Cancer Driver No 1 hippie 62 7 0 0 0
TCP10L TCP10L Q8TDR4 T-complex protein 10A homolog 1 chr21 Not Cancer Driver No 1 intact, hippie 32 213 32 32 0
TPST2 TPST2 O60704 Protein-tyrosine sulfotransferase 2 chr22 Not Cancer Driver No 1 hippie, biogrid 47 48 6 6 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TSNAX TSNAX Q99598 Translin-associated protein X chr1 Not Cancer Driver No 2 hippie, biogrid 23 68 3 3 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 Not Cancer Driver No 1 hippie 25 102 12 12 0
USHBP1 USHBP1 Q8N6Y0 Usher syndrome type-1C protein-binding protein 1 chr19 Not Cancer Driver No 1 intact, hippie 118 583 95 95 0
WDR45B WDR45B Q5MNZ6 WD repeat domain phosphoinositide-interacting protein 3 chr17 Not Cancer Driver No 1 hippie, biogrid 48 8 1 1 0
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 Not Cancer Driver No 1 biogrid 25 7 1 1 0
WIZ_ENST00000263381 WIZ O95785-2 Isoform 2 of Protein Wiz chr19 Not Cancer Driver No 1 hippie, biogrid 148 651 135 135 0
YBEY_ENST00000397691 YBEY P58557 Endoribonuclease YbeY chr21 Not Cancer Driver No 1 hippie, biogrid 19 9 2 2 0
ZC4H2 ZC4H2 Q9NQZ6 Zinc finger C4H2 domain-containing protein chrX Not Cancer Driver No 2 intact, hippie, biogrid 60 136 43 43 13
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 67 23 0 0 3
ZNF644_ENST00000370440 ZNF644 Q9H582 Zinc finger protein 644 chr1 Not Cancer Driver No 1 hippie, biogrid 176 870 108 108 4
ZRANB1 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 Not Cancer Driver No 1 hippie, biogrid 87 158 25 25 0
ZWINT ZWINT O95229 ZW10 interactor chr10 Not Cancer Driver No 6 hippie, biogrid 65 168 44 44 0