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PLK3 ,PLK3 ,Q9H4B4
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 11
  • Number of Interaction partner in hippie: 40
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AIP AIP O00170 AH receptor-interacting protein chr11 Not Cancer Driver No 1 hippie, biogrid 32 64 9 9 1
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 hippie 36 178 21 21 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 Not Cancer Driver No 1 hippie 29 55 3 3 0
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 Census Yes 1 hippie 96 480 35 35 7
CDC25C CDC25C P30307 M-phase inducer phosphatase 3 chr5 Not Cancer Driver No 1 hippie 61 224 26 26 0
CENPU CENPU Q71F23 Centromere protein U chr4 Not Cancer Driver No 1 hippie 51 298 42 42 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 1 hippie 335 157 130 130 13
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 Not Cancer Driver No 1 hippie 24 6 1 1 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie, biogrid 44 37 2 2 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 118 435 51 51 0
LARP1 LARP1 Q6PKG0-3 Isoform 2 of La-related protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 136 726 100 100 0
LARP4_ENST00000398473 LARP4 Q71RC2 La-related protein 4 chr12 Not Cancer Driver No 1 hippie, biogrid 86 486 53 53 0
LSM5 LSM5 Q9Y4Y9 U6 snRNA-associated Sm-like protein LSm5 chr7 Not Cancer Driver No 1 hippie 7 15 0 0 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 Census, Compendium Yes 1 hippie 94 96 24 24 6
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 62 2 0 0 7
MFF MFF Q9GZY8 Mitochondrial fission factor chr2 Not Cancer Driver No 1 hippie 59 264 47 47 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 hippie, biogrid 540 3169 529 529 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie, biogrid 110 101 8 8 0
MRTO4 MRTO4 Q9UKD2 mRNA turnover protein 4 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 23 73 5 5 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
POU2F1_ENST00000541643 POU2F1 P14859 POU domain, class 2, transcription factor 1 chr1 Not Cancer Driver No 1 hippie 95 433 50 50 0
PPM1A_ENST00000395076 PPM1A P35813 Protein phosphatase 1A chr14 Not Cancer Driver No 1 hippie 60 134 24 24 0
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 Census, Compendium Yes 1 hippie 315 462 107 107 0
PURA PURA Q00577 Transcriptional activator protein Pur-alpha chr5 Not Cancer Driver No 1 hippie, biogrid 22 188 10 10 6
RAD52 RAD52 P43351 DNA repair protein RAD52 homolog chr12 Not Cancer Driver No 1 hippie 41 251 30 30 0
RNF141 RNF141 Q8WVD5 RING finger protein 141 chr11 Not Cancer Driver No 1 hippie 28 48 4 4 0
RRM2_ENST00000641198 RRM2 P31350 Ribonucleoside-diphosphate reductase subunit M2 chr2 Not Cancer Driver No 1 hippie 40 48 0 0 0
SIAH2 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 Not Cancer Driver No 1 hippie 48 68 3 3 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 Not Cancer Driver No 1 hippie 271 1573 232 232 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 1 hippie 21 107 13 13 5
SNCB_ENST00000510387 SNCB Q16143 Beta-synuclein chr5 Not Cancer Driver No 1 hippie 23 110 21 21 0
SRPK1 SRPK1 Q96SB4 SRSF protein kinase 1 chr6 Not Cancer Driver No 1 hippie, biogrid 73 329 32 32 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
TNS2_ENST00000314250 TNS2 Q63HR2 Tensin-2 chr12 Not Cancer Driver No 1 hippie 132 799 63 63 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 Compendium Yes 1 hippie, biogrid 150 508 59 59 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRIP13 TRIP13 Q15645 Pachytene checkpoint protein 2 homolog chr5 Not Cancer Driver No 1 hippie 62 30 6 6 1
TRMT61A TRMT61A Q96FX7 tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A chr14 Not Cancer Driver No 1 hippie, biogrid 16 74 9 9 0
VRK1 VRK1 Q99986 Serine/threonine-protein kinase VRK1 chr14 Not Cancer Driver No 1 hippie 52 80 9 9 0