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PLEKHO1 ,PLEKHO1 ,Q53GL0
  • Uniprot Accession= Q53GL0
  • Ensembl Transcript= ENST00000369124.4
  • Uniprot Name= PLEKHO1
  • Name= Pleckstrin homology domain-containing family O member 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 40
  • Number of Interaction partner in hippie: 76
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADAM33 ADAM33 Q9BZ11 Disintegrin and metalloproteinase domain-containing protein 33 chr20 Not Cancer Driver No 1 hippie 94 165 28 28 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 Census Yes 1 hippie 77 84 9 9 2
AKT3_ENST00000366539 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 Census, Compendium Yes 1 hippie 92 131 24 24 3
AMY1A AMY1A P0DUB6 Alpha-amylase 1A chr1 Not Cancer Driver No 1 hippie 20 29 0 0 0
AMY1C AMY1C P0DTE8 Alpha-amylase 1C chr1 Not Cancer Driver No 1 biogrid 37 29 2 2 0
BNIP2_ENST00000607373 BNIP2 Q12982 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 chr15 Not Cancer Driver No 1 hippie 28 144 18 18 0
BRICD5_ENST00000562360 BRICD5 Q6PL45 BRICHOS domain-containing protein 5 chr16 Not Cancer Driver No 1 hippie 43 82 11 11 0
C4orf3_ENST00000504110 C4orf3 Q8WVX3 Uncharacterized protein C4orf3 chr4 Not Cancer Driver No 1 hippie 11 18 5 5 0
CAPZA1 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 40 41 2 2 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 3 hippie, biogrid 37 19 0 0 0
CAPZB_ENST00000375142 CAPZB P47756 F-actin-capping protein subunit beta chr1 Not Cancer Driver No 2 hippie, biogrid 33 66 3 3 0
CENPV CENPV Q7Z7K6 Centromere protein V chr17 Not Cancer Driver No 2 hippie, biogrid 16 154 2 2 0
CEP19 CEP19 Q96LK0 Centrosomal protein of 19 kDa chr3 Not Cancer Driver No 1 hippie 30 71 11 11 0
COL8A2_ENST00000303143 COL8A2 P25067 Collagen alpha-2(VIII) chain chr1 Not Cancer Driver No 1 hippie 75 559 58 58 4
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 hippie 71 75 8 8 4
CYP4F2 CYP4F2 P78329 Cytochrome P450 4F2 chr19 Not Cancer Driver No 1 hippie 136 17 3 3 0
DDX31_ENST00000372153 DDX31 Q9H8H2 Probable ATP-dependent RNA helicase DDX31 chr9 Not Cancer Driver No 2 hippie, biogrid 99 342 38 38 0
DDX51 DDX51 Q8N8A6 ATP-dependent RNA helicase DDX51 chr12 Not Cancer Driver No 2 hippie, biogrid 51 244 8 8 0
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 1 hippie 35 196 26 26 0
DOK2 DOK2 O60496 Docking protein 2 chr8 Not Cancer Driver No 2 hippie, biogrid 58 254 31 31 0
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 Not Cancer Driver No 1 hippie 362 1183 170 170 19
FLNC FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 2 hippie, biogrid 546 1442 288 288 7
FTSJ3 FTSJ3 Q8IY81 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 chr17 Not Cancer Driver No 2 hippie, biogrid 103 533 66 66 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 2 hippie, biogrid 88 312 53 53 0
GLYR1 GLYR1 Q49A26 Putative oxidoreductase GLYR1 chr16 Not Cancer Driver No 1 hippie, biogrid 87 201 27 27 0
GNAO1_ENST00000638705 GNAO1 P09471 Guanine nucleotide-binding protein G(o) subunit alpha chr16 Not Cancer Driver No 1 hippie 54 10 0 0 15
GTPBP10 GTPBP10 A4D1E9 GTP-binding protein 10 chr7 Not Cancer Driver No 2 hippie, biogrid 50 52 4 4 0
GTPBP2 GTPBP2 Q9BX10 GTP-binding protein 2 chr6 Not Cancer Driver No 2 hippie, biogrid 53 89 5 5 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie, biogrid 107 16 4 4 18
IFI35_ENST00000415816 IFI35 P80217 Interferon-induced 35 kDa protein chr17 Not Cancer Driver No 1 hippie 33 63 10 10 0
KBTBD7 KBTBD7 Q8WVZ9 Kelch repeat and BTB domain-containing protein 7 chr13 Not Cancer Driver No 1 hippie, biogrid 92 105 6 6 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie, biogrid 788 7 2 2 27
LRP10 LRP10 Q7Z4F1 Low-density lipoprotein receptor-related protein 10 chr14 Not Cancer Driver No 1 hippie 99 237 32 32 0
MMD MMD Q15546 Monocyte to macrophage differentiation factor chr17 Not Cancer Driver No 1 hippie 30 0 0 0 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 Not Cancer Driver No 1 hippie, biogrid 144 463 47 47 0
NAPB_ENST00000377026 NAPB Q9H115 Beta-soluble NSF attachment protein chr20 Not Cancer Driver No 1 hippie 30 29 2 2 0
NLE1 NLE1 Q9NVX2 Notchless protein homolog 1 chr17 Not Cancer Driver No 2 hippie, biogrid 60 21 3 3 0
NMNAT1 NMNAT1 Q9HAN9 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 chr1 Not Cancer Driver No 2 hippie, biogrid 39 49 7 7 28
NOC2L NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 Not Cancer Driver No 2 hippie, biogrid 77 281 31 31 0
NOC3L NOC3L Q8WTT2 Nucleolar complex protein 3 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 75 281 29 29 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 Not Cancer Driver No 2 hippie, biogrid 90 267 31 31 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
PDCD11 PDCD11 Q14690 Protein RRP5 homolog chr10 Not Cancer Driver No 2 hippie, biogrid 212 487 64 64 0
PDIA6_ENST00000272227 PDIA6 Q15084 Protein disulfide-isomerase A6 chr2 Not Cancer Driver No 1 hippie 55 82 11 11 0
PLEKHO1 PLEKHO1 Q53GL0 Pleckstrin homology domain-containing family O member 1 chr1 Not Cancer Driver No 1 hippie 55 341 46 46 0
PPAN PPAN Q9NQ55 Suppressor of SWI4 1 homolog chr19 Not Cancer Driver No 1 hippie 65 257 42 42 0
PPAN-P2RY11_ENST00000428358 PPAN-P2RY11 Q9NQ55-3 Isoform 3 of Suppressor of SWI4 1 homolog chr19 Not Cancer Driver No 1 biogrid 81 275 52 52 0
PSMC5 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 Not Cancer Driver No 1 hippie 52 64 6 6 0
RBM28 RBM28 Q9NW13 RNA-binding protein 28 chr7 Not Cancer Driver No 1 hippie, biogrid 97 512 66 66 1
RPL26L1 RPL26L1 Q9UNX3 60S ribosomal protein L26-like 1 chr5 Not Cancer Driver No 2 hippie, biogrid 21 107 11 11 0
RPL3 RPL3 P39023 60S ribosomal protein L3 chr22 Not Cancer Driver No 1 hippie, biogrid 34 79 3 3 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 Census Yes 1 hippie, biogrid 57 96 17 17 2
RPS20_ENST00000521262 RPS20 P60866 40S ribosomal protein S20 chr8 Not Cancer Driver No 1 hippie 18 53 8 8 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SDAD1 SDAD1 Q9NVU7 Protein SDA1 homolog chr4 Not Cancer Driver No 1 hippie, biogrid 65 288 29 29 0
SEC24D SEC24D O94855 Protein transport protein Sec24D chr4 Not Cancer Driver No 2 hippie, biogrid 130 319 45 45 2
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 Not Cancer Driver No 1 hippie 44 172 11 11 0
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 Not Cancer Driver No 1 hippie 89 256 31 31 0
SPTY2D1 SPTY2D1 Q68D10 Protein SPT2 homolog chr11 Not Cancer Driver No 2 hippie, biogrid 94 670 89 89 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie, biogrid 77 456 63 63 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie, biogrid 165 572 87 87 0
THSD7B THSD7B Q9C0I4 Thrombospondin type-1 domain-containing protein 7B chr2 Not Cancer Driver No 1 hippie 652 94 19 19 0
TMEM218 TMEM218 A2RU14 Transmembrane protein 218 chr11 Not Cancer Driver No 1 hippie 14 0 0 0 0
TNF TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 1 hippie 24 45 3 3 0
TRAF3IP3 TRAF3IP3 Q9Y228 TRAF3-interacting JNK-activating modulator chr1 Not Cancer Driver No 1 hippie 90 347 63 63 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 67 62 7 7 0
TRAM1L1 TRAM1L1 Q8N609 Translocating chain-associated membrane protein 1-like 1 chr4 Not Cancer Driver No 1 hippie 71 40 14 14 0
TRMT1L TRMT1L Q7Z2T5 TRMT1-like protein chr1 Not Cancer Driver No 2 hippie, biogrid 71 241 19 19 0
TSPAN33 TSPAN33 Q86UF1 Tetraspanin-33 chr7 Not Cancer Driver No 1 hippie 26 0 0 0 0
TSPO2 TSPO2 Q5TGU0 Translocator protein 2 chr6 Not Cancer Driver No 1 hippie 23 7 3 3 0
UBA6 UBA6 A0AVT1 Ubiquitin-like modifier-activating enzyme 6 chr4 Not Cancer Driver No 2 hippie, biogrid 133 90 10 10 0
URB1 URB1 O60287 Nucleolar pre-ribosomal-associated protein 1 chr21 Not Cancer Driver No 2 hippie, biogrid 93 180 2 2 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 2 hippie, biogrid 170 215 45 45 0
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 Not Cancer Driver No 1 hippie 11 17 1 1 0
WDR45B WDR45B Q5MNZ6 WD repeat domain phosphoinositide-interacting protein 3 chr17 Not Cancer Driver No 2 hippie, biogrid 48 8 1 1 0
ZFPL1 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie 40 127 16 16 0