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PLEKHN1 ,PLEKHN1 ,Q494U1
  • Uniprot Accession= Q494U1
  • Ensembl Transcript= ENST00000379410.7
  • Uniprot Name= PLEKHN1
  • Name= Pleckstrin homology domain-containing family N member 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 36
  • Number of Interaction partner in biogrid: 9
  • Number of Interaction partner in hippie: 61
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 intact, hippie 56 361 38 38 0
AKAP8L AKAP8L Q9ULX6 A-kinase anchor protein 8-like chr19 Not Cancer Driver No 1 intact, hippie 76 510 61 61 0
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 Not Cancer Driver No 1 hippie 64 373 42 42 0
ATXN1 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 2 intact, hippie 193 604 168 168 0
BIRC8 BIRC8 Q96P09 Baculoviral IAP repeat-containing protein 8 chr19 Not Cancer Driver No 1 intact, hippie 79 39 10 10 0
BRWD3 BRWD3 Q6RI45 Bromodomain and WD repeat-containing protein 3 chrX Not Cancer Driver No 1 hippie 369 867 174 174 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 42 212 19 19 0
CYSRT1 CYSRT1 B8A4K4 Cysteine-rich tail protein 1 chr9 Not Cancer Driver No 1 intact, hippie 9 142 5 5 0
ELP1 ELP1 O95163 Elongator complex protein 1 chr9 Not Cancer Driver No 1 hippie 143 157 23 23 2
ELP2_ENST00000358232 ELP2 Q6IA86 Elongator complex protein 2 chr18 Not Cancer Driver No 1 hippie, biogrid 65 16 2 2 0
ELP3 ELP3 Q9H9T3 Elongator complex protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 60 19 4 4 0
FHL5 FHL5 Q5TD97 Four and a half LIM domains protein 5 chr6 Not Cancer Driver No 1 hippie 106 0 0 0 0
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 Not Cancer Driver No 1 hippie 90 262 68 68 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 intact, hippie 6 301 6 6 22
KLHL42 KLHL42 Q9P2K6 Kelch-like protein 42 chr12 Not Cancer Driver No 1 hippie, biogrid 48 57 4 4 0
KRT31 KRT31 Q15323 Keratin, type I cuticular Ha1 chr17 Not Cancer Driver No 1 hippie 116 64 16 16 0
KRT36 KRT36 O76013 Keratin, type I cuticular Ha6 chr17 Not Cancer Driver No 1 intact, hippie 99 52 18 18 0
KRT83 KRT83 P78385 Keratin, type II cuticular Hb3 chr12 Not Cancer Driver No 1 intact, hippie 88 22 3 3 2
KRTAP1-3 KRTAP1-3 Q8IUG1 Keratin-associated protein 1-3 chr17 Not Cancer Driver No 1 intact, hippie 31 0 0 0 0
KRTAP19-6 KRTAP19-6 Q3LI70 Keratin-associated protein 19-6 chr21 Not Cancer Driver No 1 intact, hippie 15 0 0 0 0
KRTAP6-2 KRTAP6-2 Q3LI66 Keratin-associated protein 6-2 chr21 Not Cancer Driver No 1 intact, hippie 31 0 0 0 0
LPXN_ENST00000395074 LPXN O60711 Leupaxin chr11 Not Cancer Driver No 2 intact, hippie 43 134 16 16 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie 78 508 66 66 0
MTUS2 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 1 intact, hippie 370 1208 329 329 0
NAA60_ENST00000572584 NAA60 Q9H7X0 N-alpha-acetyltransferase 60 chr16 Not Cancer Driver No 1 intact, hippie 33 0 0 0 0
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 Not Cancer Driver No 1 intact, hippie 47 124 20 20 0
NOTCH2NLA NOTCH2NLA Q7Z3S9 Notch homolog 2 N-terminal-like protein A chr1 Not Cancer Driver No 1 hippie 68 17 2 2 0
OPALIN OPALIN Q96PE5 Opalin chr10 Not Cancer Driver No 1 hippie, biogrid 29 86 18 18 0
PAK5 PAK5 Q9P286 Serine/threonine-protein kinase PAK 5 chr20 Not Cancer Driver No 1 intact, hippie 226 407 123 123 0
PDLIM7 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 Not Cancer Driver No 1 hippie 48 244 20 20 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 intact, hippie 30 157 13 13 0
PPM1J PPM1J Q5JR12 Protein phosphatase 1J chr1 Not Cancer Driver No 1 intact, hippie 51 206 16 16 0
PPP1R16B PPP1R16B Q96T49 Protein phosphatase 1 regulatory inhibitor subunit 16B chr20 Not Cancer Driver No 1 intact, hippie 132 220 66 66 0
PPP1R32 PPP1R32 Q7Z5V6 Protein phosphatase 1 regulatory subunit 32 chr11 Not Cancer Driver No 1 intact, hippie 70 379 55 55 0
PRICKLE4_ENST00000394260 PRICKLE4 Q2TBC4 Prickle-like protein 4 chr6 Not Cancer Driver No 1 hippie 44 130 15 15 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 Not Cancer Driver No 1 intact, hippie 128 98 26 26 0
PSMB5 PSMB5 P28074 Proteasome subunit beta type-5 chr14 Not Cancer Driver No 1 intact, hippie 39 9 0 0 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 2 intact, hippie, biogrid 62 341 24 24 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie 25 25 2 2 0
REL REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 3 intact, hippie 68 363 43 43 0
RFX6 RFX6 Q8HWS3 DNA-binding protein RFX6 chr6 Not Cancer Driver No 1 intact, hippie 239 422 94 94 3
RNF216_ENST00000425013 RNF216 Q9NWF9 E3 ubiquitin-protein ligase RNF216 chr7 Not Cancer Driver No 1 hippie 108 415 57 57 2
SORBS3 SORBS3 O60504 Vinexin chr8 Not Cancer Driver No 1 hippie 62 577 56 56 0
SSC4D SSC4D Q8WTU2 Scavenger receptor cysteine-rich domain-containing group B protein chr7 Not Cancer Driver No 1 hippie 58 90 7 7 0
TAOK1 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 Not Cancer Driver No 1 hippie, biogrid 116 601 59 59 0
TAX1BP1 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 Not Cancer Driver No 1 hippie 78 429 50 50 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 141 662 136 136 13
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 Compendium Yes 1 intact, hippie 68 102 6 6 5
TP53BP2 TP53BP2 Q13625 Apoptosis-stimulating of p53 protein 2 chr1 Not Cancer Driver No 2 intact, hippie 152 868 118 118 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 3 intact, hippie 51 63 9 9 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 intact, hippie 59 87 11 11 0
TRIP6 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 Not Cancer Driver No 1 intact, hippie 62 268 19 19 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 Not Cancer Driver No 1 hippie, biogrid 20 102 8 8 0
USP54 USP54 Q70EL1 Inactive ubiquitin carboxyl-terminal hydrolase 54 chr10 Not Cancer Driver No 1 intact, hippie 186 1268 143 143 0
WDR45B WDR45B Q5MNZ6 WD repeat domain phosphoinositide-interacting protein 3 chr17 Not Cancer Driver No 1 hippie, biogrid 48 8 1 1 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 intact, hippie 79 108 9 9 3
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX Not Cancer Driver No 1 hippie 89 55 6 6 0
ZC4H2 ZC4H2 Q9NQZ6 Zinc finger C4H2 domain-containing protein chrX Not Cancer Driver No 1 intact, hippie 60 136 43 43 13
ZNF438 ZNF438 Q7Z4V0 Zinc finger protein 438 chr10 Not Cancer Driver No 1 intact, hippie 123 612 90 90 0
ZRANB1 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 Not Cancer Driver No 1 hippie 87 158 25 25 0