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PKLR ,PKLR ,P30613
  • Uniprot Accession= P30613
  • Ensembl Transcript= ENST00000342741.5
  • Uniprot Name= PKLR
  • Name= Pyruvate kinase PKLR
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 30
  • Number of Interaction partner in hippie: 45
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 Not Cancer Driver No 1 hippie 59 61 12 12 0
ARHGEF6 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX Not Cancer Driver No 1 hippie 158 223 45 45 0
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 Census, Compendium Yes 1 biogrid 457 1542 225 225 46
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 Census Yes 1 hippie, biogrid 96 480 35 35 7
CLEC4G CLEC4G Q6UXB4 C-type lectin domain family 4 member G chr19 Not Cancer Driver No 1 hippie 40 35 4 4 0
CPNE7 CPNE7 Q9UBL6 Copine-7 chr16 Not Cancer Driver No 1 hippie 71 50 6 6 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 1 biogrid 41 18 1 1 0
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
CYP4B1_ENST00000271153 CYP4B1 P13584 Cytochrome P450 4B1 chr1 Not Cancer Driver No 1 hippie, biogrid 124 8 2 2 0
DKK2 DKK2 Q9UBU2 Dickkopf-related protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 108 70 22 22 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 Not Cancer Driver No 1 hippie 96 514 64 64 0
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 Not Cancer Driver No 1 hippie, biogrid 74 121 17 17 3
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 biogrid 171 187 39 39 3
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 Not Cancer Driver No 1 biogrid 186 119 17 17 7
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
FCER1A FCER1A P12319 High affinity immunoglobulin epsilon receptor subunit alpha chr1 Not Cancer Driver No 1 hippie, biogrid 83 13 4 4 0
ISX_ENST00000404699 ISX Q2M1V0 Intestine-specific homeobox chr22 Census Yes 1 hippie, biogrid 64 102 32 32 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
LRRC3B_ENST00000417744 LRRC3B Q96PB8 Leucine-rich repeat-containing protein 3B chr3 Not Cancer Driver No 1 hippie, biogrid 83 25 6 6 0
MAPK12 MAPK12 P53778 Mitogen-activated protein kinase 12 chr22 Not Cancer Driver No 1 biogrid 31 63 5 5 0
MRAS_ENST00000423968 MRAS O14807 Ras-related protein M-Ras chr3 Not Cancer Driver No 1 hippie, biogrid 27 50 13 13 3
MYOC MYOC Q99972 Myocilin chr1 Not Cancer Driver No 1 hippie 92 196 43 43 58
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NT5DC1 NT5DC1 Q5TFE4 5'-nucleotidase domain-containing protein 1 chr6 Not Cancer Driver No 2 hippie, biogrid 44 58 5 5 0
ODF3 ODF3 Q96PU9 Outer dense fiber protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 22 174 14 14 0
OTUD5 OTUD5 Q96G74 OTU domain-containing protein 5 chrX Not Cancer Driver No 1 hippie, biogrid 55 430 39 39 4
PAICS_ENST00000512576 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 Not Cancer Driver No 1 hippie, biogrid 23 35 3 3 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 hippie 57 299 30 30 2
PCGF3 PCGF3 Q3KNV8 Polycomb group RING finger protein 3 chr4 Not Cancer Driver No 1 hippie, biogrid 38 47 11 11 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 30 22 3 3 1
PI15 PI15 O43692 Peptidase inhibitor 15 chr8 Not Cancer Driver No 1 hippie, biogrid 87 4 1 1 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie, biogrid 78 58 13 13 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie 62 341 24 24 0
RASL11A RASL11A Q6T310 Ras-like protein family member 11A chr13 Not Cancer Driver No 1 hippie, biogrid 31 40 6 6 0
RFXANK_ENST00000407360 RFXANK O14593 DNA-binding protein RFXANK chr19 Not Cancer Driver No 1 hippie, biogrid 22 120 6 6 1
SAV1 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 Not Cancer Driver No 1 hippie 42 243 17 17 0
SBDS SBDS Q9Y3A5 Ribosome maturation protein SBDS chr7 Census Yes 1 hippie, biogrid 28 12 1 1 2
SPIN4 SPIN4 Q56A73 Spindlin-4 chrX Not Cancer Driver No 1 hippie, biogrid 35 63 9 9 0
SRD5A2 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 Not Cancer Driver No 1 hippie, biogrid 48 0 0 0 21
SRPK3 SRPK3 Q9UPE1 SRSF protein kinase 3 chrX Not Cancer Driver No 1 hippie, biogrid 63 217 30 30 0
SUMO4 SUMO4 Q6EEV6 Small ubiquitin-related modifier 4 chr6 Not Cancer Driver No 1 hippie 7 69 4 4 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
TMEM69 TMEM69 Q5SWH9 Transmembrane protein 69 chr1 Not Cancer Driver No 1 hippie, biogrid 19 4 0 0 0
UBE2J2_ENST00000349431 UBE2J2 Q8N2K1 Ubiquitin-conjugating enzyme E2 J2 chr1 Not Cancer Driver No 1 hippie, biogrid 42 51 7 7 0
USP3 USP3 Q9Y6I4 Ubiquitin carboxyl-terminal hydrolase 3 chr15 Not Cancer Driver No 1 hippie, biogrid 60 45 4 4 0
USPL1 USPL1 Q5W0Q7 SUMO-specific isopeptidase USPL1 chr13 Not Cancer Driver No 1 hippie, biogrid 107 578 55 55 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0