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PKD1 ,PKD1 ,P98161
  • Uniprot Accession= P98161
  • Ensembl Transcript= ENST00000262304.8
  • Uniprot Name= PKD1
  • Name= Polycystin-1
  • Chromosome= chr16
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 5
  • Number of Interaction partner in biogrid: 1
  • Number of Interaction partner in hippie: 48
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
ACTN1_ENST00000193403 ACTN1 P12814 Alpha-actinin-1 chr14 Not Cancer Driver No 1 hippie 108 195 30 30 6
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
ATF7IP_ENST00000540793 ATF7IP Q6VMQ6 Activating transcription factor 7-interacting protein 1 chr12 Compendium Yes 1 intact, hippie 160 1136 139 139 0
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 hippie 115 115 16 16 6
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
C1orf54 C1orf54 Q8WWF1 Uncharacterized protein C1orf54 chr1 Not Cancer Driver No 1 hippie, biogrid 17 28 3 3 0
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 hippie 287 145 18 18 151
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 Census, Compendium Yes 1 hippie 247 1212 214 214 148
COL2A1 COL2A1 P02458 Collagen alpha-1(II) chain chr12 Census Yes 1 hippie 258 1215 207 207 64
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 1 hippie 126 268 35 35 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DES DES P17661 Desmin chr2 Not Cancer Driver No 1 hippie 71 264 41 41 35
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GAN GAN Q9H2C0 Gigaxonin chr16 Not Cancer Driver No 1 hippie 74 33 6 6 19
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 Not Cancer Driver No 1 hippie 286 631 178 178 0
JADE1_ENST00000512960 JADE1 Q6IE81 Protein Jade-1 chr4 Not Cancer Driver No 1 hippie 94 409 47 47 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 1 hippie 136 59 5 5 5
JUP JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 hippie 112 241 37 37 0
KRT18_ENST00000388837 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 Not Cancer Driver No 1 hippie 57 179 21 21 4
KRT8_ENST00000546897 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie 65 221 37 37 3
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LTB4R2 LTB4R2 Q9NPC1 Leukotriene B4 receptor 2 chr14 Not Cancer Driver No 1 intact, hippie 29 55 11 11 0
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 1 hippie 124 445 70 70 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 Not Cancer Driver No 1 hippie 37 181 12 12 1
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 Not Cancer Driver No 1 hippie 89 88 19 19 0
NPHP1_ENST00000393272 NPHP1 O15259 Nephrocystin-1 chr2 Not Cancer Driver No 1 hippie 108 259 32 32 1
NUDCD2 NUDCD2 Q8WVJ2 NudC domain-containing protein 2 chr5 Not Cancer Driver No 1 hippie 12 39 6 6 0
PIP5K1C_ENST00000335312 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 Not Cancer Driver No 1 hippie 98 360 60 60 1
PKD1 PKD1 P98161 Polycystin-1 chr16 Not Cancer Driver No 1 hippie 393 690 66 66 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 Not Cancer Driver No 2 intact, hippie 113 375 35 35 10
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 intact, hippie 70 116 11 11 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 Not Cancer Driver No 1 hippie 134 425 55 55 0
PTPRG PTPRG P23470 Receptor-type tyrosine-protein phosphatase gamma chr3 Not Cancer Driver No 1 hippie 212 465 61 61 0
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 Not Cancer Driver No 1 hippie 250 829 111 111 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie 62 341 24 24 0
RGS7_ENST00000366563 RGS7 P49802 Regulator of G-protein signaling 7 chr1 Census, Compendium Yes 1 hippie 196 150 50 50 0
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 Not Cancer Driver No 1 hippie 35 28 2 2 5
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
TLN1 TLN1 Q9Y490 Talin-1 chr9 Not Cancer Driver No 1 hippie 278 1109 126 126 0
VCL VCL P18206 Vinculin chr10 Not Cancer Driver No 1 hippie 114 673 80 80 2
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie 84 316 57 57 1
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0