Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABCB6 | ABCB6 | Q9NP58 | ATP-binding cassette sub-family B member 6 | chr2 | Not Cancer Driver | No | 1 | hippie | 87 | 27 | 1 | 1 | 11 |
ABI1 | ABI1 | Q8IZP0 | Abl interactor 1 | chr10 | Census, Compendium | Yes | 1 | hippie | 55 | 360 | 39 | 39 | 0 |
ABL2 | ABL2 | P42684 | Tyrosine-protein kinase ABL2 | chr1 | Census, Compendium | Yes | 1 | hippie | 171 | 641 | 70 | 70 | 0 |
ACVR2B | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 70 | 14 | 14 | 2 |
ALDH3B1 | ALDH3B1 | P43353 | Aldehyde dehydrogenase family 3 member B1 | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 36 | 23 | 6 | 6 | 0 |
AMBP | AMBP | P02760 | Protein AMBP | chr9 | Not Cancer Driver | No | 1 | hippie | 57 | 61 | 15 | 15 | 0 |
AMHR2 | AMHR2 | Q16671 | Anti-Muellerian hormone type-2 receptor | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 117 | 7 | 7 | 8 |
ANKS1A | ANKS1A | Q92625 | Ankyrin repeat and SAM domain-containing protein 1A | chr6 | Not Cancer Driver | No | 1 | hippie | 120 | 756 | 75 | 75 | 0 |
AR | AR | P10275 | Androgen receptor | chrX | Census, Compendium | Yes | 1 | hippie, biogrid | 196 | 443 | 88 | 88 | 169 |
ARID4B | ARID4B | Q4LE39 | AT-rich interactive domain-containing protein 4B | chr1 | Not Cancer Driver | No | 1 | hippie | 143 | 1005 | 118 | 118 | 0 |
ARL6IP4_ENST00000543566 | ARL6IP4 | Q66PJ3-3 | Isoform 3 of ADP-ribosylation factor-like protein 6-interacting protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie | 16 | 386 | 15 | 15 | 0 |
AUNIP_ENST00000374298 | AUNIP | Q9H7T9 | Aurora kinase A and ninein-interacting protein | chr1 | Not Cancer Driver | No | 1 | hippie | 23 | 341 | 21 | 21 | 0 |
AVPR1B | AVPR1B | P47901 | Vasopressin V1b receptor | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 51 | 5 | 5 | 0 |
AXL | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | Not Cancer Driver | No | 1 | hippie | 168 | 341 | 64 | 64 | 0 |
BLK | BLK | P51451 | Tyrosine-protein kinase Blk | chr8 | Not Cancer Driver | No | 1 | hippie | 94 | 75 | 21 | 21 | 0 |
BLZF1 | BLZF1 | Q9H2G9 | Golgin-45 | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 218 | 24 | 24 | 0 |
BRK1 | BRK1 | Q8WUW1 | Protein BRICK1 | chr3 | Not Cancer Driver | No | 1 | hippie | 7 | 14 | 1 | 1 | 0 |
BTK_ENST00000308731 | BTK | Q06187 | Tyrosine-protein kinase BTK | chrX | Census, Compendium | Yes | 1 | hippie | 147 | 114 | 27 | 27 | 110 |
BTN2A1 | BTN2A1 | Q7KYR7 | Butyrophilin subfamily 2 member A1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 38 | 9 | 9 | 0 |
C16orf54 | C16orf54 | Q6UWD8 | Transmembrane protein C16orf54 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 189 | 24 | 24 | 0 |
C3orf36 | C3orf36 | Q3SXR2 | Uncharacterized protein C3orf36 | chr3 | Not Cancer Driver | No | 1 | hippie | 38 | 133 | 30 | 30 | 0 |
CAMK1 | CAMK1 | Q14012 | Calcium/calmodulin-dependent protein kinase type 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 40 | 31 | 1 | 1 | 0 |
CBL | CBL | P22681 | E3 ubiquitin-protein ligase CBL | chr11 | Census, Compendium | Yes | 1 | hippie | 115 | 512 | 56 | 56 | 4 |
CCDC14 | CCDC14 | Q49A88-6 | Isoform 6 of Coiled-coil domain-containing protein 14 | chr3 | Not Cancer Driver | No | 1 | hippie | 88 | 585 | 61 | 61 | 0 |
CCDC196 | CCDC196 | A0A1B0GTZ2 | Putative coiled-coil domain-containing protein 196 | chr14 | Not Cancer Driver | No | 1 | hippie | 10 | 224 | 8 | 8 | 0 |
CCDC33_ENST00000558821 | CCDC33 | Q8N5R6-4 | Isoform 4 of Coiled-coil domain-containing protein 33 | chr15 | Not Cancer Driver | No | 1 | hippie | 60 | 288 | 51 | 51 | 0 |
CCDC89 | CCDC89 | Q8N998 | Coiled-coil domain-containing protein 89 | chr11 | Not Cancer Driver | No | 1 | hippie | 60 | 190 | 24 | 24 | 0 |
CD19_ENST00000324662 | CD19 | P15391 | B-lymphocyte antigen CD19 | chr16 | Not Cancer Driver | No | 1 | hippie | 80 | 312 | 46 | 46 | 0 |
CEP126 | CEP126 | Q9P2H0 | Centrosomal protein of 126 kDa | chr11 | Not Cancer Driver | No | 1 | hippie | 197 | 840 | 151 | 151 | 0 |
CEP19 | CEP19 | Q96LK0 | Centrosomal protein of 19 kDa | chr3 | Not Cancer Driver | No | 1 | hippie | 30 | 71 | 11 | 11 | 0 |
CHRDL2_ENST00000376332 | CHRDL2 | Q6WN34 | Chordin-like protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 61 | 104 | 20 | 20 | 0 |
CHRM3_ENST00000615928 | CHRM3 | P20309 | Muscarinic acetylcholine receptor M3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 182 | 136 | 42 | 42 | 0 |
CLNK | CLNK | Q7Z7G1 | Cytokine-dependent hematopoietic cell linker | chr4 | Not Cancer Driver | No | 1 | hippie | 85 | 320 | 73 | 73 | 0 |
CRBN | CRBN | Q96SW2 | Protein cereblon | chr3 | Not Cancer Driver | No | 1 | hippie | 52 | 76 | 10 | 10 | 1 |
CRK | CRK | P46108 | Adapter molecule crk | chr17 | Not Cancer Driver | No | 1 | hippie | 30 | 197 | 23 | 23 | 0 |
CRYBA2 | CRYBA2 | P53672 | Beta-crystallin A2 | chr2 | Not Cancer Driver | No | 1 | hippie | 22 | 23 | 2 | 2 | 1 |
CX3CL1 | CX3CL1 | P78423 | Fractalkine | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 259 | 44 | 44 | 0 |
DCAF8 | DCAF8 | Q5TAQ9 | DDB1- and CUL4-associated factor 8 | chr1 | Not Cancer Driver | No | 1 | hippie | 85 | 273 | 55 | 55 | 1 |
DDR1_ENST00000324771 | DDR1 | Q08345 | Epithelial discoidin domain-containing receptor 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 123 | 253 | 49 | 49 | 0 |
DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | Not Cancer Driver | No | 1 | hippie | 132 | 514 | 82 | 82 | 0 |
DNAJC5 | DNAJC5 | Q9H3Z4 | DnaJ homolog subfamily C member 5 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 46 | 6 | 6 | 1 |
DOCK5 | DOCK5 | Q9H7D0 | Dedicator of cytokinesis protein 5 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 278 | 330 | 45 | 45 | 0 |
DRAP1 | DRAP1 | Q14919 | Dr1-associated corepressor | chr11 | Not Cancer Driver | No | 1 | hippie | 28 | 170 | 22 | 22 | 0 |
DSN1 | DSN1 | Q9H410 | Kinetochore-associated protein DSN1 homolog | chr20 | Not Cancer Driver | No | 1 | hippie | 45 | 191 | 28 | 28 | 0 |
E2F6 | E2F6 | O75461 | Transcription factor E2F6 | chr2 | Not Cancer Driver | No | 1 | hippie | 20 | 105 | 10 | 10 | 0 |
EFNB2_ENST00000245323 | EFNB2 | P52799 | Ephrin-B2 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 97 | 15 | 15 | 0 |
EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 2 | hippie, biogrid | 444 | 223 | 35 | 35 | 1 |
EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
EHD2 | EHD2 | Q9NZN4 | EH domain-containing protein 2 | chr19 | Compendium | Yes | 2 | hippie, biogrid | 85 | 125 | 12 | 12 | 0 |
ENKD1 | ENKD1 | Q9H0I2 | Enkurin domain-containing protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 40 | 307 | 34 | 34 | 0 |
ERBB2 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | Census, Compendium | Yes | 2 | hippie, biogrid | 275 | 314 | 41 | 41 | 1 |
ERBB3 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | Census, Compendium | Yes | 2 | hippie, biogrid | 298 | 396 | 70 | 70 | 3 |
ERBB4 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | Census, Compendium | Yes | 1 | hippie, biogrid | 428 | 323 | 116 | 116 | 2 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
FAM166B | FAM166B | A8MTA8 | Protein FAM166B | chr9 | Not Cancer Driver | No | 1 | hippie | 27 | 140 | 14 | 14 | 0 |
FAM208B | TASOR2 | Q5VWN6 | Protein TASOR 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 226 | 1431 | 127 | 127 | 0 |
FBN3_ENST00000601739 | FBN3 | Q75N90 | Fibrillin-3 | chr19 | Not Cancer Driver | No | 1 | hippie | 454 | 102 | 25 | 25 | 0 |
FER | FER | P16591 | Tyrosine-protein kinase Fer | chr5 | Not Cancer Driver | No | 1 | hippie | 114 | 145 | 21 | 21 | 0 |
FGB | FGB | P02675 | Fibrinogen beta chain | chr4 | Not Cancer Driver | No | 1 | hippie | 89 | 143 | 29 | 29 | 7 |
FLRT1 | FLRT1 | Q9NZU1 | Leucine-rich repeat transmembrane protein FLRT1 | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 74 | 90 | 9 | 9 | 0 |
FNDC8 | FNDC8 | Q8TC99 | Fibronectin type III domain-containing protein 8 | chr17 | Not Cancer Driver | No | 1 | hippie | 41 | 138 | 19 | 19 | 0 |
FOXO1 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | Census, Compendium | Yes | 1 | hippie | 81 | 584 | 75 | 75 | 0 |
FRS3_ENST00000259748 | FRS3 | O43559 | Fibroblast growth factor receptor substrate 3 | chr6 | Not Cancer Driver | No | 1 | hippie | 77 | 388 | 58 | 58 | 0 |
FSD2 | FSD2 | A1L4K1 | Fibronectin type III and SPRY domain-containing protein 2 | chr15 | Not Cancer Driver | No | 1 | hippie | 116 | 300 | 60 | 60 | 0 |
FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | Not Cancer Driver | No | 1 | hippie | 92 | 70 | 13 | 13 | 0 |
GAB1_ENST00000262994 | GAB1 | Q13480 | GRB2-associated-binding protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 570 | 68 | 68 | 1 |
GC_ENST00000273951 | GC | P02774 | Vitamin D-binding protein | chr4 | Not Cancer Driver | No | 1 | hippie | 93 | 13 | 3 | 3 | 0 |
GRB2_ENST00000392564 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 28 | 10 | 1 | 1 | 0 |
HAVCR2 | HAVCR2 | Q8TDQ0 | Hepatitis A virus cellular receptor 2 | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 69 | 17 | 2 | 2 | 3 |
HCK_ENST00000534862 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | Not Cancer Driver | No | 1 | hippie | 112 | 124 | 25 | 25 | 0 |
HEPACAM2_ENST00000394468 | HEPACAM2 | A8MVW5 | HEPACAM family member 2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 115 | 50 | 14 | 14 | 0 |
HNRNPL | HNRNPL | P14866 | Heterogeneous nuclear ribonucleoprotein L | chr19 | Not Cancer Driver | No | 1 | hippie | 89 | 283 | 29 | 29 | 0 |
HSH2D | HSH2D | Q96JZ2 | Hematopoietic SH2 domain-containing protein | chr19 | Not Cancer Driver | No | 1 | hippie | 44 | 233 | 38 | 38 | 0 |
HTT | HTT | P42858 | Huntingtin | chr4 | Not Cancer Driver | No | 1 | hippie | 336 | 666 | 69 | 69 | 2 |
IGF1R | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | Not Cancer Driver | No | 1 | hippie | 183 | 265 | 37 | 37 | 6 |
IL20RA | IL20RA | Q9UHF4 | Interleukin-20 receptor subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 231 | 29 | 29 | 0 |
INSR | INSR | P06213 | Insulin receptor | chr19 | Not Cancer Driver | No | 1 | hippie | 190 | 280 | 57 | 57 | 64 |
IQUB_ENST00000324698 | IQUB | Q8NA54 | IQ and ubiquitin-like domain-containing protein | chr7 | Not Cancer Driver | No | 1 | hippie | 152 | 156 | 35 | 35 | 0 |
IRS1 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 161 | 1072 | 133 | 133 | 2 |
IRS2 | IRS2 | Q9Y4H2 | Insulin receptor substrate 2 | chr13 | Not Cancer Driver | No | 3 | hippie, biogrid | 69 | 1112 | 57 | 57 | 0 |
IRS4 | IRS4 | O14654 | Insulin receptor substrate 4 | chrX | Census, Compendium | Yes | 2 | hippie, biogrid | 297 | 798 | 203 | 203 | 0 |
ITGB3BP_ENST00000271002 | ITGB3BP | Q13352 | Centromere protein R | chr1 | Not Cancer Driver | No | 1 | hippie | 19 | 122 | 14 | 14 | 0 |
KCNE3 | KCNE3 | Q9Y6H6 | Potassium voltage-gated channel subfamily E member 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 24 | 2 | 2 | 0 |
KHDRBS1 | KHDRBS1 | Q07666 | KH domain-containing, RNA-binding, signal transduction-associated protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 53 | 362 | 43 | 43 | 0 |
KIAA0408 | KIAA0408 | Q6ZU52 | Uncharacterized protein KIAA0408 | chr6 | Not Cancer Driver | No | 1 | hippie | 112 | 607 | 94 | 94 | 0 |
KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | Census, Compendium | Yes | 1 | hippie, biogrid | 226 | 83 | 33 | 33 | 21 |
KLC2_ENST00000394067 | KLC2 | Q9H0B6 | Kinesin light chain 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 75 | 344 | 49 | 49 | 0 |
KLF15 | KLF15 | Q9UIH9 | Krueppel-like factor 15 | chr3 | Not Cancer Driver | No | 1 | hippie | 66 | 273 | 48 | 48 | 0 |
KMT2B | KMT2B | Q9UMN6 | Histone-lysine N-methyltransferase 2B | chr19 | Compendium | Yes | 1 | hippie | 378 | 1895 | 227 | 227 | 0 |
L3MBTL3_ENST00000368136 | L3MBTL3 | Q96JM7 | Lethal(3)malignant brain tumor-like protein 3 | chr6 | Not Cancer Driver | No | 1 | hippie | 117 | 351 | 59 | 59 | 0 |
LAMP1 | LAMP1 | P11279 | Lysosome-associated membrane glycoprotein 1 | chr13 | Not Cancer Driver | No | 2 | hippie, biogrid | 47 | 93 | 10 | 10 | 0 |
LAP3 | LAP3 | P28838 | Cytosol aminopeptidase | chr4 | Not Cancer Driver | No | 1 | hippie | 59 | 99 | 14 | 14 | 0 |
LNX2 | LNX2 | Q8N448 | Ligand of Numb protein X 2 | chr13 | Not Cancer Driver | No | 1 | hippie | 85 | 277 | 35 | 35 | 0 |
LUC7L2 | LUC7L2 | Q9Y383 | Putative RNA-binding protein Luc7-like 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 59 | 262 | 45 | 45 | 0 |
LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | Census | Yes | 1 | hippie | 95 | 84 | 12 | 12 | 0 |
MANSC1 | MANSC1 | Q9H8J5 | MANSC domain-containing protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 206 | 21 | 21 | 0 |
MBIP | MBIP | Q9NS73 | MAP3K12-binding inhibitory protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 47 | 190 | 20 | 20 | 0 |
MECOM_ENST00000494292 | MECOM | Q03112 | Histone-lysine N-methyltransferase MECOM | chr3 | Census, Compendium | Yes | 1 | hippie | 287 | 749 | 159 | 159 | 3 |
METTL27 | METTL27 | Q8N6F8 | Methyltransferase-like protein 27 | chr7 | Not Cancer Driver | No | 1 | hippie | 36 | 47 | 8 | 8 | 0 |
MET_ENST00000397752 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie, biogrid | 226 | 62 | 15 | 15 | 19 |
MICAL1_ENST00000358807 | MICAL1 | Q8TDZ2 | [F-actin]-monooxygenase MICAL1 | chr6 | Not Cancer Driver | No | 1 | hippie | 112 | 364 | 37 | 37 | 0 |
MTF2 | MTF2 | Q9Y483 | Metal-response element-binding transcription factor 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 70 | 225 | 28 | 28 | 0 |
NAB2 | NAB2 | Q15742 | NGFI-A-binding protein 2 | chr12 | Census | Yes | 1 | hippie | 67 | 395 | 51 | 51 | 0 |
NCK1_ENST00000288986 | NCK1 | P16333 | Cytoplasmic protein NCK1 | chr3 | Not Cancer Driver | No | 1 | hippie | 48 | 111 | 17 | 17 | 0 |
NEBL | NEBL | O76041 | Nebulette | chr10 | Not Cancer Driver | No | 1 | hippie | 239 | 773 | 183 | 183 | 0 |
NEDD9 | NEDD9 | Q14511 | Enhancer of filamentation 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 106 | 516 | 72 | 72 | 0 |
NISCH_ENST00000479054 | NISCH | Q9Y2I1 | Nischarin | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 160 | 418 | 43 | 43 | 0 |
NLGN3 | NLGN3 | Q9NZ94 | Neuroligin-3 | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 158 | 257 | 54 | 54 | 2 |
OLFM3 | OLFM3 | Q96PB7 | Noelin-3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 148 | 44 | 17 | 17 | 0 |
OLIG1 | OLIG1 | Q8TAK6 | Oligodendrocyte transcription factor 1 | chr21 | Not Cancer Driver | No | 1 | hippie | 6 | 130 | 1 | 1 | 0 |
ORM1 | ORM1 | P02763 | Alpha-1-acid glycoprotein 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 38 | 23 | 2 | 2 | 0 |
OTUD7B | OTUD7B | Q6GQQ9 | OTU domain-containing protein 7B | chr1 | Not Cancer Driver | No | 1 | hippie | 124 | 537 | 87 | 87 | 0 |
PACRGL | PACRGL | Q8N7B6 | PACRG-like protein | chr4 | Not Cancer Driver | No | 1 | hippie | 43 | 73 | 10 | 10 | 0 |
PARD6A | PARD6A | Q9NPB6 | Partitioning defective 6 homolog alpha | chr16 | Not Cancer Driver | No | 1 | hippie | 25 | 177 | 13 | 13 | 0 |
PBX4 | PBX4 | Q9BYU1 | Pre-B-cell leukemia transcription factor 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 47 | 262 | 26 | 26 | 0 |
PCDHB5 | PCDHB5 | Q9Y5E4 | Protocadherin beta-5 | chr5 | Not Cancer Driver | No | 1 | hippie | 271 | 185 | 61 | 61 | 0 |
PDGFRB | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | Census, Compendium | Yes | 1 | hippie | 164 | 231 | 44 | 44 | 7 |
PELI3 | PELI3 | Q8N2H9 | E3 ubiquitin-protein ligase pellino homolog 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 48 | 216 | 25 | 25 | 0 |
PELO | PELO | Q9BRX2 | Protein pelota homolog | chr5 | Not Cancer Driver | No | 1 | hippie | 38 | 67 | 10 | 10 | 0 |
PIBF1 | PIBF1 | Q8WXW3 | Progesterone-induced-blocking factor 1 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 419 | 45 | 45 | 2 |
PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | Census, Compendium | Yes | 3 | hippie, biogrid | 1669 | 38 | 11 | 11 | 30 |
PIK3CB_ENST00000477593 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | Census, Compendium | Yes | 3 | hippie, biogrid | 150 | 42 | 4 | 4 | 0 |
PIK3CD | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 140 | 60 | 13 | 13 | 1 |
PIK3R1 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | Census, Compendium | Yes | 2 | hippie, biogrid | 154 | 268 | 61 | 61 | 2 |
PIK3R2_ENST00000617130 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | Not Cancer Driver | No | 4 | hippie, biogrid | 96 | 418 | 47 | 47 | 3 |
PLB1 | PLB1 | Q6P1J6 | Phospholipase B1, membrane-associated | chr2 | Not Cancer Driver | No | 1 | hippie | 223 | 399 | 57 | 57 | 0 |
PLEKHF2 | PLEKHF2 | Q9H8W4 | Pleckstrin homology domain-containing family F member 2 | chr8 | Not Cancer Driver | No | 1 | hippie | 32 | 36 | 4 | 4 | 0 |
PLEKHS1 | PLEKHS1 | Q5SXH7 | Pleckstrin homology domain-containing family S member 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 79 | 227 | 41 | 41 | 0 |
PPARA_ENST00000402126 | PPARA | Q07869 | Peroxisome proliferator-activated receptor alpha | chr22 | Not Cancer Driver | No | 1 | hippie | 63 | 68 | 9 | 9 | 0 |
PPP1R12B_ENST00000608999 | PPP1R12B | O60237 | Protein phosphatase 1 regulatory subunit 12B | chr1 | Not Cancer Driver | No | 1 | hippie | 143 | 801 | 119 | 119 | 0 |
PRKAR1B_ENST00000403562 | PRKAR1B | P31321 | cAMP-dependent protein kinase type I-beta regulatory subunit | chr7 | Not Cancer Driver | No | 1 | hippie | 53 | 71 | 13 | 13 | 0 |
PSME1_ENST00000206451 | PSME1 | Q06323 | Proteasome activator complex subunit 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 20 | 80 | 8 | 8 | 0 |
PTK2_ENST00000522684 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 134 | 425 | 55 | 55 | 0 |
PTP4A3_ENST00000521578 | PTP4A3 | O75365 | Protein tyrosine phosphatase type IVA 3 | chr8 | Not Cancer Driver | No | 1 | hippie | 30 | 3 | 0 | 0 | 0 |
PWP1 | PWP1 | Q13610 | Periodic tryptophan protein 1 homolog | chr12 | Not Cancer Driver | No | 1 | hippie | 51 | 186 | 22 | 22 | 0 |
RAB11A | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | Not Cancer Driver | No | 1 | hippie | 31 | 43 | 4 | 4 | 0 |
RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
RB1 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | Census, Compendium | Yes | 1 | hippie | 140 | 282 | 32 | 32 | 22 |
RBP7 | RBP7 | Q96R05 | Retinoid-binding protein 7 | chr1 | Not Cancer Driver | No | 1 | hippie | 13 | 0 | 0 | 0 | 0 |
RELT | RELT | Q969Z4 | Tumor necrosis factor receptor superfamily member 19L | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 239 | 18 | 18 | 0 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
RHOQ | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
RING1 | RING1 | Q06587 | E3 ubiquitin-protein ligase RING1 | chr6 | Not Cancer Driver | No | 1 | hippie | 60 | 302 | 44 | 44 | 0 |
RIPK4_ENST00000352483 | RIPK4 | P57078 | Receptor-interacting serine/threonine-protein kinase 4 | chr21 | Not Cancer Driver | No | 1 | hippie | 119 | 232 | 34 | 34 | 3 |
RUSC1 | RUSC1 | Q9BVN2 | AP-4 complex accessory subunit RUSC1 | chr1 | Not Cancer Driver | No | 1 | hippie | 99 | 640 | 69 | 69 | 0 |
SERF1B | SERF1B | O75920 | Small EDRK-rich factor 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 2 | 61 | 1 | 1 | 0 |
SERTAD2 | SERTAD2 | Q14140 | SERTA domain-containing protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 37 | 258 | 31 | 31 | 0 |
SH2D2A_ENST00000368199 | SH2D2A | Q9NP31 | SH2 domain-containing protein 2A | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 272 | 42 | 42 | 0 |
SKAP1_ENST00000584924 | SKAP1 | Q86WV1 | Src kinase-associated phosphoprotein 1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 130 | 27 | 27 | 0 |
SLC31A1 | SLC31A1 | O15431 | High affinity copper uptake protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 28 | 6 | 6 | 0 |
SOCS4_ENST00000555846 | SOCS4 | Q8WXH5 | Suppressor of cytokine signaling 4 | chr14 | Not Cancer Driver | No | 1 | hippie | 43 | 136 | 13 | 13 | 0 |
SOCS6_ENST00000582322 | SOCS6 | O14544 | Suppressor of cytokine signaling 6 | chr18 | Not Cancer Driver | No | 2 | hippie, biogrid | 81 | 299 | 48 | 48 | 0 |
SPATA32 | SPATA32 | Q96LK8 | Spermatogenesis-associated protein 32 | chr17 | Not Cancer Driver | No | 1 | hippie | 41 | 327 | 36 | 36 | 0 |
SPSB2_ENST00000523102 | SPSB2 | Q99619 | SPRY domain-containing SOCS box protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 30 | 108 | 12 | 12 | 0 |
SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | Census | Yes | 1 | hippie | 53 | 130 | 11 | 11 | 1 |
SSBP4 | SSBP4 | Q9BWG4 | Single-stranded DNA-binding protein 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 32 | 316 | 21 | 21 | 0 |
STAT3 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | Census, Compendium | Yes | 1 | hippie | 110 | 152 | 15 | 15 | 19 |
STAT5B | STAT5B | P51692 | Signal transducer and activator of transcription 5B | chr17 | Census, Compendium | Yes | 1 | hippie | 93 | 144 | 19 | 19 | 5 |
TEC | TEC | P42680 | Tyrosine-protein kinase Tec | chr4 | Census, Compendium | Yes | 1 | hippie | 91 | 57 | 15 | 15 | 0 |
TERF2 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 33 | 361 | 20 | 20 | 0 |
TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | Census, Compendium | Yes | 3 | hippie, biogrid | 106 | 60 | 16 | 16 | 25 |
TMEM52B | TMEM52B | Q4KMG9 | Transmembrane protein 52B | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 45 | 34 | 10 | 10 | 0 |
TNK2_ENST00000333602 | TNK2 | Q07912 | Activated CDC42 kinase 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 137 | 593 | 81 | 81 | 0 |
TNNC2 | TNNC2 | P02585 | Troponin C, skeletal muscle | chr20 | Not Cancer Driver | No | 1 | hippie | 26 | 87 | 13 | 13 | 0 |
TNNI1_ENST00000336092 | TNNI1 | P19237 | Troponin I, slow skeletal muscle | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 72 | 8 | 8 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
TRIM54_ENST00000380075 | TRIM54 | Q9BYV2 | Tripartite motif-containing protein 54 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 63 | 98 | 17 | 17 | 0 |
TRIM66_ENST00000299550 | TRIM66 | O15016 | Tripartite motif-containing protein 66 | chr11 | Not Cancer Driver | No | 1 | hippie | 58 | 723 | 32 | 32 | 0 |
TRMT2A_ENST00000403707 | TRMT2A | Q8IZ69 | tRNA (uracil-5-)-methyltransferase homolog A | chr22 | Not Cancer Driver | No | 1 | hippie | 64 | 157 | 20 | 20 | 0 |
TSPAN2 | TSPAN2 | O60636 | Tetraspanin-2 | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
USP2 | USP2 | O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 88 | 213 | 39 | 39 | 0 |
VBP1 | VBP1 | P61758 | Prefoldin subunit 3 | chrX | Not Cancer Driver | No | 1 | hippie | 27 | 47 | 7 | 7 | 0 |
VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 186 | 16 | 16 | 16 |
VSIG4 | VSIG4 | Q9Y279 | V-set and immunoglobulin domain-containing protein 4 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 70 | 13 | 13 | 0 |
WDFY3 | WDFY3 | Q8IZQ1 | WD repeat and FYVE domain-containing protein 3 | chr4 | Not Cancer Driver | No | 1 | hippie | 455 | 605 | 73 | 73 | 1 |
WRNIP1 | WRNIP1 | Q96S55 | ATPase WRNIP1 | chr6 | Not Cancer Driver | No | 1 | hippie | 50 | 292 | 7 | 7 | 0 |
YES1_ENST00000314574 | YES1 | P07947 | Tyrosine-protein kinase Yes | chr18 | Not Cancer Driver | No | 1 | hippie | 65 | 62 | 10 | 10 | 0 |
YPEL3_ENST00000566595 | YPEL3 | P61236 | Protein yippee-like 3 | chr16 | Not Cancer Driver | No | 1 | hippie | 13 | 0 | 0 | 0 | 0 |
ZBTB18_ENST00000622512 | ZBTB18 | Q99592 | Zinc finger and BTB domain-containing protein 18 | chr1 | Not Cancer Driver | No | 1 | hippie | 78 | 236 | 25 | 25 | 0 |
ZMAT1_ENST00000540921 | ZMAT1 | Q5H9K5 | Zinc finger matrin-type protein 1 | chrX | Not Cancer Driver | No | 1 | hippie | 131 | 388 | 80 | 80 | 0 |
ZNF281_ENST00000367353 | ZNF281 | Q9Y2X9 | Zinc finger protein 281 | chr1 | Not Cancer Driver | No | 1 | hippie | 92 | 709 | 67 | 67 | 0 |
ZNF451 | ZNF451 | Q9Y4E5 | E3 SUMO-protein ligase ZNF451 | chr6 | Not Cancer Driver | No | 1 | hippie | 169 | 191 | 25 | 25 | 0 |
ZNF620 | ZNF620 | Q6ZNG0 | Zinc finger protein 620 | chr3 | Not Cancer Driver | No | 1 | hippie | 50 | 125 | 17 | 17 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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