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PIK3C2B ,PIK3C2B ,O00750
  • Uniprot Accession= O00750
  • Ensembl Transcript= ENST00000367187.7
  • Uniprot Name= PIK3C2B
  • Name= Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 20
  • Number of Interaction partner in hippie: 39
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ALPL ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 Not Cancer Driver No 1 biogrid 80 184 39 39 113
AOC3 AOC3 Q16853 Membrane primary amine oxidase chr17 Not Cancer Driver No 1 biogrid 112 101 13 13 0
BIRC5_ENST00000350051 BIRC5 O15392 Baculoviral IAP repeat-containing protein 5 chr17 Not Cancer Driver No 1 biogrid 20 49 6 6 0
CARM1 CARM1 Q86X55 Histone-arginine methyltransferase CARM1 chr19 Not Cancer Driver No 1 biogrid 62 102 10 10 0
CEP135 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 Not Cancer Driver No 1 hippie, biogrid 127 690 72 72 0
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 hippie 132 514 82 82 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FABP4 FABP4 P15090 Fatty acid-binding protein, adipocyte chr8 Not Cancer Driver No 1 biogrid 14 4 0 0 0
FAM189A2 FAM189A2 Q15884 Protein FAM189A2 chr9 Not Cancer Driver No 1 hippie 62 231 29 29 0
FAN1 FAN1 Q9Y2M0 Fanconi-associated nuclease 1 chr15 Not Cancer Driver No 1 intact, hippie 124 212 27 27 4
FASN FASN P49327 Fatty acid synthase chr17 Not Cancer Driver No 1 hippie, biogrid 291 309 42 42 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 3 hippie, biogrid 28 10 1 1 0
HCRTR1 HCRTR1 O43613 Orexin/Hypocretin receptor type 1 chr1 Not Cancer Driver No 1 biogrid 52 28 0 0 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
ITSN1 ITSN1 Q15811 Intersectin-1 chr21 Not Cancer Driver No 1 hippie 214 797 107 107 0
ITSN2 ITSN2 Q9NZM3 Intersectin-2 chr2 Not Cancer Driver No 1 hippie 207 680 92 92 0
KLHL2_ENST00000226725 KLHL2 O95198 Kelch-like protein 2 chr4 Not Cancer Driver No 2 hippie, biogrid 80 42 5 5 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 biogrid 86 94 13 13 1
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 Not Cancer Driver No 1 hippie 103 301 30 30 0
MIB1 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 Not Cancer Driver No 1 hippie 122 282 34 34 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 hippie 48 111 17 17 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 Census Yes 1 hippie 227 1008 107 107 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 Census, Compendium Yes 1 hippie 164 231 44 44 7
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie 154 268 61 61 2
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 26 32 11 11 0
SF1_ENST00000377390 SF1 Q15637 Splicing factor 1 chr11 Not Cancer Driver No 1 hippie 110 627 106 106 0
SFN SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 27 75 9 9 0
SH3YL1 SH3YL1 Q96HL8 SH3 domain-containing YSC84-like protein 1 chr2 Not Cancer Driver No 2 hippie, biogrid 35 108 11 11 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 84 397 58 58 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie, biogrid 54 267 32 32 30
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 hippie 59 87 11 11 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 2 hippie, biogrid 22 109 4 4 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 hippie, biogrid 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 2 hippie, biogrid 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 2 hippie, biogrid 30 81 10 10 0