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PIGR ,PIGR ,P01833
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 61
  • Number of Interaction partner in hippie: 123
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AEBP2 AEBP2 Q6ZN18 Zinc finger protein AEBP2 chr12 Not Cancer Driver No 1 hippie 41 335 25 25 0
AP1M1_ENST00000291439 AP1M1 Q9BXS5 AP-1 complex subunit mu-1 chr19 Not Cancer Driver No 1 hippie 64 38 12 12 0
ARMC6 ARMC6 Q6NXE6 Armadillo repeat-containing protein 6 chr19 Not Cancer Driver No 1 hippie, biogrid 65 77 5 5 0
ATP11C ATP11C Q8NB49 Phospholipid-transporting ATPase IG chrX Not Cancer Driver No 1 hippie, biogrid 198 32 5 5 1
C10orf53_ENST00000374111 C10orf53 Q8N6V4 UPF0728 protein C10orf53 chr10 Not Cancer Driver No 1 hippie, biogrid 12 0 0 0 0
CD79A CD79A P11912 B-cell antigen receptor complex-associated protein alpha chain chr19 Census Yes 1 hippie 32 28 3 3 0
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 Census Yes 1 hippie 40 24 3 3 1
CHAC2 CHAC2 Q8WUX2 Glutathione-specific gamma-glutamylcyclotransferase 2 chr2 Not Cancer Driver No 1 hippie, biogrid 21 11 2 2 0
CLCN2 CLCN2 P51788 Chloride channel protein 2 chr3 Not Cancer Driver No 1 hippie, biogrid 124 224 38 38 8
CLK1_ENST00000321356 CLK1 P49759 Dual specificity protein kinase CLK1 chr2 Not Cancer Driver No 1 hippie, biogrid 64 131 21 21 0
COG2 COG2 Q14746 Conserved oligomeric Golgi complex subunit 2 chr1 Not Cancer Driver No 1 hippie, biogrid 90 105 16 16 1
COMMD1 COMMD1 Q8N668 COMM domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 21 17 0 0 0
CRYGN CRYGN Q8WXF5 Gamma-crystallin N chr7 Not Cancer Driver No 1 hippie, biogrid 32 33 6 6 0
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
DDX31_ENST00000372153 DDX31 Q9H8H2 Probable ATP-dependent RNA helicase DDX31 chr9 Not Cancer Driver No 2 hippie, biogrid 99 342 38 38 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX Census, Compendium Yes 1 hippie 133 301 47 47 18
EBF2 EBF2 Q9HAK2 Transcription factor COE2 chr8 Not Cancer Driver No 1 hippie, biogrid 158 261 71 71 0
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 Not Cancer Driver No 1 hippie 74 121 17 17 3
EGFL8 EGFL8 Q99944 Epidermal growth factor-like protein 8 chr6 Not Cancer Driver No 1 hippie, biogrid 37 56 10 10 0
EPB41L3 EPB41L3 Q9Y2J2 Band 4.1-like protein 3 chr18 Not Cancer Driver No 1 hippie 298 695 207 207 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FCN1 FCN1 O00602 Ficolin-1 chr9 Not Cancer Driver No 1 hippie, biogrid 107 88 15 15 0
FKBP14 FKBP14 Q9NWM8 Peptidyl-prolyl cis-trans isomerase FKBP14 chr7 Not Cancer Driver No 1 hippie, biogrid 24 23 1 1 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 hippie 416 1456 214 214 28
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 Not Cancer Driver No 1 hippie 362 1183 170 170 19
FLNC FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 1 hippie 546 1442 288 288 7
FN3KRP FN3KRP Q9HA64 Ketosamine-3-kinase chr17 Not Cancer Driver No 1 hippie, biogrid 36 75 5 5 0
FNDC5_ENST00000640867 FNDC5 Q8NAU1 Fibronectin type III domain-containing protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 17 74 8 8 0
FOXN3 FOXN3 O00409 Forkhead box protein N3 chr14 Not Cancer Driver No 1 hippie, biogrid 76 365 61 61 0
FRMD1 FRMD1 Q8N878 FERM domain-containing protein 1 chr6 Not Cancer Driver No 2 hippie, biogrid 82 259 36 36 0
GJB5 GJB5 O95377 Gap junction beta-5 protein chr1 Not Cancer Driver No 1 hippie, biogrid 38 8 5 5 0
GKN1 GKN1 A0A8I5KHR1 Gastrokine-1 chr2 Not Cancer Driver No 1 hippie, biogrid 37 50 7 7 0
GNG8 GNG8 Q9UK08 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 chr19 Not Cancer Driver No 1 hippie, biogrid 2 16 1 1 0
GOLGA8A_ENST00000432566 GOLGA8A A7E2F4 Golgin subfamily A member 8A chr15 Not Cancer Driver No 1 hippie, biogrid 25 565 22 22 0
GTF2B GTF2B Q00403 Transcription initiation factor IIB chr1 Not Cancer Driver No 3 hippie, biogrid 33 80 6 6 0
HBM HBM Q6B0K9 Hemoglobin subunit mu chr16 Not Cancer Driver No 2 hippie, biogrid 9 0 0 0 0
HBQ1 HBQ1 P09105 Hemoglobin subunit theta-1 chr16 Not Cancer Driver No 1 hippie, biogrid 10 0 0 0 0
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 10 29 2 2 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HVCN1_ENST00000620084 HVCN1 Q96D96 Voltage-gated hydrogen channel 1 chr12 Not Cancer Driver No 2 hippie, biogrid 51 52 13 13 0
ICE2 ICE2 Q659A1 Little elongation complex subunit 2 chr15 Not Cancer Driver No 3 hippie, biogrid 107 399 45 45 0
ITLN2 ITLN2 Q8WWU7 Intelectin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 56 21 4 4 0
ITPRID2 ITPRID2 P28290 Protein ITPRID2 chr2 Not Cancer Driver No 1 hippie 158 1006 129 129 0
KCTD21 KCTD21 Q4G0X4 BTB/POZ domain-containing protein KCTD21 chr11 Not Cancer Driver No 1 hippie 40 11 0 0 0
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 Not Cancer Driver No 1 hippie, biogrid 66 273 48 48 0
KLK10_ENST00000358789 KLK10 O43240 Kallikrein-10 chr19 Not Cancer Driver No 1 hippie, biogrid 35 30 8 8 0
KMT2C_ENST00000355193 KMT2C Q8NEZ4 Histone-lysine N-methyltransferase 2C chr7 Census, Compendium Yes 1 hippie 835 3599 517 517 0
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 Not Cancer Driver No 1 hippie 133 426 98 98 20
KRT10 KRT10 P13645 Keratin, type I cytoskeletal 10 chr17 Not Cancer Driver No 1 hippie 79 297 38 38 16
KRT2 KRT2 P35908 Keratin, type II cytoskeletal 2 epidermal chr12 Not Cancer Driver No 1 hippie 122 335 59 59 15
KRT9 KRT9 P35527 Keratin, type I cytoskeletal 9 chr17 Not Cancer Driver No 1 hippie 104 427 68 68 21
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 hippie 114 404 58 58 0
LAMA2 LAMA2 P24043 Laminin subunit alpha-2 chr6 Not Cancer Driver No 1 hippie 629 658 127 127 11
LGALS1 LGALS1 P09382 Galectin-1 chr22 Not Cancer Driver No 1 hippie, biogrid 16 0 0 0 0
LNX1 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 hippie 117 261 40 40 0
LOXL4 LOXL4 Q96JB6 Lysyl oxidase homolog 4 chr10 Not Cancer Driver No 1 hippie, biogrid 95 122 11 11 0
LRRC8E LRRC8E Q6NSJ5 Volume-regulated anion channel subunit LRRC8E chr19 Not Cancer Driver No 1 hippie, biogrid 77 35 0 0 0
LUM LUM P51884 Lumican chr12 Not Cancer Driver No 1 hippie 108 1 0 0 0
MAGEB4 MAGEB4 O15481 Melanoma-associated antigen B4 chrX Not Cancer Driver No 1 hippie, biogrid 100 186 54 54 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 Not Cancer Driver No 1 hippie 81 235 37 37 0
MCCC1 MCCC1 Q96RQ3 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial chr3 Not Cancer Driver No 1 hippie 94 162 17 17 33
MIS12 MIS12 Q9H081 Protein MIS12 homolog chr17 Not Cancer Driver No 1 hippie 14 15 2 2 0
MYRFL MYRFL Q96LU7 Myelin regulatory factor-like protein chr12 Not Cancer Driver No 1 hippie 8 316 2 2 0
NBEA NBEA Q8NFP9 Neurobeachin chr13 Census, Compendium Yes 1 hippie 537 717 134 134 4
NHLRC2 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 74 103 12 12 0
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 230 881 150 150 0
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 Census, Compendium Yes 1 hippie 282 630 77 77 1
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 Not Cancer Driver No 1 hippie, biogrid 123 0 0 0 0
NPB NPB Q8NG41 Neuropeptide B chr17 Not Cancer Driver No 2 hippie, biogrid 6 22 1 1 0
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 Census, Compendium Yes 1 hippie 234 1864 203 203 0
NXT1 NXT1 Q9UKK6 NTF2-related export protein 1 chr20 Not Cancer Driver No 1 hippie, biogrid 16 0 0 0 0
PC PC P11498 Pyruvate carboxylase, mitochondrial chr11 Not Cancer Driver No 1 hippie 185 172 27 27 9
PCCA PCCA P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial chr13 Not Cancer Driver No 1 hippie 102 42 14 14 16
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 91 139 13 13 0
PI4KB_ENST00000368873 PI4KB Q9UBF8 Phosphatidylinositol 4-kinase beta chr1 Not Cancer Driver No 1 hippie 93 311 34 34 0
PIGR PIGR P01833 Polymeric immunoglobulin receptor chr1 Not Cancer Driver No 1 hippie 126 177 37 37 0
PLEKHG6_ENST00000011684 PLEKHG6 Q3KR16 Pleckstrin homology domain-containing family G member 6 chr12 Not Cancer Driver No 1 hippie, biogrid 103 471 65 65 0
PMEPA1 PMEPA1 Q969W9 Protein TMEPAI chr20 Not Cancer Driver No 1 hippie, biogrid 45 196 34 34 0
POTEF POTEF A5A3E0 POTE ankyrin domain family member F chr2 Not Cancer Driver No 1 hippie 269 453 93 93 0
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 Not Cancer Driver No 1 hippie 22 40 5 5 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 Not Cancer Driver No 1 hippie 128 98 26 26 0
PRKAB2 PRKAB2 O43741 5'-AMP-activated protein kinase subunit beta-2 chr1 Not Cancer Driver No 1 hippie 31 110 12 12 0
PRKX PRKX P51817 cAMP-dependent protein kinase catalytic subunit PRKX chrX Not Cancer Driver No 1 hippie, biogrid 54 69 3 3 0
PRSS58_ENST00000547058 PRSS58 Q8IYP2 Serine protease 58 chr7 Not Cancer Driver No 1 hippie 81 0 0 0 0
RAB11FIP1 RAB11FIP1 Q6WKZ4 Rab11 family-interacting protein 1 chr8 Not Cancer Driver No 1 hippie 145 1118 133 133 0
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 Not Cancer Driver No 1 hippie 83 533 70 70 0
RAB3B RAB3B P20337 Ras-related protein Rab-3B chr1 Not Cancer Driver No 1 hippie 36 25 6 6 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 1 hippie 115 421 74 74 3
RHOBTB1 RHOBTB1 O94844 Rho-related BTB domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 95 121 19 19 0
RIBC1 RIBC1 Q8N443 RIB43A-like with coiled-coils protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 37 303 32 32 0
RING1 RING1 Q06587 E3 ubiquitin-protein ligase RING1 chr6 Not Cancer Driver No 1 hippie, biogrid 60 302 44 44 0
RPL11 RPL11 P62913 60S ribosomal protein L11 chr1 Not Cancer Driver No 1 hippie 27 12 1 1 1
SCAMP2 SCAMP2 O15127 Secretory carrier-associated membrane protein 2 chr15 Not Cancer Driver No 1 hippie, biogrid 34 111 9 9 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 Not Cancer Driver No 1 hippie 196 1064 135 135 2
SDHB SDHB P21912 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial chr1 Census Yes 1 hippie 37 17 3 3 23
SEC24C SEC24C P53992 Protein transport protein Sec24C chr10 Not Cancer Driver No 1 hippie 121 402 38 38 0
SFXN4 SFXN4 Q6P4A7 Sideroflexin-4 chr10 Not Cancer Driver No 1 hippie, biogrid 41 25 2 2 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 Census, Compendium Yes 1 hippie, biogrid 58 86 16 16 0
SLC3A2_ENST00000377890 SLC3A2 P08195 4F2 cell-surface antigen heavy chain chr11 Not Cancer Driver No 1 hippie 62 171 12 12 0
SLITRK2 SLITRK2 Q9H156 SLIT and NTRK-like protein 2 chrX Not Cancer Driver No 1 hippie 276 244 91 91 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 Not Cancer Driver No 1 hippie 38 248 7 7 7
SNRPF SNRPF P62306 Small nuclear ribonucleoprotein F chr12 Not Cancer Driver No 1 hippie, biogrid 4 10 0 0 0
SNX27 SNX27 Q96L92 Sorting nexin-27 chr1 Not Cancer Driver No 2 hippie, biogrid 65 120 9 9 0
SPNS3 SPNS3 Q6ZMD2 Protein spinster homolog 3 chr17 Not Cancer Driver No 1 hippie, biogrid 81 71 13 13 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 Census, Compendium Yes 1 hippie, biogrid 75 135 14 14 9
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 hippie 70 231 30 30 0
TATDN1 TATDN1 Q6P1N9 Deoxyribonuclease TATDN1 chr8 Not Cancer Driver No 1 hippie 25 0 0 0 0
TIMM10_ENST00000525587 TIMM10 P62072 Mitochondrial import inner membrane translocase subunit Tim10 chr11 Not Cancer Driver No 1 hippie, biogrid 6 43 6 6 0
TMEM131L_ENST00000409663 TMEM131L A2VDJ0 Transmembrane protein 131-like chr4 Not Cancer Driver No 1 hippie 188 448 47 47 0
TMEM176B_ENST00000429904 TMEM176B Q3YBM2 Transmembrane protein 176B chr7 Not Cancer Driver No 1 hippie, biogrid 62 33 8 8 0
TMEM237 TMEM237 Q96Q45 Transmembrane protein 237 chr2 Not Cancer Driver No 3 hippie, biogrid 47 177 19 19 0
TUBA1B TUBA1B P68363 Tubulin alpha-1B chain chr12 Not Cancer Driver No 1 hippie 41 52 9 9 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie 40 63 11 11 5
TUFM TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie 51 50 3 3 1
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 Not Cancer Driver No 1 hippie, biogrid 50 52 3 3 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 Not Cancer Driver No 2 hippie, biogrid 31 11 3 3 0
UGT3A2 UGT3A2 Q3SY77 UDP-glucuronosyltransferase 3A2 chr5 Not Cancer Driver No 1 hippie 169 0 0 0 0
USB1 USB1 Q9BQ65 U6 snRNA phosphodiesterase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 28 76 5 5 0
ZDHHC19 ZDHHC19 Q8WVZ1 Palmitoyltransferase ZDHHC19 chr3 Not Cancer Driver No 1 hippie, biogrid 48 35 10 10 0
ZNF202 ZNF202 O95125 Zinc finger protein 202 chr11 Not Cancer Driver No 1 hippie 89 357 58 58 0
ZNF491 ZNF491 Q8N8L2 Zinc finger protein 491 chr19 Not Cancer Driver No 1 hippie, biogrid 79 87 14 14 0
ZNF695 ZNF695 Q8IW36 Zinc finger protein 695 chr1 Not Cancer Driver No 1 hippie, biogrid 96 16 4 4 0