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PIAS3 ,PIAS3 ,Q9Y6X2
  • Uniprot Accession= Q9Y6X2
  • Ensembl Transcript= ENST00000393045.6
  • Uniprot Name= PIAS3
  • Name= E3 SUMO-protein ligase PIAS3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 82
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
APOE APOE P02649 Apolipoprotein E chr19 Not Cancer Driver No 1 hippie 25 124 6 6 12
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ATF7IP_ENST00000540793 ATF7IP Q6VMQ6 Activating transcription factor 7-interacting protein 1 chr12 Compendium Yes 1 hippie 160 1136 139 139 0
BCL11A BCL11A Q9H165 B-cell lymphoma/leukemia 11A chr2 Census, Compendium Yes 1 hippie 210 677 171 171 3
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 Not Cancer Driver No 1 hippie 45 190 19 19 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 65 456 42 42 5
CARHSP1_ENST00000611932 CARHSP1 Q9Y2V2 Calcium-regulated heat-stable protein 1 chr16 Not Cancer Driver No 1 hippie 17 104 14 14 0
CBS_ENST00000359624 CBS P35520 Cystathionine beta-synthase chr21 Not Cancer Driver No 1 hippie 61 160 19 19 103
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
CREM_ENST00000429130 CREM Q03060 cAMP-responsive element modulator chr10 Not Cancer Driver No 1 hippie 32 289 26 26 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 1 hippie 41 18 1 1 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 Census, Compendium Yes 1 hippie 428 323 116 116 2
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX Not Cancer Driver No 1 hippie 124 327 70 70 3
FOXP2_ENST00000350908 FOXP2 O15409 Forkhead box protein P2 chr7 Not Cancer Driver No 1 hippie 156 444 100 100 1
GEMIN4 GEMIN4 P57678 Gem-associated protein 4 chr17 Not Cancer Driver No 1 hippie 101 24 1 1 0
GFI1 GFI1 Q99684 Zinc finger protein Gfi-1 chr1 Not Cancer Driver No 1 hippie 57 199 29 29 2
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 Not Cancer Driver No 1 hippie 66 104 21 21 2
HABP4 HABP4 Q5JVS0 Intracellular hyaluronan-binding protein 4 chr9 Not Cancer Driver No 1 hippie 32 413 32 32 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 47 135 10 10 0
HIC1 HIC1 Q14526 Hypermethylated in cancer 1 protein chr17 Not Cancer Driver No 1 hippie 24 361 6 6 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 Census Yes 1 hippie 12 109 12 12 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 Not Cancer Driver No 1 hippie 75 302 59 59 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 Not Cancer Driver No 1 hippie 65 173 21 21 3
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 Not Cancer Driver No 1 hippie 30 1 0 0 0
MBD1_ENST00000591416 MBD1 Q9UIS9 Methyl-CpG-binding domain protein 1 chr18 Not Cancer Driver No 1 hippie 115 322 49 49 0
MITF_ENST00000448226 MITF O75030 Microphthalmia-associated transcription factor chr3 Census Yes 1 hippie 80 408 69 69 7
NCOA2 NCOA2 Q15596 Nuclear receptor coactivator 2 chr8 Census, Compendium Yes 1 hippie 210 1281 185 185 0
NR3C2_ENST00000344721 NR3C2 P08235 Mineralocorticoid receptor chr4 Not Cancer Driver No 1 hippie 168 484 88 88 14
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 Not Cancer Driver No 1 hippie 62 252 24 24 0
OPN1LW OPN1LW P04000 Long-wave-sensitive opsin 1 chrX Not Cancer Driver No 1 hippie 72 9 0 0 3
OTUB2 OTUB2 Q96DC9 Ubiquitin thioesterase OTUB2 chr14 Not Cancer Driver No 1 hippie 30 0 0 0 0
PGR PGR P06401 Progesterone receptor chr11 Not Cancer Driver No 1 hippie 161 480 55 55 0
PIM1 PIM1 P11309 Serine/threonine-protein kinase pim-1 chr6 Census, Compendium Yes 1 hippie 71 27 8 8 0
PLIN3 PLIN3 O60664 Perilipin-3 chr19 Not Cancer Driver No 1 hippie 44 256 34 34 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie 38 27 6 6 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 1 hippie 94 154 22 22 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PSMC1 PSMC1 P62191 26S proteasome regulatory subunit 4 chr14 Not Cancer Driver No 1 hippie 36 165 10 10 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 2 intact, hippie 75 400 48 48 0
REX1BD REX1BD Q96EN9 Required for excision 1-B domain-containing protein chr19 Not Cancer Driver No 1 hippie 6 61 1 1 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
SATB1_ENST00000454909 SATB1 Q01826 DNA-binding protein SATB1 chr3 Compendium Yes 1 hippie 130 482 84 84 12
SENP1 SENP1 Q9P0U3 Sentrin-specific protease 1 chr12 Not Cancer Driver No 1 hippie 64 355 44 44 0
SERBP1 SERBP1 Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein chr1 Not Cancer Driver No 1 hippie 53 408 53 53 0
SERPINA10 SERPINA10 Q9UK55 Protein Z-dependent protease inhibitor chr14 Not Cancer Driver No 1 hippie 108 74 18 18 0
SETDB1 SETDB1 Q15047 Histone-lysine N-methyltransferase SETDB1 chr1 Census, Compendium Yes 1 hippie 184 597 77 77 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 Not Cancer Driver No 1 hippie 35 28 2 2 5
SIAH2 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 Not Cancer Driver No 1 hippie 48 68 3 3 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 Not Cancer Driver No 1 hippie 70 435 31 31 0
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 Not Cancer Driver No 1 hippie 77 356 32 32 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 1 hippie 79 137 12 12 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 hippie 198 195 17 17 8
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 Not Cancer Driver No 1 hippie 38 248 7 7 7
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 Not Cancer Driver No 1 hippie 87 242 28 28 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 Not Cancer Driver No 1 hippie 52 52 9 9 0
SNIP1 SNIP1 Q8TAD8 Smad nuclear-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 58 285 40 40 1
SPOP SPOP O43791 Speckle-type POZ protein chr17 Census, Compendium Yes 1 hippie 147 25 5 5 6
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 Not Cancer Driver No 1 hippie 124 357 43 43 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
TAB2_ENST00000637181 TAB2 Q9NYJ8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 chr6 Not Cancer Driver No 1 hippie 87 573 73 73 2
TBP TBP P20226 TATA-box-binding protein chr6 Not Cancer Driver No 1 hippie 40 164 14 14 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 hippie 227 1632 190 190 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 hippie 59 87 11 11 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 Not Cancer Driver No 1 hippie 82 87 10 10 3
TRIM55 TRIM55 Q9BYV6 Tripartite motif-containing protein 55 chr8 Not Cancer Driver No 1 hippie 134 276 78 78 0
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 Not Cancer Driver No 1 hippie 47 71 13 13 0
TRIM8 TRIM8 Q9BZR9 E3 ubiquitin-protein ligase TRIM8 chr10 Not Cancer Driver No 1 hippie 60 209 29 29 0
UBA1 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX Not Cancer Driver No 1 hippie 117 165 22 22 6
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 hippie 26 77 9 9 2
ZFHX3_ENST00000268489 ZFHX3 Q15911 Zinc finger homeobox protein 3 chr16 Census, Compendium Yes 1 hippie 501 2555 337 337 0
ZMIZ1 ZMIZ1 Q9ULJ6 Zinc finger MIZ domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie 148 762 111 111 5
ZMIZ2_ENST00000441627 ZMIZ2 Q8NF64 Zinc finger MIZ domain-containing protein 2 chr7 Not Cancer Driver No 1 hippie 107 672 77 77 0