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PHLDA3 ,PHLDA3 ,Q9Y5J5
  • Uniprot Accession= Q9Y5J5
  • Ensembl Transcript= ENST00000367311.4
  • Uniprot Name= PHLDA3
  • Name= Pleckstrin homology-like domain family A member 3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 56
  • Number of Interaction partner in biogrid: 22
  • Number of Interaction partner in hippie: 98
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AHSA1 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 46 146 17 17 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARCN1 ARCN1 P48444 Coatomer subunit delta chr11 Not Cancer Driver No 1 hippie 46 194 24 24 0
ARL1 ARL1 P40616 ADP-ribosylation factor-like protein 1 chr12 Not Cancer Driver No 1 intact, hippie 17 4 0 0 0
ARMC6 ARMC6 Q6NXE6 Armadillo repeat-containing protein 6 chr19 Not Cancer Driver No 1 intact, hippie 65 77 5 5 0
ATP5MG ATP5MG O75964 ATP synthase subunit g, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 16 0 0 0 0
ATP6V1H_ENST00000396774 ATP6V1H Q9UI12 V-type proton ATPase subunit H chr8 Not Cancer Driver No 1 hippie 76 35 2 2 0
ATXN10 ATXN10 Q9UBB4 Ataxin-10 chr22 Not Cancer Driver No 1 hippie 46 37 2 2 0
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 Not Cancer Driver No 1 intact, hippie 153 840 87 87 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 Not Cancer Driver No 1 intact, hippie 102 528 62 62 0
CCDC47_ENST00000403162 CCDC47 Q96A33 PAT complex subunit CCDC47 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 49 265 23 23 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 24 0 0 0 0
CIAO2B CIAO2B Q9Y3D0 Cytosolic iron-sulfur assembly component 2B chr16 Not Cancer Driver No 1 intact, hippie 9 77 3 3 0
COPG2 COPG2 Q9UBF2 Coatomer subunit gamma-2 chr7 Not Cancer Driver No 1 hippie 36 59 3 3 0
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 intact, hippie 64 102 2 2 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 Census Yes 1 hippie 74 225 23 23 0
DNAAF5 DNAAF5 Q86Y56 Dynein axonemal assembly factor 5 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 89 81 0 0 1
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 50 152 21 21 0
DNAJB6 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 Not Cancer Driver No 1 hippie 33 198 17 17 3
DPM1_ENST00000371588 DPM1 O60762 Dolichol-phosphate mannosyltransferase subunit 1 chr20 Not Cancer Driver No 1 intact, hippie 38 29 6 6 3
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 intact, hippie 505 495 62 62 21
DYNLL1_ENST00000242577 DYNLL1 P63167 Dynein light chain 1, cytoplasmic chr12 Not Cancer Driver No 1 intact, hippie 9 0 0 0 0
DYNLRB1 DYNLRB1 Q9NP97 Dynein light chain roadblock-type 1 chr20 Not Cancer Driver No 1 intact, hippie 23 19 4 4 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 intact, hippie, biogrid 132 179 30 30 3
EHD4 EHD4 Q9H223 EH domain-containing protein 4 chr15 Not Cancer Driver No 1 hippie 54 98 7 7 0
FASTKD2_ENST00000402774 FASTKD2 Q9NYY8 FAST kinase domain-containing protein 2, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 74 30 2 2 0
FBXO44_ENST00000251547 FBXO44 Q9H4M3 F-box only protein 44 chr1 Not Cancer Driver No 1 hippie, biogrid 30 27 3 3 0
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 Not Cancer Driver No 1 hippie 32 31 3 3 0
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 Not Cancer Driver No 1 hippie 56 257 21 21 0
HLTF_ENST00000494055 HLTF Q14527 Helicase-like transcription factor chr3 Not Cancer Driver No 1 hippie 121 353 40 40 0
HNRNPM HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 intact, hippie, biogrid 108 463 67 67 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie, biogrid 149 251 52 52 0
IDH3B_ENST00000380843 IDH3B O43837 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial chr20 Not Cancer Driver No 1 hippie 32 49 3 3 1
IGBP1_ENST00000356413 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX Not Cancer Driver No 1 intact, hippie 51 193 28 28 0
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie 97 400 50 50 0
IPO11_ENST00000325324 IPO11 Q9UI26 Importin-11 chr5 Not Cancer Driver No 1 hippie 82 66 4 4 0
IPO4 IPO4 Q8TEX9 Importin-4 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 106 87 5 5 0
LBR_ENST00000272163 LBR Q14739 Delta(14)-sterol reductase LBR chr1 Not Cancer Driver No 1 hippie 95 130 15 15 5
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 131 18 2 2 1
MAPRE2 MAPRE2 Q15555 Microtubule-associated protein RP/EB family member 2 chr18 Not Cancer Driver No 1 intact, hippie 50 176 28 28 3
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 intact, hippie 88 109 20 20 1
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 Not Cancer Driver No 1 intact, hippie, biogrid 73 11 0 0 0
MRPS10 MRPS10 P82664 28S ribosomal protein S10, mitochondrial chr6 Not Cancer Driver No 1 intact, hippie 19 22 3 3 0
MRPS16 MRPS16 Q9Y3D3 28S ribosomal protein S16, mitochondrial chr10 Not Cancer Driver No 1 intact, hippie 7 29 2 2 0
MTHFD1L_ENST00000367321 MTHFD1L Q6UB35 Monofunctional C1-tetrahydrofolate synthase, mitochondrial chr6 Not Cancer Driver No 1 intact, hippie 117 139 11 11 0
MYO1A MYO1A Q9UBC5 Unconventional myosin-Ia chr12 Not Cancer Driver No 1 intact, hippie 170 57 5 5 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 Not Cancer Driver No 1 intact, hippie 110 66 11 11 0
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 Not Cancer Driver No 1 intact, hippie 126 61 6 6 0
NCAPG2_ENST00000356309 NCAPG2 Q86XI2 Condensin-2 complex subunit G2 chr7 Not Cancer Driver No 1 hippie 113 72 8 8 3
NDUFA6_ENST00000602404 NDUFA6 P56556 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 chr22 Not Cancer Driver No 1 hippie 10 14 2 2 1
NME3 NME3 Q13232 Nucleoside diphosphate kinase 3 chr16 Not Cancer Driver No 1 hippie 10 4 0 0 0
NOC2L NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 Not Cancer Driver No 1 hippie 77 281 31 31 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 intact, hippie 168 57 8 8 25
NUBP2 NUBP2 Q9Y5Y2 Cytosolic Fe-S cluster assembly factor NUBP2 chr16 Not Cancer Driver No 1 hippie 38 14 0 0 0
NUP205 NUP205 Q92621 Nuclear pore complex protein Nup205 chr7 Not Cancer Driver No 1 hippie, biogrid 251 101 16 16 1
NUP93 NUP93 Q8N1F7 Nuclear pore complex protein Nup93 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 97 158 23 23 3
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 Not Cancer Driver No 1 intact, hippie, biogrid 85 272 22 22 0
PDXDC1 PDXDC1 Q6P996 Pyridoxal-dependent decarboxylase domain-containing protein 1 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 95 272 29 29 0
PHLDA3 PHLDA3 Q9Y5J5 Pleckstrin homology-like domain family A member 3 chr1 Not Cancer Driver No 1 intact, hippie 20 0 0 0 0
POLR1C POLR1C O15160 DNA-directed RNA polymerases I and III subunit RPAC1 chr6 Not Cancer Driver No 1 hippie 34 28 3 3 13
PRPF6 PRPF6 O94906 Pre-mRNA-processing factor 6 chr20 Not Cancer Driver No 1 hippie 140 379 62 62 1
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 Not Cancer Driver No 1 intact 101 106 16 16 4
RAB5IF_ENST00000373852 RAB5IF Q9BUV8 Respirasome Complex Assembly Factor 1 chr20 Not Cancer Driver No 1 hippie 7 13 0 0 0
RARS2 RARS2 Q5T160 Probable arginine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 intact, hippie, biogrid 88 20 1 1 0
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 Not Cancer Driver No 1 hippie 45 39 6 6 0
RFC3 RFC3 P40938 Replication factor C subunit 3 chr13 Not Cancer Driver No 1 intact, hippie 31 13 1 1 0
RFXANK_ENST00000407360 RFXANK O14593 DNA-binding protein RFXANK chr19 Not Cancer Driver No 1 intact, hippie 22 120 6 6 1
RPL38_ENST00000439590 RPL38 P63173 60S ribosomal protein L38 chr17 Not Cancer Driver No 1 intact, hippie 2 9 0 0 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie 53 26 4 4 0
SAAL1 SAAL1 Q96ER3 Protein SAAL1 chr11 Not Cancer Driver No 1 hippie 46 75 11 11 0
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 Not Cancer Driver No 1 hippie 104 91 14 14 13
SEC63 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 intact, hippie 98 266 37 37 0
SF3B6 SF3B6 Q9Y3B4 Splicing factor 3B subunit 6 chr2 Not Cancer Driver No 1 intact, hippie 9 10 0 0 0
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 intact, hippie 31 29 1 1 0
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 110 21 7 7 2
SLC3A2_ENST00000377890 SLC3A2 P08195 4F2 cell-surface antigen heavy chain chr11 Not Cancer Driver No 1 hippie 62 171 12 12 0
SMAP1 SMAP1 Q8IYB5 Stromal membrane-associated protein 1 chr6 Not Cancer Driver No 1 hippie 54 352 46 46 0
SMC4_ENST00000344722 SMC4 Q9NTJ3 Structural maintenance of chromosomes protein 4 chr3 Not Cancer Driver No 1 intact, hippie 175 539 55 55 0
SNRPF SNRPF P62306 Small nuclear ribonucleoprotein F chr12 Not Cancer Driver No 1 intact, hippie 4 10 0 0 0
SRPRB SRPRB Q9Y5M8 Signal recognition particle receptor subunit beta chr3 Not Cancer Driver No 1 intact, hippie 30 23 3 3 0
SSR3_ENST00000265044 SSR3 Q9UNL2 Translocon-associated protein subunit gamma chr3 Not Cancer Driver No 1 hippie 30 18 5 5 0
SSR4_ENST00000370086 SSR4 P51571 Translocon-associated protein subunit delta chrX Not Cancer Driver No 1 hippie, biogrid 21 0 0 0 0
TFB2M TFB2M Q9H5Q4 Dimethyladenosine transferase 2, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 60 36 6 6 0
TMEM11 TMEM11 P17152 Transmembrane protein 11, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 23 8 1 1 0
TMEM33_ENST00000325094 TMEM33 P57088 Transmembrane protein 33 chr4 Not Cancer Driver No 1 hippie 24 6 0 0 0
TNPO3 TNPO3 Q9Y5L0 Transportin-3 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 122 12 1 1 1
TOMM22 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 intact, hippie 18 83 9 9 0
TRIO TRIO O75962 Triple functional domain protein chr5 Not Cancer Driver No 1 hippie 400 1052 118 118 10
TTC27 TTC27 Q6P3X3 Tetratricopeptide repeat protein 27 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 109 40 5 5 0
TUBGCP4 TUBGCP4 Q9UGJ1 Gamma-tubulin complex component 4 chr15 Not Cancer Driver No 1 hippie 79 62 5 5 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 intact, hippie 109 141 24 24 0
UNC45A UNC45A Q9H3U1 Protein unc-45 homolog A chr15 Not Cancer Driver No 1 hippie 78 128 4 4 0
UQCC3_ENST00000377953 UQCC3 Q6UW78 Ubiquinol-cytochrome-c reductase complex assembly factor 3 chr11 Not Cancer Driver No 1 intact, hippie 11 54 9 9 1
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX Not Cancer Driver No 1 hippie 38 4 1 1 0
WWC3 WWC3 Q9ULE0 Protein WWC3 chrX Not Cancer Driver No 1 intact, hippie 214 638 114 114 0
XPO4 XPO4 Q9C0E2 Exportin-4 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 124 66 5 5 0
XPO5 XPO5 Q9HAV4 Exportin-5 chr6 Not Cancer Driver No 1 hippie, biogrid 112 64 7 7 0
ZW10 ZW10 O43264 Centromere/kinetochore protein zw10 homolog chr11 Not Cancer Driver No 1 intact, hippie, biogrid 90 63 11 11 0