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PHC2 ,PHC2 ,Q8IXK0
  • Uniprot Accession= Q8IXK0
  • Ensembl Transcript= ENST00000257118.5
  • Uniprot Name= PHC2
  • Name= Polyhomeotic-like protein 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 10
  • Number of Interaction partner in biogrid: 38
  • Number of Interaction partner in hippie: 121
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AEN AEN Q8WTP8 Apoptosis-enhancing nuclease chr15 Not Cancer Driver No 1 hippie 39 183 21 21 0
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 Not Cancer Driver No 1 hippie, biogrid 72 162 10 10 22
AGRN AGRN O00468 Agrin chr1 Not Cancer Driver No 1 hippie 188 490 40 40 5
AL662899.2_ENST00000375880 CSNK2B Q5SRQ3 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 21 30 1 1 0
AP1M1_ENST00000291439 AP1M1 Q9BXS5 AP-1 complex subunit mu-1 chr19 Not Cancer Driver No 1 hippie 64 38 12 12 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BCOR BCOR Q6W2J9 BCL-6 corepressor chrX Census, Compendium Yes 1 hippie, biogrid 291 1285 226 226 1
BCORL1_ENST00000218147 BCORL1 Q5H9F3-1 Isoform 1 of BCL-6 corepressor-like protein 1 chrX Census, Compendium Yes 1 hippie, biogrid 264 1365 212 212 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 3 hippie, biogrid 50 150 30 30 0
BRD3 BRD3 Q15059 Bromodomain-containing protein 3 chr9 Census Yes 1 hippie 87 566 68 68 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BSDC1_ENST00000455895 BSDC1 Q9NW68 BSD domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 45 283 32 32 0
BYSL BYSL Q13895 Bystin chr6 Not Cancer Driver No 1 hippie 38 176 14 14 0
C1orf109 C1orf109 Q9NX04 Uncharacterized protein C1orf109 chr1 Not Cancer Driver No 1 hippie 17 0 0 0 0
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 Not Cancer Driver No 1 hippie 72 225 35 35 11
CBX2 CBX2 Q14781 Chromobox protein homolog 2 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 56 487 53 53 2
CBX4 CBX4 O00257 E3 SUMO-protein ligase CBX4 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 72 477 63 63 0
CBX6 CBX6 O95503 Chromobox protein homolog 6 chr22 Not Cancer Driver No 3 intact, hippie, biogrid 57 335 54 54 0
CBX7 CBX7 O95931 Chromobox protein homolog 7 chr22 Not Cancer Driver No 5 intact, hippie, biogrid 40 175 34 34 0
CBX8 CBX8 Q9HC52 Chromobox protein homolog 8 chr17 Not Cancer Driver No 2 hippie, biogrid 59 309 51 51 0
CENPA CENPA P49450 Histone H3-like centromeric protein A chr2 Not Cancer Driver No 1 hippie, biogrid 15 50 4 4 0
COL26A1 COL26A1 Q96A83 Collagen alpha-1(XXVI) chain chr7 Not Cancer Driver No 1 hippie 71 306 49 49 0
CPVL_ENST00000265394 CPVL Q9H3G5 Probable serine carboxypeptidase CPVL chr7 Not Cancer Driver No 1 hippie 81 0 0 0 0
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CRKL CRKL P46109 Crk-like protein chr22 Not Cancer Driver No 1 hippie 38 160 25 25 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 20 19 0 0 4
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie 203 702 78 78 4
DRG1 DRG1 Q9Y295 Developmentally-regulated GTP-binding protein 1 chr22 Not Cancer Driver No 1 hippie 35 31 0 0 0
EED_ENST00000263360 EED O75530 Polycomb protein EED chr11 Census Yes 1 hippie 64 79 11 11 6
ENKD1 ENKD1 Q9H0I2 Enkurin domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 40 307 34 34 0
EPC1 EPC1 Q9H2F5 Enhancer of polycomb homolog 1 chr10 Not Cancer Driver No 1 biogrid 104 515 68 68 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
FAM124A_ENST00000322475 FAM124A Q86V42 Protein FAM124A chr13 Not Cancer Driver No 1 hippie 69 357 39 39 0
FAM13C FAM13C Q8NE31 Protein FAM13C chr10 Not Cancer Driver No 1 hippie 139 527 128 128 0
FAM161A_ENST00000405894 FAM161A Q3B820 Protein FAM161A chr2 Not Cancer Driver No 1 hippie 102 510 83 83 0
FBLN5 FBLN5 Q9UBX5 Fibulin-5 chr14 Not Cancer Driver No 1 hippie, biogrid 77 11 2 2 16
FBRS_ENST00000287468 FBRS Q9HAH7 Probable fibrosin-1 chr16 Not Cancer Driver No 1 hippie, biogrid 32 407 27 27 0
FHL3 FHL3 Q13643 Four and a half LIM domains protein 3 chr1 Not Cancer Driver No 1 hippie 33 0 0 0 0
FOSB FOSB P53539 Protein FosB chr19 Not Cancer Driver No 1 hippie 50 313 44 44 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 hippie 88 312 53 53 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 1 hippie 68 388 42 42 0
GFI1B GFI1B Q5VTD9 Zinc finger protein Gfi-1b chr9 Not Cancer Driver No 1 hippie 50 142 23 23 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 Not Cancer Driver No 1 intact, hippie 91 570 50 50 0
HECW2_ENST00000644256 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 348 845 195 195 4
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 Not Cancer Driver No 1 hippie 65 173 21 21 3
KBTBD7 KBTBD7 Q8WVZ9 Kelch repeat and BTB domain-containing protein 7 chr13 Not Cancer Driver No 1 hippie 92 105 6 6 0
KCTD17 KCTD17 Q8N5Z5 BTB/POZ domain-containing protein KCTD17 chr22 Not Cancer Driver No 1 hippie, biogrid 23 187 14 14 1
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie 67 291 28 28 3
KDM2B KDM2B Q8NHM5 Lysine-specific demethylase 2B chr12 Not Cancer Driver No 1 hippie, biogrid 187 617 90 90 0
KIFC3_ENST00000379655 KIFC3 Q9BVG8 Kinesin-like protein KIFC3 chr16 Not Cancer Driver No 1 hippie 84 487 42 42 0
KLF11 KLF11 O14901 Krueppel-like factor 11 chr2 Not Cancer Driver No 1 hippie 57 308 38 38 2
KLHDC7B KLHDC7B Q96G42 Kelch domain-containing protein 7B chr22 Not Cancer Driver No 1 intact, hippie 70 256 13 13 0
KMO KMO O15229 Kynurenine 3-monooxygenase chr1 Not Cancer Driver No 1 hippie, biogrid 77 0 0 0 0
KRT31 KRT31 Q15323 Keratin, type I cuticular Ha1 chr17 Not Cancer Driver No 1 hippie 116 64 16 16 0
L3MBTL3_ENST00000368136 L3MBTL3 Q96JM7 Lethal(3)malignant brain tumor-like protein 3 chr6 Not Cancer Driver No 1 hippie 117 351 59 59 0
LMO1 LMO1 P25800 Rhombotin-1 chr11 Census Yes 1 hippie 23 0 0 0 0
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 Census Yes 1 hippie 35 14 1 1 0
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 Not Cancer Driver No 1 hippie 30 1 0 0 0
MAB21L3 MAB21L3 Q8N8X9 Protein mab-21-like 3 chr1 Not Cancer Driver No 1 hippie 40 0 0 0 0
MAGEB6 MAGEB6 Q8N7X4 Melanoma-associated antigen B6 chrX Not Cancer Driver No 1 hippie 179 184 81 81 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 39 25 1 1 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 Not Cancer Driver No 1 hippie 43 92 5 5 0
MAPKAPK3 MAPKAPK3 Q16644 MAP kinase-activated protein kinase 3 chr3 Not Cancer Driver No 1 hippie 35 117 12 12 1
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie, biogrid 104 275 38 38 1
MCRS1_ENST00000550165 MCRS1 Q96EZ8 Microspherule protein 1 chr12 Not Cancer Driver No 1 hippie 72 151 18 18 0
MED14 MED14 O60244 Mediator of RNA polymerase II transcription subunit 14 chrX Not Cancer Driver No 1 biogrid 182 318 45 45 0
MFAP1 MFAP1 P55081 Microfibrillar-associated protein 1 chr15 Not Cancer Driver No 1 hippie 58 377 53 53 0
MORF4L2_ENST00000433176 MORF4L2 Q15014 Mortality factor 4-like protein 2 chrX Not Cancer Driver No 1 hippie 44 136 21 21 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 hippie 48 111 17 17 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
PCGF1 PCGF1 Q9BSM1 Polycomb group RING finger protein 1 chr2 Not Cancer Driver No 2 hippie, biogrid 28 8 0 0 0
PCGF3 PCGF3 Q3KNV8 Polycomb group RING finger protein 3 chr4 Not Cancer Driver No 2 hippie, biogrid 38 47 11 11 0
PCGF5 PCGF5 Q86SE9 Polycomb group RING finger protein 5 chr10 Not Cancer Driver No 2 hippie, biogrid 31 52 5 5 0
PCGF6 PCGF6 Q9BYE7 Polycomb group RING finger protein 6 chr10 Not Cancer Driver No 1 hippie, biogrid 29 142 11 11 0
PHC1_ENST00000544916 PHC1 P78364 Polyhomeotic-like protein 1 chr12 Not Cancer Driver No 4 hippie, biogrid 82 851 69 69 1
PHC2 PHC2 Q8IXK0 Polyhomeotic-like protein 2 chr1 Not Cancer Driver No 1 hippie 101 674 67 67 0
PHC3_ENST00000494943 PHC3 Q8NDX5 Polyhomeotic-like protein 3 chr3 Not Cancer Driver No 2 hippie, biogrid 102 795 85 85 0
PLAGL2 PLAGL2 Q9UPG8 Zinc finger protein PLAGL2 chr20 Not Cancer Driver No 1 intact, hippie 62 204 29 29 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
POLR2L POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 Not Cancer Driver No 1 hippie 10 0 0 0 0
PPP1R16B PPP1R16B Q96T49 Protein phosphatase 1 regulatory inhibitor subunit 16B chr20 Not Cancer Driver No 1 hippie 132 220 66 66 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 72 124 17 17 0
PRPF3 PRPF3 O43395 U4/U6 small nuclear ribonucleoprotein Prp3 chr1 Not Cancer Driver No 1 hippie 97 523 75 75 2
PRPF31 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie 58 213 17 17 2
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RING1 RING1 Q06587 E3 ubiquitin-protein ligase RING1 chr6 Not Cancer Driver No 2 hippie, biogrid 60 302 44 44 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 2 hippie, biogrid 40 203 22 22 0
RPL4 RPL4 P36578 60S ribosomal protein L4 chr15 Not Cancer Driver No 1 hippie, biogrid 49 222 31 31 0
RPL7 RPL7 P18124 60S ribosomal protein L7 chr8 Not Cancer Driver No 3 intact, hippie, biogrid 24 40 4 4 0
RWDD2B RWDD2B P57060 RWD domain-containing protein 2B chr21 Not Cancer Driver No 1 hippie 38 41 0 0 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie, biogrid 37 214 37 37 0
SCMH1 SCMH1 Q96GD3 Polycomb protein SCMH1 chr1 Not Cancer Driver No 2 hippie, biogrid 64 285 21 21 0
SCML1 SCML1 Q9UN30 Sex comb on midleg-like protein 1 chrX Not Cancer Driver No 1 hippie 44 130 19 19 0
SCML2 SCML2 Q9UQR0 Sex comb on midleg-like protein 2 chrX Not Cancer Driver No 1 hippie 118 411 67 67 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 Not Cancer Driver No 1 hippie 39 17 2 2 0
SFMBT1 SFMBT1 Q9UHJ3 Scm-like with four MBT domains protein 1 chr3 Not Cancer Driver No 1 hippie 93 201 26 26 0
SFTPC SFTPC P11686 Pulmonary surfactant-associated protein C chr8 Not Cancer Driver No 2 hippie, biogrid 21 19 2 2 5
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 Not Cancer Driver No 1 hippie 35 28 2 2 5
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SORT1 SORT1 Q99523 Sortilin chr1 Not Cancer Driver No 1 intact, hippie 69 110 2 2 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 Not Cancer Driver No 1 intact, hippie 30 179 11 11 0
SRCAP SRCAP Q6ZRS2 Helicase SRCAP chr16 Not Cancer Driver No 1 biogrid 438 2534 340 340 0
SSX2IP SSX2IP Q9Y2D8 Afadin- and alpha-actinin-binding protein chr1 Not Cancer Driver No 1 hippie 82 265 31 31 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 Not Cancer Driver No 1 hippie 93 285 39 39 0
SYT16 SYT16 Q17RD7 Synaptotagmin-16 chr14 Not Cancer Driver No 1 hippie 178 394 113 113 0
TAB1 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 1 hippie 81 232 34 34 0
THAP3 THAP3 Q8WTV1 THAP domain-containing protein 3 chr1 Not Cancer Driver No 1 biogrid 35 181 27 27 0
THAP7_ENST00000399133 THAP7 Q9BT49 THAP domain-containing protein 7 chr22 Not Cancer Driver No 1 hippie 34 214 24 24 0
TMEM70 TMEM70 Q9BUB7 Transmembrane protein 70, mitochondrial chr8 Not Cancer Driver No 1 hippie 26 24 4 4 1
TRIM41 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 Not Cancer Driver No 1 hippie 69 385 38 38 0
TRIM55 TRIM55 Q9BYV6 Tripartite motif-containing protein 55 chr8 Not Cancer Driver No 1 hippie, biogrid 134 276 78 78 0
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 Not Cancer Driver No 1 hippie, biogrid 47 71 13 13 0
TUBA1C_ENST00000301072 TUBA1C Q9BQE3 Tubulin alpha-1C chain chr12 Not Cancer Driver No 1 hippie 39 50 5 5 0
YAF2_ENST00000534854 YAF2 Q8IY57 YY1-associated factor 2 chr12 Not Cancer Driver No 1 hippie, biogrid 27 166 27 27 0
ZBTB24 ZBTB24 O43167 Zinc finger and BTB domain-containing protein 24 chr6 Not Cancer Driver No 1 hippie 71 383 43 43 1
ZGPAT ZGPAT Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein chr20 Not Cancer Driver No 1 hippie 75 346 49 49 0
ZMAT2 ZMAT2 Q96NC0 Zinc finger matrin-type protein 2 chr5 Not Cancer Driver No 1 hippie 24 148 19 19 0
ZNF417 ZNF417 Q8TAU3 Zinc finger protein 417 chr19 Not Cancer Driver No 1 hippie 76 156 23 23 0
ZNF691 ZNF691 Q5VV52 Zinc finger protein 691 chr1 Not Cancer Driver No 1 hippie, biogrid 34 193 22 22 0