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PFKFB2 ,PFKFB2 ,O60825
  • Uniprot Accession= O60825
  • Ensembl Transcript= ENST00000367080.7
  • Uniprot Name= PFKFB2
  • Name= 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 14
  • Number of Interaction partner in hippie: 49
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
CBY1_ENST00000216029 CBY1 Q9Y3M2 Protein chibby homolog 1 chr22 Not Cancer Driver No 1 hippie 13 98 11 11 0
COPS2_ENST00000388901 COPS2 P61201 COP9 signalosome complex subunit 2 chr15 Not Cancer Driver No 1 hippie, biogrid 59 59 9 9 0
CPSF7_ENST00000394888 CPSF7 Q8N684 Cleavage and polyadenylation specificity factor subunit 7 chr11 Not Cancer Driver No 1 hippie 55 398 52 52 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
CUL9 CUL9 Q8IWT3 Cullin-9 chr6 Not Cancer Driver No 1 hippie 321 633 73 73 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 Not Cancer Driver No 1 hippie 321 312 60 60 1
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
FAM83B FAM83B Q5T0W9 Protein FAM83B chr6 Not Cancer Driver No 1 hippie 314 684 219 219 0
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 Not Cancer Driver No 1 hippie 88 73 14 14 107
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
MOB2_ENST00000614710 MOB2 Q70IA6 MOB kinase activator 2 chr11 Not Cancer Driver No 1 hippie, biogrid 22 46 0 0 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 Census, Compendium Yes 1 hippie 191 552 76 76 0
PAGE4_ENST00000376141 PAGE4 O60829 P antigen family member 4 chrX Not Cancer Driver No 1 hippie 20 102 20 20 0
PARVB_ENST00000338758 PARVB Q9HBI1 Beta-parvin chr22 Not Cancer Driver No 1 hippie, biogrid 45 83 9 9 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 Not Cancer Driver No 1 hippie 86 464 54 54 12
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 Not Cancer Driver No 1 hippie 68 97 18 18 0
PFKFB3_ENST00000379775 PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 chr10 Not Cancer Driver No 2 hippie, biogrid 65 97 19 19 0
PFKFB4 PFKFB4 Q16877 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 chr3 Not Cancer Driver No 1 hippie, biogrid 71 44 3 3 0
PGAP2_ENST00000463452 PGAP2 Q9UHJ9 Post-GPI attachment to proteins factor 2 chr11 Not Cancer Driver No 1 hippie 38 0 0 0 5
POLDIP3_ENST00000252115 POLDIP3 Q9BY77 Polymerase delta-interacting protein 3 chr22 Not Cancer Driver No 1 hippie 39 301 29 29 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 72 124 17 17 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 Not Cancer Driver No 1 hippie 128 98 26 26 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 1 hippie 94 154 22 22 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
RAB3IP RAB3IP Q96QF0 Rab-3A-interacting protein chr12 Not Cancer Driver No 1 hippie 85 227 33 33 0
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 Census, Compendium Yes 1 hippie 118 686 91 91 0
RMDN3 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie 45 196 17 17 0
SARNP SARNP P82979 SAP domain-containing ribonucleoprotein chr12 Not Cancer Driver No 1 hippie 27 195 27 27 0
SCYL2_ENST00000360820 SCYL2 Q6P3W7 SCY1-like protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 103 328 29 29 0
SH2D3A SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 Not Cancer Driver No 1 hippie, biogrid 68 305 40 40 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 hippie 198 195 17 17 8
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 Not Cancer Driver No 1 biogrid 89 256 31 31 0
SPSB4 SPSB4 Q96A44 SPRY domain-containing SOCS box protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 42 75 3 3 0
SRRM2 SRRM2 Q9UQ35 Serine/arginine repetitive matrix protein 2 chr16 Not Cancer Driver No 1 hippie 433 2748 431 431 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 Not Cancer Driver No 1 hippie 85 49 7 7 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 2 hippie, biogrid 22 109 4 4 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 hippie, biogrid 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 2 hippie, biogrid 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 2 hippie, biogrid 30 81 10 10 0
ZC3H11A_ENST00000332127 ZC3H11A O75152 Zinc finger CCCH domain-containing protein 11A chr1 Not Cancer Driver No 1 hippie 96 693 79 79 0
ZCCHC17_ENST00000373714 ZCCHC17 Q9NP64 Zinc finger CCHC domain-containing protein 17 chr1 Not Cancer Driver No 1 hippie 25 153 16 16 0