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PDZK1_ENST00000344770 ,PDZK1 ,Q5T2W1
  • Uniprot Accession= Q5T2W1
  • Ensembl Transcript= ENST00000344770.6
  • Uniprot Name= PDZK1
  • Name= Na(+)/H(+) exchange regulatory cofactor NHE-RF3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 6
  • Number of Interaction partner in biogrid: 29
  • Number of Interaction partner in hippie: 75
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 Not Cancer Driver No 1 hippie 284 245 40 40 31
ABCC2 ABCC2 Q92887 ATP-binding cassette sub-family C member 2 chr10 Not Cancer Driver No 1 hippie 202 102 23 23 4
ABCC4_ENST00000376887 ABCC4 O15439 ATP-binding cassette sub-family C member 4 chr13 Not Cancer Driver No 3 hippie, biogrid 174 97 6 6 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX Not Cancer Driver No 3 intact, hippie 104 68 5 5 0
AKAP10 AKAP10 O43572 A-kinase anchor protein 10, mitochondrial chr17 Not Cancer Driver No 1 hippie 51 304 16 16 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARHGAP17 ARHGAP17 Q68EM7 Rho GTPase-activating protein 17 chr16 Not Cancer Driver No 2 hippie, biogrid 123 547 72 72 0
ASNSD1 ASNSD1 Q9NWL6 Asparagine synthetase domain-containing protein 1 chr2 Not Cancer Driver No 2 hippie, biogrid 83 42 9 9 0
BCR BCR P11274 Breakpoint cluster region protein chr22 Census, Compendium Yes 3 hippie, biogrid 146 603 69 69 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie 52 214 31 31 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 Not Cancer Driver No 2 hippie, biogrid 73 95 12 12 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 2 intact, hippie 287 145 18 18 151
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 Not Cancer Driver No 1 hippie 105 88 7 7 0
COLEC12 COLEC12 Q5KU26 Collectin-12 chr18 Not Cancer Driver No 1 hippie, biogrid 147 450 90 90 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 Not Cancer Driver No 1 hippie 75 0 0 0 0
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 Not Cancer Driver No 2 hippie, biogrid 43 13 1 1 0
CYSLTR2_ENST00000614739 CYSLTR2 Q9NS75 Cysteinyl leukotriene receptor 2 chr13 Census, Compendium Yes 1 intact, hippie 64 0 0 0 0
DECR2 DECR2 Q9NUI1 Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] chr16 Not Cancer Driver No 2 hippie, biogrid 44 36 2 2 0
ECI2 ECI2 O75521 Enoyl-CoA delta isomerase 2 chr6 Not Cancer Driver No 2 hippie, biogrid 52 70 8 8 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
FARP2 FARP2 O94887 FERM, ARHGEF and pleckstrin domain-containing protein 2 chr2 Not Cancer Driver No 1 hippie 133 250 39 39 0
FRYL FRYL O94915 Protein furry homolog-like chr4 Not Cancer Driver No 2 hippie, biogrid 366 666 79 79 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 1 intact, hippie 65 288 42 42 62
GPR17 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 Not Cancer Driver No 1 hippie 57 16 4 4 0
GUCY2C GUCY2C P25092 Guanylyl cyclase C chr12 Not Cancer Driver No 1 intact, hippie 209 51 7 7 2
KCTD17 KCTD17 Q8N5Z5 BTB/POZ domain-containing protein KCTD17 chr22 Not Cancer Driver No 2 hippie, biogrid 23 187 14 14 1
KCTD2 KCTD2 Q14681 BTB/POZ domain-containing protein KCTD2 chr17 Not Cancer Driver No 2 hippie, biogrid 34 128 11 11 0
KCTD3 KCTD3 Q9Y597 BTB/POZ domain-containing protein KCTD3 chr1 Not Cancer Driver No 2 hippie, biogrid 113 324 45 45 0
KCTD5 KCTD5 Q9NXV2 BTB/POZ domain-containing protein KCTD5 chr16 Not Cancer Driver No 2 hippie, biogrid 22 32 3 3 0
KLHL17 KLHL17 Q6TDP4 Kelch-like protein 17 chr1 Not Cancer Driver No 2 hippie, biogrid 60 135 5 5 0
KLHL24_ENST00000242810 KLHL24 Q6TFL4 Kelch-like protein 24 chr3 Not Cancer Driver No 2 hippie, biogrid 102 17 6 6 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
NDUFV2 NDUFV2 P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial chr18 Not Cancer Driver No 1 hippie 40 69 15 15 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 Not Cancer Driver No 1 hippie 168 347 38 38 0
OTULIN OTULIN Q96BN8 Ubiquitin thioesterase otulin chr5 Not Cancer Driver No 2 hippie, biogrid 47 97 5 5 2
PDZK1IP1_ENST00000371885 PDZK1IP1 Q13113 PDZK1-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 22 21 0 0 0
PEX5_ENST00000420616 PEX5 P50542 Peroxisomal targeting signal 1 receptor chr12 Not Cancer Driver No 1 hippie 73 321 36 36 2
PIGL PIGL Q9Y2B2 N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase chr17 Not Cancer Driver No 1 hippie 27 4 0 0 1
PTGIR PTGIR P43119 Prostacyclin receptor chr19 Not Cancer Driver No 1 hippie 40 47 4 4 0
PUS3_ENST00000530811 PUS3 Q9BZE2 tRNA pseudouridine(38/39) synthase chr11 Not Cancer Driver No 1 hippie 55 150 15 15 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 Not Cancer Driver No 1 hippie 94 178 32 32 0
SCARB1_ENST00000415380 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 Not Cancer Driver No 3 hippie, biogrid 53 6 1 1 0
SDK2 SDK2 Q58EX2 Protein sidekick-2 chr17 Not Cancer Driver No 1 hippie 330 850 131 131 0
SH2D5 SH2D5 Q6ZV89 SH2 domain-containing protein 5 chr1 Not Cancer Driver No 2 hippie, biogrid 50 87 14 14 0
SHKBP1 SHKBP1 Q8TBC3 SH3KBP1-binding protein 1 chr19 Not Cancer Driver No 2 hippie, biogrid 93 281 32 32 0
SLC13A1 SLC13A1 Q9BZW2 Solute carrier family 13 member 1 chr7 Not Cancer Driver No 1 hippie 146 39 6 6 0
SLC15A2 SLC15A2 Q16348 Solute carrier family 15 member 2 chr3 Not Cancer Driver No 1 hippie 153 37 7 7 0
SLC15A5 SLC15A5 A6NIM6 Solute carrier family 15 member 5 chr12 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
SLC17A1_ENST00000476801 SLC17A1 Q14916 Sodium-dependent phosphate transport protein 1 chr6 Not Cancer Driver No 1 hippie 84 7 2 2 0
SLC19A3 SLC19A3 Q9BZV2 Thiamine transporter 2 chr2 Not Cancer Driver No 2 hippie, biogrid 74 48 4 4 2
SLC1A3 SLC1A3 P43003 Excitatory amino acid transporter 1 chr5 Not Cancer Driver No 2 hippie, biogrid 100 55 9 9 1
SLC22A11 SLC22A11 Q9NSA0 Solute carrier family 22 member 11 chr11 Not Cancer Driver No 1 hippie 85 41 7 7 0
SLC22A12 SLC22A12 Q96S37 Solute carrier family 22 member 12 chr11 Not Cancer Driver No 1 hippie 93 10 3 3 10
SLC22A4 SLC22A4 Q9H015 Solute carrier family 22 member 4 chr5 Not Cancer Driver No 1 hippie 57 8 2 2 0
SLC22A5_ENST00000245407 SLC22A5 O76082 Solute carrier family 22 member 5 chr5 Not Cancer Driver No 3 hippie, biogrid 53 15 2 2 73
SLC26A6 SLC26A6 Q9BXS9 Solute carrier family 26 member 6 chr3 Not Cancer Driver No 1 hippie 68 87 13 13 0
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 Not Cancer Driver No 1 hippie 92 46 8 8 9
SLC34A3_ENST00000361134 SLC34A3 Q8N130 Sodium-dependent phosphate transport protein 2C chr9 Not Cancer Driver No 1 hippie 56 63 9 9 6
SLC4A7_ENST00000295736 SLC4A7 Q9Y6M7 Sodium bicarbonate cotransporter 3 chr3 Not Cancer Driver No 2 hippie, biogrid 165 406 57 57 0
SLC5A6 SLC5A6 Q9Y289 Sodium-dependent multivitamin transporter chr2 Not Cancer Driver No 2 hippie, biogrid 87 28 0 0 2
SLC6A6_ENST00000622186 SLC6A6 P31641 Sodium- and chloride-dependent taurine transporter chr3 Not Cancer Driver No 2 hippie, biogrid 80 22 1 1 2
SLC9A3 SLC9A3 P48764 Sodium/hydrogen exchanger 3 chr5 Not Cancer Driver No 1 hippie 105 225 30 30 3
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 Not Cancer Driver No 1 hippie 19 318 16 16 4
SLC9A3R2 SLC9A3R2 Q15599 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 chr16 Not Cancer Driver No 1 hippie 26 328 26 26 0
SLCO1A2 SLCO1A2 P46721 Solute carrier organic anion transporter family member 1A2 chr12 Not Cancer Driver No 1 hippie 155 30 4 4 0
SLK SLK Q9H2G2 STE20-like serine/threonine-protein kinase chr10 Not Cancer Driver No 1 hippie 134 962 96 96 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 Not Cancer Driver No 1 hippie 47 25 2 2 0
SSTR5 SSTR5 P35346 Somatostatin receptor type 5 chr16 Not Cancer Driver No 1 hippie 60 45 12 12 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
USP3 USP3 Q9Y6I4 Ubiquitin carboxyl-terminal hydrolase 3 chr15 Not Cancer Driver No 2 hippie, biogrid 60 45 4 4 0
ZBED1 ZBED1 O96006 E3 SUMO-protein ligase ZBED1 chrX Not Cancer Driver No 2 hippie, biogrid 137 97 12 12 0
ZBTB5 ZBTB5 O15062 Zinc finger and BTB domain-containing protein 5 chr9 Not Cancer Driver No 2 hippie, biogrid 79 439 56 56 0