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PDE4B ,PDE4B ,Q07343
  • Uniprot Accession= Q07343
  • Ensembl Transcript= ENST00000329654.8
  • Uniprot Name= PDE4B
  • Name= cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 5
  • Number of Interaction partner in biogrid: 3
  • Number of Interaction partner in hippie: 64
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 Not Cancer Driver No 1 hippie 131 244 42 42 8
ALB ALB P02768 Albumin chr4 Compendium Yes 1 hippie 162 6 0 0 3
ANXA6 ANXA6 P08133 Annexin A6 chr5 Not Cancer Driver No 1 hippie 95 107 15 15 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 Not Cancer Driver No 1 intact, hippie 28 131 8 8 3
ARCN1 ARCN1 P48444 Coatomer subunit delta chr11 Not Cancer Driver No 1 hippie 46 194 24 24 0
CALR CALR P27797 Calreticulin chr19 Census Yes 1 hippie 45 245 31 31 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie 37 19 0 0 0
CDK11B CDK11B P21127 Cyclin-dependent kinase 11B chr1 Not Cancer Driver No 1 hippie 74 501 35 35 0
CFL2_ENST00000341223 CFL2 Q9Y281 Cofilin-2 chr14 Not Cancer Driver No 1 hippie 25 0 0 0 1
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 3 intact, hippie, biogrid 132 514 82 82 0
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie 51 21 2 2 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 hippie 416 1456 214 214 28
FUS FUS P35637 RNA-binding protein FUS chr16 Census Yes 1 hippie 51 524 51 51 20
G3BP2_ENST00000395719 G3BP2 Q9UN86 Ras GTPase-activating protein-binding protein 2 chr4 Not Cancer Driver No 1 hippie 64 384 53 53 0
GSN GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 hippie 76 316 28 28 2
HBB HBB P68871 Hemoglobin subunit beta chr11 Not Cancer Driver No 1 hippie 45 7 2 2 5
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 61 82 6 6 2
IFRD1_ENST00000005558 IFRD1 O00458 Interferon-related developmental regulator 1 chr7 Not Cancer Driver No 1 hippie 60 87 10 10 0
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie 97 400 50 50 0
KRT18_ENST00000388837 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 Not Cancer Driver No 1 hippie 57 179 21 21 4
KRT6B KRT6B P04259 Keratin, type II cytoskeletal 6B chr12 Not Cancer Driver No 1 hippie 121 162 39 39 1
LCP1 LCP1 P13796 Plastin-2 chr13 Census Yes 1 hippie 99 73 11 11 0
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 Not Cancer Driver No 1 hippie 50 249 31 31 0
MAGEA11 MAGEA11 P43364 Melanoma-associated antigen 11 chrX Not Cancer Driver No 1 intact, hippie 115 217 49 49 0
MID1 MID1 O15344 E3 ubiquitin-protein ligase Midline-1 chrX Not Cancer Driver No 1 hippie 86 86 16 16 4
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MPRIP_ENST00000341712 MPRIP Q6WCQ1 Myosin phosphatase Rho-interacting protein chr17 Not Cancer Driver No 1 hippie 118 735 95 95 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 Census Yes 1 hippie 92 37 4 4 70
MYH14_ENST00000596571 MYH14 Q7Z406 Myosin-14 chr19 Not Cancer Driver No 1 hippie 275 1215 169 169 5
MYO1E MYO1E Q12965 Unconventional myosin-Ie chr15 Not Cancer Driver No 1 hippie 137 229 14 14 1
MYO5A MYO5A Q9Y4I1 Unconventional myosin-Va chr15 Census, Compendium Yes 1 hippie 224 497 58 58 0
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX Census, Compendium Yes 1 hippie 101 349 64 64 0
NPAS1_ENST00000449844 NPAS1 Q99742 Neuronal PAS domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 53 309 23 23 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 Census Yes 1 hippie 227 1008 107 107 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OAT OAT P04181 Ornithine aminotransferase, mitochondrial chr10 Not Cancer Driver No 1 hippie 52 17 0 0 27
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 hippie 61 79 15 15 1
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 Not Cancer Driver No 1 hippie 42 82 11 11 7
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 Not Cancer Driver No 1 intact, hippie, biogrid 86 464 54 54 12
PDIA6_ENST00000272227 PDIA6 Q15084 Protein disulfide-isomerase A6 chr2 Not Cancer Driver No 1 hippie 55 82 11 11 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLOD1 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 Not Cancer Driver No 1 hippie 86 12 0 0 5
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 Not Cancer Driver No 1 hippie 11 24 3 3 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
RCBTB2_ENST00000344532 RCBTB2 O95199 RCC1 and BTB domain-containing protein 2 chr13 Not Cancer Driver No 1 intact, hippie 86 36 3 3 0
RCN3 RCN3 Q96D15 Reticulocalbin-3 chr19 Not Cancer Driver No 1 hippie 44 243 39 39 0
RIC8A_ENST00000526104 RIC8A Q9NPQ8 Synembryn-A chr11 Not Cancer Driver No 1 hippie 63 163 23 23 0
RPL24 RPL24 P83731 60S ribosomal protein L24 chr3 Not Cancer Driver No 1 hippie 19 105 14 14 0
RPL35 RPL35 P42766 60S ribosomal protein L35 chr9 Not Cancer Driver No 1 hippie 12 65 9 9 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 Census Yes 1 hippie 57 96 17 17 2
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie 53 26 4 4 0
RPS20_ENST00000521262 RPS20 P60866 40S ribosomal protein S20 chr8 Not Cancer Driver No 1 hippie 18 53 8 8 0
RPS4X RPS4X P62701 40S ribosomal protein S4, X isoform chrX Not Cancer Driver No 1 hippie 32 35 6 6 0
RPS8 RPS8 P62241 40S ribosomal protein S8 chr1 Not Cancer Driver No 1 hippie 23 81 7 7 0
RPSA_ENST00000301821 RPSA P08865 40S ribosomal protein SA chr3 Not Cancer Driver No 1 hippie 22 95 6 6 5
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 Not Cancer Driver No 1 hippie 87 242 28 28 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 Census Yes 1 hippie 127 258 48 48 0
SSR3_ENST00000265044 SSR3 Q9UNL2 Translocon-associated protein subunit gamma chr3 Not Cancer Driver No 1 hippie 30 18 5 5 0
TMEM41B_ENST00000611268 TMEM41B Q5BJD5 Transmembrane protein 41B chr11 Not Cancer Driver No 1 hippie 19 47 3 3 0
TPM4_ENST00000300933 TPM4 P67936 Tropomyosin alpha-4 chain chr19 Census Yes 1 hippie 28 216 28 28 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 hippie 22 109 4 4 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 29 41 6 6 0