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PBX1 ,PBX1 ,P40424
  • Uniprot Accession= P40424
  • Ensembl Transcript= ENST00000420696.6
  • Uniprot Name= PBX1
  • Name= Pre-B-cell leukemia transcription factor 1
  • Chromosome= chr1
  • Driver status= Census
  • Number of Interaction partner in intact: 22
  • Number of Interaction partner in biogrid: 16
  • Number of Interaction partner in hippie: 67
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
BRMS1L BRMS1L Q5PSV4 Breast cancer metastasis-suppressor 1-like protein chr14 Not Cancer Driver No 1 hippie 35 160 17 17 0
C16orf71 DNAAF8 Q8IYS4 Dynein axonemal assembly factor 8 chr16 Not Cancer Driver No 1 intact 59 517 59 59 0
C5orf24_ENST00000435259 C5orf24 Q7Z6I8 UPF0461 protein C5orf24 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 22 182 22 22 0
CCDC120_ENST00000606812 CCDC120 Q96HB5 Coiled-coil domain-containing protein 120 chrX Not Cancer Driver No 2 intact, hippie, biogrid 71 555 67 67 0
CDCA7L CDCA7L Q96GN5 Cell division cycle-associated 7-like protein chr7 Not Cancer Driver No 1 intact, hippie 83 263 48 48 0
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
EFHC1 EFHC1 Q5JVL4 EF-hand domain-containing protein 1 chr6 Not Cancer Driver No 1 intact, hippie 79 78 15 15 17
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FAM222A FAM222A Q5U5X8 Protein FAM222A chr12 Not Cancer Driver No 2 intact, hippie, biogrid 44 263 25 25 0
FAM90A1 FAM90A1 Q86YD7 Protein FAM90A1 chr12 Not Cancer Driver No 1 intact, hippie 123 461 121 121 0
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 Census, Compendium Yes 1 intact, hippie 100 295 53 53 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 Not Cancer Driver No 1 hippie 33 411 24 24 32
FOXE1 FOXE1 O00358 Forkhead box protein E1 chr9 Not Cancer Driver No 1 hippie 38 133 5 5 4
FOXQ1 FOXQ1 Q9C009 Forkhead box protein Q1 chr6 Not Cancer Driver No 1 intact, hippie 22 245 4 4 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 47 135 10 10 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 1 hippie 65 61 8 8 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HOXA10 HOXA10 P31260 Homeobox protein Hox-A10 chr7 Not Cancer Driver No 1 hippie 35 339 25 25 0
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 Not Cancer Driver No 1 hippie 90 262 68 68 0
HOXA5 HOXA5 P20719 Homeobox protein Hox-A5 chr7 Not Cancer Driver No 1 hippie 43 209 37 37 0
HOXA9 HOXA9 P31269 Homeobox protein Hox-A9 chr7 Census Yes 1 hippie 46 187 35 35 0
HOXB1 HOXB1 P14653 Homeobox protein Hox-B1 chr17 Not Cancer Driver No 1 intact, hippie 71 276 68 68 1
HOXB5 HOXB5 P09067 Homeobox protein Hox-B5 chr17 Not Cancer Driver No 1 intact, hippie 40 203 26 26 0
HOXB7 HOXB7 P09629 Homeobox protein Hox-B7 chr17 Not Cancer Driver No 1 hippie 25 84 10 10 0
HOXB8 HOXB8 P17481 Homeobox protein Hox-B8 chr17 Not Cancer Driver No 1 hippie 35 121 15 15 0
HOXC5 HOXC5 Q00444 Homeobox protein Hox-C5 chr12 Not Cancer Driver No 1 intact, hippie 35 141 20 20 0
HOXC8 HOXC8 P31273 Homeobox protein Hox-C8 chr12 Not Cancer Driver No 2 intact, hippie 38 139 19 19 0
HOXD10 HOXD10 P28358 Homeobox protein Hox-D10 chr2 Not Cancer Driver No 1 hippie 74 230 55 55 1
HOXD4 HOXD4 P09016 Homeobox protein Hox-D4 chr2 Not Cancer Driver No 1 hippie 62 211 41 41 0
HOXD9 HOXD9 P28356 Homeobox protein Hox-D9 chr2 Not Cancer Driver No 1 hippie 47 276 30 30 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 Not Cancer Driver No 1 hippie 88 251 17 17 0
LMX1B_ENST00000373474 LMX1B O60663 LIM homeobox transcription factor 1-beta chr9 Not Cancer Driver No 3 hippie, biogrid 63 196 30 30 32
MAB21L1 MAB21L1 Q13394 Putative nucleotidyltransferase MAB21L1 chr13 Not Cancer Driver No 3 intact, hippie, biogrid 94 0 0 0 0
MAB21L2 MAB21L2 Q9Y586 Protein mab-21-like 2 chr4 Not Cancer Driver No 3 intact, hippie, biogrid 81 6 3 3 5
MAGEA1 MAGEA1 P43355 Melanoma-associated antigen 1 chrX Not Cancer Driver No 3 hippie, biogrid 68 71 15 15 0
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 Not Cancer Driver No 1 hippie 101 294 41 41 1
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MEIS1 MEIS1 O00470 Homeobox protein Meis1 chr2 Not Cancer Driver No 3 intact, hippie 89 267 62 62 0
MEIS2 MEIS2 O14770 Homeobox protein Meis2 chr15 Not Cancer Driver No 5 intact, hippie, biogrid 94 358 76 76 0
MN1 MN1 Q10571 Transcriptional activator MN1 chr22 Census Yes 1 hippie 148 1283 140 140 0
MYH10_ENST00000269243 MYH10 P35580 Myosin-10 chr17 Not Cancer Driver No 1 hippie 258 1134 136 136 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 Census Yes 1 hippie 45 246 33 33 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 Not Cancer Driver No 1 hippie 126 463 60 60 4
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 Not Cancer Driver No 1 hippie 72 337 56 56 38
PBX2 PBX2 P40425 Pre-B-cell leukemia transcription factor 2 chr6 Not Cancer Driver No 1 intact, hippie 57 297 43 43 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 Not Cancer Driver No 1 hippie 32 238 23 23 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 Not Cancer Driver No 1 hippie 17 115 12 12 0
PKNOX1 PKNOX1 P55347 Homeobox protein PKNOX1 chr21 Not Cancer Driver No 4 intact, hippie, biogrid 60 279 36 36 0
PKNOX2 PKNOX2 Q96KN3 Homeobox protein PKNOX2 chr11 Not Cancer Driver No 2 hippie, biogrid 76 322 60 60 0
POU2F1_ENST00000541643 POU2F1 P14859 POU domain, class 2, transcription factor 1 chr1 Not Cancer Driver No 1 hippie 95 433 50 50 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 Not Cancer Driver No 1 hippie 49 151 19 19 2
SHOX SHOX O15266 Short stature homeobox protein chrX Not Cancer Driver No 1 hippie, biogrid 78 169 58 58 4
SIN3B SIN3B O75182 Paired amphipathic helix protein Sin3b chr19 Not Cancer Driver No 1 hippie 130 316 32 32 0
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 Census, Compendium Yes 1 hippie 349 1072 195 195 5
SMARCD3 SMARCD3 Q6STE5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 chr7 Not Cancer Driver No 1 hippie 64 213 18 18 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 intact, hippie 63 332 44 44 0
SRPRB SRPRB Q9Y5M8 Signal recognition particle receptor subunit beta chr3 Not Cancer Driver No 1 hippie, biogrid 30 23 3 3 0
TLX1 TLX1 P31314 T-cell leukemia homeobox protein 1 chr10 Census Yes 1 intact, hippie 28 223 17 17 0
TMOD3 TMOD3 Q9NYL9 Tropomodulin-3 chr15 Not Cancer Driver No 1 hippie, biogrid 40 190 24 24 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 1 hippie 51 63 9 9 0
TSHZ2 TSHZ2 Q9NRE2 Teashirt homolog 2 chr20 Not Cancer Driver No 1 hippie, biogrid 323 784 241 241 0
UCHL3 UCHL3 P15374 Ubiquitin carboxyl-terminal hydrolase isozyme L3 chr13 Not Cancer Driver No 1 hippie, biogrid 26 61 3 3 0
USP9X_ENST00000378308 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX Census, Compendium Yes 1 hippie 339 405 51 51 1
VWA5A VWA5A O00534 von Willebrand factor A domain-containing protein 5A chr11 Not Cancer Driver No 2 intact, hippie, biogrid 145 137 37 37 0