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PATJ ,PATJ ,Q8NI35
  • Number of Interaction partner in intact: 23
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 116
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADGRB1_ENST00000323289 ADGRB1 O14514 Adhesion G protein-coupled receptor B1 chr8 Compendium Yes 1 hippie 213 485 47 47 0
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 Census Yes 1 hippie 248 1247 180 180 0
AMOT AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 1 hippie 161 909 128 128 0
AMOTL1 AMOTL1 Q8IY63 Angiomotin-like protein 1 chr11 Not Cancer Driver No 1 intact, hippie 136 851 121 121 0
AMOTL2_ENST00000422605 AMOTL2 Q9Y2J4 Angiomotin-like protein 2 chr3 Not Cancer Driver No 1 hippie 94 741 93 93 0
ANAPC15_ENST00000538393 ANAPC15 P60006 Anaphase-promoting complex subunit 15 chr11 Not Cancer Driver No 1 hippie 15 117 14 14 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
ARHGAP17 ARHGAP17 Q68EM7 Rho GTPase-activating protein 17 chr16 Not Cancer Driver No 1 hippie 123 547 72 72 0
ARHGAP45_ENST00000313093 ARHGAP45 Q92619 Rho GTPase-activating protein 45 chr19 Not Cancer Driver No 1 intact, hippie 110 679 68 68 0
AZGP1 AZGP1 P25311 Zinc-alpha-2-glycoprotein chr7 Not Cancer Driver No 1 intact, hippie 59 41 10 10 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 intact, hippie 37 104 14 14 0
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
C2CD4B C2CD4B A6NLJ0 C2 calcium-dependent domain-containing protein 4B chr15 Not Cancer Driver No 1 hippie 5 191 0 0 0
CACNG2 CACNG2 Q9Y698 Voltage-dependent calcium channel gamma-2 subunit chr22 Not Cancer Driver No 1 hippie 57 90 16 16 1
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CEP57L1 CEP57L1 Q8IYX8 Centrosomal protein CEP57L1 chr6 Not Cancer Driver No 1 hippie 42 289 24 24 0
CINP CINP Q9BW66 Cyclin-dependent kinase 2-interacting protein chr14 Not Cancer Driver No 1 hippie 22 41 5 5 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLDN1 CLDN1 O95832 Claudin-1 chr3 Not Cancer Driver No 1 hippie 31 16 3 3 0
CNKSR2 CNKSR2 Q8WXI2 Connector enhancer of kinase suppressor of ras 2 chrX Not Cancer Driver No 1 hippie 217 518 116 116 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 Compendium Yes 1 hippie 42 30 0 0 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CRB1 CRB1 P82279 Protein crumbs homolog 1 chr1 Not Cancer Driver No 1 hippie 464 28 5 5 74
CRB3_ENST00000598494 CRB3 Q9BUF7 Protein crumbs homolog 3 chr19 Not Cancer Driver No 1 hippie 12 53 7 7 0
CRIPT CRIPT Q9P021 Cysteine-rich PDZ-binding protein chr2 Not Cancer Driver No 1 hippie 14 29 3 3 1
DDX18 DDX18 Q9NVP1 ATP-dependent RNA helicase DDX18 chr2 Not Cancer Driver No 1 hippie 111 239 36 36 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 Not Cancer Driver No 1 hippie 77 294 39 39 0
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 Not Cancer Driver No 1 intact, hippie 74 121 17 17 3
EEF1AKMT3 EEF1AKMT3 Q96AZ1 EEF1A lysine methyltransferase 3 chr12 Not Cancer Driver No 1 hippie 23 33 1 1 0
EPB41L4A_ENST00000621003 EPB41L4A Q9HCS5 Band 4.1-like protein 4A chr5 Not Cancer Driver No 1 hippie 119 378 65 65 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
F2RL2 F2RL2 O00254 Proteinase-activated receptor 3 chr5 Not Cancer Driver No 1 hippie 54 0 0 0 0
FAM124A_ENST00000322475 FAM124A Q86V42 Protein FAM124A chr13 Not Cancer Driver No 1 hippie 69 357 39 39 0
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie 30 0 0 0 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie 43 122 15 15 0
FRMD6 FRMD6 Q96NE9 FERM domain-containing protein 6 chr14 Not Cancer Driver No 1 intact, hippie 116 195 36 36 0
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 Not Cancer Driver No 1 hippie 74 38 5 5 171
GIPC2 GIPC2 Q8TF65 PDZ domain-containing protein GIPC2 chr1 Not Cancer Driver No 1 hippie 48 51 2 2 0
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 Not Cancer Driver No 1 hippie 34 0 0 0 46
GLS2 GLS2 Q9UI32 Glutaminase liver isoform, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 108 9 9 0
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 Not Cancer Driver No 1 intact, hippie 45 24 2 2 16
GNB4_ENST00000468623 GNB4 Q9HAV0 Guanine nucleotide-binding protein subunit beta-4 chr3 Not Cancer Driver No 1 intact, hippie 49 27 3 3 2
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 Census, Compendium Yes 1 hippie 528 506 207 207 31
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 Not Cancer Driver No 1 hippie 413 426 147 147 11
GRIN2C GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 Not Cancer Driver No 1 hippie 111 276 6 6 0
GRIN2D GRIN2D O15399 Glutamate receptor ionotropic, NMDA 2D chr19 Not Cancer Driver No 1 hippie 125 467 15 15 1
H2AFX H2AX P16104 Histone H2AX chr11 Not Cancer Driver No 1 intact 20 68 10 10 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 Not Cancer Driver No 1 intact 23 71 16 16 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 Not Cancer Driver No 1 hippie 91 570 50 50 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HOMER1 HOMER1 Q86YM7 Homer protein homolog 1 chr5 Not Cancer Driver No 1 intact, hippie 46 243 32 32 0
HOMER2 HOMER2 Q9NSB8 Homer protein homolog 2 chr15 Not Cancer Driver No 1 intact, hippie 53 233 32 32 1
HOMER3_ENST00000542541 HOMER3 Q9NSC5 Homer protein homolog 3 chr19 Not Cancer Driver No 1 intact, hippie 31 251 15 15 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
HSF2 HSF2 Q03933 Heat shock factor protein 2 chr6 Not Cancer Driver No 1 hippie 64 292 37 37 0
KCNA4 KCNA4 P22459 Potassium voltage-gated channel subfamily A member 4 chr11 Not Cancer Driver No 1 hippie 213 233 82 82 0
KCNJ10 KCNJ10 P78508 ATP-sensitive inward rectifier potassium channel 10 chr1 Not Cancer Driver No 1 hippie 78 28 10 10 8
KCNJ15_ENST00000398934 KCNJ15 Q99712 ATP-sensitive inward rectifier potassium channel 15 chr21 Not Cancer Driver No 1 hippie 85 12 2 2 0
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 Not Cancer Driver No 1 hippie 103 49 11 11 12
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 1 hippie 253 633 106 106 1
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
KRT6C KRT6C P48668 Keratin, type II cytoskeletal 6C chr12 Not Cancer Driver No 1 hippie 100 141 38 38 1
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 Census, Compendium Yes 1 hippie 161 788 100 100 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 hippie 178 687 116 116 0
LIN7A LIN7A O14910 Protein lin-7 homolog A chr12 Not Cancer Driver No 2 intact, hippie 76 127 29 29 0
LIN7B LIN7B Q9HAP6 Protein lin-7 homolog B chr19 Not Cancer Driver No 1 hippie 26 107 16 16 0
LIN7C LIN7C Q9NUP9 Protein lin-7 homolog C chr11 Not Cancer Driver No 1 hippie 22 102 11 11 0
LURAP1 LURAP1 Q96LR2 Leucine rich adaptor protein 1 chr1 Not Cancer Driver No 1 hippie 30 169 18 18 0
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 1 intact, hippie 260 1212 220 220 0
MAPK12 MAPK12 P53778 Mitogen-activated protein kinase 12 chr22 Not Cancer Driver No 1 hippie 31 63 5 5 0
MPP5 PALS1 Q8N3R9 Protein PALS1 chr14 Not Cancer Driver No 1 intact 70 337 33 33 0
MYCBP MYCBP Q99417 c-Myc-binding protein chr1 Not Cancer Driver No 1 hippie 8 54 4 4 0
NDUFB7 NDUFB7 P17568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 chr19 Not Cancer Driver No 1 hippie 17 65 6 6 0
NECAB2 NECAB2 Q7Z6G3 N-terminal EF-hand calcium-binding protein 2 chr16 Not Cancer Driver No 1 hippie 46 122 9 9 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 2 intact, hippie 69 252 26 26 16
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 Not Cancer Driver No 1 hippie 91 300 19 19 0
NRXN2_ENST00000377551 NRXN2 Q9P2S2 Neurexin-2 chr11 Not Cancer Driver No 1 hippie 278 547 80 80 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie 200 1144 170 170 2
PARD6A PARD6A Q9NPB6 Partitioning defective 6 homolog alpha chr16 Not Cancer Driver No 1 hippie 25 177 13 13 0
PATJ PATJ Q8NI35 InaD-like protein chr1 Not Cancer Driver No 1 hippie 261 918 142 142 0
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 Not Cancer Driver No 1 hippie 72 337 56 56 38
PCDHAC2 PCDHAC2 Q9Y5I4 Protocadherin alpha-C2 chr5 Not Cancer Driver No 1 intact, hippie 215 416 94 94 0
PHYH PHYH O14832 Phytanoyl-CoA dioxygenase, peroxisomal chr10 Not Cancer Driver No 1 hippie 54 40 4 4 14
PKP4 PKP4 Q99569 Plakophilin-4 chr2 Not Cancer Driver No 1 hippie 172 756 119 119 0
PLEKHG5_ENST00000400913 PLEKHG5 O94827 Pleckstrin homology domain-containing family G member 5 chr1 Not Cancer Driver No 1 hippie 93 537 54 54 3
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRDM16 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 Census Yes 1 hippie 254 830 152 152 1
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 1 hippie 94 154 22 22 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
RAB32 RAB32 Q13637 Ras-related protein Rab-32 chr6 Not Cancer Driver No 1 hippie 18 40 2 2 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie 52 19 2 2 0
RNASEH2A RNASEH2A O75792 Ribonuclease H2 subunit A chr19 Not Cancer Driver No 1 hippie 42 31 3 3 7
RNF146 RNF146 Q9NTX7 E3 ubiquitin-protein ligase RNF146 chr6 Not Cancer Driver No 1 hippie 37 206 24 24 0
RNF166 RNF166 Q96A37 E3 ubiquitin-protein ligase RNF166 chr16 Not Cancer Driver No 2 intact, hippie 18 24 2 2 0
RPL26L1 RPL26L1 Q9UNX3 60S ribosomal protein L26-like 1 chr5 Not Cancer Driver No 1 intact, hippie 21 107 11 11 0
SAV1 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 Not Cancer Driver No 1 hippie 42 243 17 17 0
SCN4A SCN4A P35499 Sodium channel protein type 4 subunit alpha chr17 Not Cancer Driver No 1 hippie 324 372 80 80 60
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 Not Cancer Driver No 1 hippie 491 550 144 144 190
SLC25A32 SLC25A32 Q9H2D1 Mitochondrial folate transporter/carrier chr8 Not Cancer Driver No 1 hippie 45 4 0 0 1
SLC33A1_ENST00000643144 SLC33A1 O00400 Acetyl-coenzyme A transporter 1 chr3 Not Cancer Driver No 1 hippie 64 54 8 8 2
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 1 hippie 21 107 13 13 5
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TANC1 TANC1 Q9C0D5 Protein TANC1 chr2 Not Cancer Driver No 1 hippie 237 906 101 101 0
TJP3_ENST00000541714 TJP3 O95049 Tight junction protein ZO-3 chr19 Not Cancer Driver No 1 hippie 132 684 101 101 0
TMA16 TMA16 Q96EY4 Translation machinery-associated protein 16 chr4 Not Cancer Driver No 1 intact, hippie 25 112 10 10 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TP53RK TP53RK Q96S44 EKC/KEOPS complex subunit TP53RK chr20 Not Cancer Driver No 1 hippie 20 51 2 2 3
TUBB1 TUBB1 Q9H4B7 Tubulin beta-1 chain chr20 Not Cancer Driver No 1 intact, hippie 71 38 4 4 1
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 59 86 6 6 0
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie 39 335 34 34 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WWC1_ENST00000265293 WWC1 Q8IX03 Protein KIBRA chr5 Not Cancer Driver No 1 hippie 147 550 81 81 0
WWP1 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 Not Cancer Driver No 1 hippie 139 431 75 75 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 2 intact, hippie 51 489 49 49 0