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PARP1 ,PARP1 ,P09874
  • Number of Interaction partner in intact: 110
  • Number of Interaction partner in biogrid: 351
  • Number of Interaction partner in hippie: 725
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
ABRAXAS1 ABRAXAS1 Q6UWZ7 BRCA1-A complex subunit Abraxas 1 chr4 Not Cancer Driver No 1 hippie 38 112 15 15 1
ACOT9_ENST00000336430 ACOT9 Q9Y305 Acyl-coenzyme A thioesterase 9, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 45 45 3 3 0
AFF4 AFF4 Q9UHB7 AF4/FMR2 family member 4 chr5 Census Yes 1 hippie, biogrid 138 993 121 121 3
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AGRN AGRN O00468 Agrin chr1 Not Cancer Driver No 1 hippie 188 490 40 40 5
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX Not Cancer Driver No 1 hippie 98 0 0 0 0
AIMP2 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 Not Cancer Driver No 1 hippie 46 61 8 8 0
AIRE AIRE O43918 Autoimmune regulator chr21 Not Cancer Driver No 1 hippie 71 338 48 48 19
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 Census Yes 1 biogrid 77 84 9 9 2
ALDH16A1 ALDH16A1 Q8IZ83 Aldehyde dehydrogenase family 16 member A1 chr19 Not Cancer Driver No 1 hippie, biogrid 90 175 26 26 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie, biogrid 144 767 104 104 2
ANP32E ANP32E Q9BTT0 Acidic leucine-rich nuclear phosphoprotein 32 family member E chr1 Not Cancer Driver No 2 hippie, biogrid 40 135 18 18 0
AP3M1 AP3M1 Q9Y2T2 AP-3 complex subunit mu-1 chr10 Not Cancer Driver No 1 hippie, biogrid 45 19 1 1 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 biogrid 34 103 14 14 0
APLF APLF Q8IW19 Aprataxin and PNK-like factor chr2 Not Cancer Driver No 6 intact, hippie, biogrid 64 407 57 57 0
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 Not Cancer Driver No 1 hippie 36 101 6 6 9
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 hippie 84 181 32 32 0
ARHGAP5 ARHGAP5 Q13017 Rho GTPase-activating protein 5 chr14 Census, Compendium Yes 1 hippie, biogrid 249 418 50 50 0
ARID3A ARID3A Q99856 AT-rich interactive domain-containing protein 3A chr19 Not Cancer Driver No 1 hippie, biogrid 55 432 37 37 0
ARID3B ARID3B Q8IVW6 AT-rich interactive domain-containing protein 3B chr15 Not Cancer Driver No 1 hippie, biogrid 72 394 57 57 0
ARID4B ARID4B Q4LE39 AT-rich interactive domain-containing protein 4B chr1 Not Cancer Driver No 1 hippie, biogrid 143 1005 118 118 0
ARL1 ARL1 P40616 ADP-ribosylation factor-like protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 17 4 0 0 0
ASH2L ASH2L Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 chr8 Not Cancer Driver No 1 hippie 95 293 39 39 0
ATAD2 ATAD2 Q6PL18 ATPase family AAA domain-containing protein 2 chr8 Not Cancer Driver No 1 hippie, biogrid 227 647 113 113 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 Not Cancer Driver No 1 hippie, biogrid 200 1075 112 112 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 hippie 469 225 39 39 41
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 Not Cancer Driver No 1 hippie, biogrid 136 78 14 14 41
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 hippie 66 23 5 5 2
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie, biogrid 51 63 8 8 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 biogrid 29 195 9 9 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 Not Cancer Driver No 1 hippie 10 11 2 2 1
BANP_ENST00000286122 BANP Q8N9N5 Protein BANP chr16 Not Cancer Driver No 1 hippie 74 311 43 43 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 Census Yes 1 hippie 96 384 49 49 0
BAZ1A_ENST00000382422 BAZ1A Q9NRL2 Bromodomain adjacent to zinc finger domain protein 1A chr14 Census Yes 1 hippie, biogrid 156 752 65 65 0
BBX BBX Q8WY36 HMG box transcription factor BBX chr3 Not Cancer Driver No 1 hippie, biogrid 147 842 125 125 0
BCL11A BCL11A Q9H165 B-cell lymphoma/leukemia 11A chr2 Census, Compendium Yes 1 hippie, biogrid 210 677 171 171 3
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 Census, Compendium Yes 1 hippie 24 72 5 5 0
BCORL1_ENST00000218147 BCORL1 Q5H9F3-1 Isoform 1 of BCL-6 corepressor-like protein 1 chrX Census, Compendium Yes 1 hippie, biogrid 264 1365 212 212 0
BEND3_ENST00000369042 BEND3 Q5T5X7 BEN domain-containing protein 3 chr6 Not Cancer Driver No 1 hippie, biogrid 104 311 44 44 0
BICRA BICRA Q9NZM4 BRD4-interacting chromatin-remodeling complex-associated protein chr19 Not Cancer Driver No 1 hippie 75 1340 63 63 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 65 456 42 42 5
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BLID BLID Q8IZY5 BH3-like motif-containing cell death inducer chr11 Not Cancer Driver No 1 intact, hippie 25 0 0 0 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 Not Cancer Driver No 1 intact, hippie 94 75 21 21 0
BLM BLM P54132 Bloom syndrome protein chr15 Census Yes 2 hippie, biogrid 153 667 70 70 8
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 2 intact, hippie 50 150 30 30 0
BMS1 BMS1 Q14692 Ribosome biogenesis protein BMS1 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 179 708 88 88 1
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 Census, Compendium Yes 1 hippie 791 310 43 43 39
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 2 hippie, biogrid 224 1458 174 174 35
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 Census, Compendium Yes 1 intact 457 1542 225 225 46
BRD2_ENST00000374831 BRD2 P25440 Bromodomain-containing protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 108 632 85 85 0
BRD3 BRD3 Q15059 Bromodomain-containing protein 3 chr9 Census Yes 1 hippie, biogrid 87 566 68 68 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 Not Cancer Driver No 1 hippie 90 399 45 45 4
BRIX1 BRIX1 Q8TDN6 Ribosome biogenesis protein BRX1 homolog chr5 Not Cancer Driver No 1 hippie, biogrid 34 149 10 10 0
BTAF1 BTAF1 O14981 TATA-binding protein-associated factor 172 chr10 Not Cancer Driver No 1 hippie, biogrid 215 360 52 52 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 Census Yes 1 hippie 96 480 35 35 7
BUB3 BUB3 O43684 Mitotic checkpoint protein BUB3 chr10 Not Cancer Driver No 1 hippie 46 60 6 6 0
C9orf43_ENST00000374165 C9orf43 Q8TAL5 Uncharacterized protein C9orf43 chr9 Not Cancer Driver No 1 intact, hippie 65 309 45 45 0
C9orf78 C9orf78 Q9NZ63 Telomere length and silencing protein 1 homolog chr9 Not Cancer Driver No 1 hippie, biogrid 32 285 32 32 0
CAMK2B CAMK2B Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta chr7 Not Cancer Driver No 1 biogrid 86 273 28 28 6
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CARM1 CARM1 Q86X55 Histone-arginine methyltransferase CARM1 chr19 Not Cancer Driver No 1 hippie 62 102 10 10 0
CASP1 CASP1 P29466 Caspase-1 chr11 Not Cancer Driver No 1 hippie 79 87 18 18 0
CASP3 CASP3 P42574 Caspase-3 chr4 Census Yes 1 hippie 32 62 5 5 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 Not Cancer Driver No 1 hippie 38 73 10 10 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 hippie 142 106 12 12 1
CASZ1 CASZ1 Q86V15 Zinc finger protein castor homolog 1 chr1 Compendium Yes 1 hippie, biogrid 237 1077 152 152 0
CBX1_ENST00000225603 CBX1 P83916 Chromobox protein homolog 1 chr17 Not Cancer Driver No 1 hippie, biogrid 31 154 25 25 0
CBX2 CBX2 Q14781 Chromobox protein homolog 2 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 56 487 53 53 2
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 Not Cancer Driver No 1 hippie, biogrid 23 119 18 18 0
CBX4 CBX4 O00257 E3 SUMO-protein ligase CBX4 chr17 Not Cancer Driver No 1 hippie 72 477 63 63 0
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 Not Cancer Driver No 1 hippie, biogrid 21 116 12 12 0
CBX8 CBX8 Q9HC52 Chromobox protein homolog 8 chr17 Not Cancer Driver No 1 hippie, biogrid 59 309 51 51 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 29 54 9 9 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 Not Cancer Driver No 1 intact, hippie 90 56 18 18 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 Not Cancer Driver No 1 hippie 26 95 11 11 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 1 hippie, biogrid 110 210 39 39 2
CDCA2 CDCA2 Q69YH5 Cell division cycle-associated protein 2 chr8 Not Cancer Driver No 1 hippie, biogrid 124 828 100 100 0
CDCA8_ENST00000327331 CDCA8 Q53HL2 Borealin chr1 Not Cancer Driver No 1 hippie, biogrid 23 170 13 13 0
CDK11A CDK11A Q9UQ88 Cyclin-dependent kinase 11A chr1 Not Cancer Driver No 1 hippie, biogrid 66 485 44 44 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 Not Cancer Driver No 1 hippie 217 1136 128 128 0
CDK8 CDK8 P49336 Cyclin-dependent kinase 8 chr13 Not Cancer Driver No 1 hippie 76 152 18 18 7
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 50 34 2 2 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 hippie 48 121 30 30 0
CDYL_ENST00000328908 CDYL Q9Y232 Chromodomain Y-like protein chr6 Not Cancer Driver No 1 hippie, biogrid 99 346 61 61 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 Census, Compendium Yes 1 intact, hippie 12 342 12 12 1
CEBPZ CEBPZ Q03701 CCAAT/enhancer-binding protein zeta chr2 Not Cancer Driver No 1 hippie, biogrid 95 488 44 44 0
CENPA CENPA P49450 Histone H3-like centromeric protein A chr2 Not Cancer Driver No 1 hippie 15 50 4 4 0
CENPB CENPB P07199 Major centromere autoantigen B chr20 Not Cancer Driver No 1 hippie 64 374 39 39 0
CENPC CENPC Q03188 Centromere protein C chr4 Not Cancer Driver No 1 hippie, biogrid 96 790 84 84 0
CETN1 CETN1 Q12798 Centrin-1 chr18 Not Cancer Driver No 1 hippie 65 105 43 43 0
CETN2 CETN2 P41208 Centrin-2 chrX Not Cancer Driver No 1 hippie 33 97 11 11 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 287 145 18 18 151
CHD1 CHD1 O14646 Chromodomain-helicase-DNA-binding protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 172 975 109 109 4
CHD1L CHD1L Q86WJ1 Chromodomain-helicase-DNA-binding protein 1-like chr1 Not Cancer Driver No 3 intact, hippie, biogrid 98 225 30 30 0
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 235 1015 122 122 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 hippie 419 974 177 177 6
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 Not Cancer Driver No 1 hippie, biogrid 393 1469 213 213 0
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 464 1872 299 299 50
CHERP CHERP Q8IWX8 Calcium homeostasis endoplasmic reticulum protein chr19 Not Cancer Driver No 1 hippie, biogrid 109 707 79 79 0
CHFR CHFR Q96EP1 E3 ubiquitin-protein ligase CHFR chr12 Not Cancer Driver No 2 intact, hippie 85 341 54 54 0
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CIZ1_ENST00000634901 CIZ1 Q9ULV3 Cip1-interacting zinc finger protein chr9 Not Cancer Driver No 1 hippie, biogrid 93 708 83 83 0
CLSPN CLSPN Q9HAW4 Claspin chr1 Not Cancer Driver No 1 hippie, biogrid 151 1283 147 147 0
CMTR1 CMTR1 Q8N1G2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 chr6 Not Cancer Driver No 2 hippie, biogrid 81 176 20 20 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 hippie, biogrid 61 84 13 13 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 Not Cancer Driver No 1 hippie 62 133 18 18 0
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 Census, Compendium Yes 1 hippie 151 481 83 83 1
CTDSPL2 CTDSPL2 Q05D32 CTD small phosphatase-like protein 2 chr15 Not Cancer Driver No 1 hippie 47 256 27 27 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 Not Cancer Driver No 1 hippie, biogrid 164 385 48 48 0
CTSB CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 1 hippie 41 7 2 2 0
CTSG CTSG P08311 Cathepsin G chr14 Not Cancer Driver No 1 hippie 65 80 29 29 0
CTSL CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 47 34 4 4 0
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 hippie 151 65 9 9 0
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
CUX1_ENST00000622516 CUX1 Q13948 Protein CASP chr7 Census, Compendium Yes 1 hippie, biogrid 114 347 64 64 0
CWC27 CWC27 Q6UX04 Spliceosome-associated protein CWC27 homolog chr5 Not Cancer Driver No 1 hippie, biogrid 60 345 43 43 0
CWF19L2 CWF19L2 Q2TBE0 CWF19-like protein 2 chr11 Not Cancer Driver No 1 hippie, biogrid 119 615 83 83 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
CYP4F12_ENST00000324632 CYP4F12 Q9HCS2 Cytochrome P450 4F12 chr19 Not Cancer Driver No 1 biogrid 138 18 4 4 0
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 Not Cancer Driver No 1 hippie, biogrid 157 641 134 134 0
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 Census, Compendium Yes 1 intact, hippie 106 549 81 81 0
DBP DBP Q10586 D site-binding protein chr19 Not Cancer Driver No 1 intact 24 280 18 18 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 Census, Compendium Yes 1 hippie 45 70 5 5 2
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX10 DDX10 Q13206 Probable ATP-dependent RNA helicase DDX10 chr11 Census Yes 1 hippie, biogrid 93 400 46 46 0
DDX18 DDX18 Q9NVP1 ATP-dependent RNA helicase DDX18 chr2 Not Cancer Driver No 1 hippie, biogrid 111 239 36 36 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 Not Cancer Driver No 1 hippie, biogrid 72 342 30 30 0
DDX27 DDX27 Q96GQ7 Probable ATP-dependent RNA helicase DDX27 chr20 Not Cancer Driver No 1 hippie, biogrid 101 383 50 50 0
DDX31_ENST00000372153 DDX31 Q9H8H2 Probable ATP-dependent RNA helicase DDX31 chr9 Not Cancer Driver No 1 hippie, biogrid 99 342 38 38 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie 44 37 2 2 0
DDX41 DDX41 Q9UJV9 Probable ATP-dependent RNA helicase DDX41 chr5 Not Cancer Driver No 1 hippie, biogrid 82 180 26 26 1
DDX49 DDX49 Q9Y6V7 Probable ATP-dependent RNA helicase DDX49 chr19 Not Cancer Driver No 1 hippie, biogrid 55 78 6 6 0
DDX50 DDX50 Q9BQ39 ATP-dependent RNA helicase DDX50 chr10 Not Cancer Driver No 1 hippie, biogrid 86 274 30 30 0
DDX51 DDX51 Q8N8A6 ATP-dependent RNA helicase DDX51 chr12 Not Cancer Driver No 1 hippie, biogrid 51 244 8 8 0
DDX54_ENST00000306014 DDX54 Q8TDD1 ATP-dependent RNA helicase DDX54 chr12 Not Cancer Driver No 1 hippie, biogrid 113 458 52 52 0
DDX55 DDX55 Q8NHQ9 ATP-dependent RNA helicase DDX55 chr12 Not Cancer Driver No 1 hippie, biogrid 51 130 6 6 0
DDX56 DDX56 Q9NY93 Probable ATP-dependent RNA helicase DDX56 chr7 Not Cancer Driver No 1 hippie, biogrid 50 107 13 13 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie 28 11 1 1 0
DGCR8 DGCR8 Q8WYQ5 Microprocessor complex subunit DGCR8 chr22 Census, Compendium Yes 1 hippie 102 466 57 57 0
DHCR7 DHCR7 Q9UBM7 7-dehydrocholesterol reductase chr11 Not Cancer Driver No 1 hippie, biogrid 85 7 1 1 53
DHX16 DHX16 O60231 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 chr6 Not Cancer Driver No 1 hippie, biogrid 128 391 59 59 1
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 Not Cancer Driver No 1 hippie, biogrid 53 125 12 12 0
DIDO1 DIDO1 Q9BTC0 Death-inducer obliterator 1 chr20 Not Cancer Driver No 1 hippie 453 1917 400 400 0
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX Not Cancer Driver No 1 hippie, biogrid 62 145 29 29 24
DNAJC8 DNAJC8 O75937 DnaJ homolog subfamily C member 8 chr1 Not Cancer Driver No 1 hippie, biogrid 29 188 23 23 0
DNAJC9 DNAJC9 Q8WXX5 DnaJ homolog subfamily C member 9 chr10 Not Cancer Driver No 2 hippie, biogrid 28 126 15 15 0
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 Not Cancer Driver No 2 hippie, biogrid 203 702 78 78 4
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 Census, Compendium Yes 1 hippie, biogrid 194 371 59 59 16
DNMT3B DNMT3B Q9UBC3 DNA (cytosine-5)-methyltransferase 3B chr20 Not Cancer Driver No 1 intact, hippie 153 328 71 71 16
DNTTIP2 DNTTIP2 Q5QJE6 Deoxynucleotidyltransferase terminal-interacting protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 82 698 77 77 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 Not Cancer Driver No 1 intact, hippie 49 210 25 25 0
DTX2 DTX2 Q86UW9 Probable E3 ubiquitin-protein ligase DTX2 chr7 Not Cancer Driver No 1 hippie 84 292 42 42 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 Not Cancer Driver No 1 hippie 86 260 24 24 0
DTX3_ENST00000337737 DTX3 Q8N9I9 Probable E3 ubiquitin-protein ligase DTX3 chr12 Not Cancer Driver No 1 hippie 58 182 31 31 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 Not Cancer Driver No 1 hippie 49 272 23 23 0
E2F3 E2F3 O00716 Transcription factor E2F3 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 46 253 20 20 0
E4F1 E4F1 Q66K89 Transcription factor E4F1 chr16 Not Cancer Driver No 1 hippie 84 462 46 46 0
EBNA1BP2_ENST00000236051 EBNA1BP2 Q99848 Probable rRNA-processing protein EBP2 chr1 Not Cancer Driver No 1 hippie, biogrid 38 254 34 34 0
ECD_ENST00000372979 ECD O95905 Protein ecdysoneless homolog chr10 Not Cancer Driver No 1 hippie, biogrid 68 254 26 26 0
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 Not Cancer Driver No 1 hippie 104 311 39 39 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EHMT1 EHMT1 Q9H9B1 Histone-lysine N-methyltransferase EHMT1 chr9 Not Cancer Driver No 1 hippie, biogrid 182 701 97 97 1
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ELF2 ELF2 Q15723 ETS-related transcription factor Elf-2 chr4 Not Cancer Driver No 1 hippie, biogrid 59 423 43 43 0
ELOA_ENST00000613537 ELOA Q14241 Elongin-A chr1 Not Cancer Driver No 1 hippie 77 652 62 62 0
EMC4 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 hippie 15 17 2 2 0
EMX2 EMX2 Q04743 Homeobox protein EMX2 chr10 Not Cancer Driver No 1 hippie, biogrid 34 147 21 21 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 Not Cancer Driver No 1 hippie 397 2064 234 234 0
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 Census Yes 1 hippie, biogrid 120 225 27 27 15
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 Not Cancer Driver No 1 hippie 211 829 117 117 9
ERG_ENST00000288319 ERG P11308 Transcriptional regulator ERG chr21 Census, Compendium Yes 1 intact, hippie 95 296 54 54 0
ESF1 ESF1 Q9H501 ESF1 homolog chr20 Not Cancer Driver No 1 hippie, biogrid 129 684 109 109 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 Not Cancer Driver No 1 hippie 68 78 9 9 0
ETV1 ETV1 P50549 ETS translocation variant 1 chr7 Census Yes 1 intact, hippie 100 282 66 66 0
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie 94 646 93 93 0
EXOSC1 EXOSC1 Q9Y3B2 Exosome complex component CSL4 chr10 Not Cancer Driver No 1 hippie 14 14 2 2 1
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 83 241 34 34 0
FAM169A FAM169A Q9Y6X4 Soluble lamin-associated protein of 75 kDa chr5 Not Cancer Driver No 1 hippie, biogrid 92 415 38 38 0
FAM50A FAM50A Q14320 Protein FAM50A chrX Not Cancer Driver No 1 hippie, biogrid 40 203 21 21 4
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FANCI FANCI Q9NVI1 Fanconi anemia group I protein chr15 Not Cancer Driver No 1 hippie, biogrid 161 129 20 20 2
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 Not Cancer Driver No 1 hippie 33 19 0 0 4
FBXL6 FBXL6 Q8N531 F-box/LRR-repeat protein 6 chr8 Not Cancer Driver No 1 hippie 48 114 5 5 0
FLYWCH1 FLYWCH1 Q4VC44 FLYWCH-type zinc finger-containing protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 66 432 38 38 0
FMNL1 FMNL1 O95466 Formin-like protein 1 chr17 Not Cancer Driver No 1 hippie 115 524 32 32 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 Not Cancer Driver No 1 hippie, biogrid 33 411 24 24 32
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 Census, Compendium Yes 1 hippie 81 584 75 75 0
FTSJ3 FTSJ3 Q8IY81 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 chr17 Not Cancer Driver No 1 hippie, biogrid 103 533 66 66 0
FUS FUS P35637 RNA-binding protein FUS chr16 Census Yes 1 intact, hippie 51 524 51 51 20
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GATAD2B_ENST00000634544 GATAD2B Q8WXI9 Transcriptional repressor p66-beta chr1 Not Cancer Driver No 1 hippie, biogrid 76 510 67 67 0
GLYR1 GLYR1 Q49A26 Putative oxidoreductase GLYR1 chr16 Not Cancer Driver No 1 hippie, biogrid 87 201 27 27 0
GNL2 GNL2 Q13823 Nucleolar GTP-binding protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 87 446 51 51 0
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 Not Cancer Driver No 1 hippie, biogrid 56 257 21 21 0
GPATCH4_ENST00000368232 GPATCH4 A0A0A0MRK1 G patch domain-containing protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 42 359 39 39 0
GPKOW GPKOW Q92917 G-patch domain and KOW motifs-containing protein chrX Not Cancer Driver No 1 hippie, biogrid 80 396 71 71 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 Not Cancer Driver No 1 hippie 55 180 8 8 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 56 146 13 13 0
GTF2E1 GTF2E1 P29083 General transcription factor IIE subunit 1 chr3 Not Cancer Driver No 1 hippie, biogrid 71 264 48 48 0
GTF2F1 GTF2F1 P35269 General transcription factor IIF subunit 1 chr19 Not Cancer Driver No 2 hippie, biogrid 63 426 48 48 0
GTF3C1 GTF3C1 Q12789 General transcription factor 3C polypeptide 1 chr16 Not Cancer Driver No 1 hippie, biogrid 323 735 114 114 0
GTF3C2 GTF3C2 Q8WUA4 General transcription factor 3C polypeptide 2 chr2 Not Cancer Driver No 1 hippie, biogrid 111 394 45 45 0
GTF3C3 GTF3C3 Q9Y5Q9 General transcription factor 3C polypeptide 3 chr2 Not Cancer Driver No 1 hippie, biogrid 109 195 22 22 0
GTF3C5_ENST00000372097 GTF3C5 Q9Y5Q8 General transcription factor 3C polypeptide 5 chr9 Not Cancer Driver No 1 hippie, biogrid 75 157 21 21 0
GTPBP4 GTPBP4 Q9BZE4 GTP-binding protein 4 chr10 Not Cancer Driver No 1 hippie, biogrid 79 232 34 34 0
GZMB GZMB P10144 Granzyme B chr14 Not Cancer Driver No 1 hippie 49 103 23 23 0
GZMM GZMM P51124 Granzyme M chr19 Not Cancer Driver No 1 hippie 25 12 1 1 0
H2AFX H2AX P16104 Histone H2AX chr11 Not Cancer Driver No 5 intact 20 68 10 10 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 Not Cancer Driver No 1 intact 46 125 19 19 0
HACD3 HACD3 Q9P035 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 chr15 Not Cancer Driver No 1 hippie 28 10 0 0 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 2 hippie, biogrid 47 135 10 10 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 2 hippie, biogrid 46 145 14 14 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 1 hippie 65 61 8 8 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 118 718 73 73 0
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 Not Cancer Driver No 1 hippie 286 631 178 178 0
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 Not Cancer Driver No 1 hippie 59 622 57 57 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 2 intact, hippie, biogrid 35 203 29 29 0
HEATR1 HEATR1 Q9H583 HEAT repeat-containing protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 291 43 5 5 0
HECTD1 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 Not Cancer Driver No 1 intact, hippie 274 991 108 108 0
HELLS_ENST00000348459 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 Not Cancer Driver No 1 hippie, biogrid 78 227 25 25 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 Not Cancer Driver No 1 hippie 37 226 32 32 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 118 435 51 51 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 Not Cancer Driver No 1 hippie 154 686 96 96 0
HIST1H2BH H2BC9 Q93079 Histone H2B type 1-H chr6 Not Cancer Driver No 1 intact 42 79 20 20 0
HIVEP1 HIVEP1 P15822 Zinc finger protein 40 chr6 Not Cancer Driver No 1 hippie 344 2238 292 292 0
HMGA1 HMGA1 P17096 High mobility group protein HMG-I/HMG-Y chr6 Census Yes 1 hippie 6 107 6 6 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 Census Yes 1 hippie, biogrid 12 109 12 12 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 Not Cancer Driver No 3 intact, hippie, biogrid 25 203 20 20 0
HMGB3 HMGB3 O15347 High mobility group protein B3 chrX Not Cancer Driver No 1 hippie, biogrid 37 182 32 32 0
HMGN1 HMGN1 P05114 Non-histone chromosomal protein HMG-14 chr21 Not Cancer Driver No 1 hippie 12 100 12 12 0
HMGN2 HMGN2 P05204 Non-histone chromosomal protein HMG-17 chr1 Not Cancer Driver No 1 hippie 10 90 10 10 0
HMGN4 HMGN4 O00479 High mobility group nucleosome-binding domain-containing protein 4 chr6 Not Cancer Driver No 1 hippie 9 90 9 9 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie 39 206 19 19 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HOXA2 HOXA2 O43364 Homeobox protein Hox-A2 chr7 Not Cancer Driver No 1 hippie 58 281 48 48 1
HOXB7 HOXB7 P09629 Homeobox protein Hox-B7 chr17 Not Cancer Driver No 1 hippie 25 84 10 10 0
HPF1 HPF1 Q9NWY4 Histone PARylation factor 1 chr4 Not Cancer Driver No 1 hippie 32 23 0 0 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 24 200 13 13 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie 93 286 38 38 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie 155 419 90 90 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 Census, Compendium Yes 1 intact, hippie 106 211 31 31 1
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 intact, hippie 108 76 13 13 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 intact, hippie 6 301 6 6 22
IL24_ENST00000294984 IL24 Q13007 Interleukin-24 chr1 Not Cancer Driver No 1 intact, hippie 35 0 0 0 0
ILF3_ENST00000590261 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 Not Cancer Driver No 1 hippie, biogrid 103 674 82 82 0
ILKAP ILKAP Q9H0C8 Integrin-linked kinase-associated serine/threonine phosphatase 2C chr2 Not Cancer Driver No 1 hippie, biogrid 60 154 28 28 0
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie 97 400 50 50 0
INCENP INCENP Q9NQS7 Inner centromere protein chr11 Not Cancer Driver No 1 hippie, biogrid 107 856 103 103 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 Compendium Yes 1 hippie 173 682 76 76 0
INTS1 INTS1 Q8N201 Integrator complex subunit 1 chr7 Not Cancer Driver No 1 hippie, biogrid 234 368 43 43 1
IPO4 IPO4 Q8TEX9 Importin-4 chr14 Not Cancer Driver No 1 hippie, biogrid 106 87 5 5 0
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 Not Cancer Driver No 1 hippie, biogrid 128 52 3 3 0
IRF2 IRF2 P14316 Interferon regulatory factor 2 chr4 Not Cancer Driver No 1 intact, hippie 85 288 73 73 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 70 18 3 3 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
IVNS1ABP IVNS1ABP Q9Y6Y0 Influenza virus NS1A-binding protein chr1 Not Cancer Driver No 1 hippie 85 90 12 12 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 Not Cancer Driver No 1 hippie 107 266 27 27 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 Census Yes 1 hippie, biogrid 97 327 47 47 0
KCTD12 KCTD12 Q96CX2 BTB/POZ domain-containing protein KCTD12 chr13 Not Cancer Driver No 1 hippie 15 147 4 4 0
KDELR1 KDELR1 P24390 ER lumen protein-retaining receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 32 0 0 0 0
KDM2A KDM2A Q9Y2K7 Lysine-specific demethylase 2A chr11 Not Cancer Driver No 1 hippie, biogrid 131 387 48 48 0
KDM2B KDM2B Q8NHM5 Lysine-specific demethylase 2B chr12 Not Cancer Driver No 1 hippie, biogrid 187 617 90 90 0
KIAA0556 KATNIP O60303 Katanin-interacting protein chr16 Not Cancer Driver No 1 intact 240 982 137 137 0
KIF18B KIF18B Q86Y91 Kinesin-like protein KIF18B chr17 Not Cancer Driver No 1 hippie, biogrid 100 590 69 69 0
KIF22 KIF22 Q14807 Kinesin-like protein KIF22 chr16 Not Cancer Driver No 1 hippie, biogrid 79 322 35 35 4
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie, biogrid 102 559 62 62 0
KIF4A KIF4A O95239 Chromosome-associated kinesin KIF4A chrX Not Cancer Driver No 1 hippie, biogrid 188 674 116 116 0
KIFC1 KIFC1 Q9BW19 Kinesin-like protein KIFC1 chr6 Compendium Yes 1 hippie, biogrid 99 450 67 67 0
KIN KIN O60870 DNA/RNA-binding protein KIN17 chr10 Not Cancer Driver No 1 hippie 52 137 13 13 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 Compendium Yes 1 hippie 77 366 40 40 0
KLF8 KLF8 O95600 Krueppel-like factor 8 chrX Not Cancer Driver No 1 hippie 71 270 53 53 0
KNOP1 KNOP1 Q1ED39 Lysine-rich nucleolar protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 44 402 39 39 0
KPNA2_ENST00000330459 KPNA2 P52292 Importin subunit alpha-1 chr17 Not Cancer Driver No 1 intact, hippie 74 129 18 18 0
KPNA3 KPNA3 O00505 Importin subunit alpha-4 chr13 Not Cancer Driver No 1 hippie, biogrid 65 108 11 11 0
KPNA5 KPNA5 O15131 Importin subunit alpha-6 chr6 Not Cancer Driver No 1 hippie, biogrid 65 133 13 13 0
KRI1 KRI1 Q8N9T8 Protein KRI1 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 91 607 84 84 0
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 149 534 114 114 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LAS1L LAS1L Q9Y4W2 Ribosomal biogenesis protein LAS1L chrX Not Cancer Driver No 1 hippie, biogrid 100 279 49 49 0
LEMD3 LEMD3 Q9Y2U8 Inner nuclear membrane protein Man1 chr12 Not Cancer Driver No 1 hippie, biogrid 78 509 33 33 0
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 hippie, biogrid 74 611 69 69 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 1 hippie 15 133 6 6 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 54 65 16 16 0
LIG1 LIG1 P18858 DNA ligase 1 chr19 Not Cancer Driver No 1 biogrid 137 397 62 62 0
LIG3 LIG3 P49916 DNA ligase 3 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 125 280 36 36 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 2 intact, hippie 68 544 49 49 131
LMTK2 LMTK2 Q8IWU2 Serine/threonine-protein kinase LMTK2 chr7 Not Cancer Driver No 1 intact 211 1018 141 141 0
LRIF1 LRIF1 Q5T3J3 Ligand-dependent nuclear receptor-interacting factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 116 520 74 74 0
LRRC31 LRRC31 Q6UY01 Leucine-rich repeat-containing protein 31 chr3 Not Cancer Driver No 1 intact, hippie 109 80 10 10 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 Not Cancer Driver No 1 intact 103 301 30 30 0
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 Not Cancer Driver No 1 hippie, biogrid 50 249 31 31 0
LZTR1_ENST00000646124 LZTR1 Q8N653 Leucine-zipper-like transcriptional regulator 1 chr22 Census, Compendium Yes 1 intact, hippie 160 106 18 18 26
MACROD1 MACROD1 Q9BQ69 ADP-ribose glycohydrolase MACROD1 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 24 45 1 1 0
MAFF_ENST00000426621 MAFF Q9ULX9 Transcription factor MafF chr22 Not Cancer Driver No 1 hippie 9 118 7 7 0
MAFG MAFG O15525 Transcription factor MafG chr17 Not Cancer Driver No 1 hippie 5 132 5 5 0
MAFK MAFK O60675 Transcription factor MafK chr7 Not Cancer Driver No 1 hippie 13 135 12 12 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 hippie 10 17 1 1 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 Not Cancer Driver No 1 intact, hippie 51 50 15 15 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 intact, hippie 62 2 0 0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 38 49 5 5 0
MAST3 MAST3 O60307 Microtubule-associated serine/threonine-protein kinase 3 chr19 Not Cancer Driver No 1 intact, hippie 169 783 100 100 0
MCM4 MCM4 P33991 DNA replication licensing factor MCM4 chr8 Not Cancer Driver No 1 hippie, biogrid 121 215 35 35 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 Not Cancer Driver No 1 hippie 162 1104 117 117 0
MED14 MED14 O60244 Mediator of RNA polymerase II transcription subunit 14 chrX Not Cancer Driver No 1 hippie 182 318 45 45 0
MED17 MED17 Q9NVC6 Mediator of RNA polymerase II transcription subunit 17 chr11 Not Cancer Driver No 1 hippie 75 182 17 17 1
MED23 MED23 Q9ULK4 Mediator of RNA polymerase II transcription subunit 23 chr6 Not Cancer Driver No 1 hippie 158 28 2 2 1
MED24_ENST00000394128 MED24 O75448 Mediator of RNA polymerase II transcription subunit 24 chr17 Not Cancer Driver No 1 hippie 101 76 0 0 0
MED6_ENST00000256379 MED6 O75586 Mediator of RNA polymerase II transcription subunit 6 chr14 Not Cancer Driver No 1 hippie 21 79 4 4 0
MED7 MED7 O43513 Mediator of RNA polymerase II transcription subunit 7 chr5 Not Cancer Driver No 1 hippie 32 132 19 19 0
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie, biogrid 76 446 42 42 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 Not Cancer Driver No 1 hippie 60 224 26 26 0
METTL22 METTL22 Q9BUU2 Methyltransferase-like protein 22 chr16 Not Cancer Driver No 1 hippie 55 160 19 19 0
MEX3C MEX3C Q5U5Q3 RNA-binding E3 ubiquitin-protein ligase MEX3C chr18 Not Cancer Driver No 1 intact, hippie 54 475 32 32 0
MFAP1 MFAP1 P55081 Microfibrillar-associated protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 58 377 53 53 0
MGA MGA Q8IWI9 MAX gene-associated protein chr15 Compendium Yes 1 hippie, biogrid 341 2317 259 259 0
MLLT1 MLLT1 Q03111 Protein ENL chr19 Census, Compendium Yes 1 hippie, biogrid 68 413 43 43 0
MORC1 MORC1 Q86VD1 MORC family CW-type zinc finger protein 1 chr3 Not Cancer Driver No 1 hippie 300 252 77 77 0
MORC2 MORC2 Q9Y6X9 ATPase MORC2 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 125 523 69 69 16
MORC3 MORC3 Q14149 MORC family CW-type zinc finger protein 3 chr21 Not Cancer Driver No 1 hippie, biogrid 113 394 45 45 0
MOSPD2 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX Not Cancer Driver No 1 intact, hippie 58 143 16 16 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MPHOSPH10 MPHOSPH10 O00566 U3 small nucleolar ribonucleoprotein protein MPP10 chr2 Not Cancer Driver No 1 hippie, biogrid 105 518 82 82 0
MPND_ENST00000262966 MPND Q8N594 MPN domain-containing protein chr19 Not Cancer Driver No 1 hippie, biogrid 45 168 8 8 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 Not Cancer Driver No 1 intact, hippie 84 292 35 35 1
MSANTD2 MSANTD2 Q6P1R3 Myb/SANT-like DNA-binding domain-containing protein 2 chr11 Not Cancer Driver No 1 hippie, biogrid 47 211 9 9 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 Census Yes 1 hippie, biogrid 92 37 4 4 70
MSH3 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 Not Cancer Driver No 1 hippie, biogrid 100 211 20 20 0
MST1R MST1R Q04912 Macrophage-stimulating protein receptor chr3 Not Cancer Driver No 1 intact 178 182 27 27 1
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 Not Cancer Driver No 1 hippie, biogrid 78 283 32 32 0
MTA3 MTA3 Q9BTC8 Metastasis-associated protein MTA3 chr2 Not Cancer Driver No 1 intact, hippie 48 169 18 18 0
MTF1 MTF1 Q14872 Metal regulatory transcription factor 1 chr1 Not Cancer Driver No 1 hippie 115 553 76 76 0
MTF2 MTF2 Q9Y483 Metal-response element-binding transcription factor 2 chr1 Not Cancer Driver No 1 hippie, biogrid 70 225 28 28 0
MYBL2 MYBL2 P10244 Myb-related protein B chr20 Not Cancer Driver No 1 hippie 111 506 85 85 0
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 Census Yes 1 hippie 82 528 69 69 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYSM1 MYSM1 Q5VVJ2 Deubiquitinase MYSM1 chr1 Not Cancer Driver No 1 hippie, biogrid 78 345 26 26 1
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NADSYN1 NADSYN1 Q6IA69 Glutamine-dependent NAD(+) synthetase chr11 Not Cancer Driver No 1 hippie 82 27 8 8 3
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 Not Cancer Driver No 2 hippie, biogrid 109 142 18 18 0
NBN NBN O60934 Nibrin chr8 Census Yes 1 hippie 90 417 54 54 1
NCAPD2 NCAPD2 Q15021 Condensin complex subunit 1 chr12 Not Cancer Driver No 1 hippie 124 345 35 35 0
NCAPG NCAPG Q9BPX3 Condensin complex subunit 3 chr4 Not Cancer Driver No 1 hippie 85 154 13 13 0
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 intact 88 89 8 8 0
NCL NCL P19338 Nucleolin chr2 Not Cancer Driver No 2 hippie, biogrid 85 569 68 68 0
NCOA6 NCOA6 Q14686 Nuclear receptor coactivator 6 chr20 Not Cancer Driver No 1 hippie 242 1941 219 219 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 123 117 42 42 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NEIL3 NEIL3 Q8TAT5 Endonuclease 8-like 3 chr4 Not Cancer Driver No 1 hippie 80 131 18 18 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
NEPRO NEPRO Q6NW34 Nucleolus and neural progenitor protein chr3 Not Cancer Driver No 1 hippie 62 147 28 28 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NFATC1 NFATC1 O95644 Nuclear factor of activated T-cells, cytoplasmic 1 chr18 Not Cancer Driver No 1 hippie 173 713 130 130 0
NFATC2 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 Census, Compendium Yes 1 hippie, biogrid 194 722 162 162 0
NFATC2IP NFATC2IP Q8NCF5 NFATC2-interacting protein chr16 Not Cancer Driver No 1 hippie, biogrid 41 330 29 29 0
NFIA_ENST00000403491 NFIA Q12857 Nuclear factor 1 A-type chr1 Not Cancer Driver No 1 hippie, biogrid 78 347 55 55 0
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 Census Yes 1 hippie, biogrid 63 254 36 36 3
NFIC NFIC P08651 Nuclear factor 1 C-type chr19 Not Cancer Driver No 1 hippie 61 327 44 44 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 2 intact, hippie 104 344 38 38 0
NFKB2 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 Census, Compendium Yes 1 intact, hippie 86 510 46 46 0
NFX1 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 121 491 46 46 0
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 Compendium Yes 1 hippie, biogrid 353 1528 184 184 37
NIPSNAP2 NIPSNAP2 O75323 Protein NipSnap homolog 2 chr7 Not Cancer Driver No 1 intact, hippie 30 6 1 1 0
NKAPD1_ENST00000420986 NKAPD1 Q6ZUT1 Uncharacterized protein NKAPD1 chr11 Not Cancer Driver No 1 hippie 35 261 31 31 0
NKRF_ENST00000304449 NKRF O15226 NF-kappa-B-repressing factor chrX Not Cancer Driver No 1 hippie, biogrid 100 366 49 49 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 Census, Compendium Yes 1 hippie 41 334 39 39 7
NMNAT1 NMNAT1 Q9HAN9 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 chr1 Not Cancer Driver No 1 intact, hippie 39 49 7 7 28
NOC2L NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 77 281 31 31 0
NOC3L NOC3L Q8WTT2 Nucleolar complex protein 3 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 75 281 29 29 0
NOL10 NOL10 Q9BSC4 Nucleolar protein 10 chr2 Not Cancer Driver No 1 hippie, biogrid 52 182 22 22 0
NOL11 NOL11 Q9H8H0 Nucleolar protein 11 chr17 Not Cancer Driver No 1 hippie, biogrid 76 54 9 9 0
NOL8_ENST00000442668 NOL8 Q76FK4 Nucleolar protein 8 chr9 Not Cancer Driver No 1 hippie, biogrid 127 978 109 109 0
NOLC1_ENST00000605788 NOLC1 Q14978 Nucleolar and coiled-body phosphoprotein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 74 662 69 69 0
NOP14 NOP14 P78316 Nucleolar protein 14 chr4 Not Cancer Driver No 1 hippie, biogrid 87 521 46 46 0
NOP2_ENST00000322166 NOP2 P46087 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase chr12 Not Cancer Driver No 1 hippie, biogrid 116 510 72 72 0
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 Not Cancer Driver No 1 hippie 59 391 41 41 0
NOP56 NOP56 O00567 Nucleolar protein 56 chr20 Not Cancer Driver No 1 hippie, biogrid 83 191 34 34 0
NOP58 NOP58 Q9Y2X3 Nucleolar protein 58 chr2 Not Cancer Driver No 1 hippie, biogrid 47 156 14 14 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie 363 686 87 87 3
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 2 hippie, biogrid 29 249 22 22 0
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 Not Cancer Driver No 1 hippie 21 10 1 1 0
NR2C1 NR2C1 P13056 Nuclear receptor subfamily 2 group C member 1 chr12 Not Cancer Driver No 1 hippie, biogrid 65 156 13 13 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NRF1_ENST00000393230 NRF1 Q16656 Nuclear respiratory factor 1 chr7 Not Cancer Driver No 1 hippie 68 265 31 31 0
NSD1 NSD1 Q96L73 Histone-lysine N-methyltransferase, H3 lysine-36 specific chr5 Census, Compendium Yes 1 hippie, biogrid 343 1864 206 206 14
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 Census, Compendium Yes 1 hippie 191 552 76 76 0
NSD3 NSD3 Q9BZ95 Histone-lysine N-methyltransferase NSD3 chr8 Census Yes 1 hippie 164 679 98 98 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUDCD3 NUDCD3 Q8IVD9 NudC domain-containing protein 3 chr7 Not Cancer Driver No 1 intact, hippie 30 199 16 16 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 Not Cancer Driver No 1 hippie 29 8 1 1 0
NUP188 NUP188 Q5SRE5 Nucleoporin NUP188 chr9 Not Cancer Driver No 1 hippie, biogrid 190 152 20 20 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 Not Cancer Driver No 1 hippie, biogrid 90 267 31 31 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OARD1 OARD1 Q9Y530 ADP-ribose glycohydrolase OARD1 chr6 Not Cancer Driver No 1 intact, hippie 14 13 0 0 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
ORC3_ENST00000392844 ORC3 Q9UBD5 Origin recognition complex subunit 3 chr6 Not Cancer Driver No 1 hippie, biogrid 70 63 5 5 0
OVOL2 OVOL2 Q9BRP0 Transcription factor Ovo-like 2 chr20 Not Cancer Driver No 1 hippie 29 139 8 8 0
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 77 378 56 56 0
PAGE4_ENST00000376141 PAGE4 O60829 P antigen family member 4 chrX Not Cancer Driver No 1 hippie 20 102 20 20 0
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie 58 340 33 33 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PARG_ENST00000616448 PARG Q86W56 Poly(ADP-ribose) glycohydrolase chr10 Not Cancer Driver No 2 intact, hippie, biogrid 60 519 1 1 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 Not Cancer Driver No 1 hippie, biogrid 71 197 22 22 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 3 intact, hippie 119 320 34 34 0
PARP2 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 Not Cancer Driver No 2 intact, hippie 74 172 23 23 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 Not Cancer Driver No 1 hippie 70 269 38 38 0
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 Not Cancer Driver No 1 hippie 110 45 3 3 0
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 Census Yes 1 hippie 84 291 55 55 4
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 Not Cancer Driver No 1 hippie, biogrid 46 13 5 5 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 30 22 3 3 1
PDCD11 PDCD11 Q14690 Protein RRP5 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 212 487 64 64 0
PDLIM7 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 Not Cancer Driver No 1 hippie 48 244 20 20 0
PDS5A PDS5A Q29RF7 Sister chromatid cohesion protein PDS5 homolog A chr4 Not Cancer Driver No 1 hippie, biogrid 150 295 34 34 0
PDS5B PDS5B Q9NTI5 Sister chromatid cohesion protein PDS5 homolog B chr13 Not Cancer Driver No 1 hippie, biogrid 174 455 61 61 0
PELI1 PELI1 Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 chr2 Not Cancer Driver No 1 hippie 47 167 17 17 0
PES1 PES1 O00541 Pescadillo homolog chr22 Not Cancer Driver No 1 hippie, biogrid 78 248 33 33 0
PGR PGR P06401 Progesterone receptor chr11 Not Cancer Driver No 2 intact, hippie 161 480 55 55 0
PHC1_ENST00000544916 PHC1 P78364 Polyhomeotic-like protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 82 851 69 69 1
PHC3_ENST00000494943 PHC3 Q8NDX5 Polyhomeotic-like protein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 102 795 85 85 0
PHF10 PHF10 Q8WUB8 PHD finger protein 10 chr6 Not Cancer Driver No 1 hippie, biogrid 39 298 26 26 0
PHF2 PHF2 O75151 Lysine-specific demethylase PHF2 chr9 Not Cancer Driver No 1 hippie, biogrid 131 725 80 80 0
PHF3 PHF3 Q92576 PHD finger protein 3 chr6 Not Cancer Driver No 1 hippie, biogrid 260 1718 217 217 0
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX Not Cancer Driver No 1 hippie, biogrid 154 603 93 93 1
PHIP PHIP Q8WWQ0 PH-interacting protein chr6 Not Cancer Driver No 1 hippie, biogrid 239 835 110 110 0
PIAS1_ENST00000249636 PIAS1 O75925 E3 SUMO-protein ligase PIAS1 chr15 Not Cancer Driver No 1 hippie, biogrid 80 241 43 43 0
PIAS2 PIAS2 O75928 E3 SUMO-protein ligase PIAS2 chr18 Not Cancer Driver No 2 hippie, biogrid 78 209 28 28 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 Not Cancer Driver No 1 hippie 58 142 23 23 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PINX1 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 Not Cancer Driver No 1 hippie, biogrid 66 328 66 66 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 Not Cancer Driver No 1 hippie 53 177 23 23 4
POGZ POGZ Q7Z3K3 Pogo transposable element with ZNF domain chr1 Not Cancer Driver No 1 hippie, biogrid 157 746 78 78 0
POLA1_ENST00000379059 POLA1 P09884 DNA polymerase alpha catalytic subunit chrX Not Cancer Driver No 1 hippie 185 347 45 45 3
POLA2 POLA2 Q14181 DNA polymerase alpha subunit B chr11 Not Cancer Driver No 1 hippie 63 102 16 16 0
POLB POLB P06746 DNA polymerase beta chr8 Not Cancer Driver No 3 intact, hippie, biogrid 43 87 11 11 0
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 Not Cancer Driver No 1 hippie 64 46 4 4 3
POLR1E POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 Not Cancer Driver No 1 hippie, biogrid 39 85 6 6 0
POU2F1_ENST00000541643 POU2F1 P14859 POU domain, class 2, transcription factor 1 chr1 Not Cancer Driver No 1 hippie 95 433 50 50 0
PPAN PPAN Q9NQ55 Suppressor of SWI4 1 homolog chr19 Not Cancer Driver No 1 hippie 65 257 42 42 0
PPAN-P2RY11_ENST00000428358 PPAN-P2RY11 Q9NQ55-3 Isoform 3 of Suppressor of SWI4 1 homolog chr19 Not Cancer Driver No 1 biogrid 81 275 52 52 0
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 Not Cancer Driver No 1 intact, hippie 125 845 99 99 0
PPM1G PPM1G O15355 Protein phosphatase 1G chr2 Not Cancer Driver No 2 hippie, biogrid 51 359 39 39 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 hippie, biogrid 47 25 5 5 5
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 Not Cancer Driver No 1 hippie 83 628 72 72 0
PPP2R2A_ENST00000380737 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 Not Cancer Driver No 1 intact, hippie 60 68 10 10 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 Not Cancer Driver No 1 hippie 37 0 0 0 23
PRDM16 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 Census Yes 1 hippie 254 830 152 152 1
PRDM2 PRDM2 Q13029 PR domain zinc finger protein 2 chr1 Census, Compendium Yes 1 hippie, biogrid 242 1340 199 199 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 intact, hippie 72 124 17 17 0
PRKAB1 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 Not Cancer Driver No 1 intact, hippie 39 124 13 13 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 3 intact, hippie 538 421 61 61 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie 50 18 1 1 0
PRPF31 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie, biogrid 58 213 17 17 2
PRPF6 PRPF6 O94906 Pre-mRNA-processing factor 6 chr20 Not Cancer Driver No 1 hippie, biogrid 140 379 62 62 1
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PSIP1_ENST00000380738 PSIP1 O75475 PC4 and SFRS1-interacting protein chr9 Census, Compendium Yes 1 hippie, biogrid 75 481 71 71 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 Not Cancer Driver No 1 hippie 134 425 55 55 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 174 291 99 99 0
RACGAP1_ENST00000454520 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 74 255 27 27 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 2 hippie, biogrid 59 328 43 43 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 1 hippie, biogrid 115 421 74 74 3
RAD23A RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 Not Cancer Driver No 1 hippie 50 283 41 41 0
RAD51AP1 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 46 335 43 43 0
RAI1 RAI1 Q7Z5J4 Retinoic acid-induced protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 208 1690 188 188 0
RANBP6 RANBP6 O60518 Ran-binding protein 6 chr9 Not Cancer Driver No 1 hippie, biogrid 152 46 4 4 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 Census, Compendium Yes 2 intact, hippie 70 167 14 14 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 Census, Compendium Yes 1 hippie, biogrid 140 282 32 32 22
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 hippie 202 578 75 75 0
RBM14 RBM14 Q96PK6 RNA-binding protein 14 chr11 Not Cancer Driver No 1 hippie 99 350 59 59 0
RBM19 RBM19 Q9Y4C8 Probable RNA-binding protein 19 chr12 Not Cancer Driver No 1 hippie, biogrid 146 514 76 76 0
RBM28 RBM28 Q9NW13 RNA-binding protein 28 chr7 Not Cancer Driver No 1 hippie, biogrid 97 512 66 66 1
RBM34 RBM34 P42696 RNA-binding protein 34 chr1 Not Cancer Driver No 1 hippie, biogrid 50 267 34 34 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RBM45_ENST00000616198 RBM45 Q8IUH3 RNA-binding protein 45 chr2 Not Cancer Driver No 1 hippie 56 105 20 20 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 1 hippie 10 18 1 1 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 158 796 115 115 0
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie 33 23 0 0 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 Not Cancer Driver No 1 hippie, biogrid 132 495 71 71 0
RECQL_ENST00000421138 RECQL P46063 ATP-dependent DNA helicase Q1 chr12 Not Cancer Driver No 1 intact, hippie 67 91 5 5 0
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 2 intact, hippie 75 400 48 48 0
REST REST Q13127 RE1-silencing transcription factor chr4 Not Cancer Driver No 1 hippie 142 868 113 113 4
REXO4 REXO4 Q9GZR2 RNA exonuclease 4 chr9 Not Cancer Driver No 1 hippie, biogrid 34 298 26 26 0
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 Not Cancer Driver No 1 hippie, biogrid 45 39 6 6 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 Not Cancer Driver No 1 hippie, biogrid 38 20 1 1 0
RFX5_ENST00000452671 RFX5 P48382 DNA-binding protein RFX5 chr1 Not Cancer Driver No 1 hippie, biogrid 80 467 60 60 1
RGS8_ENST00000367556 RGS8 P57771 Regulator of G-protein signaling 8 chr1 Not Cancer Driver No 1 intact, hippie 41 20 5 5 0
RIOK2 RIOK2 Q9BVS4 Serine/threonine-protein kinase RIO2 chr5 Not Cancer Driver No 1 intact, hippie 68 253 33 33 0
RLF RLF Q13129 Zinc finger protein Rlf chr1 Not Cancer Driver No 1 hippie, biogrid 194 672 55 55 0
RNF144A RNF144A P50876 E3 ubiquitin-protein ligase RNF144A chr2 Not Cancer Driver No 1 hippie 63 0 0 0 0
RNF146 RNF146 Q9NTX7 E3 ubiquitin-protein ligase RNF146 chr6 Not Cancer Driver No 3 hippie, biogrid 37 206 24 24 0
RNF166 RNF166 Q96A37 E3 ubiquitin-protein ligase RNF166 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 18 24 2 2 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 Not Cancer Driver No 1 hippie 77 471 66 66 0
RNF169 RNF169 Q8NCN4 E3 ubiquitin-protein ligase RNF169 chr11 Not Cancer Driver No 1 hippie, biogrid 52 637 46 46 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie, biogrid 40 203 22 22 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RNH1_ENST00000397604 RNH1 P13489 Ribonuclease inhibitor chr11 Not Cancer Driver No 1 intact, hippie 40 0 0 0 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 51 98 6 6 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 4 hippie, biogrid 28 114 16 16 0
RPA3 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 13 4 1 1 0
RPA4 RPA4 Q13156 Replication protein A 30 kDa subunit chrX Not Cancer Driver No 2 intact, hippie, biogrid 66 58 15 15 0
RPL10_ENST00000369817 RPL10 P27635 60S ribosomal protein L10 chrX Census, Compendium Yes 1 intact, hippie 46 9 3 3 4
RPL11 RPL11 P62913 60S ribosomal protein L11 chr1 Not Cancer Driver No 1 hippie 27 12 1 1 1
RPL14_ENST00000396203 RPL14 P50914 60S ribosomal protein L14 chr3 Not Cancer Driver No 1 hippie 21 129 13 13 0
RPL19 RPL19 P84098 60S ribosomal protein L19 chr17 Not Cancer Driver No 1 hippie 30 121 21 21 0
RPL27A RPL27A P46776 60S ribosomal protein L27a chr11 Not Cancer Driver No 1 hippie 7 56 2 2 0
RPL3 RPL3 P39023 60S ribosomal protein L3 chr22 Not Cancer Driver No 1 hippie, biogrid 34 79 3 3 0
RPL35 RPL35 P42766 60S ribosomal protein L35 chr9 Not Cancer Driver No 1 hippie 12 65 9 9 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 Census Yes 2 hippie, biogrid 57 96 17 17 2
RPS11 RPS11 P62280 40S ribosomal protein S11 chr19 Not Cancer Driver No 1 hippie, biogrid 18 6 0 0 0
RPS23 RPS23 P62266 40S ribosomal protein S23 chr5 Not Cancer Driver No 1 hippie, biogrid 8 35 1 1 2
RPS3A RPS3A P61247 40S ribosomal protein S3a chr4 Compendium Yes 1 hippie 21 85 5 5 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 Not Cancer Driver No 1 hippie 94 178 32 32 0
RPS8 RPS8 P62241 40S ribosomal protein S8 chr1 Not Cancer Driver No 1 hippie 23 81 7 7 0
RREB1_ENST00000349384 RREB1 Q92766 Ras-responsive element-binding protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 213 1152 144 144 0
RRP12 RRP12 Q5JTH9 RRP12-like protein chr10 Not Cancer Driver No 1 hippie, biogrid 155 336 56 56 0
RRP15 RRP15 Q9Y3B9 RRP15-like protein chr1 Not Cancer Driver No 1 hippie, biogrid 50 278 48 48 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 3 intact, hippie, biogrid 74 513 48 48 0
RRS1 RRS1 Q15050 Ribosome biogenesis regulatory protein homolog chr8 Not Cancer Driver No 1 hippie, biogrid 23 315 18 18 0
RSBN1 RSBN1 Q5VWQ0 Lysine-specific demethylase 9 chr1 Not Cancer Driver No 1 hippie, biogrid 111 411 52 52 0
RSBN1L RSBN1L Q6PCB5 Lysine-specific demethylase RSBN1L chr7 Not Cancer Driver No 1 hippie, biogrid 106 506 73 73 0
RSF1 RSF1 Q96T23 Remodeling and spacing factor 1 chr11 Not Cancer Driver No 1 hippie, biogrid 153 1170 130 130 0
RTF1 RTF1 Q92541 RNA polymerase-associated protein RTF1 homolog chr15 Not Cancer Driver No 1 hippie, biogrid 83 568 67 67 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 Compendium Yes 1 hippie 90 184 26 26 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 Not Cancer Driver No 1 hippie 55 85 4 4 0
SATB2 SATB2 Q9UPW6 DNA-binding protein SATB2 chr2 Not Cancer Driver No 1 hippie, biogrid 164 412 100 100 0
SCAF1 SCAF1 Q9H7N4 Splicing factor, arginine/serine-rich 19 chr19 Not Cancer Driver No 1 hippie, biogrid 135 1307 134 134 0
SCAF11 SCAF11 Q99590 Protein SCAF11 chr12 Not Cancer Driver No 1 hippie, biogrid 167 1149 134 134 0
SDAD1 SDAD1 Q9NVU7 Protein SDA1 homolog chr4 Not Cancer Driver No 1 hippie, biogrid 65 288 29 29 0
SENP1 SENP1 Q9P0U3 Sentrin-specific protease 1 chr12 Not Cancer Driver No 1 hippie 64 355 44 44 0
SENP3_ENST00000429205 SENP3 Q9H4L4 Sentrin-specific protease 3 chr17 Not Cancer Driver No 1 hippie 53 288 30 30 0
SENP6 SENP6 Q9GZR1 Sentrin-specific protease 6 chr6 Not Cancer Driver No 1 hippie, biogrid 120 612 59 59 0
SERPINH1_ENST00000358171 SERPINH1 P50454 Serpin H1 chr11 Not Cancer Driver No 1 hippie, biogrid 51 52 6 6 1
SETD1A SETD1A O15047 Histone-lysine N-methyltransferase SETD1A chr16 Not Cancer Driver No 1 hippie 223 1327 188 188 5
SGO2 SGO2 Q562F6 Shugoshin 2 chr2 Not Cancer Driver No 1 hippie 164 1025 134 134 0
SH3GL3_ENST00000427482 SH3GL3 Q99963 Endophilin-A3 chr15 Not Cancer Driver No 1 hippie 88 83 23 23 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 58 5 5 1
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 Not Cancer Driver No 1 hippie 70 435 31 31 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SLC25A1 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 22 34 2 2 17
SLC25A13_ENST00000265631 SLC25A13 Q9UJS0 Calcium-binding mitochondrial carrier protein Aralar2 chr7 Not Cancer Driver No 1 hippie, biogrid 111 23 2 2 1
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 177 34 8 8 0
SLU7 SLU7 O95391 Pre-mRNA-splicing factor SLU7 chr5 Not Cancer Driver No 1 hippie, biogrid 75 436 63 63 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 Not Cancer Driver No 1 intact, hippie 271 1573 232 232 0
SMARCA1_ENST00000371122 SMARCA1 P28370 Probable global transcription activator SNF2L1 chrX Compendium Yes 2 hippie, biogrid 143 309 41 41 0
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 Not Cancer Driver No 1 hippie, biogrid 273 1009 160 160 42
SMARCAD1_ENST00000354268 SMARCAD1 Q9H4L7 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 chr4 Not Cancer Driver No 2 hippie, biogrid 129 388 50 50 0
SMARCC1 SMARCC1 Q92922 SWI/SNF complex subunit SMARCC1 chr3 Not Cancer Driver No 1 hippie, biogrid 125 720 81 81 0
SMARCC2_ENST00000267064 SMARCC2 Q8TAQ2 SWI/SNF complex subunit SMARCC2 chr12 Not Cancer Driver No 1 hippie, biogrid 175 876 133 133 4
SMARCE1 SMARCE1 Q969G3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 chr17 Census Yes 1 hippie, biogrid 47 332 36 36 2
SMC1A SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX Census, Compendium Yes 1 hippie, biogrid 200 717 114 114 21
SMCHD1 SMCHD1 A6NHR9 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 chr18 Not Cancer Driver No 1 hippie, biogrid 240 342 45 45 45
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 Not Cancer Driver No 1 hippie 87 242 28 28 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 Census Yes 1 hippie, biogrid 127 258 48 48 0
SNRNP27 SNRNP27 Q8WVK2 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein chr2 Not Cancer Driver No 1 intact, hippie, biogrid 20 155 20 20 0
SNURF SNURF Q9Y675 SNRPN upstream reading frame protein chr15 Not Cancer Driver No 1 intact 19 67 19 19 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 Not Cancer Driver No 1 intact, hippie 46 187 34 34 0
SPP1 SPP1 P10451 Osteopontin chr4 Not Cancer Driver No 1 hippie 56 296 54 54 0
SPTA1_ENST00000368147 SPTA1 P02549 Spectrin alpha chain, erythrocytic 1 chr1 Not Cancer Driver No 1 intact, hippie 1046 707 294 294 21
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie, biogrid 54 267 32 32 30
SRBD1 SRBD1 Q8N5C6 S1 RNA-binding domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 110 279 29 29 0
SRCAP SRCAP Q6ZRS2 Helicase SRCAP chr16 Not Cancer Driver No 1 hippie, biogrid 438 2534 340 340 0
SREK1_ENST00000380918 SREK1 Q8WXA9 Splicing regulatory glutamine/lysine-rich protein 1 chr5 Not Cancer Driver No 1 hippie 60 438 53 53 0
SRF SRF P11831 Serum response factor chr6 Not Cancer Driver No 1 intact, hippie 44 443 42 42 0
SRFBP1 SRFBP1 Q8NEF9 Serum response factor-binding protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 48 350 41 41 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 27 0 0 0 6
SSRP1 SSRP1 Q08945 FACT complex subunit SSRP1 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 92 308 35 35 0
STAG1 STAG1 Q8WVM7 Cohesin subunit SA-1 chr3 Census Yes 1 hippie, biogrid 226 391 66 66 8
STAG2_ENST00000371157 STAG2 Q8N3U4 Cohesin subunit SA-2 chrX Census, Compendium Yes 1 hippie, biogrid 179 330 46 46 3
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 intact, hippie 70 231 30 30 0
STT3A_ENST00000529196 STT3A P46977 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A chr11 Not Cancer Driver No 1 hippie, biogrid 82 27 2 2 1
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 2 hippie, biogrid 35 112 14 14 12
SUB1_ENST00000515355 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 Not Cancer Driver No 1 hippie, biogrid 13 108 6 6 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 intact, hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
SUPT16H SUPT16H Q9Y5B9 FACT complex subunit SPT16 chr14 Not Cancer Driver No 2 hippie, biogrid 147 301 44 44 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie, biogrid 165 572 87 87 0
SUPT6H SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 Not Cancer Driver No 1 hippie, biogrid 222 761 107 107 0
SURF4 SURF4 O15260 Surfeit locus protein 4 chr9 Not Cancer Driver No 1 hippie, biogrid 29 0 0 0 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie, biogrid 83 483 46 46 3
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 Not Cancer Driver No 1 hippie 44 271 18 18 0
SYCP2L SYCP2L Q5T4T6 Synaptonemal complex protein 2-like chr6 Not Cancer Driver No 1 intact, hippie 155 321 46 46 0
TAF13 TAF13 Q15543 Transcription initiation factor TFIID subunit 13 chr1 Not Cancer Driver No 1 hippie, biogrid 11 34 3 3 2
TAF3 TAF3 Q5VWG9 Transcription initiation factor TFIID subunit 3 chr10 Not Cancer Driver No 1 hippie, biogrid 113 750 90 90 0
TAGLN_ENST00000530649 TAGLN Q01995 Transgelin chr11 Not Cancer Driver No 1 hippie 20 94 12 12 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 Census Yes 1 hippie 54 305 53 53 0
TBL3 TBL3 Q12788 Transducin beta-like protein 3 chr16 Not Cancer Driver No 1 hippie, biogrid 82 48 8 8 0
TCEA2 TCEA2 Q15560 Transcription elongation factor A protein 2 chr20 Not Cancer Driver No 1 hippie, biogrid 45 194 40 40 0
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 Census Yes 1 hippie 52 649 52 52 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 141 662 136 136 13
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 Census, Compendium Yes 2 intact, hippie 122 516 93 93 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 1 hippie 28 310 16 16 0
TEX10 TEX10 Q9NXF1 Testis-expressed protein 10 chr9 Not Cancer Driver No 1 hippie, biogrid 115 103 12 12 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
THRA THRA P10827 Thyroid hormone receptor alpha chr17 Not Cancer Driver No 1 hippie 69 207 30 30 2
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 Census Yes 1 hippie 137 955 137 137 0
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 Not Cancer Driver No 1 hippie 87 113 28 28 33
THRSP THRSP Q92748 Thyroid hormone-inducible hepatic protein chr11 Not Cancer Driver No 1 intact, hippie 28 47 7 7 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 Not Cancer Driver No 1 hippie, biogrid 154 367 51 51 0
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 78 412 52 52 0
TNPO1 TNPO1 Q92973 Transportin-1 chr5 Not Cancer Driver No 1 hippie, biogrid 99 68 7 7 0
TOP1 TOP1 P11387 DNA topoisomerase 1 chr20 Census, Compendium Yes 2 hippie, biogrid 93 391 53 53 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 Compendium Yes 2 hippie, biogrid 150 508 59 59 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 Not Cancer Driver No 2 hippie, biogrid 154 543 46 46 0
TOPBP1 TOPBP1 Q92547 DNA topoisomerase 2-binding protein 1 chr3 Not Cancer Driver No 2 hippie, biogrid 169 577 59 59 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 Not Cancer Driver No 1 hippie 149 795 105 105 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 hippie 227 1632 190 190 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 4 intact, hippie 2891 282 1466 1466 83
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 1 intact, hippie 63 4 1 1 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie 67 62 7 7 0
TRAIP TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 Not Cancer Driver No 1 hippie 63 240 33 33 1
TRIB2 TRIB2 Q92519 Tribbles homolog 2 chr2 Not Cancer Driver No 1 hippie 64 43 5 5 0
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRIM29 TRIM29 Q14134 Tripartite motif-containing protein 29 chr11 Not Cancer Driver No 1 hippie 121 351 72 72 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TRIP12_ENST00000283943 TRIP12 Q14669 E3 ubiquitin-protein ligase TRIP12 chr2 Not Cancer Driver No 2 hippie, biogrid 224 845 117 117 4
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie 40 63 11 11 5
TUBB1 TUBB1 Q9H4B7 Tubulin beta-1 chain chr20 Not Cancer Driver No 1 hippie 71 38 4 4 1
TUBG1 TUBG1 P23258 Tubulin gamma-1 chain chr17 Not Cancer Driver No 1 hippie, biogrid 51 44 10 10 3
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 Not Cancer Driver No 1 hippie 61 77 14 14 0
U2SURP U2SURP O15042 U2 snRNP-associated SURP motif-containing protein chr3 Not Cancer Driver No 1 hippie, biogrid 127 757 105 105 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 hippie, biogrid 84 219 33 33 0
UBC UBC P0CG48 Polyubiquitin-C chr12 Not Cancer Driver No 1 intact 97 312 53 53 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 Not Cancer Driver No 1 hippie, biogrid 100 567 77 77 1
UBXN7 UBXN7 O94888 UBX domain-containing protein 7 chr3 Not Cancer Driver No 1 hippie, biogrid 65 327 39 39 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UHRF1_ENST00000616255 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 Not Cancer Driver No 2 hippie, biogrid 97 353 49 49 0
UHRF2 UHRF2 Q96PU4 E3 ubiquitin-protein ligase UHRF2 chr9 Not Cancer Driver No 1 hippie 88 253 22 22 0
UIMC1_ENST00000511320 UIMC1 Q96RL1 BRCA1-A complex subunit RAP80 chr5 Not Cancer Driver No 2 hippie, biogrid 64 609 51 51 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 Not Cancer Driver No 1 hippie 142 588 77 77 0
URB1 URB1 O60287 Nucleolar pre-ribosomal-associated protein 1 chr21 Not Cancer Driver No 1 hippie, biogrid 93 180 2 2 0
URB2 URB2 Q14146 Unhealthy ribosome biogenesis protein 2 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 186 18 2 2 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 Not Cancer Driver No 1 hippie 52 271 44 44 0
USP10_ENST00000219473 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 Not Cancer Driver No 1 hippie 92 425 49 49 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 140 210 28 28 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 59 86 6 6 0
USP36_ENST00000312010 USP36 Q9P275 Ubiquitin carboxyl-terminal hydrolase 36 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 151 718 91 91 0
USP48 USP48 Q86UV5 Ubiquitin carboxyl-terminal hydrolase 48 chr1 Not Cancer Driver No 1 hippie, biogrid 125 178 21 21 0
UTP14A UTP14A Q9BVJ6 U3 small nucleolar RNA-associated protein 14 homolog A chrX Not Cancer Driver No 1 hippie, biogrid 105 629 89 89 0
UTP18 UTP18 Q9Y5J1 U3 small nucleolar RNA-associated protein 18 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 49 250 21 21 0
UTP20 UTP20 O75691 Small subunit processome component 20 homolog chr12 Not Cancer Driver No 1 hippie, biogrid 324 314 35 35 0
UTP3 UTP3 Q9NQZ2 Something about silencing protein 10 chr4 Not Cancer Driver No 1 hippie, biogrid 41 303 25 25 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 142 117 36 36 133
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VRK1 VRK1 Q99986 Serine/threonine-protein kinase VRK1 chr14 Not Cancer Driver No 2 hippie, biogrid 52 80 9 9 0
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 Not Cancer Driver No 1 hippie 65 180 18 18 0
WDHD1 WDHD1 O75717 WD repeat and HMG-box DNA-binding protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 100 474 31 31 0
WDR36 WDR36 Q8NI36 WD repeat-containing protein 36 chr5 Not Cancer Driver No 1 hippie, biogrid 140 89 11 11 2
WDR43 WDR43 Q15061 WD repeat-containing protein 43 chr2 Not Cancer Driver No 1 hippie, biogrid 57 216 18 18 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 60 288 33 33 0
WIZ_ENST00000263381 WIZ O95785-2 Isoform 2 of Protein Wiz chr19 Not Cancer Driver No 1 hippie, biogrid 148 651 135 135 0
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 Census, Compendium Yes 2 intact, hippie 164 373 41 41 2
WRNIP1 WRNIP1 Q96S55 ATPase WRNIP1 chr6 Not Cancer Driver No 1 hippie, biogrid 50 292 7 7 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
XPC XPC Q01831 DNA repair protein complementing XP-C cells chr3 Census, Compendium Yes 3 hippie, biogrid 88 479 48 48 2
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 Not Cancer Driver No 5 intact, hippie, biogrid 85 426 53 53 1
XRCC4 XRCC4 Q13426 DNA repair protein XRCC4 chr5 Not Cancer Driver No 1 hippie, biogrid 47 171 31 31 3
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 Not Cancer Driver No 6 intact, hippie, biogrid 87 118 11 11 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 5 intact, hippie, biogrid 66 140 12 12 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
YARS YARS1 P54577 Tyrosine--tRNA ligase, cytoplasmic chr1 Not Cancer Driver No 1 intact 62 109 9 9 3
YJU2 YJU2 Q9BW85 Splicing factor YJU2 chr19 Not Cancer Driver No 1 hippie 29 233 13 13 0
YTHDC1_ENST00000344157 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 137 597 117 117 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 intact, hippie 26 77 9 9 2
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 30 81 10 10 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 Not Cancer Driver No 2 hippie, biogrid 37 336 26 26 2
ZBTB10 ZBTB10 Q96DT7 Zinc finger and BTB domain-containing protein 10 chr8 Not Cancer Driver No 1 hippie, biogrid 59 531 32 32 0
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 Census, Compendium Yes 1 hippie 131 268 50 50 1
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 78 236 25 25 0
ZBTB21 ZBTB21 Q9ULJ3 Zinc finger and BTB domain-containing protein 21 chr21 Not Cancer Driver No 1 hippie, biogrid 136 645 75 75 0
ZBTB24 ZBTB24 O43167 Zinc finger and BTB domain-containing protein 24 chr6 Not Cancer Driver No 1 hippie 71 383 43 43 1
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 Not Cancer Driver No 1 hippie 60 285 30 30 0
ZBTB9 ZBTB9 Q96C00 Zinc finger and BTB domain-containing protein 9 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 61 256 40 40 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 Census, Compendium Yes 2 hippie, biogrid 246 831 200 200 8
ZKSCAN4 ZKSCAN4 Q969J2 Zinc finger protein with KRAB and SCAN domains 4 chr6 Not Cancer Driver No 1 hippie, biogrid 43 303 23 23 0
ZMAT2 ZMAT2 Q96NC0 Zinc finger matrin-type protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 24 148 19 19 0
ZMYM3 ZMYM3 Q14202 Zinc finger MYM-type protein 3 chrX Census Yes 1 hippie, biogrid 203 538 90 90 0
ZMYM4 ZMYM4 Q5VZL5 Zinc finger MYM-type protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 159 660 53 53 0
ZNF106 ZNF106 Q9H2Y7 Zinc finger protein 106 chr15 Not Cancer Driver No 1 hippie, biogrid 179 1491 137 137 0
ZNF136 ZNF136 P52737 Zinc finger protein 136 chr19 Not Cancer Driver No 1 hippie, biogrid 80 96 15 15 0
ZNF146_ENST00000443387 ZNF146 Q15072 Zinc finger protein OZF chr19 Not Cancer Driver No 1 hippie, biogrid 46 44 5 5 0
ZNF148_ENST00000485866 ZNF148 Q9UQR1 Zinc finger protein 148 chr3 Compendium Yes 1 hippie, biogrid 125 600 88 88 0
ZNF24 ZNF24 P17028 Zinc finger protein 24 chr18 Not Cancer Driver No 1 hippie, biogrid 47 187 29 29 0
ZNF281_ENST00000367353 ZNF281 Q9Y2X9 Zinc finger protein 281 chr1 Not Cancer Driver No 1 hippie, biogrid 92 709 67 67 0
ZNF292 ZNF292 O60281 Zinc finger protein 292 chr6 Not Cancer Driver No 1 hippie, biogrid 340 1483 170 170 0
ZNF330 ZNF330 Q9Y3S2 Zinc finger protein 330 chr4 Not Cancer Driver No 1 hippie, biogrid 44 127 19 19 0
ZNF362_ENST00000373428 ZNF362 Q5T0B9 Zinc finger protein 362 chr1 Not Cancer Driver No 1 hippie, biogrid 65 281 36 36 0
ZNF365_ENST00000395251 ZNF365 Q70YC4 Talanin chr10 Not Cancer Driver No 1 hippie 47 74 22 22 0
ZNF384 ZNF384 Q8TF68 Zinc finger protein 384 chr12 Census Yes 1 hippie, biogrid 63 403 44 44 0
ZNF423 ZNF423 Q2M1K9 Zinc finger protein 423 chr16 Not Cancer Driver No 1 hippie 340 416 108 108 2
ZNF451 ZNF451 Q9Y4E5 E3 SUMO-protein ligase ZNF451 chr6 Not Cancer Driver No 1 hippie, biogrid 169 191 25 25 0
ZNF512 ZNF512 Q96ME7 Zinc finger protein 512 chr2 Not Cancer Driver No 1 hippie, biogrid 76 280 42 42 0
ZNF512B ZNF512B Q96KM6 Zinc finger protein 512B chr20 Not Cancer Driver No 1 hippie, biogrid 101 694 83 83 0
ZNF644_ENST00000370440 ZNF644 Q9H582 Zinc finger protein 644 chr1 Not Cancer Driver No 1 hippie, biogrid 176 870 108 108 4
ZNF711_ENST00000373165 ZNF711 Q9Y462 Zinc finger protein 711 chrX Not Cancer Driver No 1 hippie, biogrid 192 357 75 75 1
ZNF746_ENST00000340622 ZNF746 Q6NUN9 Zinc finger protein 746 chr7 Not Cancer Driver No 1 hippie 93 436 56 56 0
ZRANB2 ZRANB2 O95218 Zinc finger Ran-binding domain-containing protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 56 257 44 44 0
ZSCAN21 ZSCAN21 Q9Y5A6 Zinc finger and SCAN domain-containing protein 21 chr7 Not Cancer Driver No 1 hippie, biogrid 68 252 38 38 0