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PARK7_ENST00000377488 ,PARK7 ,Q99497
  • Uniprot Accession= Q99497
  • Ensembl Transcript= ENST00000377488.5
  • Uniprot Name= PARK7
  • Name= Parkinson disease protein 7
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 90
  • Number of Interaction partner in biogrid: 159
  • Number of Interaction partner in hippie: 326
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
A2M A2M P01023 Alpha-2-macroglobulin chr12 Not Cancer Driver No 1 hippie 260 144 22 22 0
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 42 51 2 2 0
ACO2 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 94 172 19 19 5
ACOT1 ACOT1 Q86TX2 Acyl-coenzyme A thioesterase 1 chr14 Not Cancer Driver No 1 hippie, biogrid 28 22 0 0 0
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ACTN1_ENST00000193403 ACTN1 P12814 Alpha-actinin-1 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 108 195 30 30 6
ADA ADA P00813 Adenosine deaminase chr20 Not Cancer Driver No 1 hippie, biogrid 50 44 9 9 27
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AK3 AK3 Q9UIJ7 GTP:AMP phosphotransferase AK3, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 23 33 3 3 0
ALYREF ALYREF Q86V81 THO complex subunit 4 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 32 223 26 26 0
ANP32A ANP32A P39687 Acidic leucine-rich nuclear phosphoprotein 32 family member A chr15 Not Cancer Driver No 1 hippie, biogrid 31 165 21 21 0
ANP32B ANP32B Q92688 Acidic leucine-rich nuclear phosphoprotein 32 family member B chr9 Not Cancer Driver No 1 hippie, biogrid 22 117 12 12 0
ANXA5 ANXA5 P08758 Annexin A5 chr4 Not Cancer Driver No 1 hippie, biogrid 50 33 5 5 0
ANXA7 ANXA7 P20073 Annexin A7 chr10 Not Cancer Driver No 1 hippie, biogrid 68 215 37 37 0
AP2B1_ENST00000621914 AP2B1 P63010 AP-2 complex subunit beta chr17 Not Cancer Driver No 1 hippie 85 95 12 12 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie 128 418 71 71 17
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARCN1 ARCN1 P48444 Coatomer subunit delta chr11 Not Cancer Driver No 1 hippie, biogrid 46 194 24 24 0
ARF1_ENST00000272102 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 30 4 2 2 2
ARIH2 ARIH2 O95376 E3 ubiquitin-protein ligase ARIH2 chr3 Not Cancer Driver No 1 hippie 64 85 11 11 0
ATP5IF1 ATP5IF1 Q9UII2 ATPase inhibitor, mitochondrial chr1 Not Cancer Driver No 1 hippie 8 85 7 7 0
ATP5PF_ENST00000400090 ATP5PF P18859 ATP synthase-coupling factor 6, mitochondrial chr21 Not Cancer Driver No 1 hippie 14 15 1 1 0
BABAM1_ENST00000601043 BABAM1 Q9NWV8 BRISC and BRCA1-A complex member 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 35 113 14 14 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 2 hippie, biogrid 29 195 9 9 0
BASP1_ENST00000616743 BASP1 P80723 Brain acid soluble protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 39 227 39 39 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 Census Yes 1 hippie 30 39 2 2 0
BBS1 BBS1 Q8NFJ9 Bardet-Biedl syndrome 1 protein chr11 Not Cancer Driver No 2 intact, hippie 69 99 14 14 12
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 Not Cancer Driver No 1 hippie 29 55 3 3 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 Census, Compendium Yes 1 hippie, biogrid 421 899 408 408 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 43 123 17 17 0
C1orf198 C1orf198 Q9H425 Uncharacterized protein C1orf198 chr1 Not Cancer Driver No 1 hippie, biogrid 40 303 36 36 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie, biogrid 19 115 15 15 7
CALR CALR P27797 Calreticulin chr19 Census Yes 1 hippie, biogrid 45 245 31 31 0
CAMK1 CAMK1 Q14012 Calcium/calmodulin-dependent protein kinase type 1 chr3 Not Cancer Driver No 1 hippie 40 31 1 1 0
CAMKK1_ENST00000348335 CAMKK1 Q8N5S9 Calcium/calmodulin-dependent protein kinase kinase 1 chr17 Not Cancer Driver No 1 intact, hippie 82 246 32 32 0
CAMKK2 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 Not Cancer Driver No 1 hippie 65 281 35 35 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 hippie 142 106 12 12 1
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 Not Cancer Driver No 1 intact, hippie, biogrid 41 36 2 2 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 29 54 9 9 0
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 68 278 40 40 0
CFL1_ENST00000308162 CFL1 P23528 Cofilin-1 chr11 Not Cancer Driver No 1 hippie, biogrid 21 4 0 0 0
CFL2_ENST00000341223 CFL2 Q9Y281 Cofilin-2 chr14 Not Cancer Driver No 1 hippie, biogrid 25 0 0 0 1
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 2 intact, hippie 287 145 18 18 151
CHD2 CHD2 O14647 Chromodomain-helicase-DNA-binding protein 2 chr15 Census, Compendium Yes 1 intact, hippie 222 1051 136 136 2
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 hippie 419 974 177 177 6
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CHTOP_ENST00000368694 CHTOP Q9Y3Y2 Chromatin target of PRMT1 protein chr1 Not Cancer Driver No 1 hippie, biogrid 36 244 34 34 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 Not Cancer Driver No 1 hippie 22 42 4 4 1
CLIC1_ENST00000375779 CLIC1 O00299 Chloride intracellular channel protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 32 27 5 5 0
CLIC4 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 24 49 4 4 0
CMPK1 CMPK1 P30085-3 Isoform 3 of UMP-CMP kinase chr1 Not Cancer Driver No 1 hippie, biogrid 23 30 3 3 0
COPE_ENST00000262812 COPE O14579 Coatomer subunit epsilon chr19 Not Cancer Driver No 1 hippie 29 47 6 6 0
CPSF6_ENST00000435070 CPSF6 Q16630 Cleavage and polyadenylation specificity factor subunit 6 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 85 484 75 75 0
CRYZ_ENST00000340866 CRYZ Q08257 Quinone oxidoreductase chr1 Not Cancer Driver No 1 hippie, biogrid 49 0 0 0 0
CSN1S1 CSN1S1 P47710 Alpha-S1-casein chr4 Not Cancer Driver No 1 hippie 31 109 16 16 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 Census, Compendium Yes 2 intact, hippie 106 549 81 81 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 intact, hippie, biogrid 84 510 73 73 0
DDAH1 DDAH1 O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 28 44 3 3 0
DDAH2_ENST00000375787 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 Not Cancer Driver No 1 hippie, biogrid 24 96 6 6 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie, biogrid 49 34 8 8 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX Not Cancer Driver No 1 hippie, biogrid 62 145 29 29 24
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 67 17 0 0 10
DNAJB11_ENST00000265028 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie, biogrid 52 141 21 21 2
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 Not Cancer Driver No 1 hippie, biogrid 60 131 17 17 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 Not Cancer Driver No 1 hippie, biogrid 67 212 23 23 7
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 intact, hippie 138 270 43 43 22
DSTN DSTN P60981 Destrin chr20 Not Cancer Driver No 1 hippie, biogrid 18 0 0 0 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 Not Cancer Driver No 1 hippie 31 7 0 0 0
DUSP12 DUSP12 Q9UNI6 Dual specificity protein phosphatase 12 chr1 Not Cancer Driver No 1 hippie 33 30 1 1 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 Not Cancer Driver No 1 hippie 34 15 5 5 0
DUSP2 DUSP2 Q05923 Dual specificity protein phosphatase 2 chr2 Not Cancer Driver No 1 hippie 24 23 3 3 0
DUSP28_ENST00000343217 DUSP28 Q4G0W2 Dual specificity phosphatase 28 chr2 Not Cancer Driver No 1 hippie 11 55 4 4 0
DUSP4 DUSP4 Q13115 Dual specificity protein phosphatase 4 chr8 Not Cancer Driver No 1 hippie 43 63 9 9 0
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 Not Cancer Driver No 1 hippie 43 39 3 3 4
DUSP9 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX Not Cancer Driver No 1 hippie 40 109 12 12 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EEF1G EEF1G P26641 Elongation factor 1-gamma chr11 Not Cancer Driver No 1 hippie, biogrid 44 66 5 5 0
EEF2 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 111 78 14 14 1
EFCAB6 EFCAB6 Q5THR3 EF-hand calcium-binding domain-containing protein 6 chr22 Not Cancer Driver No 1 hippie 262 356 77 77 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF3B_ENST00000397011 EIF3B P55884 Eukaryotic translation initiation factor 3 subunit B chr7 Not Cancer Driver No 1 hippie, biogrid 89 226 4 4 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 Not Cancer Driver No 1 hippie 50 57 6 6 1
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 Not Cancer Driver No 1 hippie, biogrid 30 17 3 3 0
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 2 hippie, biogrid 51 21 2 2 0
EPB41L5 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 Not Cancer Driver No 1 intact, hippie 97 312 45 45 0
FADD FADD Q13158 FAS-associated death domain protein chr11 Not Cancer Driver No 1 hippie 26 45 10 10 1
FAHD2A FAHD2A Q96GK7 Fumarylacetoacetate hydrolase domain-containing protein 2A chr2 Not Cancer Driver No 1 hippie, biogrid 39 8 2 2 0
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact 113 162 28 28 0
FKBP3_ENST00000396062 FKBP3 Q00688 Peptidyl-prolyl cis-trans isomerase FKBP3 chr14 Not Cancer Driver No 1 hippie, biogrid 27 131 17 17 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 intact, hippie 92 70 13 13 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 Not Cancer Driver No 1 hippie 85 537 73 73 0
GATAD2B_ENST00000634544 GATAD2B Q8WXI9 Transcriptional repressor p66-beta chr1 Not Cancer Driver No 1 intact, hippie 76 510 67 67 0
GCSH GCSH P23434 Glycine cleavage system H protein, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 15 25 0 0 0
GEMIN4 GEMIN4 P57678 Gem-associated protein 4 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 101 24 1 1 0
GLRX5 GLRX5 Q86SX6 Glutaredoxin-related protein 5, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 7 23 0 0 2
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 1 hippie 56 263 34 34 0
GPX4_ENST00000616066 GPX4 P36969 Phospholipid hydroperoxide glutathione peroxidase chr19 Not Cancer Driver No 1 hippie 14 0 0 0 0
GRHPR GRHPR Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase chr9 Not Cancer Driver No 1 hippie, biogrid 31 36 4 4 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 Not Cancer Driver No 1 hippie, biogrid 32 0 0 0 0
HADHA HADHA P40939 Trifunctional enzyme subunit alpha, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie, biogrid 72 19 2 2 5
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 intact, hippie 47 135 10 10 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 intact, hippie 46 145 14 14 0
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 Not Cancer Driver No 1 hippie 59 622 57 57 0
HDHD3 HDHD3 Q9BSH5 Haloacid dehalogenase-like hydrolase domain-containing protein 3 chr9 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 0
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 Not Cancer Driver No 2 hippie, biogrid 11 6 0 0 6
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 10 29 2 2 0
HIPK1_ENST00000426820 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 Not Cancer Driver No 1 hippie 158 565 89 89 0
HMGA1 HMGA1 P17096 High mobility group protein HMG-I/HMG-Y chr6 Census Yes 1 hippie, biogrid 6 107 6 6 0
HMGN1 HMGN1 P05114 Non-histone chromosomal protein HMG-14 chr21 Not Cancer Driver No 1 hippie, biogrid 12 100 12 12 0
HNRNPA1L2 HNRNPA1L2 Q32P51 Heterogeneous nuclear ribonucleoprotein A1-like 2 chr13 Not Cancer Driver No 1 hippie, biogrid 29 235 23 23 0
HNRNPDL HNRNPDL O14979 Heterogeneous nuclear ribonucleoprotein D-like chr4 Not Cancer Driver No 1 intact, hippie, biogrid 51 297 36 36 2
HRNR HRNR Q86YZ3 Hornerin chr1 Not Cancer Driver No 1 intact, hippie, biogrid 612 2767 601 601 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 intact, hippie, biogrid 27 15 3 3 11
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie 80 351 24 24 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie 73 282 35 35 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 67 283 26 26 2
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 336 666 69 69 2
IDH2 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 Census, Compendium Yes 1 hippie, biogrid 74 59 1 1 7
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
ILF2 ILF2 Q12905 Interleukin enhancer-binding factor 2 chr1 Not Cancer Driver No 1 hippie, biogrid 36 92 9 9 0
IMPA2 IMPA2 O14732 Inositol monophosphatase 2 chr18 Not Cancer Driver No 1 hippie, biogrid 44 21 1 1 0
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 70 6 1 1 0
INS INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 15 5 1 1 22
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 intact, hippie 183 351 35 35 0
IQSEC1_ENST00000273221 IQSEC1 Q6DN90 IQ motif and SEC7 domain-containing protein 1 chr3 Not Cancer Driver No 1 intact, hippie 141 610 97 97 2
ISOC2_ENST00000425675 ISOC2 Q96AB3 Isochorismatase domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 24 8 0 0 0
ITPA ITPA Q9BY32 Inosine triphosphate pyrophosphatase chr20 Not Cancer Driver No 1 hippie, biogrid 21 10 1 1 1
ITPR3 ITPR3 Q14573 Inositol 1,4,5-trisphosphate receptor type 3 chr6 Not Cancer Driver No 1 hippie 336 385 44 44 0
JUND JUND P17535 Transcription factor JunD chr19 Not Cancer Driver No 1 hippie 21 313 19 19 0
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 1 intact, hippie 253 633 106 106 1
KRTAP9-2 KRTAP9-2 Q9BYQ4 Keratin-associated protein 9-2 chr17 Not Cancer Driver No 1 hippie 37 0 0 0 0
LACTB2 LACTB2 Q53H82 Endoribonuclease LACTB2 chr8 Not Cancer Driver No 1 hippie, biogrid 34 21 1 1 0
LDHAL6B LDHAL6B Q9BYZ2 L-lactate dehydrogenase A-like 6B chr15 Not Cancer Driver No 1 intact, hippie 54 17 2 2 0
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie, biogrid 40 9 0 0 0
LDHB_ENST00000350669 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 47 15 2 2 11
LGALS3 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 15 133 6 6 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 88 687 81 81 0
LIN37 LIN37 Q96GY3 Protein lin-37 homolog chr19 Not Cancer Driver No 1 hippie 34 239 34 34 0
LIN54 LIN54 Q6MZP7 Protein lin-54 homolog chr4 Not Cancer Driver No 1 hippie 61 440 31 31 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LYPLA1 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 19 12 2 2 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 Not Cancer Driver No 1 hippie 332 1947 278 278 0
MAP2K2 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 Census Yes 1 intact, hippie, biogrid 58 105 14 14 4
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 Not Cancer Driver No 1 hippie 197 242 29 29 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 104 333 66 66 6
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 Not Cancer Driver No 1 hippie 116 276 41 41 0
MAP4K5 MAP4K5 Q9Y4K4 Mitogen-activated protein kinase kinase kinase kinase 5 chr14 Not Cancer Driver No 1 hippie 69 236 23 23 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 Not Cancer Driver No 1 hippie 79 444 40 40 1
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 Not Cancer Driver No 1 hippie 51 101 12 12 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 14 328 14 14 0
MBD3 MBD3 O95983 Methyl-CpG-binding domain protein 3 chr19 Not Cancer Driver No 1 intact, hippie 50 246 46 46 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MDH2 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 39 8 1 1 3
MIF MIF P14174 Macrophage migration inhibitory factor chr22 Not Cancer Driver No 2 hippie, biogrid 4 0 0 0 0
MPST_ENST00000341116 MPST P25325 3-mercaptopyruvate sulfurtransferase chr22 Not Cancer Driver No 1 hippie, biogrid 20 72 8 8 0
MRPS18B MRPS18B Q9Y676 28S ribosomal protein S18b, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 31 112 12 12 0
MRPS9 MRPS9 P82933 28S ribosomal protein S9, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie, biogrid 49 75 9 9 0
MSRB1_ENST00000622125 MSRB1 Q9NZV6 Methionine-R-sulfoxide reductase B1 chr16 Not Cancer Driver No 1 hippie 18 28 5 5 0
MSRB2 MSRB2 Q9Y3D2 Methionine-R-sulfoxide reductase B2, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 17 65 6 6 0
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 Not Cancer Driver No 1 intact, hippie 92 327 42 42 0
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 Not Cancer Driver No 1 intact, hippie 78 283 32 32 0
MTHFD1 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 Not Cancer Driver No 1 intact, hippie, biogrid 103 129 11 11 6
MTRF1 MTRF1 O75570 Peptide chain release factor 1, mitochondrial chr13 Not Cancer Driver No 1 hippie 50 71 9 9 0
MYCBP MYCBP Q99417 c-Myc-binding protein chr1 Not Cancer Driver No 1 hippie, biogrid 8 54 4 4 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYH11_ENST00000300036 MYH11 P35749 Myosin-11 chr16 Census, Compendium Yes 1 hippie, biogrid 353 1180 201 201 2
MYL12A_ENST00000217652 MYL12A P19105 Myosin regulatory light chain 12A chr18 Not Cancer Driver No 1 intact, hippie, biogrid 19 70 13 13 0
MYLK4 MYLK4 Q86YV6 Myosin light chain kinase family member 4 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 67 77 14 14 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NACA_ENST00000356769 NACA Q13765 Nascent polypeptide-associated complex subunit alpha chr12 Census Yes 1 hippie, biogrid 37 143 26 26 0
NDUFA4 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 hippie 14 4 0 0 0
NDUFAB1_ENST00000007516 NDUFAB1 O14561 Acyl carrier protein, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
NDUFS3 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 Not Cancer Driver No 1 hippie 34 26 3 3 2
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie, biogrid 150 711 79 79 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 35 23 0 0 0
NENF NENF Q9UMX5 Neudesin chr1 Not Cancer Driver No 1 hippie, biogrid 15 98 7 7 0
NGB NGB Q9NPG2 Neuroglobin chr14 Not Cancer Driver No 1 hippie 20 3 0 0 0
NHLRC2 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 74 103 12 12 0
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 230 881 150 150 0
NIT2 NIT2 Q9NQR4 Omega-amidase NIT2 chr3 Not Cancer Driver No 1 hippie, biogrid 47 0 0 0 0
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX Census, Compendium Yes 1 hippie 101 349 64 64 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 Not Cancer Driver No 1 hippie, biogrid 207 201 33 33 0
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 29 249 22 22 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 Compendium Yes 1 hippie, biogrid 146 211 31 31 0
NUP43 NUP43 Q8NFH3 Nucleoporin Nup43 chr6 Not Cancer Driver No 1 intact, hippie 47 103 9 9 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OAT OAT P04181 Ornithine aminotransferase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 52 17 0 0 27
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 2 intact, hippie 31 33 2 2 0
OTUD7B OTUD7B Q6GQQ9 OTU domain-containing protein 7B chr1 Not Cancer Driver No 1 hippie 124 537 87 87 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 intact, hippie, biogrid 100 317 55 55 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 4 intact, hippie 11 30 0 0 5
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 intact, hippie 30 22 3 3 1
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PDHB PDHB P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie, biogrid 32 4 0 0 2
PDIA4 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie, biogrid 81 147 22 22 0
PDIA6_ENST00000272227 PDIA6 Q15084 Protein disulfide-isomerase A6 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 55 82 11 11 0
PDP1_ENST00000297598 PDP1 Q9P0J1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 64 96 9 9 0
PEBP1 PEBP1 P30086 Phosphatidylethanolamine-binding protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 23 76 13 13 0
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 16 7 1 1 3
PGAM1 PGAM1 P18669 Phosphoglycerate mutase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 20 70 5 5 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX Not Cancer Driver No 1 hippie, biogrid 61 40 5 5 9
PGLS PGLS O95336 6-phosphogluconolactonase chr19 Not Cancer Driver No 1 hippie, biogrid 20 36 4 4 0
PGM1_ENST00000371084 PGM1 P36871 Phosphoglucomutase-1 chr1 Not Cancer Driver No 1 hippie, biogrid 62 31 3 3 13
PHOSPHO1_ENST00000310544 PHOSPHO1 Q8TCT1 Phosphoethanolamine/phosphocholine phosphatase chr17 Not Cancer Driver No 1 intact, hippie 14 18 0 0 0
PIAS2 PIAS2 O75928 E3 SUMO-protein ligase PIAS2 chr18 Not Cancer Driver No 1 hippie 78 209 28 28 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PIR_ENST00000380420 PIR O00625 Pirin chrX Not Cancer Driver No 1 hippie, biogrid 29 185 16 16 0
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 Not Cancer Driver No 1 hippie 24 155 12 12 1
PKD2 PKD2 Q13563 Polycystin-2 chr4 Not Cancer Driver No 1 intact 113 375 35 35 10
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie, biogrid 78 58 13 13 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PML PML P29590 Protein PML chr15 Census, Compendium Yes 1 hippie 112 312 34 34 0
PNN PNN Q9H307 Pinin chr14 Not Cancer Driver No 1 hippie, biogrid 94 700 90 90 0
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 36 94 13 13 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 Not Cancer Driver No 2 hippie, biogrid 11 24 3 3 0
PPIB PPIB P23284 Peptidyl-prolyl cis-trans isomerase B chr15 Not Cancer Driver No 1 hippie, biogrid 28 16 1 1 1
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 Not Cancer Driver No 1 hippie, biogrid 65 243 31 31 0
PPM1D PPM1D O15297 Protein phosphatase 1D chr17 Census, Compendium Yes 1 hippie 54 370 32 32 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 Not Cancer Driver No 1 intact, hippie 107 821 89 89 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 intact, hippie 179 0 0 0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 Not Cancer Driver No 1 intact, hippie 72 17 1 1 0
PPP2R2C_ENST00000382599 PPP2R2C Q9Y2T4 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform chr4 Not Cancer Driver No 1 hippie 78 78 13 13 0
PPTC7 PPTC7 Q8NI37 Protein phosphatase PTC7 homolog chr12 Not Cancer Driver No 1 hippie 32 36 2 2 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 Not Cancer Driver No 1 hippie, biogrid 24 30 4 4 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 23 23 3 3 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 Not Cancer Driver No 3 hippie, biogrid 22 0 0 0 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 46 13 4 4 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRKCSH_ENST00000589838 PRKCSH P14314 Glucosidase 2 subunit beta chr19 Not Cancer Driver No 1 hippie, biogrid 68 320 41 41 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 intact, hippie, biogrid 70 116 11 11 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 Compendium Yes 1 hippie, biogrid 118 246 34 34 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRPF4 PRPF4 O43172 U4/U6 small nuclear ribonucleoprotein Prp4 chr9 Not Cancer Driver No 1 hippie, biogrid 61 152 15 15 2
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PTBP1_ENST00000349038 PTBP1 P26599 Polypyrimidine tract-binding protein 1 chr19 Not Cancer Driver No 1 intact, hippie 74 154 17 17 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 505 76 4 4 41
PTMS_ENST00000309083 PTMS P20962 Parathymosin chr12 Not Cancer Driver No 1 hippie, biogrid 10 102 10 10 0
PYCR1_ENST00000329875 PYCR1 P32322 Pyrroline-5-carboxylate reductase 1, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 31 67 10 10 9
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 83 533 70 70 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 Not Cancer Driver No 1 hippie, biogrid 16 38 2 2 0
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 Not Cancer Driver No 1 hippie 34 13 0 0 0
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 Not Cancer Driver No 1 hippie 73 413 30 30 0
RBBP4 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 Not Cancer Driver No 1 hippie 53 169 23 23 0
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX Not Cancer Driver No 1 intact, hippie 67 138 19 19 0
RBM8A_ENST00000632555 RBM8A Q9Y5S9 RNA-binding protein 8A chr1 Not Cancer Driver No 1 hippie, biogrid 35 135 32 32 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 hippie 137 417 61 61 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie, biogrid 119 232 34 34 3
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 Not Cancer Driver No 1 intact, hippie 111 855 96 96 0
RNF112 RNF112 Q9ULX5 RING finger protein 112 chr17 Not Cancer Driver No 1 intact, hippie 86 168 26 26 0
RNPS1_ENST00000301730 RNPS1 Q15287 RNA-binding protein with serine-rich domain 1 chr16 Not Cancer Driver No 1 hippie, biogrid 30 305 30 30 0
SAP18_ENST00000607003 SAP18 O00422 Histone deacetylase complex subunit SAP18 chr13 Not Cancer Driver No 1 hippie, biogrid 18 99 14 14 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 Not Cancer Driver No 1 hippie 7 122 6 6 0
SELENOW_ENST00000612212 SELENOW P63302 Selenoprotein W chr19 Not Cancer Driver No 1 hippie 9 0 0 0 0
SEPHS2 SEPHS2 Q99611 Selenide, water dikinase 2 chr16 Not Cancer Driver No 1 hippie 48 104 2 2 0
SERBP1 SERBP1 Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein chr1 Not Cancer Driver No 1 hippie, biogrid 53 408 53 53 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 Census Yes 1 hippie 59 595 48 48 0
SH3GL3_ENST00000427482 SH3GL3 Q99963 Endophilin-A3 chr15 Not Cancer Driver No 1 hippie 88 83 23 23 0
SLC18A2_ENST00000644641 SLC18A2 Q05940 Synaptic vesicular amine transporter chr10 Not Cancer Driver No 1 hippie 105 23 7 7 1
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 Not Cancer Driver No 1 intact, hippie 271 1573 232 232 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 1 intact, hippie 64 141 35 35 3
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 1 hippie 21 107 13 13 5
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 4 hippie, biogrid 16 93 9 9 79
SPATA2L SPATA2L Q8IUW3 Spermatogenesis-associated protein 2-like protein chr16 Not Cancer Driver No 1 intact, hippie 32 167 12 12 0
SPINDOC SPINDOC Q9BUA3 Spindlin interactor and repressor of chromatin-binding protein chr11 Not Cancer Driver No 1 intact, hippie 56 364 54 54 0
SPR SPR P35270 Sepiapterin reductase chr2 Not Cancer Driver No 1 hippie, biogrid 23 19 4 4 2
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 Not Cancer Driver No 1 hippie 124 357 43 43 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 27 0 0 0 6
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 Not Cancer Driver No 1 hippie, biogrid 15 149 15 15 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 35 112 14 14 12
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie, biogrid 9 69 6 6 0
TAB1 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 81 232 34 34 0
TALDO1 TALDO1 P37837 Transaldolase chr11 Not Cancer Driver No 1 hippie, biogrid 51 31 4 4 0
TDP2 TDP2 O95551 Tyrosyl-DNA phosphodiesterase 2 chr6 Not Cancer Driver No 1 hippie 55 80 10 10 0
THEM4 THEM4 Q5T1C6 Acyl-coenzyme A thioesterase THEM4 chr1 Not Cancer Driver No 1 hippie, biogrid 19 14 0 0 0
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 Census Yes 1 hippie, biogrid 137 955 137 137 0
TIA1 TIA1 P31483 Cytotoxic granule associated RNA binding protein TIA1 chr2 Not Cancer Driver No 1 intact, hippie 39 130 12 12 2
TIFAB TIFAB Q6ZNK6 TRAF-interacting protein with FHA domain-containing protein B chr5 Not Cancer Driver No 1 intact, hippie 32 26 7 7 0
TKT_ENST00000462138 TKT P29401 Transketolase chr3 Not Cancer Driver No 1 hippie, biogrid 66 86 7 7 1
TMOD2 TMOD2 Q9NZR1 Tropomodulin-2 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 33 216 22 22 0
TMOD3 TMOD3 Q9NYL9 Tropomodulin-3 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 40 190 24 24 0
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 Not Cancer Driver No 1 hippie 55 174 17 17 0
TOR1A TOR1A O14656 Torsin-1A chr9 Not Cancer Driver No 1 hippie 33 0 0 0 3
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TPI1_ENST00000396705 TPI1 P60174 Triosephosphate isomerase chr12 Not Cancer Driver No 2 hippie, biogrid 40 15 2 2 7
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 Not Cancer Driver No 1 intact, hippie, biogrid 33 234 29 29 8
TPM3 TPM3 P06753 Tropomyosin alpha-3 chain chr1 Census Yes 2 intact, hippie, biogrid 35 230 27 27 21
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 67 62 7 7 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 74 110 11 11 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 Census, Compendium Yes 1 intact, hippie, biogrid 120 537 61 61 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 intact, hippie, biogrid 87 430 41 41 0
TXN TXN P10599 Thioredoxin chr9 Not Cancer Driver No 1 hippie, biogrid 6 0 0 0 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 hippie 78 191 28 28 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 hippie 84 219 33 33 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 intact, hippie 16 16 3 3 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UCHL1 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 Not Cancer Driver No 1 hippie, biogrid 33 34 7 7 4
UNK UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 79 511 46 46 0
USP19_ENST00000398888 USP19 O94966 Ubiquitin carboxyl-terminal hydrolase 19 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 161 539 68 68 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 hippie 38 36 4 4 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 intact, hippie 142 117 36 36 133
VPS29_ENST00000549578 VPS29 Q9UBQ0 Vacuolar protein sorting-associated protein 29 chr12 Not Cancer Driver No 1 intact, hippie 24 0 0 0 0
WBP11 WBP11 Q9Y2W2 WW domain-binding protein 11 chr12 Not Cancer Driver No 1 hippie, biogrid 86 606 79 79 0
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 Not Cancer Driver No 1 intact, hippie 25 7 1 1 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 intact, hippie, biogrid 22 109 4 4 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 intact, hippie, biogrid 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 intact, hippie, biogrid 30 81 10 10 0
ZBTB2 ZBTB2 Q8N680 Zinc finger and BTB domain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 75 216 30 30 0