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ORC1_ENST00000371566 ,ORC1 ,Q13415
  • Uniprot Accession= Q13415
  • Ensembl Transcript= ENST00000371566.1
  • Uniprot Name= ORC1
  • Name= Origin recognition complex subunit 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 33
  • Number of Interaction partner in biogrid: 6
  • Number of Interaction partner in hippie: 80
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
AL662899.2_ENST00000375880 CSNK2B Q5SRQ3 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie, biogrid 21 30 1 1 0
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 Not Cancer Driver No 1 intact, hippie 21 116 12 12 0
CCNA1 CCNA1 P78396 Cyclin-A1 chr13 Not Cancer Driver No 1 intact, hippie 112 82 21 21 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 Not Cancer Driver No 4 hippie, biogrid 45 186 19 19 0
CDC45_ENST00000407835 CDC45 O75419 Cell division control protein 45 homolog chr22 Not Cancer Driver No 1 hippie 73 66 16 16 5
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 Not Cancer Driver No 5 intact, hippie 57 170 15 15 1
CDC7 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 Not Cancer Driver No 1 hippie 72 185 24 24 0
CDIPT_ENST00000569956 CDIPT O14735 CDP-diacylglycerol--inositol 3-phosphatidyltransferase chr16 Not Cancer Driver No 1 intact, hippie 21 0 0 0 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 Not Cancer Driver No 1 hippie 40 1 0 0 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 24 0 0 0 0
CDT1 CDT1 Q9H211 DNA replication factor Cdt1 chr16 Not Cancer Driver No 1 hippie 60 377 35 35 5
CHMP1B CHMP1B Q7LBR1 Charged multivesicular body protein 1b chr18 Not Cancer Driver No 1 intact, hippie 23 133 16 16 0
CIRBP_ENST00000586472 CIRBP Q14011 Cold-inducible RNA-binding protein chr19 Not Cancer Driver No 1 hippie 19 129 13 13 0
CKS1B CKS1B P61024 Cyclin-dependent kinases regulatory subunit 1 chr1 Not Cancer Driver No 1 hippie 10 10 0 0 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie, biogrid 20 19 0 0 4
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 hippie 151 65 9 9 0
DBF4 DBF4 Q9UBU7 Protein DBF4 homolog A chr7 Not Cancer Driver No 1 hippie 75 333 26 26 0
DIMT1 DIMT1 Q9UNQ2 Probable dimethyladenosine transferase chr5 Not Cancer Driver No 1 hippie 28 37 2 2 0
DOT1L DOT1L Q8TEK3 Histone-lysine N-methyltransferase, H3 lysine-79 specific chr19 Compendium Yes 1 intact, hippie 178 988 118 118 0
ELOB_ENST00000409906 ELOB Q15370 Elongin-B chr16 Not Cancer Driver No 1 intact, hippie 13 69 10 10 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EXOSC2 EXOSC2 Q13868 Exosome complex component RRP4 chr9 Not Cancer Driver No 1 intact, hippie 21 47 6 6 2
FTL FTL P02792 Ferritin light chain chr19 Not Cancer Driver No 1 hippie, biogrid 19 36 7 7 2
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 hippie 115 854 96 96 0
HARS2_ENST00000642231 HARS2 P49590 Histidine--tRNA ligase, mitochondrial chr5 Not Cancer Driver No 1 hippie 48 34 4 4 2
HAUS1 HAUS1 Q96CS2 HAUS augmin-like complex subunit 1 chr18 Not Cancer Driver No 1 hippie 47 60 11 11 0
HMGA1 HMGA1 P17096 High mobility group protein HMG-I/HMG-Y chr6 Census Yes 1 hippie 6 107 6 6 0
HNRNPM HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 hippie 108 463 67 67 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 Census Yes 1 hippie 97 327 47 47 0
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 intact, hippie 58 350 44 44 0
LRWD1 LRWD1 Q9UFC0 Leucine-rich repeat and WD repeat-containing protein 1 chr7 Not Cancer Driver No 1 intact, hippie 75 133 17 17 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 2 intact, hippie 104 275 38 38 1
MCM4 MCM4 P33991 DNA replication licensing factor MCM4 chr8 Not Cancer Driver No 1 hippie 121 215 35 35 0
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 intact, hippie 88 109 20 20 1
MCM6 MCM6 Q14566 DNA replication licensing factor MCM6 chr2 Not Cancer Driver No 1 hippie 101 122 13 13 0
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 Not Cancer Driver No 1 hippie 101 128 22 22 0
MGMT MGMT B4DEE8 Methylated-DNA--protein-cysteine methyltransferase chr10 Census Yes 1 hippie 43 40 15 15 0
MRM3 MRM3 Q9HC36 rRNA methyltransferase 3, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 45 83 8 8 0
MRPL11 MRPL11 Q9Y3B7 39S ribosomal protein L11, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 25 12 1 1 0
MRPS15 MRPS15 P82914 28S ribosomal protein S15, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 35 72 7 7 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NFIL3 NFIL3 Q16649 Nuclear factor interleukin-3-regulated protein chr9 Not Cancer Driver No 1 hippie 57 333 41 41 0
ORC1_ENST00000371566 ORC1 Q13415 Origin recognition complex subunit 1 chr1 Not Cancer Driver No 1 hippie 100 338 46 46 5
ORC2 ORC2 Q13416 Origin recognition complex subunit 2 chr2 Not Cancer Driver No 10 intact, hippie 67 248 22 22 0
ORC3_ENST00000392844 ORC3 Q9UBD5 Origin recognition complex subunit 3 chr6 Not Cancer Driver No 8 intact, hippie 70 63 5 5 0
ORC4_ENST00000392857 ORC4 O43929 Origin recognition complex subunit 4 chr2 Not Cancer Driver No 9 intact, hippie 52 14 2 2 1
ORC5 ORC5 O43913 Origin recognition complex subunit 5 chr7 Not Cancer Driver No 8 intact, hippie 43 16 2 2 0
ORC6 ORC6 Q9Y5N6 Origin recognition complex subunit 6 chr16 Not Cancer Driver No 1 hippie 23 69 10 10 1
PHF3 PHF3 Q92576 PHD finger protein 3 chr6 Not Cancer Driver No 1 intact, hippie 260 1718 217 217 0
PHF6_ENST00000370803 PHF6 Q8IWS0 PHD finger protein 6 chrX Census, Compendium Yes 1 hippie 52 172 19 19 6
PHIP PHIP Q8WWQ0 PH-interacting protein chr6 Not Cancer Driver No 1 hippie 239 835 110 110 0
POLE3 POLE3 Q9NRF9 DNA polymerase epsilon subunit 3 chr9 Not Cancer Driver No 1 hippie 11 117 9 9 0
PSME3_ENST00000590720 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 1 hippie 20 25 5 5 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 Census, Compendium Yes 1 hippie 140 282 32 32 22
RBM10_ENST00000377604 RBM10 P98175 RNA-binding protein 10 chrX Census, Compendium Yes 1 hippie 112 777 99 99 0
RFC3 RFC3 P40938 Replication factor C subunit 3 chr13 Not Cancer Driver No 1 intact, hippie 31 13 1 1 0
RFWD3 RFWD3 Q6PCD5 E3 ubiquitin-protein ligase RFWD3 chr16 Census Yes 1 hippie 68 318 30 30 1
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 28 114 16 16 0
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 Not Cancer Driver No 1 intact 27 33 2 2 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 Not Cancer Driver No 1 intact 22 48 4 4 0
SCAMP3 SCAMP3 O14828 Secretory carrier-associated membrane protein 3 chr1 Not Cancer Driver No 1 intact, hippie 46 130 23 23 0
SKP1_ENST00000517625 SKP1 P63208 S-phase kinase-associated protein 1 chr5 Not Cancer Driver No 1 hippie 19 95 17 17 0
SKP2 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 Not Cancer Driver No 1 hippie 52 52 6 6 0
SRP72_ENST00000642900 SRP72 O76094 Signal recognition particle subunit SRP72 chr4 Not Cancer Driver No 1 intact, hippie 79 237 22 22 1
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 1 hippie 33 361 20 20 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 1 hippie 28 310 16 16 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 1 hippie, biogrid 48 229 28 28 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRIM26 TRIM26 Q12899 Tripartite motif-containing protein 26 chr6 Not Cancer Driver No 1 intact, hippie 67 153 16 16 0
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 Not Cancer Driver No 1 intact, hippie 46 159 23 23 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 Not Cancer Driver No 1 intact, hippie 20 102 8 8 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 Not Cancer Driver No 1 hippie 87 118 11 11 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 66 140 12 12 0
ZNF174_ENST00000571936 ZNF174 Q15697 Zinc finger protein 174 chr16 Not Cancer Driver No 1 intact, hippie 51 274 38 38 0
ZNF768 ZNF768 Q9H5H4 Zinc finger protein 768 chr16 Not Cancer Driver No 1 intact, hippie 95 340 62 62 0