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NUP133 ,NUP133 ,Q8WUM0
  • Uniprot Accession= Q8WUM0
  • Ensembl Transcript= ENST00000261396.5
  • Uniprot Name= NUP133
  • Name= Nuclear pore complex protein Nup133
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 36
  • Number of Interaction partner in biogrid: 49
  • Number of Interaction partner in hippie: 128
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAAS AAAS Q9NRG9 Aladin chr12 Not Cancer Driver No 1 intact, hippie 58 116 12 12 3
ACTR1A ACTR1A P61163 Alpha-centractin chr10 Not Cancer Driver No 1 hippie 47 14 0 0 0
AHCTF1 AHCTF1 Q8WYP5 Protein ELYS chr1 Not Cancer Driver No 2 hippie, biogrid 296 1060 130 130 0
B9D2 B9D2 Q9BPU9 B9 domain-containing protein 2 chr19 Not Cancer Driver No 1 intact, hippie 36 4 4 4 1
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
C19orf53 C19orf53 Q9UNZ5 Leydig cell tumor 10 kDa protein homolog chr19 Not Cancer Driver No 1 hippie, biogrid 19 99 19 19 0
CACNA1C CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 Not Cancer Driver No 1 intact, hippie 455 744 146 146 14
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact, hippie 65 334 38 38 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 Not Cancer Driver No 1 intact 41 36 2 2 0
CD70_ENST00000245903 CD70 P32970 CD70 antigen chr19 Not Cancer Driver No 1 hippie, biogrid 33 11 2 2 0
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 Census, Compendium Yes 1 intact, hippie 52 52 5 5 3
CENPF CENPF P49454 Centromere protein F chr1 Not Cancer Driver No 1 intact, hippie 387 2136 260 260 0
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie, biogrid 73 409 55 55 0
COMTD1 COMTD1 Q86VU5 Catechol O-methyltransferase domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 11 23 0 0 0
COQ8A COQ8A Q8NI60 Atypical kinase COQ8A, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 95 166 29 29 12
COX8A COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CPSF7_ENST00000394888 CPSF7 Q8N684 Cleavage and polyadenylation specificity factor subunit 7 chr11 Not Cancer Driver No 1 hippie, biogrid 55 398 52 52 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 hippie, biogrid 84 510 73 73 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 Not Cancer Driver No 1 biogrid 126 50 8 8 4
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 Not Cancer Driver No 1 hippie, biogrid 82 91 15 15 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX Census, Compendium Yes 1 hippie, biogrid 133 301 47 47 18
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 28 11 1 1 0
DNAJC1 DNAJC1 Q96KC8 DnaJ homolog subfamily C member 1 chr10 Not Cancer Driver No 1 hippie, biogrid 60 315 44 44 0
DUSP2 DUSP2 Q05923 Dual specificity protein phosphatase 2 chr2 Not Cancer Driver No 1 hippie 24 23 3 3 0
DUSP26 DUSP26 Q9BV47 Dual specificity protein phosphatase 26 chr8 Not Cancer Driver No 1 hippie 56 14 6 6 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 hippie, biogrid 505 495 62 62 21
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 77 294 39 39 0
EED_ENST00000263360 EED O75530 Polycomb protein EED chr11 Census Yes 1 hippie 64 79 11 11 6
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 42 160 28 28 4
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FCGRT_ENST00000426395 FCGRT P55899 IgG receptor FcRn large subunit p51 chr19 Not Cancer Driver No 1 hippie, biogrid 54 65 12 12 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 71 160 25 25 0
FLNC FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 1 hippie, biogrid 546 1442 288 288 7
FOXI2 FOXI2 Q6ZQN5 Forkhead box protein I2 chr10 Not Cancer Driver No 1 intact, hippie 32 165 22 22 0
FOXL1 FOXL1 Q12952 Forkhead box protein L1 chr16 Not Cancer Driver No 1 intact, hippie 62 212 26 26 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX Not Cancer Driver No 1 hippie 38 186 16 16 10
FOXQ1 FOXQ1 Q9C009 Forkhead box protein Q1 chr6 Not Cancer Driver No 1 intact, hippie 22 245 4 4 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 intact 85 352 65 65 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie 216 669 76 76 0
GLE1 GLE1 Q53GS7 mRNA export factor GLE1 chr9 Not Cancer Driver No 1 hippie 64 299 29 29 3
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 Not Cancer Driver No 1 hippie, biogrid 55 180 8 8 0
HDAC11 HDAC11 Q96DB2 Histone deacetylase 11 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 57 18 8 8 0
HIST1H1E H1-4 P10412 Histone H1.4 chr6 Not Cancer Driver No 1 intact 66 213 63 63 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 67 283 26 26 2
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie 155 419 90 90 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KPNB1 KPNB1 Q14974 Importin subunit beta-1 chr17 Not Cancer Driver No 1 hippie 92 94 11 11 0
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 intact, hippie 114 404 58 58 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 54 65 16 16 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 3 intact, hippie, biogrid 68 544 49 49 131
LMNB1 LMNB1 P20700 Lamin-B1 chr5 Not Cancer Driver No 1 hippie, biogrid 60 404 42 42 4
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 3 intact, hippie 519 90 17 17 23
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 287 749 159 159 3
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 Census, Compendium Yes 1 hippie 41 334 39 39 7
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX Census, Compendium Yes 1 hippie, biogrid 101 349 64 64 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUP107 NUP107 P57740 Nuclear pore complex protein Nup107 chr12 Not Cancer Driver No 10 intact, hippie, biogrid 127 183 26 26 5
NUP153_ENST00000262077 NUP153 P49790 Nuclear pore complex protein Nup153 chr6 Not Cancer Driver No 1 hippie 180 1152 147 147 0
NUP155 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie, biogrid 154 221 19 19 1
NUP160 NUP160 Q12769 Nuclear pore complex protein Nup160 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 138 48 1 1 0
NUP37_ENST00000251074 NUP37 Q8NFH4 Nucleoporin Nup37 chr12 Not Cancer Driver No 3 hippie, biogrid 39 0 0 0 0
NUP43 NUP43 Q8NFH3 Nucleoporin Nup43 chr6 Not Cancer Driver No 5 intact, hippie, biogrid 47 103 9 9 0
NUP50 NUP50 Q9UKX7 Nuclear pore complex protein Nup50 chr22 Not Cancer Driver No 2 hippie, biogrid 58 333 40 40 0
NUP54 NUP54 Q7Z3B4 Nucleoporin p54 chr4 Not Cancer Driver No 1 hippie 42 233 25 25 0
NUP85 NUP85 Q9BW27 Nuclear pore complex protein Nup85 chr17 Not Cancer Driver No 7 intact, hippie, biogrid 68 32 4 4 2
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 Census Yes 3 intact, hippie, biogrid 227 1008 107 107 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 intact, hippie 100 163 32 32 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 50 10 5 5 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
POLE4 POLE4 Q9NR33 DNA polymerase epsilon subunit 4 chr2 Not Cancer Driver No 1 hippie, biogrid 4 45 1 1 0
POM121_ENST00000434423 POM121 Q96HA1 Nuclear envelope pore membrane protein POM 121 chr7 Not Cancer Driver No 1 hippie 160 1072 130 130 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PSAP PSAP P07602 Prosaposin chr10 Not Cancer Driver No 1 hippie, biogrid 59 28 2 2 8
PTPMT1 PTPMT1 Q8WUK0 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 chr11 Not Cancer Driver No 1 intact, hippie 16 0 0 0 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie, biogrid 49 140 25 25 0
PUS1 PUS1 Q9Y606 Pseudouridylate synthase 1 homolog chr12 Not Cancer Driver No 1 hippie, biogrid 48 157 18 18 1
RAE1_ENST00000371242 RAE1 P78406 mRNA export factor RAE1 chr20 Not Cancer Driver No 1 hippie 64 73 11 11 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 2 intact, hippie 89 169 38 38 22
RANBP2 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 Census, Compendium Yes 1 hippie 427 1387 177 177 3
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie 33 23 0 0 0
RHOT2 RHOT2 Q8IXI1 Mitochondrial Rho GTPase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 52 79 5 5 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 hippie 119 232 34 34 3
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 2 intact, hippie 177 586 94 94 8
RPL26L1 RPL26L1 Q9UNX3 60S ribosomal protein L26-like 1 chr5 Not Cancer Driver No 1 hippie 21 107 11 11 0
RPS6KL1_ENST00000557413 RPS6KL1 Q9Y6S9 Ribosomal protein S6 kinase-like 1 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 60 161 16 16 0
SEC13_ENST00000350697 SEC13 P55735 Protein SEC13 homolog chr3 Not Cancer Driver No 5 intact, hippie, biogrid 34 36 6 6 0
SEC61B SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 2 hippie, biogrid 11 60 7 7 0
SEC62 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 41 211 23 23 0
SEH1L_ENST00000262124 SEH1L Q96EE3 Nucleoporin SEH1 chr18 Not Cancer Driver No 2 hippie, biogrid 40 71 11 11 0
SENP2 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 Not Cancer Driver No 1 hippie 73 285 38 38 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SKA3 SKA3 Q8IX90 Spindle and kinetochore-associated protein 3 chr13 Not Cancer Driver No 1 hippie 56 230 32 32 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 177 34 8 8 0
SPAST SPAST Q9UBP0 Spastin chr2 Not Cancer Driver No 2 intact, hippie, biogrid 73 270 25 25 77
SPC24 SPC24 Q8NBT2 Kinetochore protein Spc24 chr19 Not Cancer Driver No 1 intact 9 88 5 5 0
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 hippie, biogrid 70 387 45 45 13
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 20 20 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 83 483 46 46 3
SYNE3 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 143 236 42 42 0
TCAP TCAP O15273 Telethonin chr17 Not Cancer Driver No 1 hippie 16 94 10 10 3
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 2 hippie, biogrid 78 412 52 52 0
TNFSF13B TNFSF13B Q9Y275 Tumor necrosis factor ligand superfamily member 13B chr13 Not Cancer Driver No 1 hippie 41 91 15 15 0
TOMM20 TOMM20 Q15388 Mitochondrial import receptor subunit TOM20 homolog chr1 Not Cancer Driver No 1 hippie 8 25 1 1 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TPTE2 TPTE2 Q6XPS3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 210 33 13 13 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
UBA1 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX Not Cancer Driver No 1 intact 117 165 22 22 6
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX Compendium Yes 1 hippie 35 67 13 13 2
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 1 intact, hippie 57 127 5 5 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 intact, hippie 84 316 57 57 1
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VPS33A VPS33A Q96AX1 Vacuolar protein sorting-associated protein 33A chr12 Not Cancer Driver No 1 hippie 73 46 8 8 1
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
ZMYM2_ENST00000382871 ZMYM2 Q9UBW7 Zinc finger MYM-type protein 2 chr13 Census Yes 1 hippie, biogrid 144 583 68 68 0
ZRANB1 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 Not Cancer Driver No 1 hippie 87 158 25 25 0