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NUDC ,NUDC ,Q9Y266
  • Number of Interaction partner in intact: 102
  • Number of Interaction partner in biogrid: 82
  • Number of Interaction partner in hippie: 240
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAAS AAAS Q9NRG9 Aladin chr12 Not Cancer Driver No 1 intact, hippie 58 116 12 12 3
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 Not Cancer Driver No 1 hippie 49 256 34 34 1
ACTR1A ACTR1A P61163 Alpha-centractin chr10 Not Cancer Driver No 1 hippie, biogrid 47 14 0 0 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 51 6 2 2 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 Not Cancer Driver No 1 hippie, biogrid 86 129 13 13 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 88 166 22 22 11
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 Not Cancer Driver No 1 intact, hippie 173 788 103 103 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 intact, hippie 18 5 0 0 0
ARMC8_ENST00000469044 ARMC8 Q8IUR7 Armadillo repeat-containing protein 8 chr3 Not Cancer Driver No 1 hippie 71 7 0 0 0
ASCC3 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 Not Cancer Driver No 1 biogrid 279 87 8 8 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 40 25 6 6 1
ATN1_ENST00000396684 ATN1 P54259 Atrophin-1 chr12 Not Cancer Driver No 1 intact 141 1176 139 139 6
ATP6AP1 ATP6AP1 Q15904 V-type proton ATPase subunit S1 chrX Not Cancer Driver No 1 biogrid 67 0 0 0 4
ATP6V1G1 ATP6V1G1 O75348 V-type proton ATPase subunit G 1 chr9 Not Cancer Driver No 1 biogrid 12 91 8 8 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 intact, hippie 17 112 9 9 0
BBS1 BBS1 Q8NFJ9 Bardet-Biedl syndrome 1 protein chr11 Not Cancer Driver No 1 intact, hippie 69 99 14 14 12
BBS7 BBS7 Q8IWZ6 Bardet-Biedl syndrome 7 protein chr4 Not Cancer Driver No 1 intact, hippie 99 56 8 8 4
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BOD1L1 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 Not Cancer Driver No 1 biogrid 387 3023 384 384 0
BOP1 BOP1 Q14137 Ribosome biogenesis protein BOP1 chr8 Not Cancer Driver No 1 hippie 20 304 19 19 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 3 intact, hippie, biogrid 80 45 4 4 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 Not Cancer Driver No 1 intact, hippie 162 29 9 9 0
CAMLG CAMLG P49069 Guided entry of tail-anchored proteins factor CAMLG chr5 Not Cancer Driver No 1 biogrid 32 157 16 16 0
CAST_ENST00000395813 CAST P20810 Calpastatin chr5 Not Cancer Driver No 1 hippie, biogrid 73 708 73 73 0
CCDC6 CCDC6 Q16204 Coiled-coil domain-containing protein 6 chr10 Census, Compendium Yes 1 hippie, biogrid 59 373 52 52 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CDCA8_ENST00000327331 CDCA8 Q53HL2 Borealin chr1 Not Cancer Driver No 1 biogrid 23 170 13 13 0
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CFAP52 CFAP52 Q8N1V2 Cilia- and flagella-associated protein 52 chr17 Not Cancer Driver No 1 intact, hippie 107 4 0 0 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 287 145 18 18 151
CHAF1B CHAF1B Q13112 Chromatin assembly factor 1 subunit B chr21 Not Cancer Driver No 1 hippie 65 186 30 30 0
CHMP2A_ENST00000601220 CHMP2A O43633 Charged multivesicular body protein 2a chr19 Not Cancer Driver No 1 biogrid 29 161 22 22 0
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 Not Cancer Driver No 1 biogrid 198 634 64 64 0
CMAS CMAS Q8NFW8 N-acylneuraminate cytidylyltransferase chr12 Not Cancer Driver No 1 biogrid 49 89 8 8 0
COG3 COG3 Q96JB2 Conserved oligomeric Golgi complex subunit 3 chr13 Not Cancer Driver No 1 biogrid 72 109 7 7 0
COPS4_ENST00000264389 COPS4 Q9BT78 COP9 signalosome complex subunit 4 chr4 Not Cancer Driver No 1 biogrid 50 13 0 0 0
CORO1B CORO1B Q9BR76 Coronin-1B chr11 Not Cancer Driver No 1 hippie 41 138 10 10 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 hippie 61 84 13 13 0
CORO2B CORO2B Q9UQ03 Coronin-2B chr15 Not Cancer Driver No 1 hippie 85 37 7 7 0
CPSF1 CPSF1 Q10570 Cleavage and polyadenylation specificity factor subunit 1 chr8 Not Cancer Driver No 1 hippie 177 298 42 42 0
CRYAA CRYAA P02489 Alpha-crystallin A chain chr21 Not Cancer Driver No 1 intact, hippie 34 42 11 11 10
CSTB CSTB P04080 Cystatin-B chr21 Not Cancer Driver No 1 hippie, biogrid 7 40 0 0 1
CTCFL_ENST00000371196 CTCFL Q8NI51 Transcriptional repressor CTCFL chr20 Not Cancer Driver No 1 hippie 136 266 61 61 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
DCAF11 DCAF11 Q8TEB1 DDB1- and CUL4-associated factor 11 chr14 Not Cancer Driver No 1 intact, hippie 89 149 25 25 0
DCAF4 DCAF4 Q8WV16 DDB1- and CUL4-associated factor 4 chr14 Not Cancer Driver No 1 intact, hippie 59 114 11 11 0
DCAF4L2 DCAF4L2 Q8NA75 DDB1- and CUL4-associated factor 4-like protein 2 chr8 Not Cancer Driver No 1 intact, hippie 251 25 12 12 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
DGKE DGKE P52429 Diacylglycerol kinase epsilon chr17 Not Cancer Driver No 1 intact, hippie, biogrid 84 34 3 3 2
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 67 17 0 0 10
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 Not Cancer Driver No 1 intact 116 232 55 55 0
DMWD DMWD Q09019 Dystrophia myotonica WD repeat-containing protein chr19 Not Cancer Driver No 1 hippie 66 374 24 24 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 intact, hippie 37 153 16 16 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 50 174 27 27 0
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 4 intact, hippie, biogrid 35 196 26 26 0
DNAJB4 DNAJB4 Q9UDY4 DnaJ homolog subfamily B member 4 chr1 Not Cancer Driver No 2 intact, hippie 41 160 20 20 0
DYNC1I1 DYNC1I1 O14576 Cytoplasmic dynein 1 intermediate chain 1 chr7 Not Cancer Driver No 1 hippie 146 255 60 60 0
DYNC1I2_ENST00000409773 DYNC1I2 Q13409 Cytoplasmic dynein 1 intermediate chain 2 chr2 Not Cancer Driver No 1 hippie, biogrid 82 300 42 42 1
DYNC1LI1 DYNC1LI1 Q9Y6G9 Cytoplasmic dynein 1 light intermediate chain 1 chr3 Not Cancer Driver No 1 hippie 46 208 20 20 0
DYNLRB1 DYNLRB1 Q9NP97 Dynein light chain roadblock-type 1 chr20 Not Cancer Driver No 1 hippie 23 19 4 4 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EIF1B EIF1B O60739 Eukaryotic translation initiation factor 1b chr3 Not Cancer Driver No 1 hippie 12 6 0 0 0
EIF2B5 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 Not Cancer Driver No 1 biogrid 76 179 16 16 29
EIF3C EIF3C Q99613 Eukaryotic translation initiation factor 3 subunit C chr16 Not Cancer Driver No 1 biogrid 15 391 12 12 0
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 Not Cancer Driver No 1 intact, hippie 30 17 3 3 0
EIPR1_ENST00000382125 EIPR1 Q53HC9 EARP and GARP complex-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 52 71 4 4 0
ELF3_ENST00000367283 ELF3 P78545 ETS-related transcription factor Elf-3 chr1 Census, Compendium Yes 1 intact, hippie 94 145 34 34 0
EMC2 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 biogrid 48 29 3 3 0
EML1_ENST00000262233 EML1 O00423 Echinoderm microtubule-associated protein-like 1 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 146 205 31 31 2
EML4 EML4 Q9HC35 Echinoderm microtubule-associated protein-like 4 chr2 Census, Compendium Yes 1 hippie 105 385 41 41 0
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie 51 21 2 2 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
ERH ERH P84090 Enhancer of rudimentary homolog chr14 Not Cancer Driver No 1 biogrid 7 11 0 0 0
ETF1 ETF1 P62495 Eukaryotic peptide chain release factor subunit 1 chr5 Not Cancer Driver No 1 hippie 60 28 11 11 0
EVC2 EVC2 Q86UK5 Limbin chr4 Not Cancer Driver No 1 intact, hippie 240 335 71 71 2
EXOSC4 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 Not Cancer Driver No 1 biogrid 34 23 0 0 0
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 Not Cancer Driver No 1 biogrid 58 154 18 18 1
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 83 241 34 34 0
FAM120C FAM120C Q9NX05 Constitutive coactivator of PPAR-gamma-like protein 2 chrX Not Cancer Driver No 1 hippie 162 508 77 77 0
FBXL7 FBXL7 Q9UJT9 F-box/LRR-repeat protein 7 chr5 Not Cancer Driver No 1 intact, hippie 199 117 33 33 0
FBXO24_ENST00000241071 FBXO24 O75426 F-box only protein 24 chr7 Not Cancer Driver No 1 intact, hippie 119 55 10 10 0
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 75 20 3 3 7
FBXW2 FBXW2 Q9UKT8 F-box/WD repeat-containing protein 2 chr9 Not Cancer Driver No 1 intact, hippie 49 0 0 0 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie, biogrid 322 230 38 38 0
FKBP5 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 1 intact, hippie 70 150 20 20 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie, biogrid 39 24 3 3 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie 216 669 76 76 0
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 Not Cancer Driver No 1 hippie 47 138 17 17 0
GNB2 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 1 intact 50 21 0 0 7
GNB4_ENST00000468623 GNB4 Q9HAV0 Guanine nucleotide-binding protein subunit beta-4 chr3 Not Cancer Driver No 1 intact, hippie 49 27 3 3 2
GNB5 GNB5 O14775 Guanine nucleotide-binding protein subunit beta-5 chr15 Not Cancer Driver No 1 hippie 60 16 1 1 1
GOLT1B GOLT1B Q9Y3E0 Vesicle transport protein GOT1B chr12 Not Cancer Driver No 1 biogrid 26 0 0 0 0
GRK6_ENST00000355472 GRK6 P43250 G protein-coupled receptor kinase 6 chr5 Not Cancer Driver No 1 hippie, biogrid 65 68 10 10 0
GTF2E1 GTF2E1 P29083 General transcription factor IIE subunit 1 chr3 Not Cancer Driver No 1 biogrid 71 264 48 48 0
GTF2H1_ENST00000453096 GTF2H1 P32780 General transcription factor IIH subunit 1 chr11 Not Cancer Driver No 1 hippie 52 139 11 11 0
GTF3C5_ENST00000372097 GTF3C5 Q9Y5Q8 General transcription factor 3C polypeptide 5 chr9 Not Cancer Driver No 1 intact 75 157 21 21 0
HCFC2 HCFC2 Q9Y5Z7 Host cell factor 2 chr12 Not Cancer Driver No 1 hippie 95 279 34 34 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 118 718 73 73 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 hippie 35 203 29 29 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 Compendium Yes 1 hippie 78 169 34 34 0
HLA-C HLA-C P10321 HLA class I histocompatibility antigen, C alpha chain chr6 Not Cancer Driver No 1 hippie 104 175 58 58 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 intact, hippie 106 257 37 37 0
HUS1 HUS1 O60921 Checkpoint protein HUS1 chr7 Not Cancer Driver No 1 biogrid 25 17 2 2 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
IFT122_ENST00000348417 IFT122 Q9HBG6 Intraflagellar transport protein 122 homolog chr3 Not Cancer Driver No 1 hippie 157 54 5 5 5
IFT140 IFT140 Q96RY7 Intraflagellar transport protein 140 homolog chr16 Not Cancer Driver No 1 intact, hippie 176 161 27 27 10
IFT172 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 Not Cancer Driver No 2 intact, hippie 219 96 10 10 8
IFT80 IFT80 Q9P2H3 Intraflagellar transport protein 80 homolog chr3 Not Cancer Driver No 2 intact, hippie 117 21 2 2 2
IGBP1_ENST00000356413 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 51 193 28 28 0
INS INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 15 5 1 1 22
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KATNB1 KATNB1 Q9BVA0 Katanin p80 WD40 repeat-containing subunit B1 chr16 Not Cancer Driver No 1 intact, hippie 70 179 24 24 3
KDM6B_ENST00000448097 KDM6B O15054 Lysine-specific demethylase 6B chr17 Not Cancer Driver No 1 hippie 189 1278 142 142 2
KIAA0556 KATNIP O60303 Katanin-interacting protein chr16 Not Cancer Driver No 1 intact 240 982 137 137 0
KIF21B KIF21B O75037 Kinesin-like protein KIF21B chr1 Not Cancer Driver No 1 intact, hippie 308 775 159 159 0
KLF16 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 intact, hippie 13 204 8 8 0
KLHDC1 KLHDC1 Q8N7A1 Kelch domain-containing protein 1 chr14 Not Cancer Driver No 1 intact, hippie 36 37 7 7 0
KLHDC8A KLHDC8A Q8IYD2 Kelch domain-containing protein 8A chr1 Not Cancer Driver No 1 intact, hippie 60 3 4 4 0
KLHL26 KLHL26 Q53HC5 Kelch-like protein 26 chr19 Not Cancer Driver No 1 intact, hippie 75 56 5 5 0
KLHL34 KLHL34 Q8N239 Kelch-like protein 34 chrX Not Cancer Driver No 1 intact, hippie 103 77 12 12 0
KLHL38 KLHL38 Q2WGJ6 Kelch-like protein 38 chr8 Not Cancer Driver No 1 intact, hippie 114 3 2 2 0
KLHL6 KLHL6 Q8WZ60 Kelch-like protein 6 chr3 Compendium Yes 1 intact, hippie 149 25 7 7 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 intact, hippie 58 350 44 44 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie, biogrid 86 94 13 13 1
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 biogrid 74 611 69 69 0
LLGL1 LLGL1 Q15334 Lethal(2) giant larvae protein homolog 1 chr17 Not Cancer Driver No 1 hippie 101 265 12 12 0
LLGL2 LLGL2 Q6P1M3 LLGL scribble cell polarity complex component 2 chr17 Not Cancer Driver No 1 hippie 120 266 26 26 0
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie, biogrid 63 222 25 25 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LRWD1 LRWD1 Q9UFC0 Leucine-rich repeat and WD repeat-containing protein 1 chr7 Not Cancer Driver No 1 intact, hippie 75 133 17 17 0
LXN LXN Q9BS40 Latexin chr3 Not Cancer Driver No 1 hippie 21 91 9 9 0
MAD1L1_ENST00000399654 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 Not Cancer Driver No 1 hippie, biogrid 117 526 77 77 0
MAEL MAEL Q96JY0 Protein maelstrom homolog chr1 Not Cancer Driver No 1 intact, hippie 126 114 35 35 0
MAGEL2 MAGEL2 Q9UJ55 MAGE-like protein 2 chr15 Not Cancer Driver No 1 hippie 178 1010 118 118 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 74 355 44 44 0
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 Not Cancer Driver No 1 hippie, biogrid 116 276 41 41 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 Not Cancer Driver No 1 intact, hippie 51 50 15 15 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX Not Cancer Driver No 1 biogrid 63 16 4 4 9
MDH2 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 39 8 1 1 3
MFN2_ENST00000444836 MFN2 O95140 Mitofusin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 80 81 9 9 20
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 113 740 56 56 0
MKS1 MKS1 Q9NXB0 Meckel syndrome type 1 protein chr17 Not Cancer Driver No 1 intact, hippie 82 152 23 23 2
MLST8_ENST00000397124 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 Not Cancer Driver No 1 intact, hippie 37 45 3 3 0
MOS MOS P00540 Proto-oncogene serine/threonine-protein kinase mos chr8 Not Cancer Driver No 1 intact, hippie 94 16 4 4 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 45 11 0 0 0
MTMR7 MTMR7 Q9Y216 Myotubularin-related protein 7 chr8 Not Cancer Driver No 1 hippie 98 160 26 26 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NAGK_ENST00000244204 NAGK Q9UJ70 N-acetyl-D-glucosamine kinase chr2 Not Cancer Driver No 1 hippie 46 5 1 1 0
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 Not Cancer Driver No 1 intact, hippie 109 142 18 18 0
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 biogrid 88 89 8 8 0
NEK8 NEK8 Q86SG6 Serine/threonine-protein kinase Nek8 chr17 Not Cancer Driver No 1 intact, hippie 102 167 40 40 3
NFATC2 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 Census, Compendium Yes 1 hippie, biogrid 194 722 162 162 0
NHLRC1 NHLRC1 Q6VVB1 E3 ubiquitin-protein ligase NHLRC1 chr6 Not Cancer Driver No 1 intact, hippie 66 18 3 3 22
NHLRC2 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 74 103 12 12 0
NPHP4 NPHP4 O75161 Nephrocystin-4 chr1 Not Cancer Driver No 1 intact, hippie 176 469 54 54 17
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUBP2 NUBP2 Q9Y5Y2 Cytosolic Fe-S cluster assembly factor NUBP2 chr16 Not Cancer Driver No 1 hippie, biogrid 38 14 0 0 0
NUDCD1 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 75 38 4 4 0
NUP43 NUP43 Q8NFH3 Nucleoporin Nup43 chr6 Not Cancer Driver No 1 biogrid 47 103 9 9 0
NUP85 NUP85 Q9BW27 Nuclear pore complex protein Nup85 chr17 Not Cancer Driver No 1 hippie 68 32 4 4 2
NWD1_ENST00000552788 NWD1 Q149M9 NACHT domain- and WD repeat-containing protein 1 chr19 Not Cancer Driver No 1 intact, hippie 323 87 15 15 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OFD1 OFD1 O75665 Oral-facial-digital syndrome 1 protein chrX Not Cancer Driver No 1 hippie 129 476 58 58 5
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 Not Cancer Driver No 1 biogrid 114 131 17 17 60
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
OTUD4_ENST00000447906 OTUD4 Q01804 OTU domain-containing protein 4 chr4 Not Cancer Driver No 1 hippie 148 788 120 120 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 50 10 5 5 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 Not Cancer Driver No 2 hippie, biogrid 42 82 11 11 7
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 Compendium Yes 1 hippie 89 242 49 49 0
PAPOLA PAPOLA P51003 Poly(A) polymerase alpha chr14 Not Cancer Driver No 1 hippie 97 293 28 28 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PEX7 PEX7 O00628 Peroxisomal targeting signal 2 receptor chr6 Not Cancer Driver No 1 intact, hippie 32 0 0 0 2
PGD PGD P52209 6-phosphogluconate dehydrogenase, decarboxylating chr1 Not Cancer Driver No 1 biogrid 73 19 3 3 0
PHLPP1 PHLPP1 O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 chr18 Not Cancer Driver No 1 intact, hippie 134 744 29 29 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIWIL1 PIWIL1 Q96J94 Piwi-like protein 1 chr12 Not Cancer Driver No 1 intact, hippie 202 172 37 37 0
PIWIL4 PIWIL4 Q7Z3Z4 Piwi-like protein 4 chr11 Not Cancer Driver No 1 intact, hippie 115 89 11 11 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 152 919 121 121 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
POC1A POC1A Q8NBT0 POC1 centriolar protein homolog A chr3 Not Cancer Driver No 3 hippie, biogrid 51 88 8 8 1
POC1B POC1B Q8TC44 POC1 centriolar protein homolog B chr12 Not Cancer Driver No 4 intact, hippie, biogrid 52 86 8 8 1
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 Census, Compendium Yes 1 hippie 179 214 31 31 2
POLR2K POLR2K P53803 DNA-directed RNA polymerases I, II, and III subunit RPABC4 chr8 Not Cancer Driver No 1 biogrid 10 11 1 1 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 Census, Compendium Yes 1 hippie 113 31 6 6 9
PPME1_ENST00000328257 PPME1 Q9Y570 Protein phosphatase methylesterase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 35 146 9 9 0
PPP5C PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 Not Cancer Driver No 1 hippie 70 73 12 12 0
PPP6C_ENST00000373547 PPP6C O00743 Serine/threonine-protein phosphatase 6 catalytic subunit chr9 Census, Compendium Yes 1 hippie 63 0 0 0 0
PPP6R2_ENST00000216061 PPP6R2 O75170 Serine/threonine-protein phosphatase 6 regulatory subunit 2 chr22 Not Cancer Driver No 1 hippie, biogrid 103 491 63 63 0
PRDM1 PRDM1 O75626 PR domain zinc finger protein 1 chr6 Census, Compendium Yes 1 intact 145 337 66 66 0
PREB PREB Q9HCU5 Prolactin regulatory element-binding protein chr2 Not Cancer Driver No 1 hippie 56 91 10 10 0
PRKAB1 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 Not Cancer Driver No 1 intact, hippie 39 124 13 13 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 1 intact, hippie 71 109 16 16 0
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie, biogrid 255 225 26 26 8
PSMB6 PSMB6 P28072 Proteasome subunit beta type-6 chr17 Not Cancer Driver No 1 biogrid 19 22 1 1 0
PUF60 PUF60 Q9UHX1 Poly(U)-binding-splicing factor PUF60 chr8 Not Cancer Driver No 1 hippie 56 214 14 14 1
RABGGTA RABGGTA Q92696 Geranylgeranyl transferase type-2 subunit alpha chr14 Not Cancer Driver No 1 intact 74 37 2 2 0
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 Not Cancer Driver No 1 intact, hippie 204 208 43 43 36
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact, hippie 137 417 61 61 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 19 54 4 4 0
RPGR_ENST00000339363 RPGR Q92834 X-linked retinitis pigmentosa GTPase regulator chrX Not Cancer Driver No 1 intact, hippie 115 639 64 64 25
RPS6KB2 RPS6KB2 Q9UBS0 Ribosomal protein S6 kinase beta-2 chr11 Not Cancer Driver No 1 hippie 54 194 16 16 0
RRP9 RRP9 O43818 U3 small nucleolar RNA-interacting protein 2 chr3 Not Cancer Driver No 1 hippie, biogrid 53 146 9 9 0
SCAP SCAP Q12770 Sterol regulatory element-binding protein cleavage-activating protein chr3 Not Cancer Driver No 1 intact, hippie 145 329 36 36 0
SCYL1 SCYL1 Q96KG9 N-terminal kinase-like protein chr11 Not Cancer Driver No 1 biogrid 85 312 32 32 0
SIM2 SIM2 Q14190 Single-minded homolog 2 chr21 Not Cancer Driver No 1 intact, hippie 62 262 12 12 0
SLC35A1 SLC35A1 P78382 CMP-sialic acid transporter chr6 Not Cancer Driver No 1 biogrid 23 0 0 0 0
SLC39A9 SLC39A9 Q9NUM3 Zinc transporter ZIP9 chr14 Not Cancer Driver No 1 biogrid 34 44 4 4 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 62 488 56 56 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie, biogrid 16 93 9 9 79
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 83 483 46 46 3
SYMPK SYMPK Q92797 Symplekin chr19 Not Cancer Driver No 1 hippie 156 398 42 42 0
TBL1Y TBL1Y Q9BQ87 F-box-like/WD repeat-containing protein TBL1Y chrY Not Cancer Driver No 1 intact, hippie 31 138 8 8 0
TBL3 TBL3 Q12788 Transducin beta-like protein 3 chr16 Not Cancer Driver No 1 hippie 82 48 8 8 0
TFDP3 TFDP3 Q5H9I0 Transcription factor Dp family member 3 chrX Not Cancer Driver No 1 intact, hippie 84 186 42 42 0
THOC6 THOC6 Q86W42 THO complex subunit 6 homolog chr16 Not Cancer Driver No 1 intact, hippie 49 16 4 4 1
TIMM9_ENST00000555593 TIMM9 Q9Y5J7 Mitochondrial import inner membrane translocase subunit Tim9 chr14 Not Cancer Driver No 1 hippie, biogrid 9 8 1 1 0
TIMP2 TIMP2 P16035 Metalloproteinase inhibitor 2 chr17 Not Cancer Driver No 1 intact, hippie 31 6 2 2 0
TINF2 TINF2 Q9BSI4 TERF1-interacting nuclear factor 2 chr14 Not Cancer Driver No 1 hippie 38 190 17 17 4
TLE2_ENST00000262953 TLE2 Q04725 Transducin-like enhancer protein 2 chr19 Not Cancer Driver No 1 hippie 78 283 29 29 0
TLE6 TLE6 Q9H808 Transducin-like enhancer protein 6 chr19 Not Cancer Driver No 1 intact, hippie 89 227 31 31 1
TLN1 TLN1 Q9Y490 Talin-1 chr9 Not Cancer Driver No 1 hippie 278 1109 126 126 0
TNFRSF10D TNFRSF10D Q9UBN6 Tumor necrosis factor receptor superfamily member 10D chr8 Not Cancer Driver No 1 hippie 51 193 28 28 0
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 intact, hippie 254 781 156 156 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 hippie 227 1632 190 190 0
TRIM17_ENST00000366698 TRIM17 Q9Y577 E3 ubiquitin-protein ligase TRIM17 chr1 Not Cancer Driver No 1 hippie 64 127 19 19 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 Census, Compendium Yes 1 intact, hippie, biogrid 120 537 61 61 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRMT1_ENST00000357720 TRMT1 Q9NXH9 tRNA (guanine(26)-N(2))-dimethyltransferase chr19 Not Cancer Driver No 1 hippie, biogrid 82 200 24 24 0
TSSK1B TSSK1B Q9BXA7 Testis-specific serine/threonine-protein kinase 1 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 104 114 36 36 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 hippie, biogrid 59 52 11 11 8
TUBA4A TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 1 hippie, biogrid 73 39 4 4 5
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie, biogrid 40 63 11 11 5
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UGP2 UGP2 Q16851 UTP--glucose-1-phosphate uridylyltransferase chr2 Not Cancer Driver No 1 hippie 65 55 7 7 1
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 intact, hippie 38 36 4 4 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 intact, hippie 142 117 36 36 133
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VPS26A_ENST00000263559 VPS26A O75436 Vacuolar protein sorting-associated protein 26A chr10 Not Cancer Driver No 1 hippie 27 44 2 2 0
VPS29_ENST00000549578 VPS29 Q9UBQ0 Vacuolar protein sorting-associated protein 29 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 Not Cancer Driver No 1 hippie 68 99 9 9 1
WDFY2 WDFY2 Q96P53 WD repeat and FYVE domain-containing protein 2 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 49 20 2 2 0
WDR31 WDR31 Q8NA23 WD repeat-containing protein 31 chr9 Not Cancer Driver No 1 intact, hippie 52 5 1 1 0
WDR35 WDR35 Q9P2L0 WD repeat-containing protein 35 chr2 Not Cancer Driver No 2 intact, hippie 137 42 3 3 6
WDR36 WDR36 Q8NI36 WD repeat-containing protein 36 chr5 Not Cancer Driver No 1 intact, hippie 140 89 11 11 2
WDR60 DYNC2I1 Q8WVS4 Cytoplasmic dynein 2 intermediate chain 1 chr7 Not Cancer Driver No 3 intact 131 520 63 63 1
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 Not Cancer Driver No 1 biogrid 25 7 1 1 0
WDR7 WDR7 Q9Y4E6 WD repeat-containing protein 7 chr18 Not Cancer Driver No 1 biogrid 199 292 37 37 0
WDR81 WDR81 Q562E7 WD repeat-containing protein 81 chr17 Not Cancer Driver No 1 intact, hippie 164 721 51 51 1
WDR88 WDR88 Q6ZMY6 WD repeat-containing protein 88 chr19 Not Cancer Driver No 1 hippie 85 73 10 10 0
WDR90 WDR90 Q96KV7 WD repeat-containing protein 90 chr16 Not Cancer Driver No 1 intact, hippie 193 251 31 31 0
WDR91 WDR91 A4D1P6 WD repeat-containing protein 91 chr7 Not Cancer Driver No 1 intact, hippie 99 206 38 38 0
WDTC1 WDTC1 Q8N5D0 WD and tetratricopeptide repeats protein 1 chr1 Not Cancer Driver No 1 intact, hippie 81 154 21 21 0
WIPI2 WIPI2 Q9Y4P8 WD repeat domain phosphoinositide-interacting protein 2 chr7 Not Cancer Driver No 1 hippie 64 68 5 5 1
WRAP73 WRAP73 Q9P2S5 WD repeat-containing protein WRAP73 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 50 5 0 0 0
WSB2_ENST00000315436 WSB2 Q9NYS7 WD repeat and SOCS box-containing protein 2 chr12 Not Cancer Driver No 1 hippie 48 37 7 7 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 Not Cancer Driver No 1 biogrid 129 427 63 63 0
YAF2_ENST00000534854 YAF2 Q8IY57 YY1-associated factor 2 chr12 Not Cancer Driver No 1 hippie 27 166 27 27 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
YTHDC1_ENST00000344157 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 biogrid 137 597 117 117 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZYX ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie 83 385 52 52 0