ADSL |
ADSL |
P30566 |
Adenylosuccinate lyase |
chr22 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
68 |
36 |
9 |
9 |
27 |
AK4 |
AK4 |
P27144 |
Adenylate kinase 4, mitochondrial |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
26 |
24 |
3 |
3 |
0 |
AMY1A |
AMY1A |
P0DUB6 |
Alpha-amylase 1A |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie |
20 |
29 |
0 |
0 |
0 |
AMY1C |
AMY1C |
P0DTE8 |
Alpha-amylase 1C |
chr1 |
Not Cancer Driver |
No
|
1 |
biogrid |
37 |
29 |
2 |
2 |
0 |
ARHGAP1 |
ARHGAP1 |
Q07960 |
Rho GTPase-activating protein 1 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
39 |
90 |
8 |
8 |
0 |
ARL8A |
ARL8A |
Q96BM9 |
ADP-ribosylation factor-like protein 8A |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
23 |
0 |
0 |
0 |
0 |
ATL3 |
ATL3 |
Q6DD88 |
Atlastin-3 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
43 |
57 |
5 |
5 |
1 |
BAIAP2L1 |
BAIAP2L1 |
Q9UHR4 |
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
76 |
293 |
42 |
42 |
0 |
BCAP31_ENST00000345046 |
BCAP31 |
P51572 |
B-cell receptor-associated protein 31 |
chrX |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
37 |
104 |
14 |
14 |
0 |
BPIFA1_ENST00000375413 |
BPIFA1 |
Q9NP55 |
BPI fold-containing family A member 1 |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
54 |
0 |
0 |
0 |
0 |
BTF3L4 |
BTF3L4 |
Q96K17 |
Transcription factor BTF3 homolog 4 |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
11 |
131 |
8 |
8 |
0 |
CDK2 |
CDK2 |
P24941 |
Cyclin-dependent kinase 2 |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
24 |
0 |
0 |
0 |
0 |
CKAP5 |
CKAP5 |
Q14008 |
Cytoskeleton-associated protein 5 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
198 |
634 |
64 |
64 |
0 |
CLPP |
CLPP |
Q16740 |
ATP-dependent Clp protease proteolytic subunit, mitochondrial |
chr19 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
22 |
83 |
9 |
9 |
3 |
COQ9 |
COQ9 |
O75208 |
Ubiquinone biosynthesis protein COQ9, mitochondrial |
chr16 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
43 |
111 |
13 |
13 |
0 |
DIS3 |
DIS3 |
Q9Y2L1 |
Exosome complex exonuclease RRP44 |
chr13 |
Compendium |
Yes
|
1 |
hippie, biogrid |
121 |
235 |
32 |
32 |
0 |
DNM1L_ENST00000549701 |
DNM1L |
O00429 |
Dynamin-1-like protein |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
67 |
212 |
23 |
23 |
7 |
DUSP3 |
DUSP3 |
P51452 |
Dual specificity protein phosphatase 3 |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
21 |
4 |
1 |
1 |
0 |
ECPAS_ENST00000338205 |
ECPAS |
Q5VYK3 |
Proteasome adapter and scaffold protein ECM29 |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie |
176 |
240 |
22 |
22 |
0 |
EHD1_ENST00000359393 |
EHD1 |
Q9H4M9 |
EH domain-containing protein 1 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
72 |
90 |
12 |
12 |
0 |
EHD4 |
EHD4 |
Q9H223 |
EH domain-containing protein 4 |
chr15 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
54 |
98 |
7 |
7 |
0 |
ELAC2 |
ELAC2 |
Q9BQ52 |
Zinc phosphodiesterase ELAC protein 2 |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
86 |
208 |
30 |
30 |
10 |
EPS8L2_ENST00000530636 |
EPS8L2 |
Q9H6S3 |
Epidermal growth factor receptor kinase substrate 8-like protein 2 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
68 |
372 |
31 |
31 |
0 |
F11R |
F11R |
Q9Y624 |
Junctional adhesion molecule A |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
47 |
72 |
15 |
15 |
0 |
FAM162A |
FAM162A |
Q96A26 |
Protein FAM162A |
chr3 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
18 |
53 |
8 |
8 |
0 |
GAS6 |
GAS6 |
Q14393 |
Growth arrest-specific protein 6 |
chr13 |
Not Cancer Driver |
No
|
1 |
intact, hippie, biogrid |
82 |
42 |
6 |
6 |
0 |
GNL1 |
GNL1 |
P36915 |
Guanine nucleotide-binding protein-like 1 |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
62 |
268 |
24 |
24 |
0 |
GNPNAT1 |
GNPNAT1 |
Q96EK6 |
Glucosamine 6-phosphate N-acetyltransferase |
chr14 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
19 |
24 |
5 |
5 |
0 |
GSTK1_ENST00000358406 |
GSTK1 |
Q9Y2Q3 |
Glutathione S-transferase kappa 1 |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
33 |
30 |
3 |
3 |
0 |
HDHD5 |
HDHD5 |
Q9BXW7 |
Haloacid dehalogenase-like hydrolase domain-containing 5 |
chr22 |
Not Cancer Driver |
No
|
1 |
hippie |
47 |
49 |
6 |
6 |
0 |
HDLBP_ENST00000391976 |
HDLBP |
Q00341 |
Vigilin |
chr2 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
195 |
555 |
87 |
87 |
0 |
HGS |
HGS |
O14964 |
Hepatocyte growth factor-regulated tyrosine kinase substrate |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
109 |
528 |
74 |
74 |
0 |
HSPA6 |
HSPA6 |
P17066 |
Heat shock 70 kDa protein 6 |
chr1 |
Not Cancer Driver |
No
|
1 |
intact, hippie, biogrid |
112 |
235 |
27 |
27 |
0 |
IST1_ENST00000541571 |
IST1 |
P53990 |
IST1 homolog |
chr16 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
31 |
185 |
17 |
17 |
0 |
KITLG |
KITLG |
P21583 |
Kit ligand |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
48 |
61 |
9 |
9 |
1 |
KLC2_ENST00000394067 |
KLC2 |
Q9H0B6 |
Kinesin light chain 2 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
75 |
344 |
49 |
49 |
0 |
LETM1 |
LETM1 |
O95202 |
Mitochondrial proton/calcium exchanger protein |
chr4 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
77 |
286 |
28 |
28 |
0 |
LIPF_ENST00000238983 |
LIPF |
P07098 |
Gastric triacylglycerol lipase |
chr10 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
74 |
0 |
0 |
0 |
0 |
LRRC4 |
LRRC4 |
Q9HBW1 |
Leucine-rich repeat-containing protein 4 |
chr7 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
117 |
110 |
14 |
14 |
0 |
LRRC4C |
LRRC4C |
Q9HCJ2 |
Leucine-rich repeat-containing protein 4C |
chr11 |
Not Cancer Driver |
No
|
2 |
intact, hippie |
271 |
152 |
54 |
54 |
0 |
MANF |
MANF |
P55145 |
Mesencephalic astrocyte-derived neurotrophic factor |
chr3 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
14 |
1 |
0 |
0 |
0 |
MAP2K1 |
MAP2K1 |
Q02750 |
Dual specificity mitogen-activated protein kinase kinase 1 |
chr15 |
Census, Compendium |
Yes
|
1 |
hippie, biogrid |
94 |
96 |
24 |
24 |
6 |
MAP2K2 |
MAP2K2 |
P36507 |
Dual specificity mitogen-activated protein kinase kinase 2 |
chr19 |
Census |
Yes
|
1 |
hippie, biogrid |
58 |
105 |
14 |
14 |
4 |
MCTS1_ENST00000371317 |
MCTS1 |
Q9ULC4 |
Malignant T-cell-amplified sequence 1 |
chrX |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
34 |
0 |
0 |
0 |
0 |
MUC5B |
MUC5B |
Q9HC84 |
Mucin-5B |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
911 |
3134 |
586 |
586 |
0 |
NAA10 |
NAA10 |
P41227 |
N-alpha-acetyltransferase 10 |
chrX |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
33 |
117 |
17 |
17 |
3 |
NAA50 |
NAA50 |
Q9GZZ1 |
N-alpha-acetyltransferase 50 |
chr3 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
14 |
14 |
1 |
1 |
0 |
NAE1_ENST00000290810 |
NAE1 |
Q13564 |
NEDD8-activating enzyme E1 regulatory subunit |
chr16 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
39 |
69 |
3 |
3 |
0 |
NCEH1_ENST00000543711 |
NCEH1 |
Q6PIU2-3 |
Isoform 3 of Neutral cholesterol ester hydrolase 1 |
chr3 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
38 |
0 |
0 |
0 |
0 |
NDRG1 |
NDRG1 |
Q92597 |
Protein NDRG1 |
chr8 |
Census |
Yes
|
1 |
hippie, biogrid |
66 |
140 |
22 |
22 |
0 |
NDUFA12 |
NDUFA12 |
Q9UI09 |
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
18 |
31 |
6 |
6 |
0 |
NMD3_ENST00000351193 |
NMD3 |
Q96D46 |
60S ribosomal export protein NMD3 |
chr3 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
67 |
104 |
20 |
20 |
0 |
NOMO1 |
NOMO1 |
Q15155 |
Nodal modulator 1 |
chr16 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
130 |
128 |
23 |
23 |
0 |
NT5C2_ENST00000404739 |
NT5C2 |
P49902 |
Cytosolic purine 5'-nucleotidase |
chr10 |
Census |
Yes
|
1 |
hippie, biogrid |
57 |
85 |
8 |
8 |
0 |
NUDT16L1 |
NUDT16L1 |
Q9BRJ7 |
Tudor-interacting repair regulator protein |
chr16 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
16 |
6 |
0 |
0 |
0 |
OXSR1 |
OXSR1 |
O95747 |
Serine/threonine-protein kinase OSR1 |
chr3 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
69 |
208 |
29 |
29 |
0 |
PBK_ENST00000301905 |
PBK |
Q96KB5 |
Lymphokine-activated killer T-cell-originated protein kinase |
chr8 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
23 |
92 |
6 |
6 |
0 |
PGA4 |
PGA4 |
P0DJD7 |
Pepsin A-4 |
chr11 |
Not Cancer Driver |
No
|
1 |
biogrid |
0 |
24 |
0 |
0 |
0 |
PGA5 |
PGA5 |
P0DJD9 |
Pepsin A-5 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie |
25 |
24 |
2 |
2 |
0 |
PICALM |
PICALM |
Q13492 |
Phosphatidylinositol-binding clathrin assembly protein |
chr11 |
Census |
Yes
|
1 |
hippie, biogrid |
89 |
320 |
42 |
42 |
0 |
POR |
POR |
P16435 |
NADPH--cytochrome P450 reductase |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
62 |
93 |
4 |
4 |
9 |
PPME1_ENST00000328257 |
PPME1 |
Q9Y570 |
Protein phosphatase methylesterase 1 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
35 |
146 |
9 |
9 |
0 |
PPP2R5D |
PPP2R5D |
Q14738 |
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
64 |
178 |
13 |
13 |
4 |
PPP4R1 |
PPP4R1 |
Q8TF05 |
Serine/threonine-protein phosphatase 4 regulatory subunit 1 |
chr18 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
92 |
304 |
20 |
20 |
0 |
PRIM1 |
PRIM1 |
P49642 |
DNA primase small subunit |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
31 |
22 |
1 |
1 |
0 |
PRPSAP2 |
PRPSAP2 |
O60256 |
Phosphoribosyl pyrophosphate synthase-associated protein 2 |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
54 |
19 |
3 |
3 |
0 |
PSMF1_ENST00000333082 |
PSMF1 |
Q92530 |
Proteasome inhibitor PI31 subunit |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
45 |
140 |
26 |
26 |
0 |
PTPN1 |
PTPN1 |
P18031 |
Tyrosine-protein phosphatase non-receptor type 1 |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
49 |
140 |
25 |
25 |
0 |
RAP1B_ENST00000393436 |
RAP1B |
P61224 |
Ras-related protein Rap-1b |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
26 |
14 |
3 |
3 |
0 |
RECQL_ENST00000421138 |
RECQL |
P46063 |
ATP-dependent DNA helicase Q1 |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
67 |
91 |
5 |
5 |
0 |
RGPD1 |
RGPD1 |
P0DJD0 |
RANBP2-like and GRIP domain-containing protein 1 |
chr2 |
Not Cancer Driver |
No
|
1 |
hippie |
31 |
634 |
10 |
10 |
0 |
RGPD2 |
RGPD2 |
P0DJD1 |
RANBP2-like and GRIP domain-containing protein 2 |
chr2 |
Not Cancer Driver |
No
|
1 |
biogrid |
50 |
633 |
13 |
13 |
0 |
RHOA |
RHOA |
P61586 |
Transforming protein RhoA |
chr3 |
Census, Compendium |
Yes
|
1 |
hippie, biogrid |
99 |
46 |
13 |
13 |
2 |
RMDN1 |
RMDN1 |
Q96DB5 |
Regulator of microtubule dynamics protein 1 |
chr8 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
25 |
17 |
0 |
0 |
0 |
RPN1 |
RPN1 |
P04843 |
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 |
chr3 |
Census |
Yes
|
1 |
intact, hippie |
50 |
69 |
3 |
3 |
0 |
RPUSD2 |
RPUSD2 |
Q8IZ73 |
Pseudouridylate synthase RPUSD2 |
chr15 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
49 |
231 |
22 |
22 |
0 |
SBDS |
SBDS |
Q9Y3A5 |
Ribosome maturation protein SBDS |
chr7 |
Census |
Yes
|
1 |
hippie, biogrid |
28 |
12 |
1 |
1 |
2 |
SH3GL1 |
SH3GL1 |
Q99961 |
Endophilin-A2 |
chr19 |
Census |
Yes
|
1 |
hippie, biogrid |
45 |
245 |
33 |
33 |
0 |
SNX12 |
SNX12 |
Q9UMY4 |
Sorting nexin-12 |
chrX |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
22 |
28 |
4 |
4 |
0 |
SNX1_ENST00000559844 |
SNX1 |
Q13596 |
Sorting nexin-1 |
chr15 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
61 |
214 |
25 |
25 |
0 |
SNX2 |
SNX2 |
O60749 |
Sorting nexin-2 |
chr5 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
45 |
218 |
18 |
18 |
0 |
SNX3 |
SNX3 |
O60493 |
Sorting nexin-3 |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
21 |
37 |
4 |
4 |
0 |
SNX5_ENST00000377759 |
SNX5 |
Q9Y5X3 |
Sorting nexin-5 |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
33 |
91 |
13 |
13 |
0 |
SNX6 |
SNX6 |
Q9UNH7 |
Sorting nexin-6 |
chr14 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
33 |
85 |
7 |
7 |
0 |
STK26 |
STK26 |
Q9P289 |
Serine/threonine-protein kinase 26 |
chrX |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
62 |
119 |
18 |
18 |
0 |
TIGAR |
TIGAR |
Q9NQ88 |
Fructose-2,6-bisphosphatase TIGAR |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie |
44 |
39 |
9 |
9 |
0 |
TKFC |
TKFC |
Q3LXA3 |
Triokinase/FMN cyclase |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie |
66 |
91 |
14 |
14 |
2 |
TLN1 |
TLN1 |
Q9Y490 |
Talin-1 |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
278 |
1109 |
126 |
126 |
0 |
TOMM22 |
TOMM22 |
Q9NS69 |
Mitochondrial import receptor subunit TOM22 homolog |
chr22 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
18 |
83 |
9 |
9 |
0 |
TOMM34 |
TOMM34 |
Q15785 |
Mitochondrial import receptor subunit TOM34 |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
32 |
113 |
15 |
15 |
0 |
TPP2_ENST00000376065 |
TPP2 |
P29144 |
Tripeptidyl-peptidase 2 |
chr13 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
147 |
218 |
40 |
40 |
1 |
TRMT6 |
TRMT6 |
Q9UJA5 |
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
42 |
208 |
17 |
17 |
0 |
TRNT1 |
TRNT1 |
Q96Q11 |
CCA tRNA nucleotidyltransferase 1, mitochondrial |
chr3 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
60 |
49 |
8 |
8 |
7 |
TSFM_ENST00000454289 |
TSFM |
P43897 |
Elongation factor Ts, mitochondrial |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
37 |
74 |
7 |
7 |
2 |
TTC1 |
TTC1 |
Q99614 |
Tetratricopeptide repeat protein 1 |
chr5 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
28 |
211 |
21 |
21 |
0 |
TTLL12 |
TTLL12 |
Q14166 |
Tubulin--tyrosine ligase-like protein 12 |
chr22 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
69 |
100 |
6 |
6 |
0 |
UBA5 |
UBA5 |
Q9GZZ9 |
Ubiquitin-like modifier-activating enzyme 5 |
chr3 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
41 |
126 |
8 |
8 |
7 |
UBA6 |
UBA6 |
A0AVT1 |
Ubiquitin-like modifier-activating enzyme 6 |
chr4 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
133 |
90 |
10 |
10 |
0 |
UBLCP1 |
UBLCP1 |
Q8WVY7 |
Ubiquitin-like domain-containing CTD phosphatase 1 |
chr5 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
39 |
42 |
4 |
4 |
0 |
USO1_ENST00000514213 |
USO1 |
O60763 |
General vesicular transport factor p115 |
chr4 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
78 |
368 |
28 |
28 |
0 |
VAMP2_ENST00000316509 |
VAMP2 |
P63027 |
Vesicle-associated membrane protein 2 |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
7 |
47 |
4 |
4 |
3 |
VPS26A_ENST00000263559 |
VPS26A |
O75436 |
Vacuolar protein sorting-associated protein 26A |
chr10 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
27 |
44 |
2 |
2 |
0 |
WASF2 |
WASF2 |
Q9Y6W5 |
Wiskott-Aldrich syndrome protein family member 2 |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
61 |
400 |
43 |
43 |
0 |
YRDC |
YRDC |
Q86U90 |
Threonylcarbamoyl-AMP synthase |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
17 |
45 |
1 |
1 |
2 |