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NPPA ,NPPA ,P01160
  • Number of Interaction partner in intact: 27
  • Number of Interaction partner in biogrid: 41
  • Number of Interaction partner in hippie: 55
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
A2ML1 A2ML1 A8K2U0 Alpha-2-macroglobulin-like protein 1 chr12 Not Cancer Driver No 2 hippie, biogrid 269 97 22 22 0
ACADVL_ENST00000356839 ACADVL P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial chr17 Not Cancer Driver No 2 intact, hippie, biogrid 50 100 5 5 37
ACPP_ENST00000336375 ACP3 P15309 Prostatic acid phosphatase chr3 Not Cancer Driver No 1 intact 81 24 5 5 0
ALOX12B ALOX12B O75342 Arachidonate 12-lipoxygenase, 12R-type chr17 Not Cancer Driver No 2 intact, hippie, biogrid 101 16 3 3 18
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 Not Cancer Driver No 2 intact, hippie, biogrid 99 62 12 12 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 41 83 12 12 9
CAPNS2 CAPNS2 Q96L46 Calpain small subunit 2 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 21 56 5 5 0
CBWD1_ENST00000356521 CBWD1 Q9BRT8 COBW domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 27 62 8 8 0
CPA4 CPA4 Q9UI42 Carboxypeptidase A4 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 76 59 12 12 0
CST6 CST6 Q15828 Cystatin-M chr11 Not Cancer Driver No 1 intact, hippie, biogrid 20 28 2 2 0
CTPS2_ENST00000380241 CTPS2 Q9NRF8 CTP synthase 2 chrX Not Cancer Driver No 1 hippie, biogrid 57 65 9 9 0
CTSV CTSV O60911 Cathepsin L2 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 55 7 1 1 0
ECM1_ENST00000369047 ECM1 Q16610 Extracellular matrix protein 1 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 91 219 28 28 1
EPB41_ENST00000373798 EPB41 P11171 Protein 4.1 chr1 Not Cancer Driver No 1 hippie 101 557 69 69 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
GDPD3 GDPD3 Q7L5L3 Lysophospholipase D GDPD3 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 50 12 2 2 0
HNF4A HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 Not Cancer Driver No 1 hippie 135 127 48 48 5
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 Not Cancer Driver No 1 intact, hippie 52 23 3 3 1
IMPA2 IMPA2 O14732 Inositol monophosphatase 2 chr18 Not Cancer Driver No 1 intact, hippie, biogrid 44 21 1 1 0
IPO4 IPO4 Q8TEX9 Importin-4 chr14 Not Cancer Driver No 1 hippie, biogrid 106 87 5 5 0
ISCA2 ISCA2 Q86U28 Iron-sulfur cluster assembly 2 homolog, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 13 38 3 3 1
IVL IVL P07476 Involucrin chr1 Not Cancer Driver No 2 intact, hippie, biogrid 115 585 115 115 0
JUP JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 2 intact, hippie, biogrid 112 241 37 37 0
LCN2_ENST00000277480 LCN2 P80188 Neutrophil gelatinase-associated lipocalin chr9 Not Cancer Driver No 2 intact, hippie, biogrid 29 4 3 3 0
MAGEA12 MAGEA12 P43365 Melanoma-associated antigen 12 chrX Not Cancer Driver No 1 hippie 128 102 43 43 0
ME1 ME1 P48163 NADP-dependent malic enzyme chr6 Not Cancer Driver No 1 intact, hippie, biogrid 109 64 10 10 0
METAP1 METAP1 P53582 Methionine aminopeptidase 1 chr4 Not Cancer Driver No 2 hippie, biogrid 37 61 3 3 0
MME_ENST00000492661 MME P08473 Neprilysin chr3 Not Cancer Driver No 1 hippie 189 40 17 17 4
NDUFAF5 NDUFAF5 Q5TEU4 Arginine-hydroxylase NDUFAF5, mitochondrial chr20 Not Cancer Driver No 2 hippie, biogrid 47 69 15 15 3
NDUFAF7 NDUFAF7 Q7L592 Protein arginine methyltransferase NDUFAF7, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 53 19 3 3 0
NME1-NME2 NME1-NME2 P22392-2 Isoform 3 of Nucleoside diphosphate kinase B chr17 Not Cancer Driver No 1 biogrid 21 20 1 1 0
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 Not Cancer Driver No 1 hippie 13 11 1 1 0
NPR1 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 Not Cancer Driver No 1 hippie 141 78 16 16 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 Not Cancer Driver No 1 hippie 144 89 18 18 20
NPR3 NPR3 P17342 Atrial natriuretic peptide receptor 3 chr5 Not Cancer Driver No 1 hippie 95 58 8 8 0
NR5A2 NR5A2 O00482 Nuclear receptor subfamily 5 group A member 2 chr1 Not Cancer Driver No 1 hippie 126 154 35 35 0
NUDT8 NUDT8 Q8WV74 Mitochondrial coenzyme A diphosphatase NUDT8 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 22 69 10 10 0
OBSCN_ENST00000422127 OBSCN Q5VST9 Obscurin chr1 Not Cancer Driver No 1 intact, hippie, biogrid 1208 2623 368 368 0
PDF PDF Q9HBH1 Peptide deformylase, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 7 8 0 0 0
PM20D1 PM20D1 Q6GTS8 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 chr1 Not Cancer Driver No 2 hippie, biogrid 79 42 10 10 0
PMPCA PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 2 intact, hippie, biogrid 67 23 3 3 4
PMPCB PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 2 hippie, biogrid 55 22 3 3 5
PMVK PMVK Q15126 Phosphomevalonate kinase chr1 Not Cancer Driver No 2 intact, hippie, biogrid 38 3 0 0 0
POF1B_ENST00000262753 POF1B Q8WVV4 Protein POF1B chrX Not Cancer Driver No 1 intact, hippie, biogrid 154 391 104 104 1
RORB_ENST00000396204 RORB Q92753 Nuclear receptor ROR-beta chr9 Not Cancer Driver No 1 hippie 107 87 22 22 1
S100A9 S100A9 P06702 Protein S100-A9 chr1 Not Cancer Driver No 1 hippie, biogrid 18 76 7 7 0
SDR9C7 SDR9C7 Q8NEX9 Short-chain dehydrogenase/reductase family 9C member 7 chr12 Not Cancer Driver No 2 hippie, biogrid 51 3 1 1 2
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 Not Cancer Driver No 2 intact, hippie, biogrid 142 47 28 28 0
SERPINB4 SERPINB4 P48594 Serpin B4 chr18 Not Cancer Driver No 2 hippie, biogrid 120 48 18 18 0
SMYD2 SMYD2 Q9NRG4 N-lysine methyltransferase SMYD2 chr1 Not Cancer Driver No 2 hippie, biogrid 42 12 0 0 0
TGM1 TGM1 P22735 Protein-glutamine gamma-glutamyltransferase K chr14 Not Cancer Driver No 2 hippie, biogrid 118 230 37 37 65
TMEM63C TMEM63C Q9P1W3 Calcium permeable stress-gated cation channel 1 chr14 Not Cancer Driver No 1 hippie, biogrid 114 84 14 14 0
TRPC4AP TRPC4AP Q8TEL6 Short transient receptor potential channel 4-associated protein chr20 Not Cancer Driver No 1 hippie, biogrid 84 70 7 7 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 64 543 58 58 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 intact, hippie 82 581 79 79 8
UBQLN4 UBQLN4 Q9NRR5 Ubiquilin-4 chr1 Not Cancer Driver No 1 intact, hippie 70 561 67 67 1
VGF VGF O15240 Neurosecretory protein VGF chr7 Not Cancer Driver No 1 hippie, biogrid 48 593 47 47 0