Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACAD9 | ACAD9 | Q9H845 | Complex I assembly factor ACAD9, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 69 | 28 | 5 | 5 | 12 |
| ACOT13 | ACOT13 | Q9NPJ3 | Acyl-coenzyme A thioesterase 13 | chr6 | Not Cancer Driver | No | 1 | hippie | 15 | 23 | 2 | 2 | 0 |
| ACSF2_ENST00000300441 | ACSF2 | Q96CM8 | Medium-chain acyl-CoA ligase ACSF2, mitochondrial | chr17 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 73 | 55 | 10 | 10 | 0 |
| ADI1 | ADI1 | Q9BV57 | Acireductone dioxygenase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 23 | 1 | 1 | 0 |
| ALDH1L1_ENST00000393434 | ALDH1L1 | O75891 | Cytosolic 10-formyltetrahydrofolate dehydrogenase | chr3 | Not Cancer Driver | No | 1 | hippie | 159 | 87 | 19 | 19 | 0 |
| ATP5F1C | ATP5F1C | P36542 | ATP synthase subunit gamma, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie | 39 | 11 | 0 | 0 | 0 |
| ATP5ME | ATP5ME | P56385 | ATP synthase subunit e, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie | 6 | 18 | 2 | 2 | 0 |
| ATP5PB | ATP5PB | P24539 | ATP synthase F(0) complex subunit B1, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 37 | 2 | 0 | 0 | 0 |
| ATP5PD | ATP5PD | O75947 | ATP synthase subunit d, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 12 | 15 | 0 | 0 | 0 |
| ATP5PF_ENST00000400090 | ATP5PF | P18859 | ATP synthase-coupling factor 6, mitochondrial | chr21 | Not Cancer Driver | No | 1 | hippie | 14 | 15 | 1 | 1 | 0 |
| ATP5PO | ATP5PO | P48047 | ATP synthase subunit O, mitochondrial | chr21 | Not Cancer Driver | No | 1 | hippie | 19 | 9 | 2 | 2 | 0 |
| ATXN1L | ATXN1L | P0C7T5 | Ataxin-1-like | chr16 | Not Cancer Driver | No | 1 | hippie | 30 | 476 | 19 | 19 | 0 |
| BCAT2 | BCAT2 | O15382 | Branched-chain-amino-acid aminotransferase, mitochondrial | chr19 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 54 | 19 | 0 | 0 | 2 |
| BCKDHA | BCKDHA | P12694 | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 53 | 121 | 18 | 18 | 11 |
| BCKDK | BCKDK | O14874 | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 62 | 39 | 3 | 3 | 3 |
| BOLA3 | BOLA3 | Q53S33 | BolA-like protein 3 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 27 | 1 | 1 | 2 |
| C17orf80_ENST00000535032 | C17orf80 | Q9BSJ5 | Uncharacterized protein C17orf80 | chr17 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 64 | 455 | 53 | 53 | 0 |
| C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 103 | 6 | 6 | 2 |
| CAMK2A_ENST00000348628 | CAMK2A | Q9UQM7 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 62 | 10 | 10 | 7 |
| CAPN1_ENST00000533129 | CAPN1 | P07384 | Calpain-1 catalytic subunit | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 32 | 2 | 2 | 1 |
| CBR3 | CBR3 | O75828 | Carbonyl reductase [NADPH] 3 | chr21 | Not Cancer Driver | No | 1 | hippie | 26 | 66 | 6 | 6 | 0 |
| CD2AP | CD2AP | Q9Y5K6 | CD2-associated protein | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 456 | 60 | 60 | 0 |
| CHCHD2 | CHCHD2 | Q9Y6H1 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 24 | 114 | 21 | 21 | 1 |
| CLPB | CLPB | Q9H078 | Caseinolytic peptidase B protein homolog | chr11 | Not Cancer Driver | No | 1 | hippie | 69 | 224 | 25 | 25 | 11 |
| CLPX | CLPX | O76031 | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial | chr15 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 66 | 195 | 22 | 22 | 1 |
| COX6A1 | COX6A1 | P12074 | Cytochrome c oxidase subunit 6A1, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 17 | 48 | 5 | 5 | 0 |
| COX6C_ENST00000522940 | COX6C | P09669 | Cytochrome c oxidase subunit 6C | chr8 | Census | Yes | 1 | hippie | 14 | 0 | 0 | 0 | 0 |
| COX7A2_ENST00000509698 | COX7A2 | D6RIE3 | Cytochrome c oxidase subunit 7A2, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie | 5 | 13 | 3 | 3 | 0 |
| CUX1_ENST00000622516 | CUX1 | Q13948 | Protein CASP | chr7 | Census, Compendium | Yes | 1 | hippie, biogrid | 114 | 347 | 64 | 64 | 0 |
| CYB5R3_ENST00000352397 | CYB5R3 | P00387 | NADH-cytochrome b5 reductase 3 | chr22 | Not Cancer Driver | No | 1 | hippie | 42 | 24 | 3 | 3 | 9 |
| CYC1 | CYC1 | P08574 | Cytochrome c1, heme protein, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie | 65 | 35 | 8 | 8 | 2 |
| ECH1 | ECH1 | Q13011 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 23 | 2 | 2 | 0 |
| ECI2 | ECI2 | O75521 | Enoyl-CoA delta isomerase 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 52 | 70 | 8 | 8 | 0 |
| ETFA | ETFA | P13804 | Electron transfer flavoprotein subunit alpha, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 34 | 2 | 2 | 3 |
| FDXR_ENST00000293195 | FDXR | P22570 | NADPH:adrenodoxin oxidoreductase, mitochondrial | chr17 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 68 | 102 | 14 | 14 | 4 |
| FECH_ENST00000262093 | FECH | P22830 | Ferrochelatase, mitochondrial | chr18 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 52 | 57 | 8 | 8 | 23 |
| FPGS | FPGS | Q05932 | Folylpolyglutamate synthase, mitochondrial | chr9 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 68 | 141 | 18 | 18 | 0 |
| GFM1_ENST00000486715 | GFM1 | Q96RP9 | Elongation factor G, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 74 | 79 | 7 | 7 | 4 |
| GLRX5 | GLRX5 | Q86SX6 | Glutaredoxin-related protein 5, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie | 7 | 23 | 0 | 0 | 2 |
| GLRX_ENST00000505427 | GLRX | P35754 | Glutaredoxin-1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 0 | 0 | 0 | 0 |
| GLS | GLS | O94925 | Glutaminase kidney isoform, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 71 | 187 | 9 | 9 | 3 |
| GTPBP8 | GTPBP8 | Q8N3Z3 | GTP-binding protein 8 | chr3 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 34 | 3 | 0 | 0 | 0 |
| HADHB | HADHB | P55084 | Trifunctional enzyme subunit beta, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 41 | 9 | 9 | 14 |
| HDAC4 | HDAC4 | P56524 | Histone deacetylase 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 182 | 749 | 132 | 132 | 0 |
| HOGA1 | HOGA1 | Q86XE5 | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 2 | 0 | 0 | 2 |
| HOXC5 | HOXC5 | Q00444 | Homeobox protein Hox-C5 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 141 | 20 | 20 | 0 |
| HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 61 | 82 | 6 | 6 | 2 |
| HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | Compendium | Yes | 1 | hippie | 44 | 127 | 9 | 9 | 2 |
| IBA57 | IBA57 | Q5T440 | Putative transferase CAF17, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 28 | 1 | 1 | 1 |
| IDE | IDE | P14735 | Insulin-degrading enzyme | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 96 | 8 | 8 | 0 |
| IFT74_ENST00000433700 | IFT74 | Q96LB3 | Intraflagellar transport protein 74 homolog | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 490 | 38 | 38 | 0 |
| IMMT | IMMT | Q16891 | MICOS complex subunit MIC60 | chr2 | Not Cancer Driver | No | 1 | hippie | 97 | 400 | 50 | 50 | 0 |
| ISOC2_ENST00000425675 | ISOC2 | Q96AB3 | Isochorismatase domain-containing protein 2 | chr19 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 24 | 8 | 0 | 0 | 0 |
| LARS2_ENST00000645846 | LARS2 | Q15031 | Leucine--tRNA ligase, mitochondrial | chr3 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 74 | 80 | 8 | 8 | 3 |
| MRM2_ENST00000440306 | MRM2 | Q9UI43 | rRNA methyltransferase 2, mitochondrial | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 37 | 15 | 1 | 1 | 1 |
| MRPL13 | MRPL13 | Q9BYD1 | 39S ribosomal protein L13, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie | 28 | 10 | 1 | 1 | 0 |
| MRPL16 | MRPL16 | Q9NX20 | 39S ribosomal protein L16, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 38 | 57 | 11 | 11 | 0 |
| MRPL22 | MRPL22 | Q9NWU5 | 39S ribosomal protein L22, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 23 | 28 | 2 | 2 | 0 |
| MRPL46 | MRPL46 | Q9H2W6 | 39S ribosomal protein L46, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie | 24 | 58 | 0 | 0 | 0 |
| MTHFS | MTHFS | P49914 | 5-formyltetrahydrofolate cyclo-ligase | chr15 | Not Cancer Driver | No | 1 | hippie | 18 | 36 | 6 | 6 | 2 |
| NARS2 | NARS2 | Q96I59 | Probable asparagine--tRNA ligase, mitochondrial | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 79 | 22 | 2 | 2 | 3 |
| NDUFA10 | NDUFA10 | O95299 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 48 | 19 | 0 | 0 | 1 |
| NDUFA11_ENST00000308961 | NDUFA11 | Q86Y39 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | chr19 | Not Cancer Driver | No | 1 | hippie | 6 | 0 | 0 | 0 | 0 |
| NDUFA12 | NDUFA12 | Q9UI09 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 31 | 6 | 6 | 0 |
| NDUFA13 | NDUFA13 | Q9P0J0 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | chr19 | Not Cancer Driver | No | 1 | hippie | 29 | 24 | 4 | 4 | 1 |
| NDUFA2 | NDUFA2 | O43678 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 10 | 0 | 0 | 0 | 0 |
| NDUFA3 | NDUFA3 | O95167 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 | chr19 | Not Cancer Driver | No | 1 | hippie | 7 | 27 | 4 | 4 | 0 |
| NDUFA5_ENST00000355749 | NDUFA5 | Q16718 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | chr7 | Not Cancer Driver | No | 1 | hippie | 10 | 10 | 1 | 1 | 0 |
| NDUFA6_ENST00000602404 | NDUFA6 | P56556 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | chr22 | Not Cancer Driver | No | 1 | hippie | 10 | 14 | 2 | 2 | 1 |
| NDUFA7 | NDUFA7 | O95182 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | chr19 | Not Cancer Driver | No | 1 | hippie | 16 | 103 | 13 | 13 | 0 |
| NDUFA8 | NDUFA8 | P51970 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | chr9 | Not Cancer Driver | No | 1 | hippie | 25 | 33 | 1 | 1 | 2 |
| NDUFA9 | NDUFA9 | Q16795 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 8 | 0 | 0 | 2 |
| NDUFAB1_ENST00000007516 | NDUFAB1 | O14561 | Acyl carrier protein, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie | 23 | 0 | 0 | 0 | 0 |
| NDUFAF1 | NDUFAF1 | Q9Y375 | Complex I intermediate-associated protein 30, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie | 44 | 63 | 8 | 8 | 4 |
| NDUFAF3 | NDUFAF3 | Q9BU61 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 | chr3 | Not Cancer Driver | No | 1 | hippie | 20 | 33 | 3 | 3 | 3 |
| NDUFAF4 | NDUFAF4 | Q9P032 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 | chr6 | Not Cancer Driver | No | 1 | hippie | 14 | 46 | 4 | 4 | 2 |
| NDUFB10 | NDUFB10 | O96000 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | chr16 | Not Cancer Driver | No | 1 | hippie | 19 | 33 | 1 | 1 | 1 |
| NDUFB11_ENST00000377811 | NDUFB11 | Q9NX14 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie | 26 | 51 | 6 | 6 | 1 |
| NDUFB1_ENST00000605997 | NDUFB1 | O75438 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 5 | 0 | 0 | 0 | 0 |
| NDUFB3 | NDUFB3 | O43676 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | chr2 | Not Cancer Driver | No | 1 | hippie | 15 | 17 | 1 | 1 | 1 |
| NDUFB4 | NDUFB4 | O95168 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | chr3 | Not Cancer Driver | No | 1 | hippie | 13 | 20 | 1 | 1 | 0 |
| NDUFB5 | NDUFB5 | O43674 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 28 | 9 | 1 | 1 | 0 |
| NDUFB7 | NDUFB7 | P17568 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | chr19 | Not Cancer Driver | No | 1 | hippie | 17 | 65 | 6 | 6 | 0 |
| NDUFB8 | NDUFB8 | O95169 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie | 28 | 64 | 11 | 11 | 3 |
| NDUFB9 | NDUFB9 | Q9Y6M9 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | chr8 | Not Cancer Driver | No | 1 | hippie | 23 | 34 | 5 | 5 | 1 |
| NDUFC2 | NDUFC2 | O95298 | NADH dehydrogenase [ubiquinone] 1 subunit C2 | chr11 | Not Cancer Driver | No | 1 | hippie | 15 | 4 | 0 | 0 | 1 |
| NDUFS1_ENST00000449699 | NDUFS1 | P28331 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 81 | 40 | 3 | 3 | 2 |
| NDUFS2 | NDUFS2 | O75306 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 58 | 49 | 5 | 5 | 4 |
| NDUFS3 | NDUFS3 | O75489 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 34 | 26 | 3 | 3 | 2 |
| NDUFS4 | NDUFS4 | O43181 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 26 | 92 | 17 | 17 | 1 |
| NDUFS5_ENST00000372967 | NDUFS5 | O43920 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | chr1 | Not Cancer Driver | No | 1 | hippie | 15 | 31 | 3 | 3 | 0 |
| NDUFS6 | NDUFS6 | O75380 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 20 | 8 | 0 | 0 | 1 |
| NDUFS7 | NDUFS7 | O75251 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 36 | 30 | 3 | 3 | 1 |
| NDUFS8 | NDUFS8 | O00217 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 27 | 37 | 2 | 2 | 3 |
| NDUFV1 | NDUFV1 | P49821 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 66 | 57 | 9 | 9 | 3 |
| NDUFV2 | NDUFV2 | P19404 | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | chr18 | Not Cancer Driver | No | 1 | hippie | 40 | 69 | 15 | 15 | 0 |
| NDUFV3_ENST00000340344 | NDUFV3 | P56181 | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | chr21 | Not Cancer Driver | No | 1 | hippie | 5 | 95 | 4 | 4 | 0 |
| NEDD8 | NEDD8 | Q15843 | NEDD8 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 36 | 5 | 5 | 0 |
| NF2 | NF2 | P35240 | Merlin | chr22 | Census, Compendium | Yes | 1 | hippie | 69 | 252 | 26 | 26 | 16 |
| NIPSNAP1 | NIPSNAP1 | Q9BPW8 | Protein NipSnap homolog 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 9 | 0 | 0 | 0 |
| NIPSNAP3A | NIPSNAP3A | Q9UFN0 | Protein NipSnap homolog 3A | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 15 | 4 | 4 | 0 |
| NIT1 | NIT1 | Q86X76 | Deaminated glutathione amidase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 18 | 3 | 3 | 0 |
| NME1_ENST00000393196 | NME1 | P15531 | Nucleoside diphosphate kinase A | chr17 | Not Cancer Driver | No | 1 | hippie | 11 | 10 | 0 | 0 | 0 |
| NME4 | NME4 | O00746 | Nucleoside diphosphate kinase, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie | 13 | 41 | 4 | 4 | 0 |
| NUDT19 | NUDT19 | A8MXV4 | Acyl-coenzyme A diphosphatase NUDT19 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 27 | 131 | 5 | 5 | 0 |
| NUDT8 | NUDT8 | Q8WV74 | Mitochondrial coenzyme A diphosphatase NUDT8 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 69 | 10 | 10 | 0 |
| NUDT9 | NUDT9 | Q9BW91 | ADP-ribose pyrophosphatase, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 177 | 16 | 16 | 0 |
| OXCT1 | OXCT1 | P55809 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 80 | 39 | 5 | 5 | 11 |
| PDAP1 | PDAP1 | Q13442 | 28 kDa heat- and acid-stable phosphoprotein | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 181 | 26 | 26 | 0 |
| PDPR | PDPR | Q8NCN5 | Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial | chr16 | Compendium | Yes | 1 | intact, hippie, biogrid | 142 | 35 | 4 | 4 | 0 |
| PITRM1_ENST00000224949 | PITRM1 | Q5JRX3 | Presequence protease, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 122 | 220 | 26 | 26 | 2 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PLPBP | PLPBP | O94903 | Pyridoxal phosphate homeostasis protein | chr8 | Not Cancer Driver | No | 1 | hippie | 30 | 96 | 12 | 12 | 3 |
| PMPCA | PMPCA | Q10713 | Mitochondrial-processing peptidase subunit alpha | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 23 | 3 | 3 | 4 |
| PMPCB | PMPCB | O75439 | Mitochondrial-processing peptidase subunit beta | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 22 | 3 | 3 | 5 |
| POLDIP2 | POLDIP2 | Q9Y2S7 | Polymerase delta-interacting protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 94 | 13 | 13 | 0 |
| POLG_ENST00000442287 | POLG | P54098 | DNA polymerase subunit gamma-1 | chr15 | Census | Yes | 2 | hippie, biogrid | 139 | 421 | 42 | 42 | 73 |
| PPM1K | PPM1K | Q8N3J5 | Protein phosphatase 1K, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie | 59 | 62 | 12 | 12 | 0 |
| PSMG4_ENST00000438998 | PSMG4 | Q5JS54 | Proteasome assembly chaperone 4 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 4 | 9 | 4 | 4 | 0 |
| PTS | PTS | Q03393 | 6-pyruvoyl tetrahydrobiopterin synthase | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 9 | 22 | 1 | 1 | 24 |
| RPUSD3 | RPUSD3 | Q6P087 | Mitochondrial mRNA pseudouridine synthase RPUSD3 | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 33 | 85 | 5 | 5 | 0 |
| RTP2 | RTP2 | Q5QGT7 | Receptor-transporting protein 2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 12 | 1 | 1 | 0 |
| SCO1 | SCO1 | O75880 | Protein SCO1 homolog, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 35 | 79 | 7 | 7 | 1 |
| SDHAF4 | SDHAF4 | Q5VUM1 | Succinate dehydrogenase assembly factor 4, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie | 14 | 76 | 10 | 10 | 0 |
| SFXN3_ENST00000393459 | SFXN3 | Q9BWM7 | Sideroflexin-3 | chr10 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
| SHARPIN | SHARPIN | Q9H0F6 | Sharpin | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 237 | 16 | 16 | 0 |
| SHMT2 | SHMT2 | P34897 | Serine hydroxymethyltransferase, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 58 | 5 | 5 | 1 |
| SIRT3 | SIRT3 | Q9NTG7 | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 33 | 60 | 2 | 2 | 0 |
| SIRT4 | SIRT4 | Q9Y6E7 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 46 | 4 | 0 | 0 | 0 |
| SLC16A1 | SLC16A1 | P53985 | Monocarboxylate transporter 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 69 | 70 | 3 | 3 | 3 |
| SLC25A20 | SLC25A20 | O43772 | Mitochondrial carnitine/acylcarnitine carrier protein | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 39 | 17 | 3 | 3 | 3 |
| SLC25A27 | SLC25A27 | O95847 | Mitochondrial uncoupling protein 4 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 20 | 2 | 2 | 0 |
| SLC31A1 | SLC31A1 | O15431 | High affinity copper uptake protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 28 | 6 | 6 | 0 |
| SOD2_ENST00000367055 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie | 32 | 25 | 5 | 5 | 0 |
| SSSCA1 | ZNRD2 | O60232 | Protein ZNRD2 | chr11 | Not Cancer Driver | No | 1 | intact | 19 | 103 | 12 | 12 | 0 |
| STOML2 | STOML2 | Q9UJZ1 | Stomatin-like protein 2, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie | 40 | 117 | 9 | 9 | 0 |
| TIMM44 | TIMM44 | O43615 | Mitochondrial import inner membrane translocase subunit TIM44 | chr19 | Not Cancer Driver | No | 1 | hippie | 56 | 175 | 22 | 22 | 0 |
| TIMMDC1 | TIMMDC1 | Q9NPL8 | Complex I assembly factor TIMMDC1, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 44 | 50 | 6 | 6 | 0 |
| TOP3A | TOP3A | Q13472 | DNA topoisomerase 3-alpha | chr17 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 103 | 293 | 31 | 31 | 2 |
| TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
| TSFM_ENST00000454289 | TSFM | P43897 | Elongation factor Ts, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 37 | 74 | 7 | 7 | 2 |
| TUBA4A | TUBA4A | P68366 | Tubulin alpha-4A chain | chr2 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 73 | 39 | 4 | 4 | 5 |
| UQCR10 | UQCR10 | Q9UDW1 | Cytochrome b-c1 complex subunit 9 | chr22 | Not Cancer Driver | No | 1 | hippie | 12 | 0 | 0 | 0 | 0 |
| UQCRB_ENST00000287022 | UQCRB | P14927 | Cytochrome b-c1 complex subunit 7 | chr8 | Not Cancer Driver | No | 1 | hippie | 28 | 2 | 1 | 1 | 0 |
| UQCRC2 | UQCRC2 | P22695 | Cytochrome b-c1 complex subunit 2, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie | 53 | 48 | 13 | 13 | 1 |
| UQCRFS1 | UQCRFS1 | P47985 | Cytochrome b-c1 complex subunit Rieske, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 43 | 47 | 4 | 4 | 1 |
| XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 140 | 12 | 12 | 0 |
| ZFYVE9 | ZFYVE9 | O95405 | Zinc finger FYVE domain-containing protein 9 | chr1 | Not Cancer Driver | No | 1 | hippie | 162 | 668 | 83 | 83 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|