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NHLH1 ,NHLH1 ,Q02575
  • Uniprot Accession= Q02575
  • Ensembl Transcript= ENST00000302101.5
  • Uniprot Name= NHLH1
  • Name= Helix-loop-helix protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 47
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 87
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ARID3A ARID3A Q99856 AT-rich interactive domain-containing protein 3A chr19 Not Cancer Driver No 1 intact, hippie 55 432 37 37 0
ARID4B ARID4B Q4LE39 AT-rich interactive domain-containing protein 4B chr1 Not Cancer Driver No 1 hippie 143 1005 118 118 0
BLM BLM P54132 Bloom syndrome protein chr15 Census Yes 1 hippie 153 667 70 70 8
BMS1 BMS1 Q14692 Ribosome biogenesis protein BMS1 homolog chr10 Not Cancer Driver No 1 intact, hippie 179 708 88 88 1
BPTF_ENST00000321892 BPTF Q12830 Nucleosome-remodeling factor subunit BPTF chr17 Not Cancer Driver No 1 hippie 309 2187 218 218 2
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
C7orf50 C7orf50 Q9BRJ6 Uncharacterized protein C7orf50 chr7 Not Cancer Driver No 1 hippie 21 126 17 17 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 intact, hippie 96 505 91 91 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 intact, hippie 59 36 6 6 0
CDCA2 CDCA2 Q69YH5 Cell division cycle-associated protein 2 chr8 Not Cancer Driver No 1 hippie 124 828 100 100 0
CENPP CENPP Q6IPU0 Centromere protein P chr9 Not Cancer Driver No 2 intact, hippie 30 40 4 4 0
CFDP1 CFDP1 Q9UEE9 Craniofacial development protein 1 chr16 Not Cancer Driver No 1 hippie 21 273 18 18 0
CLPX CLPX O76031 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie 66 195 22 22 1
CSRP3 CSRP3 P50461 Cysteine and glycine-rich protein 3 chr11 Not Cancer Driver No 1 hippie 25 31 1 1 2
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 Census, Compendium Yes 1 hippie 151 481 83 83 1
DDX24 DDX24 Q9GZR7 ATP-dependent RNA helicase DDX24 chr14 Not Cancer Driver No 1 hippie 86 452 40 40 0
DDX27 DDX27 Q96GQ7 Probable ATP-dependent RNA helicase DDX27 chr20 Not Cancer Driver No 1 hippie 101 383 50 50 0
DDX31_ENST00000372153 DDX31 Q9H8H2 Probable ATP-dependent RNA helicase DDX31 chr9 Not Cancer Driver No 1 hippie 99 342 38 38 0
DDX56 DDX56 Q9NY93 Probable ATP-dependent RNA helicase DDX56 chr7 Not Cancer Driver No 1 intact, hippie 50 107 13 13 0
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 intact, hippie 67 179 30 30 5
EBNA1BP2_ENST00000236051 EBNA1BP2 Q99848 Probable rRNA-processing protein EBP2 chr1 Not Cancer Driver No 1 hippie 38 254 34 34 0
EHMT1 EHMT1 Q9H9B1 Histone-lysine N-methyltransferase EHMT1 chr9 Not Cancer Driver No 1 hippie 182 701 97 97 1
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 Not Cancer Driver No 1 hippie 142 585 71 71 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 Not Cancer Driver No 1 hippie 397 2064 234 234 0
FOXK1 FOXK1 P85037 Forkhead box protein K1 chr7 Not Cancer Driver No 1 intact, hippie 97 511 65 65 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 Not Cancer Driver No 1 hippie 79 548 64 64 0
FTSJ3 FTSJ3 Q8IY81 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 chr17 Not Cancer Driver No 1 intact, hippie 103 533 66 66 0
GNL2 GNL2 Q13823 Nucleolar GTP-binding protein 2 chr1 Not Cancer Driver No 1 hippie 87 446 51 51 0
GPATCH4_ENST00000368232 GPATCH4 A0A0A0MRK1 G patch domain-containing protein 4 chr1 Not Cancer Driver No 1 intact, hippie 42 359 39 39 0
GTPBP4 GTPBP4 Q9BZE4 GTP-binding protein 4 chr10 Not Cancer Driver No 1 intact, hippie 79 232 34 34 0
HEXIM2_ENST00000592695 HEXIM2 Q96MH2 Protein HEXIM2 chr17 Not Cancer Driver No 1 intact, hippie 35 286 35 35 0
HIVEP1 HIVEP1 P15822 Zinc finger protein 40 chr6 Not Cancer Driver No 1 hippie 344 2238 292 292 0
IGF2BP3 IGF2BP3 O00425 Insulin-like growth factor 2 mRNA-binding protein 3 chr7 Not Cancer Driver No 1 intact, hippie 79 264 40 40 0
INO80E INO80E Q8NBZ0 INO80 complex subunit E chr16 Not Cancer Driver No 1 hippie 21 210 21 21 0
KDM6A KDM6A O15550 Lysine-specific demethylase 6A chrX Census, Compendium Yes 1 intact, hippie 173 648 71 71 0
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 Census, Compendium Yes 1 intact, hippie 446 3145 338 338 0
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 Census, Compendium Yes 1 intact, hippie 773 4386 552 552 13
KRI1 KRI1 Q8N9T8 Protein KRI1 homolog chr19 Not Cancer Driver No 1 intact, hippie 91 607 84 84 0
L3MBTL2 L3MBTL2 Q969R5 Lethal(3)malignant brain tumor-like protein 2 chr22 Not Cancer Driver No 1 intact, hippie 95 210 38 38 0
L3MBTL3_ENST00000368136 L3MBTL3 Q96JM7 Lethal(3)malignant brain tumor-like protein 3 chr6 Not Cancer Driver No 1 hippie 117 351 59 59 0
LLPH_ENST00000446587 LLPH Q9BRT6 Protein LLP homolog chr12 Not Cancer Driver No 1 intact, hippie 15 113 14 14 0
LMO1 LMO1 P25800 Rhombotin-1 chr11 Census Yes 1 hippie 23 0 0 0 0
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 Census Yes 1 hippie 35 14 1 1 0
LMO4 LMO4 P61968 LIM domain transcription factor LMO4 chr1 Not Cancer Driver No 1 hippie 30 11 1 1 0
MGA MGA Q8IWI9 MAX gene-associated protein chr15 Compendium Yes 1 intact, hippie 341 2317 259 259 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 intact, hippie 540 3169 529 529 0
NAP1L4 NAP1L4 Q99733 Nucleosome assembly protein 1-like 4 chr11 Not Cancer Driver No 1 intact, hippie 38 194 19 19 0
NFIA_ENST00000403491 NFIA Q12857 Nuclear factor 1 A-type chr1 Not Cancer Driver No 1 intact, hippie 78 347 55 55 0
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 Census Yes 1 hippie 63 254 36 36 3
NKRF_ENST00000304449 NKRF O15226 NF-kappa-B-repressing factor chrX Not Cancer Driver No 1 hippie 100 366 49 49 0
NOP16_ENST00000614830 NOP16 Q9Y3C1 Nucleolar protein 16 chr5 Not Cancer Driver No 1 intact, hippie 19 118 12 12 0
NOP2_ENST00000322166 NOP2 P46087 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase chr12 Not Cancer Driver No 1 intact, hippie 116 510 72 72 0
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 Not Cancer Driver No 1 intact, hippie 59 391 41 41 0
NOP56 NOP56 O00567 Nucleolar protein 56 chr20 Not Cancer Driver No 1 intact, hippie 83 191 34 34 0
NPM3 NPM3 O75607 Nucleoplasmin-3 chr10 Not Cancer Driver No 1 intact, hippie 23 78 11 11 0
PCGF6 PCGF6 Q9BYE7 Polycomb group RING finger protein 6 chr10 Not Cancer Driver No 1 hippie 29 142 11 11 0
PCMT1_ENST00000464889 PCMT1 A0A0A0MRJ6 Protein-L-isoaspartate O-methyltransferase chr6 Not Cancer Driver No 1 intact, hippie 34 38 4 4 0
PHF10 PHF10 Q8WUB8 PHD finger protein 10 chr6 Not Cancer Driver No 1 hippie 39 298 26 26 0
PIM1 PIM1 P11309 Serine/threonine-protein kinase pim-1 chr6 Census, Compendium Yes 1 intact, hippie 71 27 8 8 0
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 Not Cancer Driver No 1 hippie 36 94 13 13 0
PSME2 PSME2 Q9UL46 Proteasome activator complex subunit 2 chr14 Not Cancer Driver No 1 hippie 32 39 3 3 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 intact, hippie 59 328 43 43 0
RBM28 RBM28 Q9NW13 RNA-binding protein 28 chr7 Not Cancer Driver No 1 intact, hippie 97 512 66 66 1
RBM34 RBM34 P42696 RNA-binding protein 34 chr1 Not Cancer Driver No 1 intact, hippie 50 267 34 34 0
REXO4 REXO4 Q9GZR2 RNA exonuclease 4 chr9 Not Cancer Driver No 1 intact, hippie 34 298 26 26 0
RPL36AL RPL36AL Q969Q0 60S ribosomal protein L36a-like chr14 Not Cancer Driver No 1 hippie 9 64 7 7 0
RPL37A RPL37A P61513 60S ribosomal protein L37a chr2 Not Cancer Driver No 1 intact, hippie 4 0 0 0 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 intact, hippie 74 513 48 48 0
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 Not Cancer Driver No 1 hippie 273 1009 160 160 42
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie 27 0 0 0 6
SURF6 SURF6 O75683 Surfeit locus protein 6 chr9 Not Cancer Driver No 1 hippie 58 337 56 56 0
TAF6_ENST00000344095 TAF6 P49848 Transcription initiation factor TFIID subunit 6 chr7 Not Cancer Driver No 1 hippie 79 288 32 32 2
TCF12_ENST00000267811 TCF12 Q99081 Transcription factor 12 chr15 Census Yes 1 hippie 105 680 105 105 3
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 Census Yes 1 hippie 52 649 52 52 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 141 662 136 136 13
TRPS1_ENST00000220888 TRPS1 Q9UHF7 Zinc finger transcription factor Trps1 chr8 Not Cancer Driver No 1 hippie 348 800 216 216 7
UBE2O UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 Not Cancer Driver No 1 intact, hippie 129 716 68 68 0
UBN2 UBN2 Q6ZU65 Ubinuclein-2 chr7 Not Cancer Driver No 1 intact, hippie 157 1104 126 126 0
UBXN7 UBXN7 O94888 UBX domain-containing protein 7 chr3 Not Cancer Driver No 1 hippie 65 327 39 39 0
WIZ_ENST00000263381 WIZ O95785-2 Isoform 2 of Protein Wiz chr19 Not Cancer Driver No 1 intact, hippie 148 651 135 135 0
ZBTB21 ZBTB21 Q9ULJ3 Zinc finger and BTB domain-containing protein 21 chr21 Not Cancer Driver No 1 intact, hippie 136 645 75 75 0
ZBTB9 ZBTB9 Q96C00 Zinc finger and BTB domain-containing protein 9 chr6 Not Cancer Driver No 1 intact, hippie 61 256 40 40 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 Census, Compendium Yes 1 intact, hippie 246 831 200 200 8
ZNF260_ENST00000593142 ZNF260 Q3ZCT1 Zinc finger protein 260 chr19 Not Cancer Driver No 1 intact, hippie 45 91 8 8 0
ZNF512 ZNF512 Q96ME7 Zinc finger protein 512 chr2 Not Cancer Driver No 1 intact, hippie 76 280 42 42 0
ZNF644_ENST00000370440 ZNF644 Q9H582 Zinc finger protein 644 chr1 Not Cancer Driver No 1 intact, hippie 176 870 108 108 4