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NEXN ,NEXN ,Q0ZGT2
  • Number of Interaction partner in intact: 14
  • Number of Interaction partner in biogrid: 27
  • Number of Interaction partner in hippie: 80
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 hippie 70 48 14 14 84
ACTA2 ACTA2 P62736 Actin, aortic smooth muscle chr10 Not Cancer Driver No 2 hippie, biogrid 50 39 4 4 17
ACTBL2 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 Not Cancer Driver No 2 hippie, biogrid 73 29 5 5 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 3 hippie, biogrid 112 43 5 5 5
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie, biogrid 114 48 19 19 11
ACTR10 ACTR10 Q9NZ32 Actin-related protein 10 chr14 Not Cancer Driver No 2 hippie, biogrid 45 29 3 3 0
ANK3 ANK3 Q12955 Ankyrin-3 chr10 Not Cancer Driver No 2 hippie, biogrid 860 3054 579 579 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 intact, hippie 144 767 104 104 2
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
C3orf36 C3orf36 Q3SXR2 Uncharacterized protein C3orf36 chr3 Not Cancer Driver No 1 hippie, biogrid 38 133 30 30 0
C6orf201 C6orf201 Q7Z4U5 Uncharacterized protein C6orf201 chr6 Not Cancer Driver No 1 hippie, biogrid 20 128 19 19 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie 42 212 19 19 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 19 115 15 15 7
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie 37 19 0 0 0
CECR2_ENST00000342247 CECR2 Q9BXF3 Cat eye syndrome critical region protein 2 chr22 Not Cancer Driver No 1 hippie 222 1192 183 183 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CPVL_ENST00000265394 CPVL Q9H3G5 Probable serine carboxypeptidase CPVL chr7 Not Cancer Driver No 2 hippie, biogrid 81 0 0 0 0
CRYGD CRYGD P07320 Gamma-crystallin D chr2 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 6
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 42 123 9 9 1
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 hippie 151 65 9 9 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 Not Cancer Driver No 1 hippie, biogrid 193 114 11 11 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 intact, hippie 84 510 73 73 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 hippie 132 514 82 82 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EMB EMB Q6PCB8 Embigin chr5 Not Cancer Driver No 1 hippie, biogrid 78 96 18 18 0
EMCN EMCN Q9ULC0 Endomucin chr4 Not Cancer Driver No 1 hippie, biogrid 45 191 34 34 0
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 Not Cancer Driver No 1 hippie 25 141 24 24 0
FBXO34 FBXO34 Q9NWN3 F-box only protein 34 chr14 Not Cancer Driver No 1 hippie, biogrid 90 421 55 55 0
FBXO46 FBXO46 Q6PJ61 F-box only protein 46 chr19 Not Cancer Driver No 1 hippie, biogrid 72 386 59 59 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 intact, hippie 416 1456 214 214 28
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 1 intact, hippie 68 388 42 42 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GADD45GIP1 GADD45GIP1 Q8TAE8 Growth arrest and DNA damage-inducible proteins-interacting protein 1 chr19 Not Cancer Driver No 1 hippie 19 193 19 19 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
GSN GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 hippie, biogrid 76 316 28 28 2
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 Not Cancer Driver No 1 hippie 25 203 20 20 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 Not Cancer Driver No 1 hippie 38 207 38 38 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 20
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 intact, hippie 183 351 35 35 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
LARP1 LARP1 Q6PKG0-3 Isoform 2 of La-related protein 1 chr5 Not Cancer Driver No 1 hippie 136 726 100 100 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 Not Cancer Driver No 1 hippie 108 16 3 3 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 2 hippie, biogrid 88 687 81 81 0
MAB21L2 MAB21L2 Q9Y586 Protein mab-21-like 2 chr4 Not Cancer Driver No 1 intact, hippie 81 6 3 3 5
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 1 hippie 26 109 11 11 0
MTMR10 MTMR10 Q9NXD2 Myotubularin-related protein 10 chr15 Not Cancer Driver No 1 hippie, biogrid 79 98 7 7 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 310 1120 160 160 17
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 268 1237 176 176 0
MYO1B MYO1B O43795 Unconventional myosin-Ib chr2 Not Cancer Driver No 2 hippie, biogrid 144 34 4 4 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 Not Cancer Driver No 1 intact, hippie 110 66 11 11 0
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 Not Cancer Driver No 1 hippie, biogrid 126 61 6 6 0
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 204 394 43 43 0
NELL1_ENST00000357134 NELL1 Q92832 Protein kinase C-binding protein NELL1 chr11 Not Cancer Driver No 1 hippie 238 7 3 3 0
NUDCD2 NUDCD2 Q8WVJ2 NudC domain-containing protein 2 chr5 Not Cancer Driver No 1 hippie 12 39 6 6 0
NXT1 NXT1 Q9UKK6 NTF2-related export protein 1 chr20 Not Cancer Driver No 1 hippie, biogrid 16 0 0 0 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX Not Cancer Driver No 1 hippie 151 126 24 24 41
OTUB2 OTUB2 Q96DC9 Ubiquitin thioesterase OTUB2 chr14 Not Cancer Driver No 1 hippie, biogrid 30 0 0 0 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 30 22 3 3 1
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 intact, hippie 47 25 5 5 5
PPP1R9A_ENST00000433881 PPP1R9A Q9ULJ8 Neurabin-1 chr7 Not Cancer Driver No 2 hippie, biogrid 217 887 174 174 0
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 Not Cancer Driver No 1 hippie, biogrid 14 29 4 4 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 Census, Compendium Yes 1 hippie 96 281 51 51 0
SLC39A3 SLC39A3 Q9BRY0 Zinc transporter ZIP3 chr19 Not Cancer Driver No 1 hippie, biogrid 41 0 0 0 0
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 103 918 102 102 0
TES TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 56 100 7 7 0
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 Not Cancer Driver No 1 hippie 16 30 5 5 0
TMOD1_ENST00000395211 TMOD1 P28289 Tropomodulin-1 chr9 Not Cancer Driver No 1 hippie, biogrid 41 195 29 29 0
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 Not Cancer Driver No 1 hippie 69 79 11 11 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
UBA52_ENST00000595683 UBA52 P62987 Ubiquitin-60S ribosomal protein L40 chr19 Not Cancer Driver No 1 hippie, biogrid 19 45 8 8 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VMP1 VMP1 Q96GC9 Vacuole membrane protein 1 chr17 Not Cancer Driver No 1 hippie 57 68 11 11 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 Not Cancer Driver No 1 hippie 30 41 2 2 0
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 78 236 25 25 0
ZNF250 ZNF250 P15622 Zinc finger protein 250 chr8 Not Cancer Driver No 1 hippie 68 162 19 19 0
ZSCAN22 ZSCAN22 P10073 Zinc finger and SCAN domain-containing protein 22 chr19 Not Cancer Driver No 1 intact, hippie 81 250 35 35 0