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NEK7 ,NEK7 ,Q8TDX7
  • Uniprot Accession= Q8TDX7
  • Ensembl Transcript= ENST00000367385.8
  • Uniprot Name= NEK7
  • Name= Serine/threonine-protein kinase Nek7
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 121
  • Number of Interaction partner in biogrid: 118
  • Number of Interaction partner in hippie: 193
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AARS AARS1 P49588 Alanine--tRNA ligase, cytoplasmic chr16 Not Cancer Driver No 1 intact 97 140 14 14 5
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 Not Cancer Driver No 1 intact, hippie, biogrid 120 114 12 12 0
ACO2 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 Not Cancer Driver No 1 intact, hippie, biogrid 94 172 19 19 5
AHSA1 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 46 146 17 17 0
AK2 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie, biogrid 23 76 12 12 2
ALDH2 ALDH2 P05091 Aldehyde dehydrogenase, mitochondrial chr12 Census Yes 1 hippie, biogrid 60 44 1 1 0
ANKS3_ENST00000614075 ANKS3 Q6ZW76 Ankyrin repeat and SAM domain-containing protein 3 chr16 Not Cancer Driver No 4 intact, hippie, biogrid 58 292 28 28 0
ANKS6 ANKS6 Q68DC2 Ankyrin repeat and SAM domain-containing protein 6 chr9 Not Cancer Driver No 4 intact, hippie, biogrid 94 568 60 60 2
ANXA5 ANXA5 P08758 Annexin A5 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 50 33 5 5 0
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 Not Cancer Driver No 1 hippie, biogrid 138 404 59 59 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie, biogrid 34 103 14 14 0
APLNR APLNR P35414 Apelin receptor chr11 Not Cancer Driver No 1 hippie, biogrid 96 29 8 8 0
ARHGEF28_ENST00000426542 ARHGEF28 Q8N1W1 Rho guanine nucleotide exchange factor 28 chr5 Not Cancer Driver No 1 intact 188 764 88 88 0
ASNS_ENST00000394308 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 Not Cancer Driver No 1 hippie, biogrid 81 11 0 0 3
BICC1 BICC1 Q9H694 Protein bicaudal C homolog 1 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 171 645 115 115 1
C11orf65 MFI Q8NCR3 Protein MFI chr11 Not Cancer Driver No 1 intact 42 66 7 7 0
C1orf216 C1orf216 Q8TAB5 UPF0500 protein C1orf216 chr1 Not Cancer Driver No 1 intact, hippie 22 199 21 21 0
C6orf58 LEG1 Q6P5S2 Protein LEG1 homolog chr6 Not Cancer Driver No 1 intact 71 24 5 5 0
CAMTA2_ENST00000348066 CAMTA2 O94983 Calmodulin-binding transcription activator 2 chr17 Not Cancer Driver No 1 hippie 148 613 84 84 0
CAP1_ENST00000372805 CAP1 Q01518 Adenylyl cyclase-associated protein 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 70 156 31 31 0
CBS_ENST00000359624 CBS P35520 Cystathionine beta-synthase chr21 Not Cancer Driver No 2 intact, hippie 61 160 19 19 103
CNOT3 CNOT3 O75175 CCR4-NOT transcription complex subunit 3 chr19 Census, Compendium Yes 1 hippie 120 538 78 78 4
CPNE1_ENST00000352393 CPNE1 Q99829 Copine-1 chr20 Not Cancer Driver No 1 intact, hippie, biogrid 74 80 7 7 0
CPSF6_ENST00000435070 CPSF6 Q16630 Cleavage and polyadenylation specificity factor subunit 6 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 85 484 75 75 0
CRELD2_ENST00000328268 CRELD2 Q6UXH1 Protein disulfide isomerase CRELD2 chr22 Not Cancer Driver No 1 intact, hippie 39 33 6 6 0
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 Census, Compendium Yes 1 hippie, biogrid 151 481 83 83 1
CTPS1 CTPS1 P17812 CTP synthase 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 70 83 10 10 0
DCXR DCXR Q7Z4W1 L-xylulose reductase chr17 Not Cancer Driver No 1 hippie, biogrid 14 10 1 1 0
DDIT4L DDIT4L Q96D03 DNA damage-inducible transcript 4-like protein chr4 Not Cancer Driver No 1 hippie 48 5 3 3 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 82 91 15 15 0
DNAJC2 DNAJC2 Q99543 DnaJ homolog subfamily C member 2 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 67 425 48 48 0
DNASE1L1 DNASE1L1 P49184 Deoxyribonuclease-1-like 1 chrX Not Cancer Driver No 1 hippie 30 0 0 0 0
DPH3 DPH3 Q96FX2 DPH3 homolog chr3 Not Cancer Driver No 1 hippie, biogrid 12 0 0 0 0
DPYSL2_ENST00000311151 DPYSL2 Q16555 Dihydropyrimidinase-related protein 2 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 86 146 32 32 0
DRC7_ENST00000394337 DRC7 Q8IY82 Dynein regulatory complex subunit 7 chr16 Not Cancer Driver No 1 intact, hippie 164 252 51 51 0
DYNLL1_ENST00000242577 DYNLL1 P63167 Dynein light chain 1, cytoplasmic chr12 Not Cancer Driver No 3 intact, hippie, biogrid 9 0 0 0 0
EEF2 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 111 78 14 14 1
EGFL8 EGFL8 Q99944 Epidermal growth factor-like protein 8 chr6 Not Cancer Driver No 1 intact, hippie 37 56 10 10 0
EHD2 EHD2 Q9NZN4 EH domain-containing protein 2 chr19 Compendium Yes 1 hippie, biogrid 85 125 12 12 0
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 35 59 6 6 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 37 21 5 5 5
EML3_ENST00000394773 EML3 Q32P44 Echinoderm microtubule-associated protein-like 3 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 102 321 29 29 0
EML4 EML4 Q9HC35 Echinoderm microtubule-associated protein-like 4 chr2 Census, Compendium Yes 1 hippie 105 385 41 41 0
EPCAM EPCAM P16422 Epithelial cell adhesion molecule chr2 Not Cancer Driver No 1 intact, hippie 40 25 2 2 1
EVA1B EVA1B Q9NVM1 Protein eva-1 homolog B chr1 Not Cancer Driver No 1 intact, hippie 18 118 9 9 0
EZR EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie, biogrid 66 295 35 35 0
FAHD2A FAHD2A Q96GK7 Fumarylacetoacetate hydrolase domain-containing protein 2A chr2 Not Cancer Driver No 1 intact, hippie 39 8 2 2 0
FASN FASN P49327 Fatty acid synthase chr17 Not Cancer Driver No 1 intact, hippie, biogrid 291 309 42 42 0
FHL1_ENST00000345434 FHL1 Q13642 Four and a half LIM domains protein 1 chrX Not Cancer Driver No 1 intact, hippie, biogrid 56 51 7 7 13
FILIP1 FILIP1 Q7Z7B0 Filamin-A-interacting protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 256 975 220 220 0
FKBP4 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 Not Cancer Driver No 1 hippie, biogrid 46 134 12 12 0
FUT2 FUT2 Q10981 Galactoside alpha-(1,2)-fucosyltransferase 2 chr19 Not Cancer Driver No 1 hippie 54 0 0 0 0
G3BP2_ENST00000395719 G3BP2 Q9UN86 Ras GTPase-activating protein-binding protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 64 384 53 53 0
GANAB_ENST00000356638 GANAB Q14697 Neutral alpha-glucosidase AB chr11 Not Cancer Driver No 1 intact, hippie, biogrid 129 132 20 20 3
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 Not Cancer Driver No 1 intact, hippie 327 117 16 16 0
GDI2 GDI2 P50395 Rab GDP dissociation inhibitor beta chr10 Not Cancer Driver No 1 hippie, biogrid 49 23 2 2 0
GGH GGH Q92820 Gamma-glutamyl hydrolase chr8 Not Cancer Driver No 1 intact, hippie, biogrid 46 5 0 0 0
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 Not Cancer Driver No 1 hippie 74 92 21 21 5
GLG1_ENST00000422840 GLG1 Q92896 Golgi apparatus protein 1 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 134 103 7 7 0
GLO1 GLO1 Q04760 Lactoylglutathione lyase chr6 Not Cancer Driver No 1 hippie, biogrid 24 46 7 7 0
GNAO1_ENST00000638705 GNAO1 P09471 Guanine nucleotide-binding protein G(o) subunit alpha chr16 Not Cancer Driver No 1 intact, hippie 54 10 0 0 15
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 Not Cancer Driver No 1 intact, hippie, biogrid 77 73 11 11 24
GPR107_ENST00000610997 GPR107 Q5VW38 Protein GPR107 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 54 69 5 5 0
HADH_ENST00000309522 HADH Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial chr4 Not Cancer Driver No 1 intact, hippie, biogrid 33 22 5 5 3
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 46 145 14 14 0
HSD3B1 HSD3B1 P14060 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 chr1 Not Cancer Driver No 1 hippie 69 25 3 3 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 intact, hippie, biogrid 94 268 35 35 0
HSPE1 HSPE1 P61604 10 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie, biogrid 8 3 0 0 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
IDH1 IDH1 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic chr2 Census, Compendium Yes 1 hippie 553 37 3 3 0
IFT122_ENST00000348417 IFT122 Q9HBG6 Intraflagellar transport protein 122 homolog chr3 Not Cancer Driver No 1 hippie 157 54 5 5 5
IL13RA2_ENST00000243213 IL13RA2 Q14627 Interleukin-13 receptor subunit alpha-2 chrX Not Cancer Driver No 1 intact, hippie, biogrid 69 0 0 0 0
INF2 INF2 Q27J81 Inverted formin-2 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 120 635 49 49 30
ISY1_ENST00000393295 ISY1 Q9ULR0 Pre-mRNA-splicing factor ISY1 homolog chr3 Not Cancer Driver No 1 intact, hippie 29 171 18 18 0
KHSRP KHSRP Q92945 Far upstream element-binding protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 84 684 81 81 0
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 Census, Compendium Yes 1 intact, hippie, biogrid 122 586 67 67 0
KLRC1 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 Not Cancer Driver No 1 intact, hippie 49 49 10 10 0
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 67 222 38 38 0
LARP1 LARP1 Q6PKG0-3 Isoform 2 of La-related protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 136 726 100 100 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 Not Cancer Driver No 1 hippie 16 0 0 0 0
LGALS8_ENST00000366584 LGALS8 O00214 Galectin-8 chr1 Not Cancer Driver No 1 intact, hippie 43 31 6 6 0
LLGL2 LLGL2 Q6P1M3 LLGL scribble cell polarity complex component 2 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 120 266 26 26 0
LPCAT1 LPCAT1 Q8NF37 Lysophosphatidylcholine acyltransferase 1 chr5 Not Cancer Driver No 1 hippie, biogrid 85 66 11 11 0
LTV1 LTV1 Q96GA3 Protein LTV1 homolog chr6 Not Cancer Driver No 1 intact, hippie, biogrid 45 388 30 30 0
LUC7L LUC7L Q9NQ29 Putative RNA-binding protein Luc7-like 1 chr16 Not Cancer Driver No 1 hippie, biogrid 50 254 41 41 0
LUC7L2 LUC7L2 Q9Y383 Putative RNA-binding protein Luc7-like 2 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 59 262 45 45 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 Not Cancer Driver No 1 hippie 70 411 58 58 0
MCM3_ENST00000229854 MCM3 P25205 DNA replication licensing factor MCM3 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 92 310 47 47 0
MMAB MMAB Q96EY8 Corrinoid adenosyltransferase MMAB chr12 Not Cancer Driver No 1 hippie 36 68 14 14 5
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 Census Yes 1 intact, hippie, biogrid 92 37 4 4 70
MTHFD1 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 Not Cancer Driver No 1 intact, hippie, biogrid 103 129 11 11 6
MYBPHL MYBPHL A2RUH7 Myosin-binding protein H-like chr1 Not Cancer Driver No 1 intact, hippie 36 84 6 6 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYNN_ENST00000356716 MYNN Q9NPC7 Myoneurin chr3 Not Cancer Driver No 1 intact, hippie 76 214 24 24 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 61 386 44 44 0
NASP NASP P49321 Nuclear autoantigenic sperm protein chr1 Not Cancer Driver No 1 intact, hippie, biogrid 95 615 81 81 0
NCAPD2 NCAPD2 Q15021 Condensin complex subunit 1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 124 345 35 35 0
NEK6_ENST00000545174 NEK6 Q9HC98 Serine/threonine-protein kinase Nek6 chr9 Not Cancer Driver No 5 hippie, biogrid 31 36 0 0 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 Not Cancer Driver No 2 intact, hippie 35 23 0 0 0
NEK8 NEK8 Q86SG6 Serine/threonine-protein kinase Nek8 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 102 167 40 40 3
NEK9 NEK9 Q8TD19 Serine/threonine-protein kinase Nek9 chr14 Not Cancer Driver No 6 intact, hippie, biogrid 88 330 34 34 3
NFATC1 NFATC1 O95644 Nuclear factor of activated T-cells, cytoplasmic 1 chr18 Not Cancer Driver No 1 hippie, biogrid 173 713 130 130 0
NFATC2IP NFATC2IP Q8NCF5 NFATC2-interacting protein chr16 Not Cancer Driver No 1 intact, hippie 41 330 29 29 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 Not Cancer Driver No 3 intact, hippie 339 64 33 33 37
NUP188 NUP188 Q5SRE5 Nucleoporin NUP188 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 190 152 20 20 0
NUP214 NUP214 P35658 Nuclear pore complex protein Nup214 chr9 Census, Compendium Yes 1 intact, hippie, biogrid 217 1479 146 146 2
NXPE1_ENST00000424269 NXPE1 Q8N323 NXPE family member 1 chr11 Not Cancer Driver No 1 intact, hippie 108 23 4 4 0
OLA1 OLA1 Q9NTK5 Obg-like ATPase 1 chr2 Not Cancer Driver No 1 hippie, biogrid 41 40 5 5 0
P4HA2_ENST00000379104 P4HA2 O15460 Prolyl 4-hydroxylase subunit alpha-2 chr5 Not Cancer Driver No 2 hippie, biogrid 66 82 12 12 2
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 3 intact, hippie, biogrid 61 79 15 15 1
PAICS_ENST00000512576 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 Not Cancer Driver No 1 intact, hippie, biogrid 23 35 3 3 0
PALB2 PALB2 Q86YC2 Partner and localizer of BRCA2 chr16 Census Yes 1 hippie, biogrid 124 769 77 77 1
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 11 30 0 0 5
PCDHGB1 PCDHGB1 Q9Y5G3 Protocadherin gamma-B1 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 220 329 61 61 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 intact, hippie, biogrid 30 22 3 3 1
PDCD2L PDCD2L Q9BRP1 Programmed cell death protein 2-like chr19 Not Cancer Driver No 1 hippie, biogrid 35 83 6 6 0
PDIA6_ENST00000272227 PDIA6 Q15084 Protein disulfide-isomerase A6 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 55 82 11 11 0
PGD PGD P52209 6-phosphogluconate dehydrogenase, decarboxylating chr1 Not Cancer Driver No 1 intact, hippie, biogrid 73 19 3 3 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX Not Cancer Driver No 1 hippie, biogrid 61 40 5 5 9
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 Not Cancer Driver No 1 hippie 58 142 23 23 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
PLK4 PLK4 O00444 Serine/threonine-protein kinase PLK4 chr4 Not Cancer Driver No 1 hippie 102 451 45 45 0
POC1A POC1A Q8NBT0 POC1 centriolar protein homolog A chr3 Not Cancer Driver No 1 hippie 51 88 8 8 1
POLR3A POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 155 113 17 17 15
PPEF1 PPEF1 O14829 Serine/threonine-protein phosphatase with EF-hands 1 chrX Not Cancer Driver No 1 intact, hippie 127 66 10 10 0
PRAM1 PRAM1 Q96QH2 PML-RARA-regulated adapter molecule 1 chr19 Not Cancer Driver No 1 intact, hippie 118 628 117 117 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 46 13 4 4 0
PSAT1 PSAT1 Q9Y617 Phosphoserine aminotransferase chr9 Not Cancer Driver No 1 hippie 54 3 1 1 3
PSMC4 PSMC4 P43686 26S proteasome regulatory subunit 6B chr19 Not Cancer Driver No 1 hippie 51 21 3 3 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie, biogrid 23 67 6 6 0
PSMD2 PSMD2 Q13200 26S proteasome non-ATPase regulatory subunit 2 chr3 Not Cancer Driver No 1 intact, hippie 100 135 14 14 0
PSPC1_ENST00000619300 PSPC1 Q8WXF1 Paraspeckle component 1 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 97 367 81 81 0
PTPN21_ENST00000328736 PTPN21 Q16825 Tyrosine-protein phosphatase non-receptor type 21 chr14 Not Cancer Driver No 1 hippie 153 593 91 91 0
PYGO1 PYGO1 Q9Y3Y4 Pygopus homolog 1 chr15 Not Cancer Driver No 1 intact, hippie 71 362 60 60 0
RAB31 RAB31 Q13636 Ras-related protein Rab-31 chr18 Not Cancer Driver No 1 hippie 27 28 11 11 0
RAB3C RAB3C Q96E17 Ras-related protein Rab-3C chr5 Not Cancer Driver No 1 intact, hippie 52 54 10 10 0
RAET1L_ENST00000286380 RAET1L Q5VY80 UL16-binding protein 6 chr6 Not Cancer Driver No 1 hippie, biogrid 30 30 2 2 0
RANBP1_ENST00000331821 RANBP1 P43487 Ran-specific GTPase-activating protein chr22 Not Cancer Driver No 1 intact, hippie, biogrid 19 137 16 16 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 Not Cancer Driver No 1 hippie 26 14 3 3 0
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 Not Cancer Driver No 1 intact, hippie 90 126 44 44 0
RBM17 RBM17 Q96I25 Splicing factor 45 chr10 Not Cancer Driver No 1 hippie 49 293 38 38 0
RBM5 RBM5 P52756 RNA-binding protein 5 chr3 Not Cancer Driver No 1 hippie 94 537 67 67 0
RREB1_ENST00000349384 RREB1 Q92766 Ras-responsive element-binding protein 1 chr6 Not Cancer Driver No 2 intact, hippie 213 1152 144 144 0
SBF1_ENST00000348911 SBF1 O95248 Myotubularin-related protein 5 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 210 632 63 63 2
SCYL1 SCYL1 Q96KG9 N-terminal kinase-like protein chr11 Not Cancer Driver No 1 hippie 85 312 32 32 0
SEC16A SEC16A O15027 Protein transport protein Sec16A chr9 Not Cancer Driver No 1 hippie, biogrid 285 1923 235 235 0
SHARPIN SHARPIN Q9H0F6 Sharpin chr8 Not Cancer Driver No 1 hippie 34 237 16 16 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie, biogrid 57 58 5 5 1
SLC18A2_ENST00000644641 SLC18A2 Q05940 Synaptic vesicular amine transporter chr10 Not Cancer Driver No 1 hippie, biogrid 105 23 7 7 1
SLC1A5 SLC1A5 Q15758 Neutral amino acid transporter B(0) chr19 Not Cancer Driver No 1 hippie, biogrid 52 61 7 7 0
SLC25A11 SLC25A11 Q02978 Mitochondrial 2-oxoglutarate/malate carrier protein chr17 Not Cancer Driver No 1 intact, hippie 37 16 1 1 3
SLC39A9 SLC39A9 Q9NUM3 Zinc transporter ZIP9 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 34 44 4 4 0
SMC1A SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX Census, Compendium Yes 1 intact, hippie, biogrid 200 717 114 114 21
SMC4_ENST00000344722 SMC4 Q9NTJ3 Structural maintenance of chromosomes protein 4 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 175 539 55 55 0
SP6_ENST00000342234 SP6 Q3SY56 Transcription factor Sp6 chr17 Not Cancer Driver No 1 intact, hippie 55 296 39 39 0
SPAG9 SPAG9 O60271 C-Jun-amino-terminal kinase-interacting protein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 128 841 81 81 0
SPATA17 SPATA17 Q96L03 Spermatogenesis-associated protein 17 chr1 Not Cancer Driver No 1 intact, hippie 93 61 17 17 0
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 Not Cancer Driver No 1 intact, hippie 73 228 43 43 0
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 Not Cancer Driver No 1 hippie, biogrid 78 343 46 46 0
SUB1_ENST00000515355 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 Not Cancer Driver No 1 hippie, biogrid 13 108 6 6 0
SULF2_ENST00000484875 SULF2 Q8IWU5 Extracellular sulfatase Sulf-2 chr20 Not Cancer Driver No 1 hippie, biogrid 145 142 18 18 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie, biogrid 9 69 6 6 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie, biogrid 165 572 87 87 0
TBCB TBCB Q99426 Tubulin-folding cofactor B chr19 Not Cancer Driver No 1 hippie, biogrid 30 59 2 2 0
TCOF1 TCOF1 Q13428 Treacle protein chr5 Not Cancer Driver No 1 hippie 142 1454 141 141 1
TDO2 TDO2 P48775 Tryptophan 2,3-dioxygenase chr4 Not Cancer Driver No 1 hippie 64 31 9 9 1
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 Not Cancer Driver No 1 hippie 63 220 34 34 0
THAP7_ENST00000399133 THAP7 Q9BT49 THAP domain-containing protein 7 chr22 Not Cancer Driver No 1 intact, hippie 34 214 24 24 0
THBS3 THBS3 P49746 Thrombospondin-3 chr1 Not Cancer Driver No 1 intact, hippie 100 283 24 24 0
TKT_ENST00000462138 TKT P29401 Transketolase chr3 Not Cancer Driver No 1 intact, hippie, biogrid 66 86 7 7 1
TMEM9_ENST00000485839 TMEM9 Q9P0T7 Proton-transporting V-type ATPase complex assembly regulator TMEM9 chr1 Not Cancer Driver No 1 hippie, biogrid 22 23 3 3 0
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 intact, hippie, biogrid 78 412 52 52 0
TMX3 TMX3 Q96JJ7 Protein disulfide-isomerase TMX3 chr18 Not Cancer Driver No 1 intact, hippie 50 49 9 9 0
TNF TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 2 intact, hippie, biogrid 24 45 3 3 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 Census, Compendium Yes 1 hippie 98 231 33 33 1
TNMD TNMD Q9H2S6 Tenomodulin chrX Not Cancer Driver No 1 intact, hippie 49 44 10 10 0
TPGS2_ENST00000334295 TPGS2 Q68CL5 Tubulin polyglutamylase complex subunit 2 chr18 Not Cancer Driver No 1 hippie 28 107 9 9 0
TPX2 TPX2 Q9ULW0 Targeting protein for Xklp2 chr20 Not Cancer Driver No 1 intact, hippie 92 695 86 86 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 59 225 20 20 0
TRNAU1AP TRNAU1AP Q9NX07 tRNA selenocysteine 1-associated protein 1 chr1 Not Cancer Driver No 1 intact, hippie 28 32 4 4 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 intact, hippie 40 63 11 11 5
TUBGCP3 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 1 hippie, biogrid 109 156 16 16 0
U2AF1 U2AF1 Q01081 Splicing factor U2AF 35 kDa subunit chr21 Census, Compendium Yes 1 intact 70 73 13 13 3
UBA1 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX Not Cancer Driver No 1 hippie, biogrid 117 165 22 22 6
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 hippie, biogrid 84 219 33 33 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 30 32 6 6 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 Not Cancer Driver No 1 hippie, biogrid 25 24 3 3 0
USP12 USP12 O75317 Ubiquitin carboxyl-terminal hydrolase 12 chr13 Not Cancer Driver No 1 intact, hippie 55 33 5 5 0
WARS WARS1 P23381 Tryptophan--tRNA ligase, cytoplasmic chr14 Not Cancer Driver No 1 intact 62 90 13 13 1
WDR19 WDR19 Q8NEZ3 WD repeat-containing protein 19 chr4 Not Cancer Driver No 2 intact, hippie 117 19 0 0 11
WDR35 WDR35 Q9P2L0 WD repeat-containing protein 35 chr2 Not Cancer Driver No 2 intact, hippie 137 42 3 3 6
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 87 118 11 11 0
ZC3H4 ZC3H4 Q9UPT8 Zinc finger CCCH domain-containing protein 4 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 152 1235 145 145 0
ZHX1-C8orf76 ZHX1-C8orf76 Q96EF9 Zinc fingers and homeoboxes protein 1, isoform 2 chr8 Not Cancer Driver No 1 intact, hippie 28 21 0 0 0
ZNF214 ZNF214 Q9UL59 Zinc finger protein 214 chr11 Not Cancer Driver No 1 hippie, biogrid 128 98 22 22 0
ZNF331_ENST00000411977 ZNF331 Q9NQX6 Zinc finger protein 331 chr19 Census Yes 1 intact, hippie, biogrid 122 112 27 27 0
ZNF556 ZNF556 Q9HAH1 Zinc finger protein 556 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 107 177 36 36 0
ZNF669 ZNF669 Q96BR6 Zinc finger protein 669 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 65 81 9 9 0