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NDUFS2 ,NDUFS2 ,O75306
  • Uniprot Accession= O75306
  • Ensembl Transcript= ENST00000367993.7
  • Uniprot Name= NDUFS2
  • Name= NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 53
  • Number of Interaction partner in biogrid: 148
  • Number of Interaction partner in hippie: 254
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 123 203 25 25 5
ACAD9 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 2 intact, hippie, biogrid 69 28 5 5 12
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 Not Cancer Driver No 1 hippie 52 35 4 4 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 1 hippie 126 141 15 15 11
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 intact, hippie 88 166 22 22 11
AKTIP_ENST00000570004 AKTIP Q9H8T0 AKT-interacting protein chr16 Not Cancer Driver No 1 hippie 33 95 10 10 0
ALDOA_ENST00000643777 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 Not Cancer Driver No 1 intact 47 65 9 9 3
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 Not Cancer Driver No 1 hippie 173 788 103 103 0
ANKRD34C ANKRD34C P0C6C1 Ankyrin repeat domain-containing protein 34C chr15 Not Cancer Driver No 1 hippie, biogrid 31 405 26 26 0
AP2B1_ENST00000621914 AP2B1 P63010 AP-2 complex subunit beta chr17 Not Cancer Driver No 1 intact 85 95 12 12 0
APOO APOO Q9BUR5 MICOS complex subunit MIC26 chrX Not Cancer Driver No 1 hippie, biogrid 25 23 4 4 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARMC8_ENST00000469044 ARMC8 Q8IUR7 Armadillo repeat-containing protein 8 chr3 Not Cancer Driver No 1 hippie 71 7 0 0 0
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 60 85 8 8 0
ATP5F1C ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 Not Cancer Driver No 1 hippie 39 11 0 0 0
ATP5PB ATP5PB P24539 ATP synthase F(0) complex subunit B1, mitochondrial chr1 Not Cancer Driver No 1 hippie 37 2 0 0 0
ATP6V1A ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 Not Cancer Driver No 1 hippie, biogrid 86 31 2 2 4
AUH AUH Q13825 Methylglutaconyl-CoA hydratase, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 34 29 0 0 1
AURKAIP1_ENST00000321751 AURKAIP1 Q9NWT8 Aurora kinase A-interacting protein chr1 Not Cancer Driver No 1 hippie 18 104 8 8 0
BCKDHA BCKDHA P12694 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 53 121 18 18 11
BCL2L14 BCL2L14 Q9BZR8 Apoptosis facilitator Bcl-2-like protein 14 chr12 Not Cancer Driver No 1 hippie 29 40 4 4 0
BFAR BFAR Q9NZS9 Bifunctional apoptosis regulator chr16 Not Cancer Driver No 1 hippie 56 30 1 1 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
C15orf48_ENST00000396650 NMES1 Q9C002 Normal mucosa of esophagus-specific gene 1 protein chr15 Not Cancer Driver No 1 intact 14 10 1 1 0
C17orf80_ENST00000535032 C17orf80 Q9BSJ5 Uncharacterized protein C17orf80 chr17 Not Cancer Driver No 1 hippie, biogrid 64 455 53 53 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 103 6 6 2
C8orf82 C8orf82 Q6P1X6 UPF0598 protein C8orf82 chr8 Not Cancer Driver No 1 hippie, biogrid 11 11 0 0 0
CALR CALR P27797 Calreticulin chr19 Census Yes 1 hippie, biogrid 45 245 31 31 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 hippie, biogrid 65 334 38 38 0
CCDC90B CCDC90B Q9GZT6 Coiled-coil domain-containing protein 90B, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 31 76 6 6 0
CENPU CENPU Q71F23 Centromere protein U chr4 Not Cancer Driver No 1 intact, hippie 51 298 42 42 0
CGRRF1 CGRRF1 Q99675 Cell growth regulator with RING finger domain protein 1 chr14 Not Cancer Driver No 1 hippie 31 34 5 5 0
CHCHD1 CHCHD1 Q96BP2 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 11 67 8 8 0
CLPP CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 hippie 22 83 9 9 3
COA3 COA3 Q9Y2R0 Cytochrome c oxidase assembly factor 3 homolog, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 4 57 3 3 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
COQ10A COQ10A Q96MF6 Coenzyme Q-binding protein COQ10 homolog A, mitochondrial chr12 Not Cancer Driver No 1 hippie 27 28 0 0 0
COQ7_ENST00000568985 COQ7 Q99807 5-demethoxyubiquinone hydroxylase, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 27 5 1 1 1
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 43 111 13 13 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 hippie, biogrid 61 84 13 13 0
COX14_ENST00000550654 COX14 Q96I36 Cytochrome c oxidase assembly protein COX14 chr12 Not Cancer Driver No 1 intact, hippie 4 7 0 0 1
COX15 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 48 0 0 0 2
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 2 intact, hippie, biogrid 17 5 1 1 1
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 15 23 6 6 2
COX6C_ENST00000522940 COX6C P09669 Cytochrome c oxidase subunit 6C chr8 Census Yes 1 hippie, biogrid 14 0 0 0 0
COX7A2L COX7A2L O14548 Cytochrome c oxidase subunit 7A-related protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
COX7A2_ENST00000509698 COX7A2 D6RIE3 Cytochrome c oxidase subunit 7A2, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 5 13 3 3 0
COX7C COX7C P15954 Cytochrome c oxidase subunit 7C, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 7 0 0 0 0
COX8A COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CPSF7_ENST00000394888 CPSF7 Q8N684 Cleavage and polyadenylation specificity factor subunit 7 chr11 Not Cancer Driver No 1 hippie, biogrid 55 398 52 52 0
CRYZ_ENST00000340866 CRYZ Q08257 Quinone oxidoreductase chr1 Not Cancer Driver No 1 hippie, biogrid 49 0 0 0 0
CS CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 2 hippie, biogrid 50 13 2 2 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CYC1 CYC1 P08574 Cytochrome c1, heme protein, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 65 35 8 8 2
DDX28 DDX28 Q9NUL7 Probable ATP-dependent RNA helicase DDX28 chr16 Not Cancer Driver No 1 hippie, biogrid 37 127 3 3 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DHRS4 DHRS4 Q9BTZ2 Dehydrogenase/reductase SDR family member 4 chr14 Not Cancer Driver No 2 hippie, biogrid 30 38 4 4 0
DHX30 DHX30 Q7L2E3 ATP-dependent RNA helicase DHX30 chr3 Not Cancer Driver No 1 hippie, biogrid 165 260 40 40 6
DLAT DLAT P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 63 294 42 42 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 67 17 0 0 10
DMWD DMWD Q09019 Dystrophia myotonica WD repeat-containing protein chr19 Not Cancer Driver No 1 hippie, biogrid 66 374 24 24 0
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 21 21 0
DNAJC15 DNAJC15 Q9Y5T4 DnaJ homolog subfamily C member 15 chr13 Not Cancer Driver No 1 hippie, biogrid 19 25 4 4 0
DNAJC19 DNAJC19 Q96DA6 Mitochondrial import inner membrane translocase subunit TIM14 chr3 Not Cancer Driver No 1 hippie, biogrid 19 27 6 6 0
DNAJC28_ENST00000381947 DNAJC28 Q9NX36 DnaJ homolog subfamily C member 28 chr21 Not Cancer Driver No 1 hippie, biogrid 55 139 11 11 0
DNAJC30 DNAJC30 Q96LL9 DnaJ homolog subfamily C member 30, mitochondrial chr7 Not Cancer Driver No 2 hippie, biogrid 25 83 7 7 3
ECI2 ECI2 O75521 Enoyl-CoA delta isomerase 2 chr6 Not Cancer Driver No 1 hippie 52 70 8 8 0
ECSIT ECSIT Q9BQ95 Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 58 146 29 29 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EGR2 EGR2 P11161 E3 SUMO-protein ligase EGR2 chr10 Compendium Yes 1 hippie 90 352 59 59 11
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 107 59 6 6 2
EMC2 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie 48 29 3 3 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 58 176 15 15 0
FAF2 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie 54 171 16 16 0
FAM160A2_ENST00000449352 FHIP1B Q8N612 FHF complex subunit HOOK interacting protein 1B chr11 Not Cancer Driver No 1 intact 129 415 54 54 0
FAM160B2 FHIP2B Q86V87 FHF complex subunit HOOK interacting protein 2B chr8 Not Cancer Driver No 1 intact 75 139 14 14 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FASTKD2_ENST00000402774 FASTKD2 Q9NYY8 FAST kinase domain-containing protein 2, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 74 30 2 2 0
FASTKD3 FASTKD3 Q14CZ7 FAST kinase domain-containing protein 3, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 106 6 1 1 0
FASTKD5 FASTKD5 Q7L8L6 FAST kinase domain-containing protein 5, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 86 94 8 8 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GFM1_ENST00000486715 GFM1 Q96RP9 Elongation factor G, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 74 79 7 7 4
GFM2_ENST00000509430 GFM2 Q969S9 Ribosome-releasing factor 2, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 75 100 10 10 2
GOLT1B GOLT1B Q9Y3E0 Vesicle transport protein GOT1B chr12 Not Cancer Driver No 1 intact, hippie 26 0 0 0 0
GPR45 GPR45 Q9Y5Y3 Probable G-protein coupled receptor 45 chr2 Not Cancer Driver No 1 hippie, biogrid 97 0 0 0 0
GRSF1 GRSF1 Q12849 G-rich sequence factor 1 chr4 Not Cancer Driver No 2 hippie, biogrid 49 147 20 20 0
HADHA HADHA P40939 Trifunctional enzyme subunit alpha, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 72 19 2 2 5
HADHB HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 71 41 9 9 14
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 10 29 2 2 0
HMOX2_ENST00000406590 HMOX2 P30519 Heme oxygenase 2 chr16 Not Cancer Driver No 1 intact, hippie 27 74 10 10 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 2 intact, hippie, biogrid 36 25 6 6 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie, biogrid 94 268 35 35 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie, biogrid 119 141 28 28 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 67 283 26 26 2
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 61 82 6 6 2
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie 44 127 9 9 2
IMMP1L IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 20 3 0 0 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie, biogrid 97 400 50 50 0
IRF2 IRF2 P14316 Interferon regulatory factor 2 chr4 Not Cancer Driver No 1 intact, hippie 85 288 73 73 0
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 70 18 3 3 0
KCND3 KCND3 Q9UK17 Potassium voltage-gated channel subfamily D member 3 chr1 Not Cancer Driver No 1 hippie 172 202 44 44 5
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 61 277 50 50 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
LACTB LACTB P83111 Serine beta-lactamase-like protein LACTB, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 44 121 3 3 0
LMAN2 LMAN2 Q12907 Vesicular integral-membrane protein VIP36 chr5 Not Cancer Driver No 1 hippie, biogrid 53 36 8 8 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 99 175 15 15 10
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 2 hippie, biogrid 131 18 2 2 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 Not Cancer Driver No 1 hippie 22 0 0 0 1
MAIP1 MAIP1 Q8WWC4 m-AAA protease-interacting protein 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 28 12 0 0 0
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 hippie, biogrid 136 589 92 92 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 41 13 0 0 0
MCUB MCUB Q9NWR8 Calcium uniporter regulatory subunit MCUb, mitochondrial chr4 Not Cancer Driver No 1 hippie 33 24 1 1 0
MCUR1 MCUR1 Q96AQ8 Mitochondrial calcium uniporter regulator 1 chr6 Not Cancer Driver No 1 hippie, biogrid 30 65 0 0 0
MDH2 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 39 8 1 1 3
METTL15 METTL15 A6NJ78 12S rRNA N4-methylcytidine (m4C) methyltransferase chr11 Not Cancer Driver No 1 hippie, biogrid 46 92 14 14 0
METTL17_ENST00000339374 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 62 95 16 16 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
MKLN1 MKLN1 Q9UL63 Muskelin chr7 Not Cancer Driver No 2 intact, hippie 85 91 13 13 0
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 Not Cancer Driver No 1 hippie 73 11 0 0 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MRPL11 MRPL11 Q9Y3B7 39S ribosomal protein L11, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 25 12 1 1 0
MRPL58 MRPL58 Q14197 Peptidyl-tRNA hydrolase ICT1, mitochondrial chr17 Not Cancer Driver No 1 hippie 28 105 13 13 0
MRPS12_ENST00000402029 MRPS12 O15235 28S ribosomal protein S12, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 18 59 11 11 0
MRPS21_ENST00000614145 MRPS21 P82921 28S ribosomal protein S21, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 18 0 0 0 0
MRPS26 MRPS26 Q9BYN8 28S ribosomal protein S26, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 18 102 6 6 0
MRRF MRRF Q96E11 Ribosome-recycling factor, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 23 118 9 9 0
MTCH1 MTCH1 Q9NZJ7 Mitochondrial carrier homolog 1 chr6 Not Cancer Driver No 1 hippie, biogrid 31 102 2 2 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 2 hippie, biogrid 45 11 0 0 0
MTERF3 MTERF3 Q96E29 Transcription termination factor 3, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 53 62 5 5 0
MTFMT MTFMT Q96DP5 Methionyl-tRNA formyltransferase, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 35 56 3 3 3
MTG1 MTG1 Q9BT17 Mitochondrial ribosome-associated GTPase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 43 16 3 3 0
MTG2 MTG2 Q9H4K7 Mitochondrial ribosome-associated GTPase 2 chr20 Not Cancer Driver No 1 hippie, biogrid 57 47 9 9 0
MTIF2_ENST00000403721 MTIF2 P46199 Translation initiation factor IF-2, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 101 112 9 9 0
MTIF3_ENST00000381120 MTIF3 Q9H2K0 Translation initiation factor IF-3, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 26 180 19 19 0
MTRF1 MTRF1 O75570 Peptide chain release factor 1, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 50 71 9 9 0
MTRF1L MTRF1L Q9UGC7 Peptide chain release factor 1-like, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 31 183 12 12 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYL12A_ENST00000217652 MYL12A P19105 Myosin regulatory light chain 12A chr18 Not Cancer Driver No 1 hippie, biogrid 19 70 13 13 0
NDUFA1 NDUFA1 O15239 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 chrX Not Cancer Driver No 1 hippie, biogrid 14 0 0 0 2
NDUFA10 NDUFA10 O95299 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 48 19 0 0 1
NDUFA11_ENST00000308961 NDUFA11 Q86Y39 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 chr19 Not Cancer Driver No 1 intact, hippie 6 0 0 0 0
NDUFA12 NDUFA12 Q9UI09 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 chr12 Not Cancer Driver No 1 intact, hippie 18 31 6 6 0
NDUFA13 NDUFA13 Q9P0J0 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 29 24 4 4 1
NDUFA2 NDUFA2 O43678 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 chr5 Not Cancer Driver No 2 intact, hippie 10 0 0 0 0
NDUFA4 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 hippie, biogrid 14 4 0 0 0
NDUFA6_ENST00000602404 NDUFA6 P56556 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 chr22 Not Cancer Driver No 1 hippie 10 14 2 2 1
NDUFA7 NDUFA7 O95182 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 chr19 Not Cancer Driver No 1 hippie, biogrid 16 103 13 13 0
NDUFA8 NDUFA8 P51970 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 25 33 1 1 2
NDUFA9 NDUFA9 Q16795 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial chr12 Not Cancer Driver No 3 hippie, biogrid 57 8 0 0 2
NDUFAB1_ENST00000007516 NDUFAB1 O14561 Acyl carrier protein, mitochondrial chr16 Not Cancer Driver No 1 intact 23 0 0 0 0
NDUFAF3 NDUFAF3 Q9BU61 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 chr3 Not Cancer Driver No 2 intact, hippie 20 33 3 3 3
NDUFAF4 NDUFAF4 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 14 46 4 4 2
NDUFAF5 NDUFAF5 Q5TEU4 Arginine-hydroxylase NDUFAF5, mitochondrial chr20 Not Cancer Driver No 1 hippie 47 69 15 15 3
NDUFAF7 NDUFAF7 Q7L592 Protein arginine methyltransferase NDUFAF7, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 53 19 3 3 0
NDUFB11_ENST00000377811 NDUFB11 Q9NX14 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial chrX Not Cancer Driver No 2 intact, hippie, biogrid 26 51 6 6 1
NDUFB3 NDUFB3 O43676 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 chr2 Not Cancer Driver No 1 hippie, biogrid 15 17 1 1 1
NDUFB5 NDUFB5 O43674 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 28 9 1 1 0
NDUFS1_ENST00000449699 NDUFS1 P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial chr2 Not Cancer Driver No 3 hippie, biogrid 81 40 3 3 2
NDUFS3 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 Not Cancer Driver No 10 intact, hippie, biogrid 34 26 3 3 2
NDUFS4 NDUFS4 O43181 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 26 92 17 17 1
NDUFS5_ENST00000372967 NDUFS5 O43920 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 15 31 3 3 0
NDUFS6 NDUFS6 O75380 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial chr5 Not Cancer Driver No 3 hippie, biogrid 20 8 0 0 1
NDUFS7 NDUFS7 O75251 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial chr19 Not Cancer Driver No 2 hippie, biogrid 36 30 3 3 1
NDUFS8 NDUFS8 O00217 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial chr11 Not Cancer Driver No 2 hippie, biogrid 27 37 2 2 3
NDUFV1 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 Not Cancer Driver No 3 hippie, biogrid 66 57 9 9 3
NDUFV2 NDUFV2 P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial chr18 Not Cancer Driver No 4 hippie, biogrid 40 69 15 15 0
NDUFV3_ENST00000340344 NDUFV3 P56181 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial chr21 Not Cancer Driver No 1 hippie, biogrid 5 95 4 4 0
NGRN NGRN Q9NPE2 Neugrin chr15 Not Cancer Driver No 1 hippie, biogrid 26 215 21 21 0
NIT1 NIT1 Q86X76 Deaminated glutathione amidase chr1 Not Cancer Driver No 1 hippie 41 18 3 3 0
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 78 47 8 8 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NT5C3A NT5C3A Q9H0P0 Cytosolic 5'-nucleotidase 3A chr7 Compendium Yes 1 intact, hippie 44 0 0 0 8
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 37 169 25 25 0
OGDH OGDH Q02218 2-oxoglutarate dehydrogenase complex component E1 chr7 Not Cancer Driver No 1 hippie, biogrid 150 106 19 19 0
OMA1 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 52 34 4 4 0
OPA3_ENST00000263275 OPA3 Q9H6K4 Optic atrophy 3 protein chr19 Not Cancer Driver No 1 hippie 18 44 7 7 2
OSMR OSMR Q99650 Oncostatin-M-specific receptor subunit beta chr5 Not Cancer Driver No 1 hippie 167 145 22 22 5
OTC OTC P00480 Ornithine transcarbamylase, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 89 24 4 4 111
OTULINL OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 59 21 0 0 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 50 10 5 5 0
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 49 28 5 5 0
PCCB_ENST00000251654 PCCB P05166 Propionyl-CoA carboxylase beta chain, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 59 64 12 12 25
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 intact, hippie 30 22 3 3 1
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 2 hippie, biogrid 70 43 6 6 20
PDHB PDHB P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 32 4 0 0 2
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 52 50 10 10 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 31 26 4 4 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 Not Cancer Driver No 1 intact 37 4 1 1 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 152 919 121 121 0
PMPCA PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie, biogrid 67 23 3 3 4
PMPCB PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 1 hippie, biogrid 55 22 3 3 5
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 Census Yes 1 hippie 36 186 12 12 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 Not Cancer Driver No 1 hippie 37 0 0 0 23
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PTPMT1 PTPMT1 Q8WUK0 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 chr11 Not Cancer Driver No 1 intact, hippie 16 0 0 0 0
RAB5IF_ENST00000373852 RAB5IF Q9BUV8 Respirasome Complex Assembly Factor 1 chr20 Not Cancer Driver No 1 hippie 7 13 0 0 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 intact, hippie 66 2 1 1 6
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RMND1 RMND1 Q9NWS8 Required for meiotic nuclear division protein 1 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 46 83 11 11 1
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
RPUSD3 RPUSD3 Q6P087 Mitochondrial mRNA pseudouridine synthase RPUSD3 chr3 Not Cancer Driver No 1 hippie, biogrid 33 85 5 5 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 54 97 15 15 0
SCCPDH SCCPDH Q8NBX0 Saccharopine dehydrogenase-like oxidoreductase chr1 Not Cancer Driver No 1 hippie, biogrid 56 26 1 1 0
SCO1 SCO1 O75880 Protein SCO1 homolog, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 35 79 7 7 1
SDHA SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 1 hippie, biogrid 115 71 13 13 7
SDHC SDHC Q99643 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial chr1 Census Yes 1 hippie, biogrid 16 0 0 0 0
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 intact, hippie 31 29 1 1 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 58 5 5 1
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
SLC25A51_ENST00000242275 SLC25A51 Q9H1U9 Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 chr9 Not Cancer Driver No 1 hippie, biogrid 31 21 0 0 0
SLIRP SLIRP Q9GZT3 SRA stem-loop-interacting RNA-binding protein, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 7 41 3 3 0
SPATA20_ENST00000356488 SPATA20 Q8TB22 Spermatogenesis-associated protein 20 chr17 Not Cancer Driver No 1 hippie 101 162 19 19 0
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 Not Cancer Driver No 1 hippie, biogrid 68 99 17 17 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 intact, hippie 54 267 32 32 30
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 27 0 0 0 6
SURF1 SURF1 Q15526 Surfeit locus protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 17 82 6 6 11
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 Not Cancer Driver No 1 hippie 63 284 32 32 0
TACO1 TACO1 Q9BSH4 Translational activator of cytochrome c oxidase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 21 111 2 2 0
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 74 60 2 2 0
TCTN3 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 intact, hippie 45 71 8 8 1
TEFM TEFM Q96QE5 Transcription elongation factor, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 37 26 5 5 0
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 Not Cancer Driver No 2 hippie, biogrid 25 110 15 15 1
TIMM29 TIMM29 Q9BSF4 Mitochondrial import inner membrane translocase subunit Tim29 chr19 Not Cancer Driver No 1 hippie 9 4 0 0 0
TIMMDC1 TIMMDC1 Q9NPL8 Complex I assembly factor TIMMDC1, mitochondrial chr3 Not Cancer Driver No 2 hippie, biogrid 44 50 6 6 0
TMEM70 TMEM70 Q9BUB7 Transmembrane protein 70, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 26 24 4 4 1
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 Not Cancer Driver No 1 hippie 55 174 17 17 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 Census, Compendium Yes 1 intact, hippie 33 54 8 8 0
TOMM22 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 18 83 9 9 0
TOMM40_ENST00000405636 TOMM40 O96008 Mitochondrial import receptor subunit TOM40 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 17 98 1 1 0
TOMM5_ENST00000321301 TOMM5 Q8N4H5 Mitochondrial import receptor subunit TOM5 homolog chr9 Not Cancer Driver No 1 hippie, biogrid 4 0 0 0 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 74 110 11 11 0
TRMT61B TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 48 123 10 10 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 37 73 7 7 0
TSFM_ENST00000454289 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 37 74 7 7 2
TUFM TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 51 50 3 3 1
UBD UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 31 8 1 1 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 1 intact, hippie 57 127 5 5 0
UQCRC1 UQCRC1 P31930 Cytochrome b-c1 complex subunit 1, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 57 55 6 6 2
UQCRC2 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 53 48 13 13 1
UQCRQ_ENST00000378665 UQCRQ O14949 Cytochrome b-c1 complex subunit 8 chr5 Not Cancer Driver No 1 hippie, biogrid 9 12 1 1 1
VAPA_ENST00000400000 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 intact, hippie 24 184 14 14 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 38 36 4 4 0
VDAC2_ENST00000543351 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 35 9 1 1 0
VDAC3_ENST00000022615 VDAC3 Q9Y277 Voltage-dependent anion-selective channel protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 24 0 0 0 0
VWA8 VWA8 A3KMH1 von Willebrand factor A domain-containing protein 8 chr13 Not Cancer Driver No 1 hippie, biogrid 246 384 36 36 0
ZNF782 ZNF782 Q6ZMW2 Zinc finger protein 782 chr9 Not Cancer Driver No 1 hippie, biogrid 106 294 50 50 0