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NCSTN ,NCSTN ,Q92542
  • Uniprot Accession= Q92542
  • Ensembl Transcript= ENST00000294785.9
  • Uniprot Name= NCSTN
  • Name= Nicastrin
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 54
  • Number of Interaction partner in biogrid: 93
  • Number of Interaction partner in hippie: 177
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 2 intact, hippie, biogrid 70 48 14 14 84
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 Not Cancer Driver No 1 intact, hippie 88 156 20 20 4
AHNAK2 AHNAK2 Q8IVF2 Protein AHNAK2 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 1074 5470 1018 1018 0
ALDOA_ENST00000643777 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 Not Cancer Driver No 1 hippie 47 65 9 9 3
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 Not Cancer Driver No 2 intact, hippie, biogrid 129 16 2 2 0
APH1A APH1A Q96BI3 Gamma-secretase subunit APH-1A chr1 Not Cancer Driver No 4 intact, hippie 32 0 0 0 0
APH1B APH1B Q8WW43 Gamma-secretase subunit APH-1B chr15 Not Cancer Driver No 1 hippie 21 0 0 0 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 intact, hippie 115 115 16 16 6
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 Not Cancer Driver No 1 intact, hippie 136 78 14 14 41
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 intact, hippie 66 23 5 5 2
ATP6V1A ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 Not Cancer Driver No 1 hippie 86 31 2 2 4
ATP6V1B1 ATP6V1B1 P15313 V-type proton ATPase subunit B, kidney isoform chr2 Not Cancer Driver No 1 hippie 77 66 14 14 9
BACE1 BACE1 P56817 Beta-secretase 1 chr11 Not Cancer Driver No 1 hippie 55 53 5 5 0
BCAS2 BCAS2 O75934 Pre-mRNA-splicing factor SPF27 chr1 Not Cancer Driver No 1 hippie, biogrid 30 55 5 5 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 Not Cancer Driver No 1 hippie, biogrid 94 75 21 21 0
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie 43 123 17 17 0
C1orf198 C1orf198 Q9H425 Uncharacterized protein C1orf198 chr1 Not Cancer Driver No 1 hippie, biogrid 40 303 36 36 0
CALR CALR P27797 Calreticulin chr19 Census Yes 1 intact 45 245 31 31 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact, hippie 65 334 38 38 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CLEC2B CLEC2B Q92478 C-type lectin domain family 2 member B chr12 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 0
CLPTM1L CLPTM1L Q96KA5 Cleft lip and palate transmembrane protein 1-like protein chr5 Not Cancer Driver No 1 hippie 83 38 4 4 0
COMMD5 COMMD5 Q9GZQ3 COMM domain-containing protein 5 chr8 Not Cancer Driver No 1 hippie, biogrid 30 32 3 3 0
CRNKL1 CRNKL1 Q9BZJ0 Crooked neck-like protein 1 chr20 Census, Compendium Yes 1 intact, hippie 123 241 38 38 0
CSNK1G3_ENST00000361991 CSNK1G3 Q9Y6M4 Casein kinase I isoform gamma-3 chr5 Not Cancer Driver No 1 hippie, biogrid 61 151 22 22 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 Not Cancer Driver No 1 intact, hippie 102 485 61 61 4
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DLK1 DLK1 P80370 Protein delta homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 81 0 0 0 0
DNER DNER Q8NFT8 Delta and Notch-like epidermal growth factor-related receptor chr2 Not Cancer Driver No 1 hippie 162 106 26 26 0
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 hippie, biogrid 67 179 30 30 5
DSG2 DSG2 Q14126 Desmoglein-2 chr18 Not Cancer Driver No 1 hippie 173 476 68 68 5
EBP EBP Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase chrX Not Cancer Driver No 1 intact, hippie 30 9 0 0 9
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 74 121 17 17 3
EEPD1 EEPD1 Q7L9B9 Endonuclease/exonuclease/phosphatase family domain-containing protein 1 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 86 249 32 32 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ELL2 ELL2 O00472 RNA polymerase II elongation factor ELL2 chr5 Not Cancer Driver No 1 intact, hippie 90 421 63 63 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 hippie, biogrid 171 187 39 39 3
ERLIN2_ENST00000519638 ERLIN2 O94905 Erlin-2 chr8 Not Cancer Driver No 2 intact, hippie 38 22 3 3 0
ESYT2_ENST00000613624 ESYT2 A0FGR8 Extended synaptotagmin-2 chr7 Not Cancer Driver No 1 intact, hippie 94 376 25 25 0
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie 94 646 93 93 0
FAM111A FAM111A Q96PZ2 Serine protease FAM111A chr11 Not Cancer Driver No 1 intact, hippie 78 169 23 23 5
FAM19A1_ENST00000496687 TAFA1 Q7Z5A9 Chemokine-like protein TAFA-1 chr3 Not Cancer Driver No 1 hippie 50 6 1 1 0
FASTKD5 FASTKD5 Q7L8L6 FAST kinase domain-containing protein 5, mitochondrial chr20 Not Cancer Driver No 1 intact, hippie 86 94 8 8 0
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 21 75 1 1 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 1 intact, hippie 56 20 3 3 0
FTSJ3 FTSJ3 Q8IY81 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 chr17 Not Cancer Driver No 1 hippie, biogrid 103 533 66 66 0
GAP43_ENST00000305124 GAP43 P17677 Neuromodulin chr3 Not Cancer Driver No 1 intact, hippie 79 238 79 79 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 intact, hippie 115 854 96 96 0
GSAP GSAP A4D1B5 Gamma-secretase-activating protein chr7 Not Cancer Driver No 1 hippie 89 13 0 0 0
GTF3C1 GTF3C1 Q12789 General transcription factor 3C polypeptide 1 chr16 Not Cancer Driver No 1 hippie, biogrid 323 735 114 114 0
HLA-DQB1 HLA-DQB1 Q5SU54 HLA class II histocompatibility antigen, DQ beta 1 chain chr6 Not Cancer Driver No 1 hippie, biogrid 45 48 4 4 0
HNRNPF_ENST00000356053 HNRNPF P52597 Heterogeneous nuclear ribonucleoprotein F chr10 Not Cancer Driver No 1 hippie, biogrid 65 105 18 18 0
HNRNPR_ENST00000374612 HNRNPR O43390 Heterogeneous nuclear ribonucleoprotein R chr1 Not Cancer Driver No 1 hippie, biogrid 67 304 25 25 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 hippie, biogrid 77 504 45 45 0
IK IK Q13123 Protein Red chr5 Not Cancer Driver No 1 hippie, biogrid 61 482 50 50 0
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 intact, hippie 97 400 50 50 0
KHDRBS1 KHDRBS1 Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 53 362 43 43 0
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 Not Cancer Driver No 1 hippie, biogrid 37 0 0 0 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie 47 93 10 10 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie, biogrid 43 55 7 7 1
LGALS3 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 1 hippie 15 133 6 6 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 54 65 16 16 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LMNB1 LMNB1 P20700 Lamin-B1 chr5 Not Cancer Driver No 1 hippie, biogrid 60 404 42 42 4
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 Not Cancer Driver No 1 hippie 22 0 0 0 1
MAGED2 MAGED2 Q9UNF1 Melanoma-associated antigen D2 chrX Not Cancer Driver No 1 hippie 99 326 53 53 1
MAGT1_ENST00000618282 MAGT1 Q9H0U3 Magnesium transporter protein 1 chrX Not Cancer Driver No 1 hippie 63 0 0 0 1
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 Not Cancer Driver No 1 hippie 59 90 8 8 0
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 76 446 42 42 0
MICAL1_ENST00000358807 MICAL1 Q8TDZ2 [F-actin]-monooxygenase MICAL1 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 112 364 37 37 0
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 Not Cancer Driver No 1 intact, hippie 73 11 0 0 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 Not Cancer Driver No 1 hippie, biogrid 144 463 47 47 0
NCAM1_ENST00000316851 NCAM1 P13591 Neural cell adhesion molecule 1 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 207 290 70 70 0
NDUFA9 NDUFA9 Q16795 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 8 0 0 2
NDUFB5 NDUFB5 O43674 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 28 9 1 1 0
NOP16_ENST00000614830 NOP16 Q9Y3C1 Nucleolar protein 16 chr5 Not Cancer Driver No 1 hippie, biogrid 19 118 12 12 0
NOP2_ENST00000322166 NOP2 P46087 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase chr12 Not Cancer Driver No 1 hippie, biogrid 116 510 72 72 0
NOP56 NOP56 O00567 Nucleolar protein 56 chr20 Not Cancer Driver No 1 hippie, biogrid 83 191 34 34 0
NOP58 NOP58 Q9Y2X3 Nucleolar protein 58 chr2 Not Cancer Driver No 1 hippie, biogrid 47 156 14 14 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 155 24 0 0 150
NPR1 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 Not Cancer Driver No 1 intact, hippie 141 78 16 16 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 Census, Compendium Yes 1 hippie, biogrid 234 1864 203 203 0
PAG1 PAG1 Q9NWQ8 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 58 394 54 54 0
PCDHA2 PCDHA2 Q9Y5H9 Protocadherin alpha-2 chr5 Not Cancer Driver No 1 hippie, biogrid 335 270 75 75 0
PHGDH_ENST00000641023 PHGDH O43175 D-3-phosphoglycerate dehydrogenase chr1 Not Cancer Driver No 1 hippie, biogrid 51 38 4 4 8
PLD3_ENST00000409735 PLD3 Q8IV08 5'-3' exonuclease PLD3 chr19 Not Cancer Driver No 1 biogrid 70 62 7 7 0
PLD4_ENST00000392593 PLD4 Q96BZ4 5'-3' exonuclease PLD4 chr14 Not Cancer Driver No 1 biogrid 46 76 10 10 0
PLXDC2 PLXDC2 Q6UX71 Plexin domain-containing protein 2 chr10 Not Cancer Driver No 1 intact, hippie 151 150 50 50 0
PNKD PNKD Q8N490 Probable hydrolase PNKD chr2 Not Cancer Driver No 1 intact, hippie 52 160 25 25 2
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie, biogrid 83 694 57 57 0
PRPF6 PRPF6 O94906 Pre-mRNA-processing factor 6 chr20 Not Cancer Driver No 1 hippie, biogrid 140 379 62 62 1
PRSS21 PRSS21 Q9Y6M0 Testisin chr16 Not Cancer Driver No 1 hippie 41 6 0 0 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 Not Cancer Driver No 7 intact, hippie 61 134 21 21 96
PSEN2 PSEN2 P49810 Presenilin-2 chr1 Not Cancer Driver No 1 hippie 68 89 16 16 7
PSENEN_ENST00000222266 PSENEN Q9NZ42 Gamma-secretase subunit PEN-2 chr19 Not Cancer Driver No 1 hippie 17 0 0 0 0
PSIP1_ENST00000380738 PSIP1 O75475 PC4 and SFRS1-interacting protein chr9 Census, Compendium Yes 1 hippie, biogrid 75 481 71 71 0
PTPRG PTPRG P23470 Receptor-type tyrosine-protein phosphatase gamma chr3 Not Cancer Driver No 1 intact, hippie, biogrid 212 465 61 61 0
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 Not Cancer Driver No 1 hippie 204 137 34 34 0
RAB31 RAB31 Q13636 Ras-related protein Rab-31 chr18 Not Cancer Driver No 1 hippie, biogrid 27 28 11 11 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 Not Cancer Driver No 1 hippie, biogrid 157 730 84 84 0
RAP2A RAP2A P10114 Ras-related protein Rap-2a chr13 Not Cancer Driver No 1 hippie, biogrid 15 9 0 0 0
RBM25 RBM25 P49756 RNA-binding protein 25 chr14 Not Cancer Driver No 1 hippie, biogrid 124 549 88 88 0
RCC1_ENST00000373833 RCC1 P18754 Regulator of chromosome condensation chr1 Not Cancer Driver No 1 hippie, biogrid 54 143 15 15 0
RCC2 RCC2 Q9P258 Protein RCC2 chr1 Not Cancer Driver No 1 hippie, biogrid 63 194 27 27 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 Census, Compendium Yes 1 hippie 208 105 12 12 139
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 Not Cancer Driver No 1 hippie, biogrid 58 50 8 8 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RPP38_ENST00000378202 RPP38 P78345 Ribonuclease P protein subunit p38 chr10 Not Cancer Driver No 1 intact, hippie 36 118 19 19 0
RPS11 RPS11 P62280 40S ribosomal protein S11 chr19 Not Cancer Driver No 1 hippie, biogrid 18 6 0 0 0
RPS14_ENST00000521466 RPS14 P62263 40S ribosomal protein S14 chr5 Not Cancer Driver No 1 hippie, biogrid 14 96 13 13 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 Not Cancer Driver No 1 hippie, biogrid 29 39 7 7 0
RRAS RRAS P10301 Ras-related protein R-Ras chr19 Not Cancer Driver No 1 intact, hippie, biogrid 25 71 6 6 0
RRP7A RRP7A Q9Y3A4 Ribosomal RNA-processing protein 7 homolog A chr22 Not Cancer Driver No 1 hippie, biogrid 25 97 14 14 1
RRS1 RRS1 Q15050 Ribosome biogenesis regulatory protein homolog chr8 Not Cancer Driver No 1 hippie, biogrid 23 315 18 18 0
RSL1D1 RSL1D1 O76021 Ribosomal L1 domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 61 275 33 33 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 Not Cancer Driver No 1 hippie, biogrid 18 76 7 7 0
SAFB_ENST00000292123 SAFB Q15424 Scaffold attachment factor B1 chr19 Not Cancer Driver No 1 hippie, biogrid 111 911 110 110 0
SAP18_ENST00000607003 SAP18 O00422 Histone deacetylase complex subunit SAP18 chr13 Not Cancer Driver No 1 hippie, biogrid 18 99 14 14 0
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 71 685 63 63 0
SCAMP3 SCAMP3 O14828 Secretory carrier-associated membrane protein 3 chr1 Not Cancer Driver No 1 intact, hippie 46 130 23 23 0
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 intact, hippie 31 29 1 1 0
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 Not Cancer Driver No 1 intact, hippie 110 21 7 7 2
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SLC27A2 SLC27A2 O14975 Very long-chain acyl-CoA synthetase chr15 Not Cancer Driver No 1 hippie, biogrid 95 4 0 0 0
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 Not Cancer Driver No 1 hippie 51 13 2 2 48
SLC2A3 SLC2A3 P11169 Solute carrier family 2, facilitated glucose transporter member 3 chr12 Not Cancer Driver No 1 hippie 96 33 11 11 0
SLC7A5 SLC7A5 Q01650 Large neutral amino acids transporter small subunit 1 chr16 Not Cancer Driver No 1 intact, hippie 62 35 1 1 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 hippie 198 195 17 17 8
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 Not Cancer Driver No 1 hippie, biogrid 116 363 48 48 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 1 hippie, biogrid 64 141 35 35 3
SMARCC2_ENST00000267064 SMARCC2 Q8TAQ2 SWI/SNF complex subunit SMARCC2 chr12 Not Cancer Driver No 1 hippie, biogrid 175 876 133 133 4
SMU1 SMU1 Q2TAY7 WD40 repeat-containing protein SMU1 chr9 Not Cancer Driver No 1 hippie, biogrid 50 15 0 0 0
SNRPD2_ENST00000588301 SNRPD2 P62316 Small nuclear ribonucleoprotein Sm D2 chr19 Not Cancer Driver No 1 hippie, biogrid 19 67 12 12 0
SPP1 SPP1 P10451 Osteopontin chr4 Not Cancer Driver No 1 hippie 56 296 54 54 0
SPTLC1 SPTLC1 O15269 Serine palmitoyltransferase 1 chr9 Not Cancer Driver No 1 hippie 50 27 5 5 5
SQOR_ENST00000568606 SQOR Q9Y6N5 Sulfide:quinone oxidoreductase, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie 54 41 8 8 1
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 2 intact, hippie, biogrid 53 130 11 11 1
SRPRB SRPRB Q9Y5M8 Signal recognition particle receptor subunit beta chr3 Not Cancer Driver No 1 intact, hippie 30 23 3 3 0
SRSF1 SRSF1 Q07955 Serine/arginine-rich splicing factor 1 chr17 Not Cancer Driver No 1 hippie, biogrid 41 198 34 34 0
SRSF10 SRSF10 O75494 Serine/arginine-rich splicing factor 10 chr1 Not Cancer Driver No 1 hippie, biogrid 2 192 1 1 0
SRSF11 SRSF11 Q05519 Serine/arginine-rich splicing factor 11 chr1 Not Cancer Driver No 1 hippie, biogrid 63 362 55 55 0
SSRP1 SSRP1 Q08945 FACT complex subunit SSRP1 chr11 Not Cancer Driver No 1 hippie, biogrid 92 308 35 35 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 Not Cancer Driver No 1 intact, hippie 97 111 23 23 18
SUPT16H SUPT16H Q9Y5B9 FACT complex subunit SPT16 chr14 Not Cancer Driver No 1 hippie, biogrid 147 301 44 44 0
SURF4 SURF4 O15260 Surfeit locus protein 4 chr9 Not Cancer Driver No 1 hippie, biogrid 29 0 0 0 0
SYNE3 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 143 236 42 42 0
TCTN3 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 intact, hippie 45 71 8 8 1
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 intact, hippie 51 399 46 46 0
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 Census Yes 1 hippie, biogrid 137 955 137 137 0
TIMM29 TIMM29 Q9BSF4 Mitochondrial import inner membrane translocase subunit Tim29 chr19 Not Cancer Driver No 1 intact, hippie 9 4 0 0 0
TMED10 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 Not Cancer Driver No 1 hippie 24 15 3 3 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 Not Cancer Driver No 1 intact, hippie 24 25 4 4 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 31 56 4 4 1
TMEM14B_ENST00000379542 TMEM14B Q9NUH8 Transmembrane protein 14B chr6 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 95 5 0 0 0
TOMM20 TOMM20 Q15388 Mitochondrial import receptor subunit TOM20 homolog chr1 Not Cancer Driver No 1 hippie 8 25 1 1 0
TOP1 TOP1 P11387 DNA topoisomerase 1 chr20 Census, Compendium Yes 1 hippie, biogrid 93 391 53 53 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 Not Cancer Driver No 1 hippie, biogrid 154 543 46 46 0
TPBG_ENST00000543496 TPBG Q13641 Trophoblast glycoprotein chr6 Not Cancer Driver No 1 hippie, biogrid 58 13 1 1 0
TRA2A TRA2A Q13595 Transformer-2 protein homolog alpha chr7 Not Cancer Driver No 1 hippie, biogrid 45 253 41 41 0
TRIM55 TRIM55 Q9BYV6 Tripartite motif-containing protein 55 chr8 Not Cancer Driver No 1 hippie, biogrid 134 276 78 78 0
TRIP13 TRIP13 Q15645 Pachytene checkpoint protein 2 homolog chr5 Not Cancer Driver No 1 intact, hippie 62 30 6 6 1
TRMT112 TRMT112 Q9UI30 Multifunctional methyltransferase subunit TRM112-like protein chr11 Not Cancer Driver No 1 hippie, biogrid 15 17 2 2 0
TRMT6 TRMT6 Q9UJA5 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 chr20 Not Cancer Driver No 1 intact, hippie 42 208 17 17 0
TTI1 TTI1 O43156 TELO2-interacting protein 1 homolog chr20 Not Cancer Driver No 1 intact, hippie 136 93 13 13 0
U2AF1 U2AF1 Q01081 Splicing factor U2AF 35 kDa subunit chr21 Census, Compendium Yes 1 hippie, biogrid 70 73 13 13 3
USP39 USP39 Q53GS9 U4/U6.U5 tri-snRNP-associated protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 58 128 10 10 0
UTP14A UTP14A Q9BVJ6 U3 small nucleolar RNA-associated protein 14 homolog A chrX Not Cancer Driver No 1 hippie, biogrid 105 629 89 89 0
VASN VASN Q6EMK4 Vasorin chr16 Not Cancer Driver No 3 intact, hippie, biogrid 37 233 8 8 0
VIPR1 VIPR1 P32241 Vasoactive intestinal polypeptide receptor 1 chr3 Not Cancer Driver No 1 hippie, biogrid 41 10 2 2 0
WDR18 WDR18 Q9BV38 WD repeat-containing protein 18 chr19 Not Cancer Driver No 1 hippie, biogrid 38 60 2 2 0
WLS_ENST00000262348 WLS Q5T9L3 Protein wntless homolog chr1 Not Cancer Driver No 1 intact, hippie 71 14 3 3 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie, biogrid 65 62 10 10 0
YIF1A YIF1A O95070 Protein YIF1A chr11 Not Cancer Driver No 1 hippie 32 33 3 3 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie, biogrid 139 929 134 134 0