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NAV1 ,NAV1 ,Q8NEY1
  • Number of Interaction partner in intact: 37
  • Number of Interaction partner in biogrid: 54
  • Number of Interaction partner in hippie: 0
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AMOT AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 1 biogrid 161 909 128 128 0
AP2B1_ENST00000621914 AP2B1 P63010 AP-2 complex subunit beta chr17 Not Cancer Driver No 1 biogrid 85 95 12 12 0
APC APC P25054 Adenomatous polyposis coli protein chr5 Census, Compendium Yes 1 intact 412 2406 345 345 22
APLNR APLNR P35414 Apelin receptor chr11 Not Cancer Driver No 1 biogrid 96 29 8 8 0
BACE2 BACE2 Q9Y5Z0 Beta-secretase 2 chr21 Not Cancer Driver No 1 biogrid 61 23 2 2 0
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 Not Cancer Driver No 1 biogrid 12 111 11 11 0
BRK1 BRK1 Q8WUW1 Protein BRICK1 chr3 Not Cancer Driver No 1 biogrid 7 14 1 1 0
C12orf74_ENST00000544406 C12orf74 Q6ZR37-3 Isoform 3 of Pleckstrin homology domain-containing family G member 7 chr12 Not Cancer Driver No 1 biogrid 29 159 26 26 0
CBY1_ENST00000216029 CBY1 Q9Y3M2 Protein chibby homolog 1 chr22 Not Cancer Driver No 1 intact 13 98 11 11 0
CCT8L2 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 Not Cancer Driver No 1 biogrid 216 104 46 46 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 Not Cancer Driver No 1 biogrid 50 26 5 5 0
CDC25C CDC25C P30307 M-phase inducer phosphatase 3 chr5 Not Cancer Driver No 1 intact 61 224 26 26 0
CEP135 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 Not Cancer Driver No 1 biogrid 127 690 72 72 0
CGN CGN Q9P2M7 Cingulin chr1 Not Cancer Driver No 1 intact 152 1179 149 149 0
COG6 COG6 Q9Y2V7 Conserved oligomeric Golgi complex subunit 6 chr13 Not Cancer Driver No 2 intact, biogrid 83 141 16 16 1
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 1 biogrid 172 817 111 111 11
DENND4C_ENST00000602925 DENND4C Q5VZ89 DENN domain-containing protein 4C chr9 Not Cancer Driver No 1 intact 190 710 69 69 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 2 intact, biogrid 132 514 82 82 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 Not Cancer Driver No 3 intact, biogrid 49 210 25 25 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 Compendium Yes 1 biogrid 70 273 34 34 0
EIF4E2 EIF4E2 O60573 Eukaryotic translation initiation factor 4E type 2 chr2 Not Cancer Driver No 1 intact 27 80 5 5 0
ERP29 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 Not Cancer Driver No 1 intact 29 34 5 5 0
FGFR1OP CEP43 O95684 Centrosomal protein 43 chr6 Not Cancer Driver No 1 intact 43 272 33 33 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 biogrid 71 160 25 25 0
FPR1_ENST00000304748 FPR1 P21462 fMet-Leu-Phe receptor chr19 Not Cancer Driver No 1 biogrid 99 18 3 3 0
GOLGA1 GOLGA1 Q92805 Golgin subfamily A member 1 chr9 Not Cancer Driver No 1 biogrid 99 582 77 77 0
GPR17 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 Not Cancer Driver No 1 biogrid 57 16 4 4 0
GPR182 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 biogrid 49 33 4 4 0
GPR45 GPR45 Q9Y5Y3 Probable G-protein coupled receptor 45 chr2 Not Cancer Driver No 1 biogrid 97 0 0 0 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 intact 182 749 132 132 0
HOOK2 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 1 intact 94 487 62 62 0
INPP5E INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 Not Cancer Driver No 1 intact 43 272 16 16 15
KCTD3 KCTD3 Q9Y597 BTB/POZ domain-containing protein KCTD3 chr1 Not Cancer Driver No 1 intact 113 324 45 45 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 biogrid 67 291 28 28 3
KRT27 KRT27 Q7Z3Y8 Keratin, type I cytoskeletal 27 chr17 Not Cancer Driver No 1 biogrid 80 142 28 28 0
KRT38 KRT38 O76015 Keratin, type I cuticular Ha8 chr17 Not Cancer Driver No 1 biogrid 89 52 15 15 0
KRT8_ENST00000546897 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 biogrid 65 221 37 37 3
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 intact 114 404 58 58 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 biogrid 86 94 13 13 1
MAGEA8_ENST00000542674 MAGEA8 P43361 Melanoma-associated antigen 8 chrX Not Cancer Driver No 1 biogrid 65 112 19 19 0
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 1 intact 260 1212 220 220 0
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 2 intact, biogrid 94 543 52 52 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 intact 62 2 0 0 7
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 1 biogrid 26 109 11 11 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 1 biogrid 37 120 16 16 0
MAST3 MAST3 O60307 Microtubule-associated serine/threonine-protein kinase 3 chr19 Not Cancer Driver No 1 intact 169 783 100 100 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 Not Cancer Driver No 1 biogrid 80 313 45 45 0
NF1 NF1 P21359 Neurofibromin chr17 Census, Compendium Yes 1 intact 375 406 47 47 85
NUP62CL NUP62CL Q9H1M0 Nucleoporin-62 C-terminal-like protein chrX Not Cancer Driver No 1 biogrid 30 25 4 4 0
OPRL1_ENST00000336866 OPRL1 P41146 Nociceptin receptor chr20 Not Cancer Driver No 1 biogrid 81 0 0 0 0
P2RY10 P2RY10 O00398 Putative P2Y purinoceptor 10 chrX Not Cancer Driver No 1 biogrid 113 0 0 0 0
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 Census Yes 2 intact, biogrid 152 1665 134 134 0
PDCD1 PDCD1 Q15116 Programmed cell death protein 1 chr2 Not Cancer Driver No 1 intact, biogrid 56 141 37 37 0
PEX14 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 Not Cancer Driver No 1 biogrid 38 266 28 28 0
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 biogrid 16 7 1 1 3
PPA1 PPA1 Q15181 Inorganic pyrophosphatase chr10 Not Cancer Driver No 1 biogrid 31 24 0 0 0
PPA2 PPA2 Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial chr4 Not Cancer Driver No 1 biogrid 49 71 9 9 9
PRIMPOL_ENST00000503752 PRIMPOL Q96LW4 DNA-directed primase/polymerase protein chr4 Not Cancer Driver No 1 intact 50 92 7 7 0
PTH2R PTH2R P49190 Parathyroid hormone 2 receptor chr2 Not Cancer Driver No 1 biogrid 123 49 17 17 0
RCC1_ENST00000373833 RCC1 P18754 Regulator of chromosome condensation chr1 Not Cancer Driver No 3 intact, biogrid 54 143 15 15 0
RHOT2 RHOT2 Q8IXI1 Mitochondrial Rho GTPase 2 chr16 Not Cancer Driver No 1 biogrid 52 79 5 5 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 Not Cancer Driver No 1 intact 44 33 2 2 0
RSRC2 RSRC2 Q7L4I2 Arginine/serine-rich coiled-coil protein 2 chr12 Not Cancer Driver No 1 intact 58 401 54 54 0
SIPA1L1 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 Not Cancer Driver No 1 intact 321 1175 226 226 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 biogrid 54 267 32 32 30
SRSF12 SRSF12 Q8WXF0 Serine/arginine-rich splicing factor 12 chr6 Not Cancer Driver No 1 intact 36 205 31 31 0
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 biogrid 50 152 20 20 0
SYDE1 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 Not Cancer Driver No 1 intact 62 412 27 27 0
SYNE3 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 biogrid 143 236 42 42 0
TESK2 TESK2 Q96S53 Dual specificity testis-specific protein kinase 2 chr1 Not Cancer Driver No 1 intact 77 242 43 43 0
TRIM36 TRIM36 Q9NQ86 E3 ubiquitin-protein ligase TRIM36 chr5 Not Cancer Driver No 1 biogrid 106 89 21 21 1
UBXN6 UBXN6 Q9BZV1 UBX domain-containing protein 6 chr19 Not Cancer Driver No 1 biogrid 64 132 26 26 0
VAPB VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 Not Cancer Driver No 1 biogrid 16 138 8 8 3
VCL VCL P18206 Vinculin chr10 Not Cancer Driver No 1 biogrid 114 673 80 80 2
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 biogrid 84 316 57 57 1
WASHC3 WASHC3 Q9Y3C0 WASH complex subunit 3 chr12 Not Cancer Driver No 1 intact 29 100 8 8 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 3 intact, biogrid 22 109 4 4 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 intact, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 intact, biogrid 15 55 3 3 0
ZBTB21 ZBTB21 Q9ULJ3 Zinc finger and BTB domain-containing protein 21 chr21 Not Cancer Driver No 1 intact 136 645 75 75 0
ZNF638 ZNF638 Q14966 Zinc finger protein 638 chr2 Not Cancer Driver No 1 intact 243 1667 209 209 0