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NASP ,NASP ,P49321
  • Uniprot Accession= P49321
  • Ensembl Transcript= ENST00000350030.7
  • Uniprot Name= NASP
  • Name= Nuclear autoantigenic sperm protein
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 49
  • Number of Interaction partner in biogrid: 28
  • Number of Interaction partner in hippie: 98
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
AIRE AIRE O43918 Autoimmune regulator chr21 Not Cancer Driver No 1 hippie 71 338 48 48 19
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 intact, hippie 18 5 0 0 0
ARHGAP39_ENST00000276826 ARHGAP39 Q9C0H5 Rho GTPase-activating protein 39 chr8 Not Cancer Driver No 1 hippie, biogrid 120 613 61 61 0
ASF1A ASF1A Q9Y294 Histone chaperone ASF1A chr6 Not Cancer Driver No 5 hippie, biogrid 18 69 2 2 0
ASF1B ASF1B Q9NVP2 Histone chaperone ASF1B chr19 Not Cancer Driver No 4 hippie, biogrid 30 23 7 7 0
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 Compendium Yes 1 hippie 77 53 8 8 6
ATP6V1C1_ENST00000518738 ATP6V1C1 P21283 V-type proton ATPase subunit C 1 chr8 Not Cancer Driver No 1 hippie 54 17 3 3 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 biogrid 29 195 9 9 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BCAR3_ENST00000260502 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 Not Cancer Driver No 1 hippie 102 395 42 42 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
CABIN1 CABIN1 Q9Y6J0 Calcineurin-binding protein cabin-1 chr22 Not Cancer Driver No 1 hippie, biogrid 225 1008 95 95 0
CDAN1 CDAN1 Q8IWY9 Codanin-1 chr15 Not Cancer Driver No 1 hippie, biogrid 123 429 30 30 9
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 Not Cancer Driver No 1 hippie 76 91 5 5 0
CSTA CSTA P01040 Cystatin-A chr3 Not Cancer Driver No 1 hippie, biogrid 16 54 9 9 0
CTPS2_ENST00000380241 CTPS2 Q9NRF8 CTP synthase 2 chrX Not Cancer Driver No 1 hippie 57 65 9 9 0
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX Not Cancer Driver No 1 hippie, biogrid 62 145 29 29 24
DNAJC11 DNAJC11 Q9NVH1 DnaJ homolog subfamily C member 11 chr1 Not Cancer Driver No 1 hippie, biogrid 66 123 14 14 0
DONSON DONSON Q9NYP3 Protein downstream neighbor of Son chr21 Not Cancer Driver No 1 intact, hippie 50 217 13 13 6
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 107 59 6 6 2
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ETNK1 ETNK1 Q9HBU6 Ethanolamine kinase 1 chr12 Census Yes 2 intact, hippie, biogrid 49 81 5 5 0
FABP5 FABP5 Q01469 Fatty acid-binding protein 5 chr8 Not Cancer Driver No 1 hippie, biogrid 15 4 4 4 0
FTSJ1 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX Not Cancer Driver No 1 intact, hippie 44 89 14 14 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 1 intact, hippie 68 388 42 42 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
GSPT2 GSPT2 Q8IYD1 Eukaryotic peptide chain release factor GTP-binding subunit ERF3B chrX Not Cancer Driver No 1 hippie 108 270 47 47 0
H3F3C H3-5 Q6NXT2 Histone H3.3C chr12 Not Cancer Driver No 3 intact 38 50 10 10 0
HAT1 HAT1 O14929 Histone acetyltransferase type B catalytic subunit chr2 Not Cancer Driver No 2 intact, hippie, biogrid 51 14 2 2 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 intact, hippie 178 409 59 59 0
HIRA HIRA P54198 Protein HIRA chr22 Not Cancer Driver No 1 hippie, biogrid 138 288 37 37 0
HIST1H4A H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 15 31 5 5 0
HIST1H4B H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 29 31 6 6 0
HIST1H4C H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 29 31 7 7 0
HIST1H4D H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 32 31 8 8 0
HIST1H4E H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 45 31 14 14 0
HIST1H4F H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 30 31 7 7 0
HIST1H4H H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 22 31 9 9 0
HIST1H4I H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 33 31 10 10 0
HIST1H4J H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 26 31 9 9 0
HIST1H4K H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 44 31 13 13 0
HIST1H4L H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 2 intact 25 31 14 14 0
HIST2H3C H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 2 intact 1 51 0 0 0
HIST2H3D H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 2 intact 29 51 11 11 0
HIST2H3PS2 H3-7 Q5TEC6 Histone H3-7 chr1 Not Cancer Driver No 1 intact 4 51 2 2 0
HIST3H3 H3-4 Q16695 Histone H3.1t chr1 Not Cancer Driver No 1 intact 37 51 10 10 0
HIST4H4 H4-16 P62805 Histone H4 chr12 Not Cancer Driver No 2 intact 21 31 7 7 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 Compendium Yes 1 hippie 78 169 34 34 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 intact, hippie 108 76 13 13 0
KCNAB2_ENST00000378097 KCNAB2 Q13303 Voltage-gated potassium channel subunit beta-2 chr1 Not Cancer Driver No 1 intact, hippie 41 33 1 1 0
KIF17 KIF17 Q9P2E2 Kinesin-like protein KIF17 chr1 Not Cancer Driver No 1 hippie 191 600 113 113 0
KLF16 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 intact, hippie 13 204 8 8 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LUC7L2 LUC7L2 Q9Y383 Putative RNA-binding protein Luc7-like 2 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 59 262 45 45 0
MAGEL2 MAGEL2 Q9UJ55 MAGE-like protein 2 chr15 Not Cancer Driver No 1 hippie 178 1010 118 118 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 Not Cancer Driver No 1 intact, hippie 51 50 15 15 0
MAT2B MAT2B Q9NZL9 Methionine adenosyltransferase 2 subunit beta chr5 Not Cancer Driver No 1 hippie 42 59 8 8 0
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 136 589 92 92 0
MTNR1A MTNR1A P48039 Melatonin receptor type 1A chr4 Not Cancer Driver No 1 intact, hippie 72 0 0 0 0
MYLK MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 Not Cancer Driver No 1 intact, hippie, biogrid 343 957 184 184 3
MYLK4 MYLK4 Q86YV6 Myosin light chain kinase family member 4 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 67 77 14 14 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 123 117 42 42 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 35 23 0 0 0
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 230 881 150 150 0
NIPSNAP2 NIPSNAP2 O75323 Protein NipSnap homolog 2 chr7 Not Cancer Driver No 1 hippie 30 6 1 1 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
PAGE4_ENST00000376141 PAGE4 O60829 P antigen family member 4 chrX Not Cancer Driver No 1 hippie 20 102 20 20 0
PCYT1A_ENST00000431016 PCYT1A P49585 Choline-phosphate cytidylyltransferase A chr3 Not Cancer Driver No 1 hippie 52 145 25 25 6
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 Not Cancer Driver No 1 hippie 53 177 23 23 4
POLR2G POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 Not Cancer Driver No 1 intact, hippie 15 15 1 1 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 Compendium Yes 1 hippie 85 140 27 27 7
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 intact, hippie, biogrid 70 116 11 11 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 Not Cancer Driver No 1 intact, hippie 134 425 55 55 0
RBBP4 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 53 169 23 23 0
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX Not Cancer Driver No 1 intact, hippie 67 138 19 19 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie, biogrid 119 232 34 34 3
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 hippie 19 69 14 14 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 Census, Compendium Yes 1 intact, hippie 58 86 16 16 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 58 5 5 1
SLC43A3_ENST00000395124 SLC43A3 Q8NBI5 Equilibrative nucleobase transporter 1 chr11 Not Cancer Driver No 1 intact, hippie 75 32 2 2 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 Not Cancer Driver No 1 hippie 38 248 7 7 7
SNX1_ENST00000559844 SNX1 Q13596 Sorting nexin-1 chr15 Not Cancer Driver No 1 hippie 61 214 25 25 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 74 270 39 39 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 Not Cancer Driver No 1 intact, hippie 97 111 23 23 18
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TBCD TBCD Q9BTW9 Tubulin-specific chaperone D chr17 Not Cancer Driver No 1 hippie 156 60 9 9 11
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 1 hippie 33 361 20 20 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 1 hippie 28 310 16 16 0
TFE3 TFE3 P19532 Transcription factor E3 chrX Census Yes 1 intact, hippie 92 524 84 84 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 Not Cancer Driver No 1 hippie, biogrid 154 367 51 51 0
TLK2 TLK2 Q86UE8 Serine/threonine-protein kinase tousled-like 2 chr17 Not Cancer Driver No 1 hippie, biogrid 120 436 58 58 5
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 67 62 7 7 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UBN1 UBN1 Q9NPG3 Ubinuclein-1 chr16 Not Cancer Driver No 1 hippie, biogrid 118 943 105 105 0
UBN2 UBN2 Q6ZU65 Ubinuclein-2 chr7 Not Cancer Driver No 1 hippie, biogrid 157 1104 126 126 0
ULK2_ENST00000361658 ULK2 Q8IYT8 Serine/threonine-protein kinase ULK2 chr17 Not Cancer Driver No 1 hippie, biogrid 132 519 84 84 0
UNC13A UNC13A Q9UPW8 Protein unc-13 homolog A chr19 Not Cancer Driver No 1 hippie 300 454 78 78 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 1 intact 170 215 45 45 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie, biogrid 88 186 16 16 16
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 66 140 12 12 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0