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MTX1 ,MTX1 ,Q13505
  • Uniprot Accession= Q13505
  • Ensembl Transcript= ENST00000368376.7
  • Uniprot Name= MTX1
  • Name= Metaxin-1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 22
  • Number of Interaction partner in biogrid: 80
  • Number of Interaction partner in hippie: 110
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
A1BG A1BG P04217 Alpha-1B-glycoprotein chr19 Not Cancer Driver No 1 hippie 57 155 20 20 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 112 43 5 5 5
ADCK1 ADCK1 Q86TW2 AarF domain-containing protein kinase 1 chr14 Not Cancer Driver No 1 hippie, biogrid 82 6 3 3 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 88 166 22 22 11
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
AOX1 AOX1 Q06278 Aldehyde oxidase chr2 Not Cancer Driver No 1 intact 238 70 11 11 0
APLNR APLNR P35414 Apelin receptor chr11 Not Cancer Driver No 2 intact, hippie, biogrid 96 29 8 8 0
APOOL APOOL Q6UXV4 MICOS complex subunit MIC27 chrX Not Cancer Driver No 1 intact, hippie, biogrid 31 91 8 8 0
AQP3 AQP3 Q92482 Aquaporin-3 chr9 Not Cancer Driver No 1 hippie, biogrid 34 12 0 0 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 hippie 66 23 5 5 2
BSCL2_ENST00000421906 BSCL2 Q96G97 Seipin chr11 Not Cancer Driver No 1 hippie, biogrid 55 125 15 15 5
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 2 hippie, biogrid 43 123 17 17 0
C15orf48_ENST00000396650 NMES1 Q9C002 Normal mucosa of esophagus-specific gene 1 protein chr15 Not Cancer Driver No 1 intact 14 10 1 1 0
C19orf70_ENST00000309324 MICOS13 Q5XKP0 MICOS complex subunit MIC13 chr19 Not Cancer Driver No 1 intact, hippie 12 3 0 0 0
CACNG4 CACNG4 Q9UBN1 Voltage-dependent calcium channel gamma-4 subunit chr17 Not Cancer Driver No 3 hippie, biogrid 51 71 17 17 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 Not Cancer Driver No 1 hippie, biogrid 50 26 5 5 0
CISD1 CISD1 Q9NZ45 CDGSH iron-sulfur domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 6 18 0 0 0
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie, biogrid 73 409 55 55 0
CLN8 CLN8 Q9UBY8 Protein CLN8 chr8 Not Cancer Driver No 1 hippie 45 16 2 2 16
COQ10A COQ10A Q96MF6 Coenzyme Q-binding protein COQ10 homolog A, mitochondrial chr12 Not Cancer Driver No 1 hippie 27 28 0 0 0
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 43 111 13 13 0
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 15 23 6 6 2
COX7A2_ENST00000509698 COX7A2 D6RIE3 Cytochrome c oxidase subunit 7A2, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 5 13 3 3 0
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 hippie, biogrid 34 13 3 3 1
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 Not Cancer Driver No 1 hippie, biogrid 62 54 8 8 1
DNAJC10 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 Not Cancer Driver No 1 hippie, biogrid 110 36 3 3 0
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 Not Cancer Driver No 3 hippie, biogrid 62 21 6 6 2
EFNA4_ENST00000368409 EFNA4 P52798 Ephrin-A4 chr1 Not Cancer Driver No 1 hippie, biogrid 28 17 3 3 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 45 2 0 0 0
FPR1_ENST00000304748 FPR1 P21462 fMet-Leu-Phe receptor chr19 Not Cancer Driver No 1 hippie, biogrid 99 18 3 3 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
GCGR GCGR P47871 Glucagon receptor chr17 Not Cancer Driver No 1 hippie, biogrid 16 56 2 2 4
GHITM GHITM Q9H3K2 Growth hormone-inducible transmembrane protein chr10 Not Cancer Driver No 2 intact, hippie, biogrid 50 8 0 0 0
GLMP GLMP Q8WWB7 Glycosylated lysosomal membrane protein chr1 Not Cancer Driver No 1 intact, hippie 51 69 14 14 0
GNRH1_ENST00000421054 GNRH1 P01148 Progonadoliberin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 17 29 7 7 0
GPR12_ENST00000381436 GPR12 P47775 G-protein coupled receptor 12 chr13 Not Cancer Driver No 1 hippie, biogrid 69 0 0 0 0
GPR182 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 49 33 4 4 0
GPR45 GPR45 Q9Y5Y3 Probable G-protein coupled receptor 45 chr2 Not Cancer Driver No 1 hippie, biogrid 97 0 0 0 0
HCRTR2 HCRTR2 O43614 Orexin receptor type 2 chr6 Not Cancer Driver No 1 hippie, biogrid 154 38 13 13 0
HCST HCST Q9UBK5 Hematopoietic cell signal transducer chr19 Not Cancer Driver No 1 hippie, biogrid 6 12 0 0 0
HLA-C HLA-C P10321 HLA class I histocompatibility antigen, C alpha chain chr6 Not Cancer Driver No 1 hippie, biogrid 104 175 58 58 0
HLA-DPA1 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 Not Cancer Driver No 2 hippie, biogrid 37 30 4 4 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie, biogrid 39 206 19 19 0
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX Not Cancer Driver No 2 hippie, biogrid 140 40 11 11 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie 44 127 9 9 2
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 Not Cancer Driver No 1 hippie, biogrid 51 131 29 29 2
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie 97 400 50 50 0
KCNIP4 KCNIP4 Q6PIL6 Kv channel-interacting protein 4 chr4 Not Cancer Driver No 3 intact, hippie, biogrid 59 30 13 13 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LPAR4 LPAR4 Q99677 Lysophosphatidic acid receptor 4 chrX Compendium Yes 2 hippie, biogrid 123 10 3 3 0
LPCAT2 LPCAT2 Q7L5N7 Lysophosphatidylcholine acyltransferase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 78 35 5 5 0
LYPD3 LYPD3 O95274 Ly6/PLAUR domain-containing protein 3 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 52 116 15 15 0
MAGEA8_ENST00000542674 MAGEA8 P43361 Melanoma-associated antigen 8 chrX Not Cancer Driver No 1 hippie, biogrid 65 112 19 19 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 hippie 10 17 1 1 0
MAP1LC3C MAP1LC3C Q9BXW4 Microtubule-associated proteins 1A/1B light chain 3C chr1 Not Cancer Driver No 1 hippie 32 31 5 5 0
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 Not Cancer Driver No 2 intact, hippie, biogrid 47 5 2 2 0
MFSD4A MFSD4A Q8N468 Major facilitator superfamily domain-containing protein 4A chr1 Not Cancer Driver No 1 hippie 56 29 3 3 0
MICB MICB Q29980 MHC class I polypeptide-related sequence B chr6 Not Cancer Driver No 1 hippie, biogrid 56 175 22 22 0
MINOS1 MICOS10 Q5TGZ0 MICOS complex subunit MIC10 chr1 Not Cancer Driver No 1 hippie 5 0 0 0 0
MLNR MLNR O43193 Motilin receptor chr13 Not Cancer Driver No 1 hippie, biogrid 43 66 6 6 0
MTX2 MTX2 O75431 Metaxin-2 chr2 Not Cancer Driver No 2 intact, hippie 33 0 0 0 0
NDUFB5 NDUFB5 O43674 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 28 9 1 1 0
NDUFS1_ENST00000449699 NDUFS1 P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 81 40 3 3 2
NDUFV1 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 66 57 9 9 3
NECAB1 NECAB1 Q8N987 N-terminal EF-hand calcium-binding protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 54 135 21 21 0
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 2 hippie, biogrid 37 169 25 25 0
OMA1 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 52 34 4 4 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 114 131 17 17 60
OPA3_ENST00000263275 OPA3 Q9H6K4 Optic atrophy 3 protein chr19 Not Cancer Driver No 1 hippie 18 44 7 7 2
OPRL1_ENST00000336866 OPRL1 P41146 Nociceptin receptor chr20 Not Cancer Driver No 1 hippie, biogrid 81 0 0 0 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
P2RY10 P2RY10 O00398 Putative P2Y purinoceptor 10 chrX Not Cancer Driver No 1 hippie, biogrid 113 0 0 0 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 31 26 4 4 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLXNA4 PLXNA4 Q9HCM2 Plexin-A4 chr7 Not Cancer Driver No 1 hippie, biogrid 591 198 63 63 0
POMK POMK Q9H5K3 Protein O-mannose kinase chr8 Not Cancer Driver No 1 hippie, biogrid 53 30 9 9 3
POTEF POTEF A5A3E0 POTE ankyrin domain family member F chr2 Not Cancer Driver No 1 hippie, biogrid 269 453 93 93 0
PRELID3B PRELID3B Q9Y3B1 PRELI domain containing protein 3B chr20 Not Cancer Driver No 1 hippie 20 72 9 9 0
PTH1R_ENST00000449590 PTH1R Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor chr3 Not Cancer Driver No 1 hippie, biogrid 86 124 25 25 5
PTH2R PTH2R P49190 Parathyroid hormone 2 receptor chr2 Not Cancer Driver No 1 hippie, biogrid 123 49 17 17 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 53 26 4 4 0
SAMM50 SAMM50 Q9Y512 Sorting and assembly machinery component 50 homolog chr22 Not Cancer Driver No 1 intact, hippie 51 34 1 1 0
SCCPDH SCCPDH Q8NBX0 Saccharopine dehydrogenase-like oxidoreductase chr1 Not Cancer Driver No 1 hippie, biogrid 56 26 1 1 0
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 intact, hippie 31 29 1 1 0
SIGLEC12 SIGLEC12 Q96PQ1 Sialic acid-binding Ig-like lectin 12 chr19 Not Cancer Driver No 2 hippie, biogrid 150 213 56 56 0
SLC15A1 SLC15A1 P46059 Solute carrier family 15 member 1 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 122 24 7 7 0
SLC18A2_ENST00000644641 SLC18A2 Q05940 Synaptic vesicular amine transporter chr10 Not Cancer Driver No 1 hippie, biogrid 105 23 7 7 1
SLC25A46 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 Not Cancer Driver No 1 hippie 37 96 2 2 4
SLC26A6 SLC26A6 Q9BXS9 Solute carrier family 26 member 6 chr3 Not Cancer Driver No 1 hippie, biogrid 68 87 13 13 0
SLC2A12 SLC2A12 Q8TD20 Solute carrier family 2, facilitated glucose transporter member 12 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 87 52 4 4 0
SLC39A12 SLC39A12 Q504Y0 Zinc transporter ZIP12 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 210 89 29 29 0
SLC39A9 SLC39A9 Q9NUM3 Zinc transporter ZIP9 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 34 44 4 4 0
SLC5A6 SLC5A6 Q9Y289 Sodium-dependent multivitamin transporter chr2 Not Cancer Driver No 1 hippie, biogrid 87 28 0 0 2
SLCO4C1 SLCO4C1 Q6ZQN7 Solute carrier organic anion transporter family member 4C1 chr5 Not Cancer Driver No 1 hippie, biogrid 129 86 10 10 0
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 Not Cancer Driver No 1 hippie, biogrid 315 980 114 114 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 Not Cancer Driver No 1 hippie, biogrid 311 869 123 123 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SURF1 SURF1 Q15526 Surfeit locus protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 17 82 6 6 11
TMBIM4_ENST00000358230 TMBIM4 Q9HC24 Protein lifeguard 4 chr12 Not Cancer Driver No 1 hippie, biogrid 36 3 0 0 0
TMEM108 TMEM108 Q6UXF1 Transmembrane protein 108 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 101 458 89 89 0
TMEM171 TMEM171 Q8WVE6 Transmembrane protein 171 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 54 150 18 18 0
TOMM22 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 18 83 9 9 0
TOMM40_ENST00000405636 TOMM40 O96008 Mitochondrial import receptor subunit TOM40 homolog chr19 Not Cancer Driver No 1 hippie 17 98 1 1 0
TOMM5_ENST00000321301 TOMM5 Q8N4H5 Mitochondrial import receptor subunit TOM5 homolog chr9 Not Cancer Driver No 1 hippie, biogrid 4 0 0 0 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
UQCRC1 UQCRC1 P31930 Cytochrome b-c1 complex subunit 1, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 57 55 6 6 2
UQCRC2 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 53 48 13 13 1
VIPR2 VIPR2 P41587 Vasoactive intestinal polypeptide receptor 2 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 74 0 0 0 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0