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MTR ,MTR ,Q99707
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 52
  • Number of Interaction partner in hippie: 95
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AKAP13_ENST00000394518 AKAP13 Q12802 A-kinase anchor protein 13 chr15 Not Cancer Driver No 3 hippie, biogrid 359 2091 258 258 0
ALDH3B1 ALDH3B1 P43353 Aldehyde dehydrogenase family 3 member B1 chr11 Not Cancer Driver No 1 hippie, biogrid 36 23 6 6 0
ANAPC2 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 Not Cancer Driver No 1 hippie, biogrid 104 146 26 26 0
ANKRD13A ANKRD13A Q8IZ07 Ankyrin repeat domain-containing protein 13A chr12 Not Cancer Driver No 1 hippie, biogrid 54 167 16 16 0
ARL4D ARL4D P49703 ADP-ribosylation factor-like protein 4D chr17 Not Cancer Driver No 1 hippie, biogrid 31 30 3 3 0
ARPC1A ARPC1A Q92747 Actin-related protein 2/3 complex subunit 1A chr7 Not Cancer Driver No 1 hippie 48 27 7 7 0
ARPC2_ENST00000315717 ARPC2 O15144 Actin-related protein 2/3 complex subunit 2 chr2 Not Cancer Driver No 1 hippie 40 49 8 8 0
B9D1 B9D1 Q9UPM9 B9 domain-containing protein 1 chr17 Not Cancer Driver No 1 hippie 16 51 6 6 2
B9D2 B9D2 Q9BPU9 B9 domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie 36 4 4 4 1
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 80 45 4 4 0
C12orf74_ENST00000544406 C12orf74 Q6ZR37-3 Isoform 3 of Pleckstrin homology domain-containing family G member 7 chr12 Not Cancer Driver No 1 hippie, biogrid 29 159 26 26 0
C6orf141 C6orf141 Q5SZD1 Uncharacterized protein C6orf141 chr6 Not Cancer Driver No 1 hippie, biogrid 12 226 9 9 0
CALU_ENST00000249364 CALU O43852 Calumenin chr7 Not Cancer Driver No 1 hippie 34 130 12 12 0
CDK18_ENST00000360066 CDK18 Q07002 Cyclin-dependent kinase 18 chr1 Not Cancer Driver No 1 hippie 64 132 17 17 0
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 Census, Compendium Yes 1 hippie 166 83 88 88 36
CEP19 CEP19 Q96LK0 Centrosomal protein of 19 kDa chr3 Not Cancer Driver No 1 hippie 30 71 11 11 0
DHFR DHFR P00374 Dihydrofolate reductase chr5 Not Cancer Driver No 1 hippie, biogrid 16 12 2 2 2
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 Not Cancer Driver No 1 hippie 25 20 0 0 0
DHX16 DHX16 O60231 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 chr6 Not Cancer Driver No 1 hippie, biogrid 128 391 59 59 1
DNAJB2 DNAJB2 P25686 DnaJ homolog subfamily B member 2 chr2 Not Cancer Driver No 1 hippie, biogrid 51 239 40 40 1
DNAJC7 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 hippie, biogrid 41 102 9 9 0
DOCK5 DOCK5 Q9H7D0 Dedicator of cytokinesis protein 5 chr8 Not Cancer Driver No 2 hippie, biogrid 278 330 45 45 0
DPP9_ENST00000598800 DPP9 Q86TI2 Dipeptidyl peptidase 9 chr19 Not Cancer Driver No 1 hippie 94 83 15 15 0
DYNLL1_ENST00000242577 DYNLL1 P63167 Dynein light chain 1, cytoplasmic chr12 Not Cancer Driver No 1 hippie 9 0 0 0 0
EEF1AKMT3 EEF1AKMT3 Q96AZ1 EEF1A lysine methyltransferase 3 chr12 Not Cancer Driver No 1 hippie 23 33 1 1 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 Not Cancer Driver No 1 hippie, biogrid 125 669 69 69 0
F12 F12 P00748 Coagulation factor XII chr5 Not Cancer Driver No 1 hippie, biogrid 53 104 9 9 13
GRK6_ENST00000355472 GRK6 P43250 G protein-coupled receptor kinase 6 chr5 Not Cancer Driver No 1 hippie, biogrid 65 68 10 10 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 Not Cancer Driver No 1 hippie, biogrid 44 219 32 32 2
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
ILF2 ILF2 Q12905 Interleukin enhancer-binding factor 2 chr1 Not Cancer Driver No 1 hippie, biogrid 36 92 9 9 0
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 45 71 9 9 0
INF2 INF2 Q27J81 Inverted formin-2 chr14 Not Cancer Driver No 1 hippie, biogrid 120 635 49 49 30
IQCF1 IQCF1 Q8N6M8 IQ domain-containing protein F1 chr3 Not Cancer Driver No 1 hippie, biogrid 43 70 16 16 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX Compendium Yes 1 hippie, biogrid 71 337 39 39 0
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 Census, Compendium Yes 1 hippie, biogrid 167 63 10 10 7
KLHL14 KLHL14 Q9P2G3 Kelch-like protein 14 chr18 Not Cancer Driver No 1 hippie, biogrid 117 81 10 10 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LGI1 LGI1 O95970 Leucine-rich glioma-inactivated protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 87 3 1 1 17
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 Not Cancer Driver No 1 hippie, biogrid 110 170 30 30 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LPCAT1 LPCAT1 Q8NF37 Lysophosphatidylcholine acyltransferase 1 chr5 Not Cancer Driver No 1 hippie, biogrid 85 66 11 11 0
LRRC27 LRRC27 Q9C0I9 Leucine-rich repeat-containing protein 27 chr10 Not Cancer Driver No 1 hippie, biogrid 80 350 53 53 0
LSM4 LSM4 Q9Y4Z0 U6 snRNA-associated Sm-like protein LSm4 chr19 Not Cancer Driver No 1 hippie, biogrid 19 64 9 9 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 Compendium Yes 1 hippie, biogrid 89 144 20 20 0
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 Not Cancer Driver No 1 hippie 116 276 41 41 0
MMACHC MMACHC Q9Y4U1 Cyanocobalamin reductase / alkylcobalamin dealkylase chr1 Not Cancer Driver No 1 hippie 29 85 5 5 14
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MTRR_ENST00000440940 MTRR Q9UBK8 Methionine synthase reductase chr5 Not Cancer Driver No 1 hippie 101 84 13 13 5
NAPG NAPG Q99747 Gamma-soluble NSF attachment protein chr18 Not Cancer Driver No 1 hippie, biogrid 35 56 3 3 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie, biogrid 78 492 49 49 0
NEK8 NEK8 Q86SG6 Serine/threonine-protein kinase Nek8 chr17 Not Cancer Driver No 2 hippie, biogrid 102 167 40 40 3
NFYC NFYC Q13952 Nuclear transcription factor Y subunit gamma chr1 Not Cancer Driver No 1 hippie 46 320 32 32 0
NPAS1_ENST00000449844 NPAS1 Q99742 Neuronal PAS domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 53 309 23 23 0
NPRL3_ENST00000611875 NPRL3 Q12980 GATOR complex protein NPRL3 chr16 Not Cancer Driver No 1 hippie, biogrid 45 158 22 22 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
NRBP2 NRBP2 Q9NSY0 Nuclear receptor-binding protein 2 chr8 Not Cancer Driver No 1 hippie, biogrid 30 110 5 5 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 16 7 1 1 3
PLEC PLEC Q15149 Plectin chr8 Not Cancer Driver No 1 hippie 677 2130 272 272 2
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX Not Cancer Driver No 1 hippie, biogrid 56 4 1 1 0
PSKH2 PSKH2 Q96QS6 Serine/threonine-protein kinase H2 chr8 Not Cancer Driver No 1 hippie, biogrid 86 87 19 19 0
RAD51B_ENST00000487270 RAD51B O15315 DNA repair protein RAD51 homolog 2 chr14 Census Yes 1 hippie, biogrid 45 13 0 0 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 hippie, biogrid 89 169 38 38 22
RCCD1_ENST00000556618 RCCD1 A6NED2 RCC1 domain-containing protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 17 105 3 3 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 41 12 3 3 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 hippie 119 232 34 34 3
SHARPIN SHARPIN Q9H0F6 Sharpin chr8 Not Cancer Driver No 1 hippie 34 237 16 16 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 hippie 198 195 17 17 8
SOHLH1_ENST00000298466 SOHLH1 Q5JUK2 Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 48 252 39 39 0
SOX12 SOX12 O15370 Transcription factor SOX-12 chr20 Not Cancer Driver No 1 hippie, biogrid 20 307 19 19 0
SPATA5L1 SPATA5L1 Q9BVQ7 Spermatogenesis-associated protein 5-like protein 1 chr15 Not Cancer Driver No 2 hippie, biogrid 62 166 13 13 0
SRMS SRMS Q9H3Y6 Tyrosine-protein kinase Srms chr20 Not Cancer Driver No 1 hippie, biogrid 77 48 11 11 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
TDRD3_ENST00000196169 TDRD3 Q9H7E2 Tudor domain-containing protein 3 chr13 Not Cancer Driver No 1 hippie 97 518 77 77 0
TFDP3 TFDP3 Q5H9I0 Transcription factor Dp family member 3 chrX Not Cancer Driver No 1 hippie, biogrid 84 186 42 42 0
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 Census, Compendium Yes 1 hippie 106 60 16 16 25
THG1L THG1L Q9NWX6 Probable tRNA(His) guanylyltransferase chr5 Not Cancer Driver No 1 hippie 32 22 2 2 1
TPD52L2_ENST00000346249 TPD52L2 O43399 Tumor protein D54 chr20 Not Cancer Driver No 1 hippie 25 180 22 22 0
TRIM66_ENST00000299550 TRIM66 O15016 Tripartite motif-containing protein 66 chr11 Not Cancer Driver No 1 hippie 58 723 32 32 0
TSC22D1 TSC22D1 Q15714 TSC22 domain family protein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 110 1023 98 98 0
TSSK6 TSSK6 Q9BXA6 Testis-specific serine/threonine-protein kinase 6 chr19 Not Cancer Driver No 1 hippie, biogrid 47 0 0 0 0
UBD UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 31 8 1 1 0
UBXN6 UBXN6 Q9BZV1 UBX domain-containing protein 6 chr19 Not Cancer Driver No 1 hippie, biogrid 64 132 26 26 0
ULK4 ULK4 Q96C45 Serine/threonine-protein kinase ULK4 chr3 Not Cancer Driver No 1 hippie, biogrid 162 180 33 33 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VWA2 VWA2 Q5GFL6 von Willebrand factor A domain-containing protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 105 82 14 14 0
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 Not Cancer Driver No 1 hippie 24 35 2 2 1